Calibration and validation of a MCC/IMS prototype for exhaled propofol online measurement
- Propofol is a commonly used intravenous general anesthetic. Multi-capillary column (MCC) coupled ion-mobility spectrometry (IMS) can be used to quantify exhaled propofol, and thus estimate plasma drug concentration. Here, we present results of the calibration and analytical validation of a MCC/IMS pre-market prototype for propofol quantification in exhaled air.
| Author of HS Reutlingen | Walter, Larissa; Baumbach, Jörg Ingo |
|---|---|
| DOI: | https://doi.org/10.1016/j.jpba.2017.06.052 |
| ISSN: | 0731-7085 |
| eISSN: | 1873-264X |
| Erschienen in: | Journal of pharmaceutical and biomedical analysis : the official analytical journal of the American Association of Pharmaceutical Scientists |
| Publisher: | Elsevier |
| Place of publication: | New York, NY |
| Document Type: | Journal article |
| Language: | English |
| Publication year: | 2017 |
| Tag: | Propofol; anesthesia; breath analysis; calibration; drug monitoring; multi-capillary column coupled ion-mobility spectrometer |
| Volume: | 145 |
| Page Number: | 5 |
| First Page: | 293 |
| Last Page: | 297 |
| DDC classes: | 610 Medizin, Gesundheit |
| Open access?: | Nein |
| Licence (German): |  In Copyright - Urheberrechtlich geschützt |
