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A methodology for designing planar spiral antennas with a feeding network embedded within a dielectric is presented. To avoid a purely academic work which may not be manufactured with available standard technologies, the approach takes into account manufacturing process requirements by choice of used materials in the simulation. General design rules are provided. They encompass amongst others, selection criteria for dielectric material, aspects to consider when sketching the radiating element design, as well as those for the implementation of the feeding network. A rule of thumb, which maybe helpful in the determination of the antenna supporting substrate’s height, has been found. The appeal of the method resides in the fact that it eases up the design process and helps to minimize errors, saving time and money. The approach also enables the design of a compact and small-size spiral antenna as antenna-in-package (AiP), and provides the opportunity to assemble the antenna with other RF components/systems on the same layer stack or on the same integration platform.
In recent years, machine learning algorithms have made a huge development in performance and applicability in industry and especially maintenance. Their application enables predictive maintenance and thus offers efficiency increases. However, a successful implementation of such solutions still requires high effort in data preparation to obtain the right information, interdisciplinarity in teams as well as a good communication to employees. Here, small and medium sized enterprises (SME) often lack in experience, competence and capacity. This paper presents a systematic and practice-oriented method for an implementation of machine learning solutions for predictive maintenance in SME, which has already been validated.
Heat pumps are a vital element for reaching the greenhouse gas (GHG) reduction targets in the heating sector, but their system integration requires smart control approaches. In this paper, we first offer a comprehensive literature review and definition of the term control for the described context. Additionally, we present a control approach, which consists of an optimal scheduling module coupled with a detailed energy system simulation module. The aim of this integrated two part control approach is to improve the performance of an energy system equipped with a heat pump, while recognizing the technical boundaries of the energy system in full detail. By applying this control to a typical family household situation, we illustrate that this integrated approach results in a more realistic heat pump operation and thus a more realistic assessment of the control performance, while still achieving lower operational costs.
This paper presents a novel emulation concept for the test of smart contracts and Distributed Ledger Technologies (DLT) in distribute control or energy economy tasks and use cases. The concept uses state of the art behavioral modeling tools such as Matlab Simulink but presents a possible way to solve the shortfall of Simulink in communicating to DLT-Nodes directly. This is solved through a middleware solution. After this, an example used in verifying the test bed is presented and the target demonstration object is described. Finally, the possible expansion of the system is discussed and presented.
Cardiovascular diseases are directly or indirectly responsible for up to 38.5% of all deaths in Germany and thus represent the most frequent cause of death. At present, heart diseases are mainly discovered by chance during routine visits to the doctor or when acute symptoms occur. However, there is no practical method to proactively detect diseases or abnormalities of the heart in the daily environment and to take preventive measures for the person concerned. Long-term ECG devices, as currently used by physicians, are simply too expensive, impractical, and not widely available for everyday use. This work aims to develop an ECG device suitable for everyday use that can be worn directly on the body. For this purpose, an already existing hardware platform will be analyzed, and the corresponding potential for improvement will be identified. A precise picture of the existing data quality is obtained by metrological examination, and corresponding requirements are defined. Based on these identified optimization potentials, a new ECG device is developed. The revised ECG device is characterized by a high integration density and combines all components directly on one board except the battery and the ECG electrodes. The compact design allows the device to be attached directly to the chest. An integrated microcontroller allows digital signal processing without the need for an additional computer. Central features of the evaluation are a peak detection for detecting R-peaks and a calculation of the current heart rate based on the RR interval. To ensure the validity of the detected R-peaks, a model of the anatomical conditions is used. Thus, unrealistic RR-intervals can be excluded. The wireless interface allows continuous transmission of the calculated heart rate. Following the development of hardware and software, the results are verified, and appropriate conclusions about the data quality are drawn. As a result, a very compact and wearable ECG device with different wireless technologies, data storage, and evaluation of RR intervals was developed. Some tests yelled runtimes up to 24 hours with wireless Lan activated and streaming.
The chemical synthesis of polysiloxanes from monomeric starting materials involves a series of hydrolysis, condensation and modification reactions with complex monomeric and oligomeric reaction mixtures. Real-time monitoring and precise process control of the synthesis process is of great importance to ensure reproducible intermediates and products and can readily be performed by optical spectroscopy. In chemical reactions involving rapid and simultaneous functional group transformations and complex reaction mixtures, however, the spectroscopic signals are often ambiguous due to overlapping bands, shifting peaks and changing baselines. The univariate analysis of individual absorbance signals is hence often only of limited use. In contrast, batch modelling based on the multivariate analysis of the time course of principal components (PCs) derived from the reaction spectra provides a more efficient tool for real time monitoring. In batch modelling, not only single absorbance bands are used but information over a broad range of wavelengths is extracted from the evolving spectral fingerprints and used for analysis. Thereby, process control can be based on numerous chemical and morphological changes taking place during synthesis. “Bad” (or abnormal) batches can quickly be distinguished from “normal” ones by comparing the respective reaction trajectories in real time. In this work, FTIR spectroscopy was combined with multivariate data analysis for the in-line process characterization and batch modelling of polysiloxane formation. The synthesis was conducted under different starting conditions using various reactant concentrations. The complex spectral information was evaluated using chemometrics (principal component analysis, PCA). Specific spectral features at different stages of the reaction were assigned to the corresponding reaction steps. Reaction trajectories were derived based on batch modelling using a wide range of wavelengths. Subsequently, complexity was reduced again to the most relevant absorbance signals in order to derive a concept for a low-cost process spectroscopic set-up which could be used for real-time process monitoring and reaction control.
