@article{UllahKhanRenetal.2021,
  author    = {Ullah, Sadeeq and Khan, Shahin and Ren, Yanru and Zhang, Xu and Qin, Meng and Xiong, Xin and Krastev, Rumen and Jan, Amin and Liu, Luo and Yuan, Qipeng},
  title     = {Near-infrared laser 808-nm excitable palladium nano-dots loaded on graphene oxide hybrid for the antibacterial activity},
  journal   = {Applied organometallic chemistry},
  volume    = {35},
  number    = {11},
  doi       = {10.1002/aoc.6380},
  institution = {Life Sciences},
  pages     = {e6380},
  year      = {2021},
  abstract  = {Escherichia coli (E. coli) is considered the most common life-threatening infectious bacteria in our daily life and poses a major challenge to human health. However, antibiotics frequently overused and misused has triggered increased multidrug resistance, hinders therapeutic outcomes, and causes higher mortalities. Herein, we addressed near-infrared (NIR) laser-excited human serum albumin (HSA) mediated graphene oxide loaded palladium nano-dots (HSA-GO-Pd) that can effectively combat Gram-negative E. coli in vitro. NIR laser-excited designed hybrid material highly generates singlet oxygen and hydroxyl radical by electron spin-resonance (ESR) analysis. Transmission electron microscope (TEM) images show small spherical sizes PdNPs on the surface of GO nano-sheets. The zeta (ζ) potential study indicates that in an aqueous medium, the average PdNPs size and surface capped charge comes from human body protein (HSA), HSA-GO-Pd is 5-8 nm, and +25 mV, respectively. The spectroscopic characterization reveals that in the synthesized HSA-GO-Pd nanocomposite, PdNPs successfully well-dispersed decorated on the surface of graphene oxide. The as-synthesized HSA-GO-Pd shows excellent antibacterial activity against gram-negative pathogen by killing 95\% bacteria within 5 h. HSA-GO-Pd having very biocompatible and shows significant antibacterial activities. Owing to their intense photothermal conversation potential, low toxicity to normal cells, the as-addressed hybrid (HSA-GO-Pd) combined with NIR-irradiation will catch up valuable insight into the effective ablation of pathogenic bacteria.},
  language  = {en}
}