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Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to the variety of scanners and imaging protocols. Over the last years, the BraTS Challenge has provided a large number of multi-institutional MRI scans as a benchmark for glioma segmentation algorithms. This paper describes our contribution to the BraTS 2022 Continuous Evaluation challenge. We propose a new ensemble of multiple deep learning frameworks namely, DeepSeg, nnU-Net, and DeepSCAN for automatic glioma boundaries detection in pre-operative MRI. It is worth noting that our ensemble models took first place in the final evaluation on the BraTS testing dataset with Dice scores of 0.9294, 0.8788, and 0.8803, and Hausdorf distance of 5.23, 13.54, and 12.05, for the whole tumor, tumor core, and enhancing tumor, respectively. Furthermore, the proposed ensemble method ranked first in the final ranking on another unseen test dataset, namely Sub-Saharan Africa dataset, achieving mean Dice scores of 0.9737, 0.9593, and 0.9022, and HD95 of 2.66, 1.72, 3.32 for the whole tumor, tumor core, and enhancing tumor, respectively.
Diese Studie untersucht den kurzfristigen Einfluss der Tagespflege auf die kindliche Entwicklung im Vergleich zur Betreuung in der Kita. Internationale Studien deuten darauf hin, dass der Besuch einer Tagespflege im Vergleich zur Kita eher negative Auswirkungen auf Kinder hat. Mithilfe der Neugeborenen-Kohorte des NEPS können wir evaluieren, ob dies auch im deutschen Kontext gilt. Wir nutzen zwei verschiedene methodische Ansätze, um den Effekt der Tagespflege zu schätzen. Unsere Ergebnisse zeigen, dass die Tagespflege für die Mehrzahl der untersuchten Entwicklungsindikatoren keinen statistisch signifikant schlechteren Einfluss auf die kindliche Entwicklung hat, außer im Bereich der Habituation.
Flame-retardant finishing of cotton fabrics using DOPO functionalized alkoxy- and amido alkoxysilane
(2023)
In the present study, DOPO-based alkoxysilane (DOPO-ETES) and amido alkoxysilane (DOPO-AmdPTES) were synthesized by one-step and without by-products as halogen-free flame retardants. The flame retardants were applied on cotton fabric utilizing sol–gel method and pad-dry-cure finishing process. The flame retardancy, the thermal stability and the combustion ehaviour of treated cotton were evaluated by surface and bottom edge ignition flame test (according to EN ISO 15025), thermogravimetric analysis (TGA) and micro-scale combustion calorimeter (MCC). Unlike CO/DOPO-ETES sample, cotton treated with DOPO-AmdPTES nanosols exhibits self-extinguishing ehaviour with high char residue, an improvement of the LOI value and a significant reduction of the PHRR, HRC and THR compared to pristine cotton. Cotton finished with DOPO-AmdPTES reveals a semi-durability after ten laundering cycles keeping the flame-retardant properties unchanged. According to the results obtained from TGA-FTIR, Py-GC/MS and XPS, the major activity of flame retardant occurs in the condensed phase via catalytic induced char formation as physical barrier along with the activity in the gas phase derived mainly from the dilution effect. The early degradation of CO/DOPO-AmdPTES compared to CO/DOPO-ETES, triggered by the cleavage of the weak bond between P and C=O, as the DFT study indicated, provides the beneficial effect of this flame retardant on the fire resistance of cellulose.
Dieser Beitrag untersucht, wer in Deutschland Bildungsminister:in wird. Zur Klärung dieser Frage entwickelten wir einen Datensatz, der die biografischen Merkmale aller Bildungsminister:innen der deutschen Bundesländer zwischen 1950 und 2020 enthält. Als Beispiel für die Nutzung des Datensatzes untersuchen wir die beiden Merkmale Geschlecht und frühere Berufserfahrung und verknüpfen diese Merkmale mit Indikatoren für die Größe und Entwicklung des Bildungsbudgets und die Dauer der Amtszeit. Wir zeigen, dass zwischen 1950 und 2020 deutlich mehr Männer als Frauen zum/zur Bildungsminister:in ernannt wurden, unabhängig davon, welche Parteien die Bildungsminister:innen stellten. Außerdem verfügt die Mehrheit der Bildungsminister:innen bei Amtsantritt nicht über vorherige Berufserfahrung als Lehrer:in. Die meisten Bildungsminister:innen haben jedoch bereits politische Erfahrung, wenn sie ihr Amt antreten. Unsere Datenbank, die die erste umfassende Erhebung biografischer Merkmale von Bildungsminister:innen in den deutschen Bundesländern enthält, steht allen interessierten Forscher:innen zur Verfügung.