Documentation of clinical processes, especially in the perioperative are, is a base requirement for quality of service. Nonetheless, the documentation is a burden for the medical staff since it distracts from the clinical core process. An intuitive and user-friendly documentation system could increase documentation quality and reduce documentation workload. The optimal system solution would know what happened and the person documenting the step would need a single “confirm” button. In many cases, such a linear flow of activities is given as long as only one profession (e.g. anaestesiology, scrub nurse) is considered, but even in such cases, there might be derivations from the linear process flow and further interaction is required.
Estimating molar solubility from the Hildebrand-Scott relation employing Hansen solubility parameters (HSP) is widely presumed a valid semi quantitative approach. To test this presumption and to determine quantitatively the inherent accuracy of such a solubility prognosis, l-ascorbic acid (LAA) was treated as an example of a commercially important solute. Analytical calculus and Monte Carlo (MC) simulation were performed for 20 common solvents with total HSP ranging from 14.5 to 33.0 (MPa)0.5 utilizing validated material data. It was found that, due to the uncertainty of the material data used in the calculations, the solubility prediction had a large scattering and, thus, a low precision.
Tissue constructs of physiologically relevant scale require a vascular system to maintain cell viability. However, in vitro vascularization of engineered tissues is still a major challenge. Successful approaches are based on a feeder layer (FL) to support vascularization. Here, we investigated whether the supporting effect on the self‐assembled formation of prevascular‐like structures by microvascular endothelial cells (mvECs) originates from the FL itself or from its extracellular matrix (ECM). Therefore, we compared the influence of ECM, either derived from adipose‐derived stem cells (ASCs) or adipogenically differentiated ASCs, with the classical cell‐based FL. All cell‐derived ECM (cdECM) substrates enabled mvEC growth with high viability. Prevascular‐like structures were visualized by immunofluorescence staining of endothelial surface protein CD31 and could be observed on all cdECM and FL substrates but not on control substrate collagen I. On adipogenically differentiated ECM, longer and higher branched structures could be found compared with stem cell cdECM. An increased concentration of proangiogenic factors was found in cdECM substrates and FL approaches compared with controls. Finally, the expression of proteins associated with tube formation (E‐selectin and thrombomodulin) was confirmed. These results highlight cdECM as promising biomaterial for adipose tissue engineering by inducing the spontaneous formation of prevascular‐like structures by mvECs.
Bone tissue is highly vascularized. The crosstalk of vascular and osteogenic cells is not only responsible for the formation of the strongly divergent tissue types but also for their physiological maintenance and repair. Extrusion-based bioprinting presents a promising fabrication method for bone replacement. It allows for the production of large-volume constructs, which can be tailored to individual tissue defect geometries. In this study, we used the all-gelatin-based toolbox of methacryl-modified gelatin (GM), non-modified gelatin (G) and acetylated GM (GMA) to tailor both the properties of the bioink towards improved printability, and the properties of the crosslinked hydrogel towards enhanced support of vascular network formation by simple blending. The vasculogenic behavior of human dermal microvascular endothelial cells (HDMECs) and human adipose-derived stem cells (ASCs) was evaluated in the different hydrogel formulations for 14 days. Co-culture constructs including a vascular component and an osteogenic component (i.e. a bone bioink based on GM, hydroxyapatite and ASCs) were fabricated via extrusion-based bioprinting. Bioprinted co-culture constructs exhibited functional tissue-specific cells whose interplay positively affected the formation and maintenance of vascular-like structures. The setup further enabled the deposition of bone matrix associated proteins like collagen type I, fibronectin and alkaline phosphatase within the 30-day culture.
With significant advancements in digital technologies, firms find themselves competing in an increasingly dynamic business environment. It is of paramount importance that organizations undertake proper governance mechanisms with respect to their business and IT strategies. Therefore, IT governance (ITG) has become an important factor for firm performance. In recent years, agility has evolved as a core concept for governance, especially in the area of software development. However, the impact of agility on ITG and firm performance has not been analyzed by the broad scientific community. This paper focuses on the question, how the concept of agility affects the ITG–firm performance relationship. The conceptual model for this question was tested by a quantitative research process with 400 executives responding to a standardized survey. Findings show that the adoption of agile principles, values, and best practices to the context of ITG leads to meaningful results for governance, business/IT alignment, and firm performance.
In recent years, the cloud has become an attractive execution environment for parallel applications, which introduces novel opportunities for versatile optimizations. Particularly promising in this context is the elasticity characteristic of cloud environments. While elasticity is well established for client-server applications, it is a fundamentally new concept for parallel applications. However, existing elasticity mechanisms for client-server applications can be applied to parallel applications only to a limited extent. Efficient exploitation of elasticity for parallel applications requires novel mechanisms that take into account the particular runtime characteristics and resource requirements of this application type. To tackle this issue, we propose an elasticity description language. This language facilitates users to define elasticity policies, which specify the elasticity behavior at both cloud infrastructure level and application level. Elasticity at the application level is supported by an adequate programming and execution model, as well as abstractions that comply with the dynamic availability of resources. We present the underlying concepts and mechanisms, as well as the architecture and a prototypical implementation. Furthermore, we illustrate the capabilities of our approach through real-world scenarios.
