TY  - JOUR
U1  - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed)
A1  - Djanklich, Leyla
A1  - Andreeva, Tonya
A1  - Xiong, Xin
A1  - Krastev, Rumen
A1  - Kemkemer, Ralf
T1  - Evaluation of antibacterial properties of polyelectrolyte multilayer coatings by norm tests
JF  - Current directions in biomedical engineering
N2  - Medical implants play a central role in modern medicine and both, naturally derived and synthetic materials have been explored as biomaterials for such devices. However, when implanted into living tissue, most materials initiate a host response. In addition, implants often cause bacterial infections leading to complications. Polyelectrolyte multilayer (PEM) coatings can be used for functionalization of medical implants improving the implant integration and reducing foreign body reactions. Some PEMs are also known to show antibacterial  properties. We developed a PEM coating suggesting that it can decrease the risk of bacterial infections occurring after implantation while being highly biocompatible. We applied two different standard tests for evaluating the PEM’s antibacterial properties, the ISO norm (ISO 22196) and one ASTM norm (ASTM E2180) test. We found a reduction of bacterial growth on the PEM but to a different degree depending on the testing method. This result demonstrates the need for defining proper method to evaluate antibacterial properties of surface coatings.
KW  - polyelectrolyte multilayer coatings
KW  - implants
KW  - antibacterial coating
KW  - norm tests
Y1  - 2020
UN  - https://nbn-resolving.org/urn:nbn:de:bsz:rt2-opus4-30100
SN  - 2364-5504
SS  - 2364-5504
U6  - https://doi.org/10.1515/cdbme-2020-3122
DO  - https://doi.org/10.1515/cdbme-2020-3122
VL  - 6
IS  - 3
SP  - 1
EP  - 4
S1  - 4
PB  - De Gruyter
CY  - Berlin
ER  -