The blockchain technology represents a decentralised database that stores information securely in immutable data blocks. Regarding supply chain management, these characteristics offer potentials in increasing supply chain transparency, visibility, automation, and efficiency. In this context, first token-based mapping approaches exist to transfer certain manufacturing processes to the blockchain, such as the creation or assembly of parts as well as their transfer of ownership. This paper proposes a prototypical blockchain application that adopts an authority concept and a concept of smart non-fungible tokens. The application enables the mapping of complex products in dynamic supply chains that require the auditability of changeable assembling processes on the blockchain. Finally, the paper demonstrates the practical feasibility of the proposed application based on a prototypical implementation created on the Ethereum blockchain.
In diesem Kapitel wird eine Einführung in die sich abzeichnenden Trends bei der Gestaltung der digitalen Transformation gegeben, wobei der Schwerpunkt auf digitalen Produkten, intelligenten Diensten und damit verbundenen Systemen sowie auf Methoden, Modellen und Architekturen liegt. Das primäre Ziel dieses Buches ist es, einige der neuesten Forschungsergebnisse auf diesem Gebiet hervorzuheben. Wir stellen eine Reihe von Kurzbeschreibungen der im Buch enthaltenen Kapitel zur Verfügung.
Die digitale Transformation ist die heute vorherrschende geschäftliche Transformation, die einen starken Einfluss darauf hat, wie digitale Dienstleistungen und Produkte dienstleistungsdominant gestaltet werden. Eine beliebte zugrundeliegende Theorie der Wertschöpfung und des wirtschaftlichen Austauschs, die als dienstleistungsdominante Logik (S-D) bekannt ist, kann mit vielen erfolgreichen digitalen Geschäftsmodellen verbunden werden. Allerdings ist die S-D-Logik an sich abstrakt. Unternehmen können sie nicht ohne Weiteres als Instrument für die Innovation und Gestaltung von Geschäftsmodellen nutzen. Um dies zu ändern, wird eine umfassende Ideenfindungsmethode auf der Grundlage der S-D-Logik vorgeschlagen, die als service-dominantes Design (SDD) bezeichnet wird. SDD zielt darauf ab, Unternehmen beim Übergang zu einer service- und wertorientierten Perspektive zu unterstützen. Die Methode bietet eine vereinfachte Möglichkeit, den Ideenfindungsprozess auf der Grundlage von vier Modellkomponenten zu strukturieren. Jede Komponente besteht aus praktischen Implikationen, Hilfsfragen und Visualisierungstechniken, die aus einer Literaturrecherche, einer Anwendungsfallbewertung der digitalen Mobilität und einer Fokusgruppendiskussion abgeleitet wurden. SDD ist ein erster Schritt zu einem Toolset, das etablierte Unternehmen bei der Service- und Werteorientierung im Rahmen ihrer digitalen Transformation unterstützen kann.
Unternehmen sind derzeit dabei, ihre Strategie, ihre Prozesse und ihre Informationssysteme zu verändern, um ihren Digitalisierungsgrad zu erhöhen. Das Potenzial des Internets und verwandter digitaler Technologien wie Internet der Dinge, Services Computing, Cloud Computing, künstliche Intelligenz, Big Data mit Analysen, mobile Systeme, Kollaborationsnetzwerke und cyber-physikalische Systeme treibt neue Geschäftsmodelle an und ermöglicht sie. Die Digitalisierung führt zu einer tiefgreifenden Umwälzung bestehender Unternehmen, Technologien und Volkswirtschaften und fördert die Architektur digitaler Umgebungen mit vielen eher kleinen und verteilten Strukturen. Dies hat starke Auswirkungen auf neue Wertschöpfungsmöglichkeiten und die Gestaltung digitaler Dienste und Produkte, die durch die Nutzung einer service-dominanten Logik gesteuert werden. Das Hauptergebnis des Buchkapitels erweitert Methoden für integrale digitale Strategien um wertorientierte Modelle für digitale Produkte und Dienstleistungen, die im Rahmen eines multiperspektivischen digitalen Unternehmensarchitektur-Referenzmodells definiert werden.