The purpose of this paper is to give an overview about the links between fashion businesses and film from a fashion business perspective. It focuses on the idea that digitalization brought much more film use for the fashion industry and that this development has just begun and not ended. This change finally also has an intense impact on the fashion industry, as fashion companies nowadays are content producers with films, too. The resulting closer connection with viewers via social media exposes fashion companies, gives on the other hand new influence potential to the fashion system. An in-depth future research about the fashion and film system is therefore required to develop answers for the current situation. This article should be interpreted more as a personal viewpoint of the author to this topic rather than a research paper based on the usual methodological criteria.
The supply of customer-specific products is leading to the increasing technical complexity of machines and plants in the manufacturing process. In order to ensure the availability of the machines and plants, maintenance is considered as an essential key. The application of cyber-physical systems enables the complexity to be mastered by improving the availability of information, implementing predictive maintenance strategies and the provision of all relevant information in real-time. The present research project deals with the development of a cost-effective and retrofittable smart maintenance system for the application of ultraviolet (UV) lamps. UV lamps are used in a variety of applications such as curing of materials and water disinfection, where UV lamps are still used instead of UV LED due to their higher effectiveness. The smart maintenance system enables continuous condition monitoring of the UV lamp through the integration of sensors. The data obtained are compared with data from existing lifetime models of UV lamps to provide information about the remaining useful lifetime of the UV lamp. This ensures needs-based maintenance measures and more efficient use of UV lamps. Furthermore, it is important to have accurate information on the remaining useful lifetime of a UV lamp, as the unplanned breakdown of a UV lamp can have far-reaching consequences. The key element is the functional model of the envisioned cyber-physical system, describing the dependencies between the sensors and actuator, the condition monitoring system as well as the IoT platform. Based on the requirements developed and the functional model, the necessary hardware and software are selected. Finally, the system is developed and retrofitted to a simulated curing process of a 3D printer to validate its functional capability. The developed system leads to improved information availability of the condition of UV lamps, predictive maintenance measures and context-related provision of information.
Today, digitalization is firmly anchored in society and business. It is also recognized to have significant impact on the retailing sector. The in-store display of moving images has so far, however, gained little attention by researchers. The aim of this research is to provide a first estimation on the current state of moving images distribution in stationary retail stores. A store check was the basis for analysis and evaluation. In sum, 152 stores were analyzed in Stuttgart, Germany. Out of 152 observed stores, 62 stores showed 177 moving images. Detailed analyses about content, mood, color and the actors of motion pictures showed that all aspects are very well harmonized with the target group of the store. The chapter provides a basic estimation of the in-store diffusion of moving images. Thereby, avenues for further research are opened up.
This work is a study about a comparison of survey tools and it should help developers in selecting a suited tool for application in an AAL environment. The first step was to identify the basic required functionality of the survey tools used for AAL technologies and to compare these tools by their functionality and assignments. The comparative study was derived from the data obtained, previous literature studies and further technical data. A list of requirements was stated and ordered in terms of relevance to the target application domain. With the help of an integrated assessment method, the calculation of a generalized estimate value was performed and the result is explained. Finally, the planned application of this tool in a running project is explained.
Steady state efficiency optimization techniques for induction motors are state of the art and various methods have already been developed. This paper provides new insights in the efficiency optimized operation in dynamic regime. The paper proposes an anticipative flux modification in order to decrease losses during torque and speed transients. These trajectories are analyzed based on a numerical study for different motors. Measurement results for one motor are given as well.
Development work within an experimental environment, in which certain properties are investigated and optimized, requires many test runs and is therefore often associated with long execution times, costs and risks. This can affect product, material and technology development in industry and research. New digital driver technologies offer the possibility to automate complex manual work steps in a cost-effective way, to increase the relevance of the results and to accelerate the processes many times over. In this context, this article presents a low-cost, modular and open-source machine vision system for test execution and evaluates it on the basis of a real industrial application. For this purpose a methodology for the automated execution of the load intervals, the process documentation and for the evaluation of the generated data by means of machine learning to classify wear levels. The software and the mechanical structure are designed to be adaptable to different conditions, components and for a variety of tasks in industry and research. The mechanical structure is required for tracking the test object and represents a motion platform with independent positioning by machine vision operators or machine learning. An evaluation of the state of the test object is performed by the transfer learning after the initial documentation run. The manual procedure for classifying the visually recorded data on the state of the test object is described for the training material. This leads to an increased resource efficiency on the material as well as on the personnel side since on the one hand the significance of the tests performed is increased by the continuous documentation and on the other hand the responsible experts can be assigned time efficiently. The presence and know-how of the experts are therefore only required for defined and decisive events during the execution of the experiments. Furthermore, the generated data are suitable for later use as an additional source of data for predictive maintenance of the developed object.
Our paper gives first answers on a fundamental question: how can the design of architectures of intelligent digital systems and services be accomplished methodologically? Intelligent systems and services are the goals of many current digitalization efforts today and part of massive digital transformation efforts based on digital technologies. Digital systems and services are the foundation of digital platforms and ecosystems. Digtalization disrupts existing businesses, technologies, and economies and promotes the architecture of open environments. This has a strong impact on new value-added opportunities and the development of intelligent digital systems and services. Digital technologies such as artificial intelligence, the Internet of Things, services computing, cloud computing, big data with analytics, mobile systems, and social enterprise networks systems are important enablers of digitalization. The current publication presents our research on the architecture of intelligent digital ecosystems and products and services influenced by the service-dominant logic. We present original methodological extensions and a new reference model for digital architectures with an integral service and value perspective to model intelligent systems and services that effectively align digital strategies and architectures with artificial intelligence as main elements to support intelligent digitalization.
