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Evaluation of antibacterial properties of polyelectrolyte multilayer coatings by norm tests

  • Medical implants play a central role in modern medicine and both, naturally derived and synthetic materials have been explored as biomaterials for such devices. However, when implanted into living tissue, most materials initiate a host response. In addition, implants often cause bacterial infections leading to complications. Polyelectrolyte multilayer (PEM) coatings can be used for functionalization of medical implants improving the implant integration and reducing foreign body reactions. Some PEMs are also known to show antibacterial properties. We developed a PEM coating suggesting that it can decrease the risk of bacterial infections occurring after implantation while being highly biocompatible. We applied two different standard tests for evaluating the PEM’s antibacterial properties, the ISO norm (ISO 22196) and one ASTM norm (ASTM E2180) test. We found a reduction of bacterial growth on the PEM but to a different degree depending on the testing method. This result demonstrates the need for defining proper method to evaluate antibacterial properties of surface coatings.

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Metadaten
Author of HS ReutlingenDjanklich, Leyla; Andreeva, Tonya; Krastev, Rumen; Kemkemer, Ralf
URN:urn:nbn:de:bsz:rt2-opus4-30100
DOI:https://doi.org/10.1515/cdbme-2020-3122
ISSN:2364-5504
Erschienen in:Current directions in biomedical engineering
Publisher:De Gruyter
Place of publication:Berlin
Document Type:Article
Language:English
Year of Publication:2020
Tag:antibacterial coating; implants; norm tests; polyelectrolyte multilayer coatings
Volume:6
Issue:3
Page Number:4
First Page:1
Last Page:4
Article Number:20203122
DDC classes:570 Biowissenschaften, Biologie
Open Access?:Ja
Licence (German):License Logo  Creative Commons - CC BY - Namensnennung 4.0 International