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Generation of an azide-modified extracellular matrix by adipose-derived stem cells using metabolic glycoengineering

  • Natural extracellular matrix (ECM) represents an ideal biomaterial for tissue engineering and regenerative medicine approaches. For further functionalization, there is a need for specific addressable functional groups within this biomaterial. Metabolic glycoengineering (MGE) provides a technique to incorporate modified monosaccharide derivatives into the ECM during their assembly, which was shown by us earlier for the production of a modified fibroblast-derived dermal ECM.

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Metadaten
Name:Nellinger, Svenja; Volz, Ann-Cathrin; Kluger, Petra
URN:urn:nbn:de:bsz:rt2-opus4-25648
DOI:https://doi.org/10.1515/cdbme-2019-0099
ISSN:2364-5504
Erschienen in:Current directions in biomedical engineering
Publisher:De Gruyter
Place of publication:Berlin
Document Type:Article
Language:English
Year of Publication:2019
Tag:adipose-derived stem cells; azide-modified; clickECM; extracellular matrix; metabolic glycoengineering
Volume:5
Issue:1
Pagenumber:4
First Page:393
Last Page:396
Dewey Decimal Classification:570 Biowissenschaften, Biologie
Open Access:Ja
Licence (German):License Logo  Open Access