Airports largely outgrew their sole purpose of simply being travel hubs and by connecting millions of passengers to their destinations each year on an international scale, they have become increasingly interesting for business and related marketing opportunities. In fact, passengers are easily segmented and can be reached effectively throughout specific airport areas, making some areas more suitable for advertising than others. Emotional states, roaming time and the freedom to move vastly, influence how much information passengers are able to absorb from their direct surroundings. Finally our research shows that some areas are more suitable than others. Therefore a careful selection of airport locations for communication will be key to secure the impact and improve the effectiveness of communication measures. With these insights, advertisers can deliberately choose the areas that are most effective for displaying their ads.
The promise of the EVs is twofold. First, rejuvenating a transport sector that still heavily depends on fossil fuels and second, integrating intermittent renewable energies into the power mix. However, it is still not clear how electricity networks will cope with the predicted increase in EVs and their charging demand, especially in combination with conventional energy demand. This paper proposes a methodology which allows to predict the impact of EV charging behavior on the electricity grid. Moreover, this model simulates the driving and charging behavior of heterogeneous EV drivers which differ in their mobility pattern, decision-making heuristics and charging strategies. The simulations show that uncoordinated charging results in charging load clustering. In contrast, decentralized coordination allows to fill the valleys of the conventional load curve and to integrate EVs without the need of a costly expansion of the electricity grid.
Based on a survey among customers of seven German municipal utilities, we estimate two regression models to identify the most prospective customer segments and their preferences and motivations for participating in peer-to-peer (P2P) electricity trading and develop implications for decision-makers in the energy sector and policy-makers for this currently relatively unknown product. Our results show a large general openness of private households towards P2P electricity trading, which is also the main predictor of respondents' intention to participate. It is mainly influenced by individuals’ environmental attitude, technical interest, and independence aspiration. Respondents with the highest willingness to participate in P2P electricity trading are mainly motivated by the ability to share electricity, and to a lesser extent by economic reasons. They also have stronger preferences for innovative pricing schemes (service bundles, time-of-use tariffs). Differences between individuals can be observed depending on their current ownership (prosumers) or installation probability of a microgeneration unit (consumers, planners). Rather than current prosumers, especially planners willing to install microgeneration in the foreseeable future are considered to be the most promising target group for P2P electricity trading. Finally, our results indicate that P2P electricity trading could be a promising niche option in the German energy transition.
Automatic anode rod inspection in aluminum smelters using deep-learning techniques: a case study
(2020)
Automatic fault detection using machine learning has become an exciting and promising area of research. This because it accurate and timely way to manage and classify with minimal human effort. In the computer vision community, deep-learning methods have become the most suitable approaches for this task. Anodes are large carbon blocks that are used to conduct electricity during the aluminum reduction process. The most basic function of anode rod inspection is to prevent a situation where the anode rod will not fit into the stub-holes of a new anode. It would be the case for a rod containing either severe toe-in, missing stubs, or a retained thimble on one or more stubs. In this work, to improve the accuracy of shape defect inspection for an anode rod, we use the Fast Region-based Convolutional Network method (Fast R-CNN), model. To train the detection model, we collect an image dataset composed of multi-class of anode rod defects with annotated labels. Our model is trained using a small number of samples, an essential requirement in the industry where the number of available defective samples is limited. It can simultaneously detect multi-class of defects of the anode rod in nearly real-time.
Automatic classification of rotating machinery defects using Machine Learning (ML) algorithms
(2020)
Electric machines and motors have been the subject of enormous development. New concepts in design and control allow expanding their applications in different fields. The vast amount of data have been collected almost in any domain of interest. They can be static; that is to say, they represent real-world processes at a fixed point of time. Vibration analysis and vibration monitoring, including how to detect and monitor anomalies in vibration data are widely used techniques for predictive maintenance in high-speed rotating machines. However, accurately identifying the presence of a bearing fault can be challenging in practice, especially when the failure is still at its incipient stage, and the signal-to-noise ratio of the monitored signal is small. The main objective of this work is to design a system that will analyze the vibration signals of a rotating machine, based on recorded data from sensors, in the time/frequency domain. As a consequence of such substantial interest, there has been a dramatic increase of interest in applying Machine Learning (ML) algorithms to this task. An ML system will be used to classify and detect abnormal behavior and recognize the different levels of machine operation modes. The proposed solution can be deployed as predictive maintenance for Industry 4.0.
Checklists are a valuable tool to ensure process quality and quality of care. To ensure proper integration in clinical processes, it would be desirable to generate checklists directly from formal process descriptions. Those checklists could also be used for user interaction in context-aware surgical assist systems. We built a tool to automatically convert Business Process Model and Notation (BPMN) process models to checklists displayed as HTML websites. Gateways representing decisions are mapped to checklist items that trigger dynamic content loading based on the placed checkmark. The usability of the resulting system was positively evaluated regarding comprehensibility and end-user friendliness.
