Composite polymer/wax coatings as a corrosion barrier of bioresorbable magnesium coronary stents
- Magnesium and its alloys are suitable materials for biodegradable biomedical implants such as cardiovascular stents. Here we introduce an innovative composite polyelectrolyte multilayer/wax coating applied to commercial coronary Mg-based stents serving as a barrier layer effectively retarding corrosion. This hydrophobic coating, build by layer-by-layer technology, appeared very thin, smooth, homogeneous, strongly adherent and completely covering the surface of the Mg-stent. In-vitro degradation tests showed greater resistance to degradation of coated Mg-stents compared to uncoated and passivated ones. Cytocompatibility studies proved that Mg-stent coated with the composite coating was non-cytotoxic and improved fibroblast cell viability compared to the uncoated Mg-stent.
| Author of HS Reutlingen | Andreeva, Tonya; Walker, Oliver; Rudt, Alexander; Krastev, Rumen |
|---|---|
| URN: | urn:nbn:de:bsz:rt2-opus4-51110 |
| DOI: | https://doi.org/10.1016/j.heliyon.2024.e34025 |
| ISSN: | 2405-8440 |
| Published in: | Heliyon |
| Publisher: | Elsevier |
| Place of publication: | London |
| Document Type: | Journal article |
| Language: | English |
| Publication year: | 2024 |
| Tag: | Mg-based stents; composite coatings; corrosion resistance; in-vitro degradation; magnesium alloy |
| Volume: | 10 |
| Issue: | 13 |
| Page Number: | 13 |
| Article Number: | e34025 |
| DDC classes: | 540 Chemie |
| Open access?: | Ja |
| Licence (German): |  Creative Commons - CC BY-NC - Namensnennung - Nicht kommerziell 4.0 International |
