TY  - JOUR
U1  - Wissenschaftlicher Artikel
A1  - Fait, Fabio
A1  - Wagner, Stephanie
A1  - Steinbach, Julia
A1  - Kandelbauer, Andreas
A1  - Mayer, Hermann
T1  - Tailoring the morphology of monodisperse mesoporous silica particles using different alkoxysilanes as silica precursors
JF  - International journal of molecular sciences
N2  - The hard template method for the preparation of monodisperse mesoporous silica microspheres (MPSMs) has been established in recent years. In this process, in situ-generated silica nanoparticles (SNPs) enter the porous organic template and control the size and pore parameters of the final MPSMs. Here, the sizes of the deposited SNPs are determined by the hydrolysis and condensation rates of different alkoxysilanes in a base catalyzed sol–gel process. Thus, tetramethyl orthosilicate (TMOS), tetraethyl orthosilicate (TEOS), tetrapropyl orthosilicate (TPOS) and tetrabutyl orthosilicate (TBOS) were sol–gel processed in the presence of amino-functionalized poly (glycidyl methacrylate-co-ethylene glycol dimethacrylate) (p(GMA-co-EDMA)) templates. The size of the final MPSMs covers a broad range of 0.5–7.3 µm and a median pore size distribution from 4.0 to 24.9 nm. Moreover, the specific surface area can be adjusted between 271 and 637 m2 g−1. Also, the properties and morphology of the MPSMs differ according to the SNPs. Furthermore, the combination of different alkoxysilanes allows the individual design of the morphology and pore parameters of the silica particles. Selected MPSMs were packed into columns and successfully applied as stationary phases in high-performance liquid chromatography (HPLC) in the separation of various water-soluble vitamins.
KW  - mesoporous silica microspheres (MPSMs)
KW  - hard template method
KW  - high-performance liquid chromatography (HPLC)
Y1  - 2023
UN  - https://nbn-resolving.org/urn:nbn:de:bsz:rt2-opus4-47757
SN  - 1422-0067
SS  - 1422-0067
U6  - https://doi.org/10.3390/ijms241411729
DO  - https://doi.org/10.3390/ijms241411729
VL  - 24
IS  - 14
SP  - 12
S1  - 12
PB  - MDPI
CY  - Basel
ER  -