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Purpose: Human breath analysis is proposed with increasing frequency as a useful tool in clinical application. We performed this study to find the characteristic volatile organic compounds (VOCs) in the exhaled breath of patients with idiopathic pulmonary fibrosis (IPF) for discrimination from healthy subjects. Methods: VOCs in the exhaled breath of 40 IPF patients and 55 healthy controls were measured using a multi-capillary column and ion mobility spectrometer. The patients were examined by pulmonary function tests, blood gas analysis, and serum biomarkers of interstitial pneumonia. Results: We detected 85 VOC peaks in the exhaled breath of IPF patients and controls. IPF patients showed 5 significant VOC peaks; p-cymene, acetoin, isoprene, ethylbenzene, and an unknown compound. The VOC peak of p-cymene was significantly lower (p < 0.001), while the VOC peaks of acetoin, isoprene, ethylbenzene, and the unknown compound were significantly higher (p < 0.001 for all) compared with the peaks of controls. Comparing VOC peaks with clinical parameters, negative correlations with VC (r =−0.393, p = 0.013), %VC (r =−0.569, p < 0.001), FVC (r = −0.440, p = 0.004), %FVC (r =−0.539, p < 0.001), DLco (r =−0.394, p = 0.018), and %DLco (r =−0.413, p = 0.008) and a positive correlation with KL-6 (r = 0.432, p = 0.005) were found for p-cymene. Conclusion: We found characteristic 5 VOCs in the exhaled breath of IPF patients. Among them, the VOC peaks of p-cymene were related to the clinical parameters of IPF. These VOCs may be useful biomarkers of IPF.
In times of dynamic markets, enterprises have to be agile to be able to quickly react to market influences. Due to the increasing digitization of products, the enterprise IT often is affected when business models change. Enterprise Architecture Management (EAM) targets a holistic view of the enterprise’ IT and their relations to the business. However, Enterprise Architectures (EA) are complex structures consisting of many layers, artifacts and relationships between them. Thus, analyzing EA is a very complex task for stakeholders. Visualizations are common vehicles to support analysis. However, in practice visualization capabilities lack flexibility and interactivity. A solution to improve the support of stakeholders in analyzing EAs might be the application of visual analytics. Starting from a systematic literature review, this article investigates the features of visual analytics relevant for the context of EAM.
The purpose of this paper is to determine the relevance of social media for luxury brand management. It employs both a multi-methodological approach: After analyzing the online performance of the three luxury brands Burberry, Louis Vuitton and Gucci, the empirical research includes a survey as well as an eye tracking test executed with Tobii Studio. The findings reveal that online and social media have given luxury fashion businesses the opportunity to establish a sustainable interaction with their customers and distinguish themselves from the competition. Still, the online business holds many challenges for luxury companies to overcome. This paper gives instructions as to how social media can be effectively incorporated into a luxury company.
The purpose of this paper is to study the recycling form of reusing second hand clothing from a conventional fashion brand’s perspective. It should clarify which measures and activities a fashion company needs to integrate in its value chain in order to offer branded second hand merchandise in a self-operated store. The research paper relies on a desk-based research and aims to illustrate the topic by means of a descriptive approach, processing the existing literature. Key findings demonstrate that fashion brands need to integrate complete lifecycle strategies, sustainability communication, and reverse logistics structures, like take-back schemes, for offering second hand clothing. The main limitations evolve from the research design. Further, empirical evidences need to be conducted for a more fundamental understanding of the new business model.
The second hand concept indicates a growing trend in clothing recently, leading to growing numbers of second hand shops and developments of new second hand retail forms. This paper concentrates on the current second hand market for fashion products and presents the different motives toward second hand consumption as well as alternative consumption channels for second hand products. The findings of the paper are founded on literature research of academic articles and case studies. Results show that there is a high potential for the second hand market due to the increasing interest of consumers in buying second hand products. The paper concentrates on the second hand market for fashion products in the western society. This means that there was no research on second hand products for disadvantaged people in poor countries. Furthermore, the paper focuses the formal second hand retail channels to see what is already on the market.
This study focuses on the different roles of social media for the promotion of a sustainable lifestyle, behaviour and consumption, especially with regard to the typically non-ethical fashion industry. Research findings include eight roles of social media influencing a sustainable consumption contrary to prior research naming one to five impacts. Results show that social media educates and engages the young and ethically interested target group besides increasing supply chain transparency and brand or theme awareness. Furthermore, social media provides a platform for organisations’ relationship management and social interaction since users get empowered to share experiences which leads to a higher level of trust.
The purpose of this paper is to highlight potentials and limitations of the prosumer concept in fashion retail. The paper illustrates the evolution of prosumption and in which directions the concept is being developed. The primary research is based on a literature review containing different sources of academic and non-academic references. Findings suggest that the prosumer concept is no new phenomenon. Recently, it has moved into the focus of companies that have noted that it is efficient when engaging with customers in order to strengthen their brand loyalty. An increasing number of companies offer innovative business models that underlie the concept. However, lately smart prosuming machines are changing the objectives of the concept. Even if the prosumer concept exists since many years and scholars investigate its potentials continuously, it is the fashion industry that has been researched comparatively little up to now.
Digitization transforms business process models and processes in many enterprises. However, many of them need guidance, how digitization is impacting the design of their information systems. Therefore, this paper investigates the influence of digitization on information system design. We apply a two-phase research method applying a literature review and an exploratory case study. The case study took place in the IT service provider of a large insurance enterprise. The study’s results suggest that a number of areas of information system design are affected, such as architecture, processes, data and services.
This article provides a general overview of the most promising candidates of bio based materials and deals with the most important issues when it comes to their incorporation into PF resins. Due to their abundance on Earth, much knowledge of lignin-based materials has already been gained and uses of lignin in PF resins have been studied for many decades. Other natural polyphenols that are less frequently considered for impregnation are covered as well, as they do also possess some potential for PF substitution.