In recent years, the development and application of decellularized extracellular matrices (ECMs) for use as biomaterials have grown rapidly. These cell-derived matrices (CDMs) represent highly bioactive and biocompatible materials consisting of a complex assembly of biomolecules. Even though CDMs mimic the natural microenvironment of cells in vivo very closely, they still lack specifically addressable functional groups, which are often required to tailor a biomaterial functionality by bioconjugation. To overcome this limitation, metabolic glycoengineering has emerged as a powerful tool to equip CDMs with chemical groups such as azides. These small chemical handles are known for their ability to undergo bioorthogonal click reactions, which represent a desirable reaction type for bioconjugation. However, ECM insolubility makes its processing very challenging. In this contribution, we isolated both the unmodified ECM and azide-modified clickECM by osmotic lysis. In a first step, these matrices were concentrated to remove excessive water from the decellularization step. Next, the hydrogel-like ECM and clickECM films were mechanically fragmentized, resulting in easy to pipette suspensions with fragment sizes ranging from 7.62 to 31.29 μm (as indicated by the mean d90 and d10 values). The biomolecular composition was not impaired as proven by immunohistochemistry. The suspensions were used for the reproducible generation of surface coatings, which proved to be homogeneous in terms of ECM fragment sizes and coating thicknesses (the mean coating thickness was found to be 33.2 ± 7.3 μm). Furthermore, they were stable against fluid-mechanical abrasion in a laminar flow cell. When primary human fibroblasts were cultured on the coated substrates, an increased bioactivity was observed. By conjugating the azides within the clickECM coatings with alkyne-coupled biotin molecules, a bioconjugation platform was obtained, where the biotin–streptavidin interaction could be used. Its applicability was demonstrated by equipping the bioactive clickECM coatings with horseradish peroxidase as a model enzyme.
This article adopts a qualitative comparative causal mapping approach to extend knowledge of the interrelated barriers to public entrepreneurship and the outcomes of such entrepreneurship. The results highlight marked differences between the sales segment and the distribution grid segment of German public enterprises that should prompt a refined perspective on public entrepreneurship. Notably, besides intra-organizational barriers and those interfering from the external environment, results also show that a public enterprise’s supervisory board can hinder its progress. This study thus contributes to recent discussion on governance and entrepreneurship by revealing a feature that could distinguish public from private enterprises.
To remain relevant and mitigate disruption, traditional companies have to engage in multiple fast-paced experiments in digital offerings: revenue-generating solutions that leverage digital technologies to address customer needs. After launching several digital offering initiatives, reinsurance giant Munich Re noticed that many experienced similar challenges. This briefing describes how Munich Re addressed these common challenges by building a foundation for experimenting more systematically and successfully with digital offerings. The foundation has enabled Munich Re to become a serial innovator of digital offerings.
Whether diversity enhances or impedes team creativity remains an issue of scholarly debate. Explanations of this ambiguity often lie in how diversity is both operationalized and measured. Eschewing the popular approach of using differences in objective criteria to signal diversity, a deep-level approach that focuses on differences in personal values is taken in this study. Value diversity is measured in the two forms of variety and separation and their associations with team creativity are explored. The investigation is augmented by considering the mediating role of team communication in these associations. The analysis was conducted on a sample of 98 teams, using both subjective and objective measures. The findings reveal that when considering value diversity in terms of variety, there is a positive association between diversity and team creativity. However, when the separation dimension of value diversity is considered, a negative association between diversity and team creativity is identified. Complex pathways pertaining to the role of communication within these relationships are also uncovered. In moving beyond rudimentary categories and measurement of diversity, this study further elucidates the complexity of the diversity–creativity relationship. Conclusions are drawn and implications for further research and managerial practice are derived.
In previous studies, we used a method for detecting stress that was based exclusively on heart rate and ECG for differentiation between such situations as mental stress, physical activity, relaxation, and rest. As a response of the heart to these situations, we observed different behavior in the Root Mean Square of the Successive differences heartbeats (RMSSD). This study aims to analyze Virtual Reality via a virtual reality headset as an effective stressor for future works. The value of the Root Mean Square of the Successive Differences is an important marker for the parasympathetic effector on the heart and can provide information about stress. For these measurements, the RR interval was collected using a breast belt. In these studies, we can observe the Root Mean Square of the successive differences heartbeats. Additional sensors for the analysis were not used. We conducted experiments with ten subjects that had to drive a simulator for 25 minutes using monitors and 25 minutes using virtual reality headset. Before starting and after finishing each simulation, the subjects had to complete a survey in which they had to describe their mental state. The experiment results show that driving using virtual reality headset has some influence on the heart rate and RMSSD, but it does not significantly increase the stress of driving.
The extracellular matrix (ECM) naturally surrounds cells in humans, and therefore represents the ideal biomaterial for tissue engineering. ECM from different tissues exhibit different composition and physical characteristics. Thus, ECM provides not only physical support but also contains crucial biochemical signals that influence cell adhesion, morphology, proliferation and differentiation. Next to native ECM from mature tissue, ECM can also be obtained from the in vitro culture of cells. In this study, we aimed to highlight the supporting effect of cell-derived- ECM (cdECM) on adipogenic differentiation. ASCs were seeded on top of cdECM from ASCs (scdECM) or pre-adipocytes (acdECM). The impact of ECM on cellular activity was determined by LDH assay, WST I assay and BrdU assay. A supporting effect of cdECM substrates on adipogenic differentiation was determined by oil red O staining and subsequent quantification. Results revealed no effect of cdECM substrates on cellular activity. Regarding adipogenic differentiation a supporting effect of cdECM substrates was obtained compared to control. With these results, we confirm cdECM as a promising biomaterial for adipose tissue engineering.
