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Elastic and inelastic light scattering spectroscopy and its possible use for label-free brain tumor typing

  • This paper presents an approach for label-free brain tumor tissue typing. For this application, our dual modality microspectroscopy system combines inelastic Raman scattering spectroscopy and Mie elastic light scattering spectroscopy. The system enables marker-free biomedical diagnostics and records both the chemical and morphologic changes of tissues on a cellular and subcellular level. The system setup is described and the suitability for measuring morphologic features is investigated.

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Metadaten
Name:Ostertag, Edwin; Stefanakis, Mona; Rebner, Karsten
DOI:https://doi.org/10.1007/s00216-017-0614-1
ISSN:1618-2642
eISSN:1618-2650
Erschienen in:Analytical and bioanalytical chemistry
Publisher:Springer
Place of publication:Berlin ; Heidelberg
Document Type:Article
Language:English
Year of Publication:2017
Tag:Mie elastic light scattering spectroscopy; Raman inelastic light scattering spectroscopy; bimodal; brain tumor typing; label-free; multi-spectroscopy
Volume:409
Issue:28
Pagenumber:11
First Page:6613
Last Page:6623
Dewey Decimal Classification:540 Chemie
Open Access:Nein
Licence (German):License Logo  Lizenzbedingungen Springer