TY - JOUR A1 - Andreeva, Tonya A1 - Hartmann, Hanna A1 - Taneva, Stefka A1 - Krastev, Rumen T1 - Regulation of the growth, morphology, mechanical properties and biocompatibility of natural polysaccharide-based multilayers by Hofmeister anions JF - Journal of materials chemistry. - B. Materials for biology and medicine N2 - Herein the optimization of the physicochemical properties and surface biocompatibility of polyelectrolyte multilayers of the natural, biocompatible and biodegradable, linear polysaccharides hyaluronan and chitosan by Hofmeister anions was systematically investigated. We demonstrated that there is an interconnection between the bulk and surface properties of HA/Chi multilayers both varying in accordance with the arrangement of the anions in the Hofmeister series. Kosmotropic anions increased the hydration, thickness, micro- and macro-roughness, and hydrophilicity and improved the biocompatibility of the films by reduction (2 orders of magnitude) of the films stiffness and complete anti-thrombogenicity. Y1 - 2017 U6 - http://dx.doi.org/10.1039/C6TB01638C SN - 1552-4973 VL - 4 IS - 44 SP - 7092 EP - 7100 PB - The Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Andreeva, Tonya A1 - Danailova, Avgustina A1 - Terziyska, Penka A1 - Krumova, Shashka A1 - Taneva, Stefka A1 - Krastev, Rumen T1 - Hofmeister anions effect on the thickness and morphology of polyelectrolyte multilayers for biofunctionalization of cardiovascular stents JF - Bulgarian chemical communications N2 - The effect of Hofmeister anions on the surface properties of polyelectrolyte multilayers built from hyaluronan and chitosan by layer-by-layer deposition is studied by ellipsometry and atomic force microscopy. The thickness, roughness and morphology of the resulting coatings were found to depend on the type of the anion. Relationship between the surface properties and the biological response of the polyelectrolyte multilayers is established by assessing the degree of protein (albumin) adsorption. KW - polyelectrolyte multilayers KW - ellipsometry KW - AFM KW - Hofmeister anions Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bsz:rt2-opus4-11749 UR - http://www.bcc.bas.bg/ VL - 48 IS - Special issue A SP - 23 EP - 28 PB - BAN CY - Sofia ER -