TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Andreeva, Tonya A1 - Hartmann, Hanna A1 - Taneva, Stefka A1 - Krastev, Rumen T1 - Regulation of the growth, morphology, mechanical properties and biocompatibility of natural polysaccharide-based multilayers by Hofmeister anions JF - Journal of materials chemistry. - B. Materials for biology and medicine N2 - Herein the optimization of the physicochemical properties and surface biocompatibility of polyelectrolyte multilayers of the natural, biocompatible and biodegradable, linear polysaccharides hyaluronan and chitosan by Hofmeister anions was systematically investigated. We demonstrated that there is an interconnection between the bulk and surface properties of HA/Chi multilayers both varying in accordance with the arrangement of the anions in the Hofmeister series. Kosmotropic anions increased the hydration, thickness, micro- and macro-roughness, and hydrophilicity and improved the biocompatibility of the films by reduction (2 orders of magnitude) of the films stiffness and complete anti-thrombogenicity. Y1 - 2016 SN - 1552-4973 SS - 1552-4973 U6 - https://doi.org/10.1039/C6TB01638C DO - https://doi.org/10.1039/C6TB01638C VL - 4 IS - 44 SP - 7092 EP - 7100 S1 - 9 PB - The Royal Society of Chemistry CY - Cambridge ER -