TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Ostertag, Edwin A1 - Stefanakis, Mona A1 - Rebner, Karsten A1 - Kessler, Rudolf T1 - Elastic and inelastic light scattering spectroscopy and its possible use for label-free brain tumor typing JF - Analytical and bioanalytical chemistry N2 - This paper presents an approach for label-free brain tumor tissue typing. For this application, our dual modality microspectroscopy system combines inelastic Raman scattering spectroscopy and Mie elastic light scattering spectroscopy. The system enables marker-free biomedical diagnostics and records both the chemical and morphologic changes of tissues on a cellular and subcellular level. The system setup is described and the suitability for measuring morphologic features is investigated. KW - Mie elastic light scattering spectroscopy KW - Raman inelastic light scattering spectroscopy KW - bimodal KW - multi-spectroscopy KW - label-free KW - brain tumor typing Y1 - 2017 SN - 1618-2642 SS - 1618-2642 U6 - https://doi.org/10.1007/s00216-017-0614-1 DO - https://doi.org/10.1007/s00216-017-0614-1 VL - 409 IS - 28 SP - 6613 EP - 6623 S1 - 11 PB - Springer CY - Berlin ; Heidelberg ER -