Open Access

After more than three decades of electronic design automation, most layouts for analog integrated circuits are still handcrafted in a laborious manual fashion today. Obverse to the highly automated synthesis tools in the digital domain (coping with the quantitative difficulty of packing more and more components onto a single chip – a desire well known as More Moore), analog layout automation struggles with the many diverse and heavily correlated functional requirements that turn the analog design problem into a More than Moore challenge. Facing this qualitative complexity, seasoned layout engineers rely on their comprehensive expert knowledge to consider all design constraints that uncompromisingly need to be satisfied. This usually involves both formally specified and nonformally communicated pieces of expert knowledge, which entails an explicit and implicit consideration of design constraints, respectively. Existing automation approaches can be basically divided into optimization algorithms (where constraint consideration occurs explicitly) and procedural generators (where constraints can only be taken into account implicitly). As investigated in this thesis, these two automation strategies follow two fundamentally different paradigms denoted as top-down automation and bottom-up automation. The major trait of top-down automation is that it requires a thorough formalization of the problem to enable a self-intelligent solution finding, whereas a bottom-up automatism –controlled by parameters– merely reproduces solutions that have been preconceived by a layout expert in advance. Since the strengths of one paradigm may compensate the weaknesses of the other, it is assumed that a combination of both paradigms –called bottom-up meets top-down– has much more potential to tackle the analog design problem in its entirety than either optimization-based or generator-based approaches alone. Against this background, the thesis at hand presents Self-organized Wiring and Arrangement of Responsive Modules (SWARM), an interdisciplinary methodology addressing the design problem with a decentralized multi-agent system. Its basic principle, similar to the roundup of a sheep herd, is to let responsive mobile layout modules (implemented as context-aware procedural generators) interact with each other inside a user-defined layout zone. Each module is allowed to autonomously move, rotate and deform itself, while a supervising control organ successively tightens the layout zone to steer the interaction towards increasingly compact (and constraint compliant) layout arrangements. Considering various principles of self-organization and incorporating ideas from existing decentralized systems, SWARM is able to evoke the phenomenon of emergence: although each module only has a limited viewpoint and selfishly pursues its personal objectives, remarkable overall solutions can emerge on the global scale. Several examples exhibit this emergent behavior in SWARM, and it is particularly interesting that even optimal solutions can arise from the module interaction. Further examples demonstrate SWARM’s suitability for floorplanning purposes and its application to practical place-and-route problems. The latter illustrates how the interacting modules take care of their respective design requirements implicitly (i.e., bottom-up) while simultaneously paying respect to high level constraints (such as the layout outline imposed top-down by the supervising control organ). Experimental results show that SWARM can outperform optimization algorithms and procedural generators both in terms of layout quality and design productivity. From an academic point of view, SWARM’s grand achievement is to tap fertile virgin soil for future works on novel bottom-up meets top-down automatisms. These may one day be the key to close the automation gap in analog layout design.

Due to the rising need for palliative care in Russia, it is crucial to provide timely and high-quality solutions for patients, relatives, and caregivers. A methodology for remote monitoring of patients in need of palliative care and the requirements will be developed for a hardware-software complex for remote monitoring of patients' health at home.

This paper investigates the possibility to effectively monitor and control the respiratory action using a very simple and non invasive technique based on a single lightweight reduced-size wireless surface electromyography (sEMG) sensor placed below the sternum. The captured sEMG signal, due to the critical sensor position, is characterized by a low energy level and it is affected by motion artifacts and cardiac noise. In this work we present a preliminary study performed on adults for assessing the correlation of the spirometry signal and the sEMG signal after the removal of the superimposed heart signal. This study and the related findings could be useful in respiratory monitoring of preterm infants.

In summary, we believe that current “sleep monitoring” consumer devices on the market must undergo a more robust validation process before being made available and distributed in the general public. This is especially noteworthy as there have been first reports in the literature that inaccurate feedback of such consumer devices can worry subjects and may even lead to compromised well-being of the user.

Parallel applications are the computational backbone of major industry trends and grand challenges in science. Whereas these applications are typically constructed for dedicated High Performance Computing clusters and supercomputers, the cloud emerges as attractive execution environment, which provides on-demand resource provisioning and a pay-per-use model. However, cloud environments require specific application properties that may restrict parallel application design. As a result, design trade-offs are required to simultaneously maximize parallel performance and benefit from cloud-specific characteristics. In this paper, we present a novel approach to assess the cloud readiness of parallel applications based on the design decisions made. By discovering and understanding the implications of these parallel design decisions on an application’s cloud readiness, our approach supports the migration of parallel applications to the cloud.We introduce an assessment procedure, its underlying meta model, and a corresponding instantiation to structure this multi-dimensional design space. For evaluation purposes, we present an extensive case study comprising three parallel applications and discuss their cloud readiness based on our approach.