The connection of fashion and film seems symbiotic at first sight and they influence each other. There exist differences, including a different understanding of clothing by costume designers and fashion businesses. This article focuses on two successful movies „The Hunger Games“ and „The Great Gatsby“ in order to explore the role of film in fashion and vice versa. The findings suggest, that there are various collections in the fashion world, based on both movies. Therefore, movies indeed have an influence on the development of seasonal fashion. However, this connection is not natural, but rather artificially created by both industries. Through nowadays organized co-operation, the lines between costume designers and fashion designers get blurred. Furthermore, today fashion doesn’t trickle down to an audience naturally, but promoted using the film and its broad reach.
While many maintainability metrics have been explicitly designed for service-based systems, tool-supported approaches to automatically collect these metrics are lacking. Especially in the context of microservices, decentralization and technological heterogeneity may pose challenges for static analysis. We therefore propose the modular and extensible RAMA approach (RESTful API Metric Analyzer) to calculate such metrics from machine-readable interface descriptions of RESTful services. We also provide prototypical tool support, the RAMA CLI, which currently parses the formats OpenAPI, RAML, and WADL and calculates 10 structural service-based metrics proposed in scientific literature. To make RAMA measurement results more actionable, we additionally designed a repeatable benchmark for quartile-based threshold ranges (green, yellow, orange, red). In an exemplary run, we derived thresholds for all RAMA CLI metrics from the interface descriptions of 1,737 publicly available RESTful APIs. Researchers and practitioners can use RAMA to evaluate the maintainability of RESTful services or to support the empirical evaluation of new service interface metrics.
Detecting semantic similarities between sentences is still a challenge today due to the ambiguity of natural languages. In this work, we propose a simple approach to identifying semantically similar questions by combining the strengths of word embeddings and Convolutional Neural Networks (CNNs). In addition, we demonstrate how the cosine similarity metric can be used to effectively compare feature vectors. Our network is trained on the Quora dataset, which contains over 400k question pairs. We experiment with different embedding approaches such as Word2Vec, Fasttext, and Doc2Vec and investigate the effects these approaches have on model performance. Our model achieves competitive results on the Quora dataset and complements the well-established evidence that CNNs can be utilized for paraphrase recognition tasks.
Simple MOSFET models intended for hand analysis are inaccurate in deep sub-micrometer process technologies and in the moderate inversion region of device operation. Accurate models, such as the Berkeley BSIM6 model, are too complex for use in hand analysis and are intended for circuit simulators. Artificial neural networks (ANNs) are efficient at capturing both linear and non-linear multivariate relationships. In this work, a straightforward modeling technique is presented using ANNs to replace the BSIM model equations. Existing open-source libraries are used to quickly build models with error rates generally below 3%. When combined with a novel approach, such as the gm/Id systematic design method, the presented models are sufficiently accurate for use in the initial sizing of analog circuit components without simulation.
Comparison of sleep characteristics measurements: a case study with a population aged 65 and above
(2020)
Good sleep is crucial for a healthy life of every person. Unfortunately, its quality often decreases with aging. A common approach to measuring the sleep characteristics is based on interviews with the subjects or letting them fill in a daily questionnaire and afterward evaluating the obtained data. However, this method has time and personal costs for the interviewer and evaluator of responses. Therefore, it would be important to execute the collection and evaluation of sleep characteristics automatically. To do that, it is necessary to investigate the level of agreement between measurements performed in a traditional way using questionnaires and measurements obtained using electronic monitoring devices. The study presented in this manuscript performs this investigation, comparing such sleep characteristics as "time going to bed", "total time in bed", "total sleep time" and "sleep efficiency". A total number of 106 night records of elderly persons (aged 65+) were analyzed. The results achieved so far reveal the fact that the degree of agreement between the two measurement methods varies substantially for different characteristics, from 31 minutes of mean difference for "time going to bed" to 77 minutes for "total sleep time". For this reason, a direct exchange of objective and subjective measuring methods is currently not possible.
Polyelectrolyte multilayer coatings (PEM) are prepared by alternative layer-by-layer deposition of cationic and anionic polyelectrolyte monolayers on charged surfaces. The thickness of the coatings ranges from nm to few μm. Their properties such as roughness, stiffness, surface charge and surface energy can be precisely tuned to fulfil different technical or biological requirements. The coating process is based on self-assembly of polyelectrolytes. Advantages of these coatings are their easy handling, no harsh chemistry and the possibility for coatings on complex geometries. The PEM coatings can be prepared from a variety of suitable polyelectrolytes. Their stability varies from very durable PEM coatings that are only soluble in strong solvents to quickly degradable, which may be applied as drug release system. One example of such a degradable PEM system is the one based on the polyelectrolyte pair Hyaluronan (HA) and Chitosan (CHI). These biopolymers originate from natural sources and show low toxicity towards human cells. However, HA/CHI multilayers show only weak adhesiveness for human umbilical vein endothelial cells (HUVEC). In this article, we summarize our approaches to enhance the HA/CHI multilayer by incorporation of a non-polymer substance –graphene oxide– to improve the cell adhesion and keep such properties as low cytotoxicity and biodegradability. Different approaches for incorporation of graphene oxide were performed and the cellular adhesion was tested by metabolic assay.
