TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Zeineldin, Ramy A1 - Karar, Mohamed Esmail A1 - Coburger, Jan A1 - Wirtz, Christian A1 - Mathis-Ullrich, Franziska A1 - Burgert, Oliver T1 - Towards automated correction of brain shift using deep deformable magnetic resonance imaging-intraoperative ultrasound (MRI-iUS) registration JF - Current directions in biomedical engineering N2 - Intraoperative brain deformation, so called brain shift, affects the applicability of preoperative magnetic resonance imaging (MRI) data to assist the procedures of intraoperative ultrasound (iUS) guidance during neurosurgery. This paper proposes a deep learning-based approach for fast and accurate deformable registration of preoperative MRI to iUS images to correct brain shift. Based on the architecture of 3D convolutional neural networks, the proposed deep MRI-iUS registration method has been successfully tested and evaluated on the retrospective evaluation of cerebral tumors (RESECT) dataset. This study showed that our proposed method outperforms other registration methods in previous studies with an average mean squared error (MSE) of 85. Moreover, this method can register three 3D MRI-US pair in less than a second, improving the expected outcomes of brain surgery. KW - biomedical image processing KW - brain shift KW - deep learning KW - image-guided neurosurgery KW - MRI-iUS Y1 - 2020 UN - https://nbn-resolving.org/urn:nbn:de:bsz:rt2-opus4-27906 SN - 2364-5504 SS - 2364-5504 U6 - https://doi.org/10.1515/cdbme-2020-0039 DO - https://doi.org/10.1515/cdbme-2020-0039 VL - 6 IS - 1 SP - 1 EP - 5 S1 - 5 PB - De Gruyter CY - Berlin ER -