TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Seidenstuecker, Michael A1 - Lange, Svenja A1 - Esslinger, Steffen A1 - Latorre, Sergio A1 - Krastev, Rumen A1 - Gadow, Rainer T1 - Inversely 3D-printed β-TCP scaffolds for bone replacement JF - Materials N2 - The aim of this study was to predefine the pore structure of β-tricalcium phosphate (β-TCP) scaffolds with different macro pore sizes (500, 750, and 1000 µm), to characterize β-TCP scaffolds, and to investigate the growth behavior of cells within these scaffolds. The lead structures for directional bone growth (sacrificial structures) were produced from polylactide (PLA) using the fused deposition modeling techniques. The molds were then filled with β-TCP slurry and sintered at 1250° C, whereby the lead structures (voids) were burnt out. The scaffolds were mechanically characterized (native and after incubation in simulated body fluid (SBF) for 28 d). In addition, biocompatibility was investigated by live/dead, cell proliferation and lactate dehydrogenase assays. KW - FDM KW - inversely KW - β-TCP KW - bone replacement Y1 - 2019 UN - https://nbn-resolving.org/urn:nbn:de:bsz:rt2-opus4-25486 SN - 1996-1944 SS - 1996-1944 U6 - https://doi.org/10.3390/ma12203417 DO - https://doi.org/10.3390/ma12203417 VL - 12 IS - 20 SP - 1 EP - 17 S1 - 17 PB - MDPI CY - Basel ER -