Die Digitalisierung, der ständige technologische Fortschritt und immer kürzere Produktlebenszyklen stellen Unternehmen derzeit vor große Herausforderungen. Um am Markt erfolgreich zu sein, müssen Geschäftsmodelle häufiger und schneller als früher an veränderte Marktbedingungen angepasst werden. Schnelle Anpassungsfähigkeit, auch Agilität genannt, ist in der heutigen Zeit ein entscheidender Wettbewerbsfaktor. Aufgrund des ständig wachsenden IT-Anteils von Produkten und der Tatsache, dass diese mit Hilfe von IT hergestellt werden, hat die Änderung des Geschäftsmodells große Auswirkungen auf die Unternehmensarchitektur (EA). Die Entwicklung von EAs ist jedoch eine sehr komplexe Aufgabe, da viele Beteiligte mit gegensätzlichen Interessen in den Entscheidungsprozess eingebunden sind. Daher ist ein hohes Maß an Zusammenarbeit erforderlich. Um Unternehmen bei der Entwicklung ihrer EA zu unterstützen, wird in diesem Artikel eine neuartige integrative Methode vorgestellt, die die Interessen der Stakeholder systematisch in die Entscheidungsfindung einbezieht. Durch die Anwendung der Methode wird die Zusammenarbeit zwischen den beteiligten Interessengruppen verbessert, indem Berührungspunkte zwischen ihnen identifiziert werden. Darüber hinaus machen die standardisierten Aktivitäten die Entscheidungsfindung transparenter und vergleichbarer, ohne die Kreativität einzuschränken.
The volume includes papers presented at the International KES Conference on Human Centred Intelligent Systems 2023 (KES HCIS 2023), held in Rome, Italy on June 14–16, 2023. This book highlights new trends and challenges in intelligent systems, which play an important part in the digital transformation of many areas of science and practice. It includes papers offering a deeper understanding of the human-centred perspective on artificial intelligence, of intelligent value co-creation, ethics, value-oriented digital models, transparency, and intelligent digital architectures and engineering to support digital services and intelligent systems, the transformation of structures in digital businesses and intelligent systems based on human practices, as well as the study of interaction and the co-adaptation of humans and systems.
Current advances in Artificial Intelligence (AI) combined with other digitalization efforts are changing the role of technology in service ecosystems. Human-centered intelligent systems and services are the target of many current digitalization efforts and part of a massive digital transformation based on digital technologies. Artificial intelligence, in particular, is having a powerful impact on new opportunities for shared value creation and the development of smart service ecosystems. Motivated by experiences and observations from digitalization projects, this paper presents new methodological experiences from academia and practice on a joint view of digital strategy and architecture of intelligent service ecosystems and explores the impact of digitalization based on real case study results. Digital enterprise architecture models serve as an integral representation of business, information, and technology perspectives of intelligent service-based enterprise systems to support management and development. This paper focuses on the novel aspect of closely aligned digital strategy and architecture models for intelligent service ecosystems and highlights the fundamental business mechanism of AI-based value creation, the corresponding digital architecture, and management models. We present key strategy-oriented architecture model perspectives for intelligent systems.
In today’s education, healthcare, and manufacturing sectors, organizations and information societies are discussing new enhancements to corporate structure and process efficiency using digital platforms. These enhancements can be achieved using digital tools. Industry 5.0 and Society 5.0 give several potentials for businesses to enhance the adaptability and efficacy of their industrial processes, paving the door for developing new business models facilitated by digital platforms. Society 5.0 can contribute to a super-intelligent society that includes the healthcare industry. In the past decade, the Internet of Things, Big Data Analytics, Neural Networks, Deep Learning, and Artificial Intelligence (AI) have revolutionized our approach to various job sectors, from manufacturing and finance to consumer products. AI is developing quickly and efficiently. We have heard of the latest artificial intelligence chatbot, ChatGPT. OpenAI created this, which has taken the internet by storm. We tested the effectiveness of a considerable language model referred to as ChatGPT on four critical questions concerning “Society 5.0”, “Healthcare 5.0”, “Industry,” and “Future Education” from the perspectives of Age 5.0.
