Generation of an azide-modified extracellular matrix by adipose-derived stem cells using metabolic glycoengineering
- Natural extracellular matrix (ECM) represents an ideal biomaterial for tissue engineering and regenerative medicine approaches. For further functionalization, there is a need for specific addressable functional groups within this biomaterial. Metabolic glycoengineering (MGE) provides a technique to incorporate modified monosaccharide derivatives into the ECM during their assembly, which was shown by us earlier for the production of a modified fibroblast-derived dermal ECM.
| Author of HS Reutlingen | Nellinger, Svenja; Volz, Ann-Cathrin; Kluger, Petra |
|---|---|
| URN: | urn:nbn:de:bsz:rt2-opus4-25648 |
| DOI: | https://doi.org/10.1515/cdbme-2019-0099 |
| ISSN: | 2364-5504 |
| Erschienen in: | Current directions in biomedical engineering |
| Publisher: | De Gruyter |
| Place of publication: | Berlin |
| Document Type: | Journal article |
| Language: | English |
| Publication year: | 2019 |
| Tag: | adipose-derived stem cells; azide-modified; clickECM; extracellular matrix; metabolic glycoengineering |
| Volume: | 5 |
| Issue: | 1 |
| Page Number: | 4 |
| First Page: | 393 |
| Last Page: | 396 |
| DDC classes: | 570 Biowissenschaften, Biologie |
| Open access?: | Ja |
| Licence (German): |  Creative Commons - CC BY - Namensnennung 4.0 International |