By 2019, German-based Kärcher, "the world's leading provider of cleaning technology", hat turned its professional cleaning devices into digital offerings. The data generated by these connected cleaning devices formed a key ingredient in the company's ongoing strategic shift in its B2B business: Kärcher was transforming from a seller of cleaning devices to a provider of consulting services in order to help professional cleaning companies improve their cleaning processes.
The case illustrates how the company learned to generate value from digital offerings. And it demonstrates how a family-owned company transformed its organization in order to be able to more effectively develop and provide digital offerings, while adding roles and developing technology platforms, as well as changing structures and ways of working.
In networked operating room environments, there is an emerging trend towards standardized non-proprietary communication protocols which allow to build new integration solutions and flexible human-machine interaction concepts. The most prominent endeavor is the IEEE 11073 SDC protocol. For some uses cases, it would be helpful if not just medical devices could be controlled based on SDC, but also building automation systems like light, shutters, air condition, etc. For those systems, the KNX protocol is widely used. We build an SDC-to-KNX gateway which allows to use the SDC protocol for sending commands to connected KNX devices. The first prototype system was successfully implemented at the demonstration operating room at Reutlingen University. This is a first step toward the integration of a broader variety of KNX devices.
Background
The actual task of electrocardiographic examinations is to increase the reliability of diagnosing the condition of the heart. Within the framework of this task, an important direction is the solution of the inverse problem of electrocardiography, based on the processing of electrocardiographic signals of multichannel cardio leads at known electrode coordinates in these leads (Titomir et al. Noninvasiv electrocardiotopography, 2003), (Macfarlane et al. Comprehensive Electrocardiology, 2nd ed. (Chapter 9), 2011).
Results
In order to obtain more detailed information about the electrical activity of the heart, we carry out a reconstruction of the distribution of equivalent electrical sources on the heart surface. In this area, we hold reconstruction of the equivalent sources during the cardiac cycle at relatively low hardware cost. ECG maps of electrical potentials on the surface of the torso (TSPM) and electrical sources on the surface of the heart (HSSM) were studied for different times of the cardiac cycle. We carried out a visual and quantitative comparison of these maps in the presence of pathological regions of different localization. For this purpose we used the model of the heart electrical activity, based on cellular automata.
Conclusions
The model of cellular automata allows us to consider the processes of heart excitation in the presence of pathological regions of various sizes and localization. It is shown, that changes in the distribution of electrical sources on the surface of the epicardium in the presence of pathological areas with disturbances in the conduction of heart excitation are much more noticeable than changes in ECG maps on the torso surface.
Learning factories can complement each other by training different competencies in the field of digitalisation and Industry 4.0. They depict diverse sections of the product development process and focus on various technologies. Within the framework of the International Association of Learning Factories (IALF), the operating organisations of learning factories exchange information on research, training and education. One of the aims is to develop joint projects. The article presents different concepts of cooperation between learning factories while focusing on the improvement of the development of learners competencies e.g. with a broader range of topics. A concept of a joint course between the learning factories in Bochum, Reutlingen and Darmstadt is explained in detail. The three learning factories will be examined with regard to their similarities and differences. The joint course focuses on the target group of students and the topic of digitalisation in the development and production of products. The course and its contents are explained in detail. The new learning approach is evaluated on the basis of feedback from the participants. Finally, challenges resulting from the cooperation between learning factories at different locations and with different operating models will be discussed.
The dynamic capabilities perspective is aimed at explaining how firms achieve and sustain competitive advantages, especially in environments that become volatile, uncertain, complex, and ambiguous (VUCA). In this paper, we combine factors that explain dynamic capabilities on the firm level with factors of dynamic managerial capabilities on the individual level. In addition to the dynamic capabilities theory, we draw on corporate foresight (CF) literature to test the impact of CF training. We find that both the organizational-level practices and the individual-level training of leaders are positively associated with firm-level outcomes. We further observe that this relationship is mediated by dynamic managerial capabilities (i.e., the ability of leaders to challenge current business models, make decisions under uncertainty, and reconfigure organizational resources). Our findings emphasize the importance of training leaders and building organizational CF practices to build the dynamic capabilities needed in VUCA environments.
The purpose of this paper is to investigate how motion pictures are currently used for the product presentation of fashion articles in online shops in the German, American and British markets. This study shows that the use of moving images for the presentation of fashion articles in online shops is underutilized. With the amount of data that was manageable within the scope of this chapter, no valid generalizations can be made. All described results must be understood as an indication. In order to be able to use product presentation videos meaningfully, one should consider before exactly what is the purpose of these videos. Different goals require different means. However, retailer should obtain enough information in advance to assess whether they can afford the production and post processing of these videos.
The generous feed-in tariffs (FiTs) introduced in Germany—which resulted in major growth in decentralized solar photovoltaic (PV) systems—will phase out in the coming years, making many of the existing distributed generation assets stranded. This challenge creates an opportunity for community-focused energy utilities, such as Elektrizitätswerke Schönau eG (EWS) based in Schönau, Germany, to try a new approach to assist its customers, makes the transition to a more sustainable future. This chapter describes how EWS is developing products and offering community-based solutions including peer-to-peer trading using automated platforms. Such innovative offering may lead to successful differentiation in a competitive and highly decentralized future.
