TY  - JOUR
A1  - Andreeva, Tonya
A1  - Hartmann, Hanna
A1  - Taneva, Stefka
A1  - Krastev, Rumen
T1  - Regulation of the growth, morphology, mechanical properties and biocompatibility of natural polysaccharide-based multilayers by Hofmeister anions
JF  - Journal of materials chemistry. - B. Materials for biology and medicine
N2  - Herein the optimization of the physicochemical properties and surface biocompatibility of polyelectrolyte multilayers of the natural, biocompatible and biodegradable, linear polysaccharides hyaluronan and chitosan by Hofmeister anions was systematically investigated. We demonstrated that there is an interconnection between the bulk and surface properties of HA/Chi multilayers both varying in accordance with the arrangement of the anions in the Hofmeister series. Kosmotropic anions increased the hydration, thickness, micro- and macro-roughness, and hydrophilicity and improved the biocompatibility of the films by reduction (2 orders of magnitude) of the films stiffness and complete anti-thrombogenicity.
Y1  - 2017
U6  - http://dx.doi.org/10.1039/C6TB01638C
SN  - 1552-4973
VL  - 4
IS  - 44
SP  - 7092
EP  - 7100
PB  - The Royal Society of Chemistry
CY  - Cambridge
ER  -