Enterprises and societies currently face essential challenges, and digital transformation can contribute to their resolution. Enterprise architecture (EA) is useful for promoting digital transformation in global companies and information societies covering ecosystem partners. The advancement of new business models can be promoted with digital platforms and architectures for Industry 4.0 and Society 5.0. Therefore, products from the sector of healthcare, manufacturing and energy, etc. can increase in value. The adaptive integrated digital architecture framework (AIDAF) for Industry 4.0 and the design thinking approach is expected to promote and implement the digital platforms and digital products for healthcare, manufacturing and energy communities more efficiently. In this paper, we propose various cases of digital transformation where digital platforms and products are designed and evaluated for digital IT, digital manufacturing and digital healthcare with Industry 4.0 and Society 5.0. The vision of AIDAF applications to perform digital transformation in global companies is explained and referenced, extended toward the digitalized ecosystems such as Society 5.0 and Industry 4.0.
Context
Web APIs are one of the most used ways to expose application functionality on the Web, and their understandability is important for efficiently using the provided resources. While many API design rules exist, empirical evidence for the effectiveness of most rules is lacking.
Objective
We therefore wanted to study 1) the impact of RESTful API design rules on understandability, 2) if rule violations are also perceived as more difficult to understand, and 3) if demographic attributes like REST-related experience have an influence on this.
Method
We conducted a controlled Web-based experiment with 105 participants, from both industry and academia and with different levels of experience. Based on a hybrid between a crossover and a between-subjects design, we studied 12 design rules using API snippets in two complementary versions: one that adhered to a rule and one that was a violation of this rule. Participants answered comprehension questions and rated the perceived difficulty.
Results
For 11 of the 12 rules, we found that violation performed significantly worse than rule for the comprehension tasks. Regarding the subjective ratings, we found significant differences for 9 of the 12 rules, meaning that most violations were subjectively rated as more difficult to understand. Demographics played no role in the comprehension performance for violation.
Conclusions
Our results provide first empirical evidence for the importance of following design rules to improve the understandability of Web APIs, which is important for researchers, practitioners, and educators.
In recent years, 3D facial reconstructions from single images have garnered significant interest. Most of the approaches are based on 3D Morphable Model (3DMM) fitting to reconstruct the 3D face shape. Concurrently, the adoption of Generative Adversarial Networks (GAN) has been gaining momentum to improve the texture of reconstructed faces. In this paper, we propose a fundamentally different approach to reconstructing the 3D head shape from a single image by harnessing the power of GAN. Our method predicts three maps of normal vectors of the head’s frontal, left, and right poses. We are thus presenting a model-free method that does not require any prior knowledge of the object’s geometry to be reconstructed.
The key advantage of our proposed approach is the substantial improvement in reconstruction quality compared to existing methods, particularly in the case of facial regions that are self-occluded in the input image. Our method is not limited to 3d face reconstruction. It is generic and applicable to multiple kinds of 3D objects. To illustrate the versatility of our method, we demonstrate its efficacy in reconstructing the entire human body.
By delivering a model-free method capable of generating high-quality 3D reconstructions, this paper not only advances the field of 3D facial reconstruction but also provides a foundation for future research and applications spanning multiple object types. The implications of this work have the potential to extend far beyond facial reconstruction, paving the way for innovative solutions and discoveries in various domains.
The aim of this work is the development of artificial intelligence (AI) application to support the recruiting process that elevates the domain of human resource management by advancing its capabilities and effectiveness. This affects recruiting processes and includes solutions for active sourcing, i.e. active recruitment, pre-sorting, evaluating structured video interviews and discovering internal training potential. This work highlights four novel approaches to ethical machine learning. The first is precise machine learning for ethically relevant properties in image recognition, which focuses on accurately detecting and analysing these properties. The second is the detection of bias in training data, allowing for the identification and removal of distortions that could skew results. The third is minimising bias, which involves actively working to reduce bias in machine learning models. Finally, an unsupervised architecture is introduced that can learn fair results even without ground truth data. Together, these approaches represent important steps forward in creating ethical and unbiased machine learning systems.
Purpose
For the modeling, execution, and control of complex, non-standardized intraoperative processes, a modeling language is needed that reflects the variability of interventions. As the established Business Process Model and Notation (BPMN) reaches its limits in terms of flexibility, the Case Management Model and Notation (CMMN) was considered as it addresses weakly structured processes.
Methods
To analyze the suitability of the modeling languages, BPMN and CMMN models of a Robot-Assisted Minimally Invasive Esophagectomy and Cochlea Implantation were derived and integrated into a situation recognition workflow. Test cases were used to contrast the differences and compare the advantages and disadvantages of the models concerning modeling, execution, and control. Furthermore, the impact on transferability was investigated.