The Twelfth International Conference on Advances in Databases, Knowledge, and Data Applications (DBKDA 2020) continued a series of events covering a large spectrum of topics related to advances in fundamentals on databases, evolution of relation between databases and other domains, data base technologies and content processing, as well as specifics in applications domains databases. Advances in different technologies and domains related to databases triggered substantial improvements for content processing, information indexing, and data, process and knowledge mining. The push came from Web services, artificial intelligence, and agent technologies, as well as from the generalization of the XML adoption. High-speed communications and computations, large storage capacities, and load-balancing for distributed databases access allow new approaches for content processing with incomplete patterns, advanced ranking algorithms and advanced indexing methods. Evolution on e-business, ehealth and telemedicine, bioinformatics, finance and marketing, geographical positioning systems put pressure on database communities to push the ‘de facto’ methods to support new requirements in terms of scalability, privacy, performance, indexing, and heterogeneity of both content and technology.
Purpose: Gliomas are the most common and aggressive type of brain tumors due to their infiltrative nature and rapid progression. The process of distinguishing tumor boundaries from healthy cells is still a challenging task in the clinical routine. Fluid attenuated inversion recovery (FLAIR) MRI modality can provide the physician with information about tumor infiltration. Therefore, this paper proposes a new generic deep learning architecture, namely DeepSeg, for fully automated detection and segmentation of the brain lesion using FLAIR MRI data.
Methods: The developed DeepSeg is a modular decoupling framework. It consists of two connected core parts based on an encoding and decoding relationship. The encoder part is a convolutional neural network (CNN) responsible for spatial information extraction. The resulting semantic map is inserted into the decoder part to get the full-resolution probability map. Based on modified U-Net architecture, different CNN models such as residual neural network (ResNet), dense convolutional network (DenseNet), and NASNet have been utilized in this study.
Results: The proposed deep learning architectures have been successfully tested and evaluated on-line based on MRI datasets of brain tumor segmentation (BraTS 2019) challenge, including s336 cases as training data and 125 cases for validation data. The dice and Hausdorff distance scores of obtained segmentation results are about 0.81 to 0.84 and 9.8 to 19.7 correspondingly.
Conclusion: This study showed successful feasibility and comparative performance of applying different deep learning models in a new DeepSeg framework for automated brain tumor segmentation in FLAIR MR images. The proposed DeepSeg is open source and freely available at https://github.com/razeineldin/DeepSeg/.
Introduction: Bioresorbable collagenous barrier membranes are used to prevent premature soft tissue ingrowth and to allow bone regeneration. For volume stable indications, only non-absorbable synthetic materials are available. This study investigates a new bioresorbable hydrofluoric acid (HF)-treated magnesium (Mg) mesh in a native collagen membrane for volume stable situations. Materials and Methods: HF-treated and untreated Mg were compared in direct and indirect cytocompatibility assays. In vivo, 18 New Zealand White Rabbits received each four 8 mm calvarial defects and were divided into four groups: (a) HF-treated Mg mesh/collagen membrane, (b) untreated Mg mesh/collagen membrane (c) collagen membrane and (d) sham operation. After 6, 12 and 18 weeks, Mg degradation and bone regeneration was measured using radiological and histological methods. Results: In vitro, HF-treated Mg showed higher cytocompatibility. Histopathologically, HF-Mg prevented gas cavities and was degraded by mononuclear cells via phagocytosis up to 12 weeks. Untreated Mg showed partially significant more gas cavities and a fibrous tissue reaction. Bone regeneration was not significantly different between all groups. Discussion and Conclusions: HF-Mg meshes embedded in native collagen membranes represent a volume stable and biocompatible alternative to the non-absorbable synthetic materials. HF-Mg shows less corrosion and is degraded by phagocytosis. However, the application of membranes did not result in higher bone regeneration.
Driven by digital transformation, manufacturing systems are heading towards autonomy. The implementation of autonomous elements in manufacturing systems is still a big challenge. Especially small and medium sized enterprises (SME) often lack experience to assess the degree of Autonomous Production. Therefore, a description model for the assessment of stages for Autonomous Production has been identified as a core element to support such a transformation process. In contrast to existing models, the developed SME-tailored model comprises different levels within a manufacturing system, from single manufacturing cells to the factory level. Furthermore, the model has been validated in several case studies.
The design process for a single phase, smart, universal charger for light electric vehicles, is presented. With a step up, power factor correction circuit, followed by a phase shifted, full bridge converter, with synchronous rectification on the secondary side. Due to the resistor-capacitor-diode snubber on the secondary side, the current peak at the start of power transfer, leads to false triggering during light load control with peak current mode control. The solution developed for light loads, is to change from peak current control to voltage control. This is achieved by limiting the maximum phase shift, instead of changing the reference value. For the power factor correction stage, measured and calculated efficiencies are compared as a function of the output power. The voltage and current waveforms are shown for the power factor correction circuit, and for the phase shifted bridge, the measured current waveform is compared with simulation.
Additive Manufacturing is increasingly used in the industrial sector as a result of continuous development. In the Production Planning and Control (PPC) system, AM enables an agile response in the area of detailed and process planning, especially for a large number of plants. For this purpose, a concept for a PPC system for AM is presented, which takes into account the requirements for integration into the operational enterprise software system. The technical applicability will be demonstrated by individual implemented sections. The presented solution approach promises a more efficient utilization of the plants and a more elastic use.