@article{SchuhmacherWilischKussetal.2021, author = {Schuhmacher, Alexander and Wilisch, Lucas and Kuss, Michael and Kandelbauer, Andreas and Hinder, Markus and Gassmann, Oliver}, title = {R\&D efficiency of leading pharmaceutical companies : a 20-year analysis}, journal = {Drug discovery today}, volume = {26}, number = {8}, issn = {1359-6446}, doi = {10.1016/j.drudis.2021.05.005}, institution = {Life Sciences}, pages = {1784 -- 1789}, year = {2021}, abstract = {Comparative analysis of the R\&D efficiency of 14 leading pharmaceutical companies for the years 1999-2018 shows that there is a close positive correlation between R\&D spending and the two investigated R\&D output parameters, approved NMEs and the cumulative impact factor of their publications. In other words, higher R\&D investments (input) were associated with higher R\&D output. Second, our analyses indicate that there are "economies of scale" (size) in pharmaceutical R\&D.}, language = {en} }