Results
Compared to BPMN, CMMN allows flexibility for modeling intraoperative processes while remaining understandable. Although more effort and process knowledge are needed for execution and control within a situation recognition system, CMMN enables better transferability of the models and therefore the system. Concluding, CMMN should be chosen as a supplement to BPMN for flexible process parts that can only be covered insufficiently by BPMN, or otherwise as a replacement for the entire process.
Conclusion
CMMN offers the flexibility for variable, weakly structured process parts, and is thus suitable for surgical interventions. A combination of both notations could allow optimal use of their advantages and support the transferability of the situation recognition system.
The relevance of Robotic Process Automation (RPA) has increased over the last few years. Combining RPA with Artificial Intelligence (AI) can further enhance the business value of the technology. The aim of this research was to analyze applications, terminology, benefits, and challenges of combining the two technologies. A total of 60 articles were analyzed in a systematic literature review to evaluate the aforementioned areas. The results show that by adding AI, RPA applications can be used in more complex contexts, it is possible to minimize the human factor during the development process, and AI-based decision-making can be integrated into RPA routines. This paper also presents a current overview of the used terminology. Moreover, it shows that by integrating AI, some unseen challenges in RPA projects can emerge, but also a lot of new benefits will come along with it. Based on the outcome, it is concluded that the topic offers a lot of potential, but further research and development is required. The result of this study help researches to gain an overview of the state-of-the-art in combining RPA and AI.
In den letzten Jahren hat der Trend zur Digitalisierung und Konnektivität die Kundenerwartungen an den B2B-Kundenservice verändert. Vorliegender Artikel arbeitet mit zwei klaren Studienzielen und untersucht zum einen die Rolle von IoT (Internet of Things) und Cybersicherheit als Erfolgsfaktoren für den Business-to-Business (B2B) Kundenservice und zum anderen wie eine sichere Integration zu einem Wettbewerbsvorteil auf dem deutschen Markt beitragen kann. Durch einen qualitativen Ansatz mithilfe von 20 Befragungen wurde untersucht, dass IoT und Cybersicherheit als Erfolgsfaktoren für den deutschen B2B-Kundenservice angesehen werden können. Als Ergebnis liefert diese Studie fünf Kernaussagen (Hypothesen) aus qualitativen Interviews. Neben der Diskussion allgemeiner Erfolgsfaktoren und deren Einfluss, wurde die Rolle von IoT bei der Optimierung des B2B Kundendienstes diskutiert. Zudem werden potenzielle Sicherheitsrisken in Zusammenhang mit den Dienstleistungsmodellen, notwendige Anforderungen an Cybersicherheit sowie Datenerfassung erörtert. Abschließend wurde ein Modell entwickelt, das interne und externe Aspekte aufzeigt, die dazu beitragen, dass IoT und Cybersicherheit als Erfolgsfaktoren in der Aktivitätskette des Kunden in der Pre-Sales‑, Sales- und After-Sales-Phase erlebt werden.
Dieser praxis-nahe und industrie-übergreifende Artikel liefert somit Einblicke basierend auf qualitativen Erkenntnissen für weitere Forschung in der Theorie und befähigt Organisationen das Thema ganzeinheitlich zu betrachten.
Silicon neurons represent different levels of biological details and accuracies as a trade-off between complexity and power consumption. With respect to this trade-off and high similarity to neuron behaviour models, relaxation-type oscillator circuits often yield a good compromise to emulate neurons. In this chapter, two exemplified relaxation-type silicon neurons are presented that emulate neural behaviour with energy consumption under the scale of nJ/spike. The first proposed fully CMOS relaxation SiN is based on mathematical Izhikevich model and can mimic a broad range of physiologically observable spike patterns. The results of kinds of biologically plausible output patterns and coupling process of two SiNs are presented in 0.35 μm CMOS technology. The second type is a novel ultra-low-frequency hybrid CMOS-memristive SiN based on relaxation oscillators and analog memristive devices. The hybrid SiN directly emulates neuron behaviour in the range of physiological spiking frequencies (less than 100 Hz). The relaxation oscillator is implemented and fabricated in 0.13 μm CMOS technology. An autonomous neuronal synchronization process is demonstrated with two relaxation oscillators coupled by an analog memristive device in the measurement to emulate the synchronous behaviour between spiking neurons.