ECM-mimicking PEM films as a valuable tool for enhanced endothelial cell adhesion
- The creation of surfaces that mimic the structure and composition of the extracellular matrix (ECM) is a potentially attractive approach for the creation of biomaterials with cell-related applications. Here, ECM-mimicking surfaces were fabricated via layer-by-layer (LbL) assembly of poly (allylamine hydrochloride) (PAH) and poly (acrylic acid) (PAA)., with fibrinogen (FNG)., a common ECM protein. Analysis of cell viability., cell morphology., and immunofluorescence of focal adhesion formation of HUVECs adhered to PAH - ended PEMs and FNG coating revealed improved cell adhesion and spreading.
| Author of HS Reutlingen | Krastev, Rumen; Andreeva, Tonya |
|---|---|
| DOI: | https://doi.org/10.1109/3M-NANO65639.2025.11261109 |
| Published in: | 2025 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) ; July 28-August 1, 2025, Changchun, China, conference proceedings |
| Publisher: | IEEE |
| Place of publication: | New York |
| Document Type: | Conference proceeding |
| Language: | English |
| Publication year: | 2025 |
| Page Number: | 4 |
| First Page: | 147 |
| Last Page: | 150 |
| DDC classes: | 570 Biowissenschaften, Biologie |
| Open access?: | Nein |
| Licence (German): |  In Copyright - Urheberrechtlich geschützt |
