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Type 1 diabetes is a chronic and a life threatening disease: an adjusted treatment and a proper management of the disease are crucial to prevent or delay the complications of diabetes. Although during the last decade the development of the artificial pancreas has presented great advances in diabetes care, the multiple daily injections therapy still represents the most widely used treatment option for type 1 diabetes. This work presents the proposal and first development stages of an application focused on guiding patients using the continuous glucose monitors and smart pens together with insulin and carbohydrates recommendations. Our proposal aims to develop a platform to integrate a series of innovative machine learning models and tools rigorously tested together with the use of the latest IoT devices to manage type 1 diabetes. The resulting system actually closes the loop, like the artificial pancreas, but in an intermittent way.
There are several intra-operative use cases which require the surgeon to interact with medical devices. I used the Leap Motion Controller as input device for three use-cases: 2D-interaction (e.g. advancing EPR data), selection of a value (e.g. room illumination brightness) and an application point and click scenario. I evaluated the Palm Mouse as the most suitable gesture solution to coordinate the mouse and advise to use the implementation using all fingers to perform a click. This small case study introduces the implementations and methods that result those recommendations.
Today many scientific works are using deep learning algorithms and time series, which can detect physiological events of interest. In sleep medicine, this is particularly relevant in detecting sleep apnea, specifically in detecting obstructive sleep apnea events. Deep learning algorithms with different architectures are used to achieve decent results in accuracy, sensitivity, etc. Although there are models that can reliably determine apnea and hypopnea events, another essential aspect to consider is the explainability of these models, i.e., why a model makes a particular decision. Another critical factor is how these deep learning models determine how severe obstructive sleep apnea is in patients based on the apnea-hypopnea index (AHI). Deep learning models trained by two approaches for AHI determination are exposed in this work. Approaches vary depending on the data format the models are fed: full-time series and window-based time series.
The potentials and opportunities created by digitized healthcare can be further customized through smart data processing and analysis using accurate patient information. This development and the associated new treatment concepts basing on digital smart sensors can lead to an increase in motivation by applying gamification approaches. This effect can also be used in the field of medical treatment, e.g. with the help of a digital spirometer combined with an app. In one of our exemplary applications, we show how to control an airplane within an app by breathing respectively inhaling and exhaling. Using this biofeedback within a game allows us to increase the motivation and fun for children that need to perform necessary exercises.
Detecting semantic similarities between sentences is still a challenge today due to the ambiguity of natural languages. In this work, we propose a simple approach to identifying semantically similar questions by combining the strengths of word embeddings and Convolutional Neural Networks (CNNs). In addition, we demonstrate how the cosine similarity metric can be used to effectively compare feature vectors. Our network is trained on the Quora dataset, which contains over 400k question pairs. We experiment with different embedding approaches such as Word2Vec, Fasttext, and Doc2Vec and investigate the effects these approaches have on model performance. Our model achieves competitive results on the Quora dataset and complements the well-established evidence that CNNs can be utilized for paraphrase recognition tasks.
This paper investigates the possibility to effectively monitor and control the respiratory action using a very simple and non invasive technique based on a single lightweight reduced-size wireless surface electromyography (sEMG) sensor placed below the sternum. The captured sEMG signal, due to the critical sensor position, is characterized by a low energy level and it is affected by motion artifacts and cardiac noise. In this work we present a preliminary study performed on adults for assessing the correlation of the spirometry signal and the sEMG signal after the removal of the superimposed heart signal. This study and the related findings could be useful in respiratory monitoring of preterm infants.
Sleep is essential to existence, much like air, water, and food, as we spend nearly one-third of our time sleeping. Poor sleep quality or disturbed sleep causes daytime solemnity, which worsens daytime activities' mental and physical qualities and raises the risk of accidents. With advancements in sensor and communication technology, sleep monitoring is moving out of specialized clinics and into our everyday homes. It is possible to extract data from traditional overnight polysomnographic recordings using more basic tools and straightforward techniques. Ballistocardiogram is an unobtrusive, non-invasive, simple, and low-cost technique for measuring cardiorespiratory parameters. In this work, we present a sensor board interface to facilitate the communication between force sensitive resistor sensor and an embedded system to provide a high-performing prototype with an efficient signal-to-noise ratio. We have utilized a multi-physical-layer approach to locate each layer on top of another, yet supporting a low-cost, compact design with easy deployment under the bed frame.
Determination of accelerometer sensor position for respiration rate detection: initial research
(2022)
Continuous monitoring of a patient's vital signs is essential in many chronic illnesses. The respiratory rate (RR) is one of the vital signs indicating breathing diseases. This article proposes the initial investigation for determining the accelerometric sensor position of a non-invasive and unobtrusive respiratory rate monitoring system. This research aims to determine the sensor position in relation to the patient, which can provide the most accurate values of the mentioned physiological parameter. In order to achieve the result, the particular system setup, including a mechanical sensor holder construction was used. The breathing signals from 5 participants were analyzed corresponding to the relaxed state. The main criterion for selecting a suitable sensor position was each patient's average acceleration amplitude excursion, which corresponds to the respiratory signal. As a result, we provided one more defined important parameter for the considered system, which was not determined before.
The field of breath analysis has developed to be of growing interest in medical diagnosis and patient monitoring. The main advantages are that it’s noninvasive, painless and repeatable in flexible cycles. Even though breath analysis is being researched for a couple of decades there are still many unanswered questions. Human breath contains volatile organic compounds which are emitted from inside the body. Some of these compounds can be assigned to specific sources, such as inflammation or cancer, but also to non health related origins. This paper gives an overview of breath analysis for the purpose of disease diagnosis and health monitoring. Therefore, literature regarding breath analysis in the medical field has been analyzed, from its early stages to the present. As a result, this paper gives an outline of the topic of breath analysis.
Information and communication technologies support telemedicine to lower health access barriers and to provide better health care. While the potential in Active Assisted Living (AAL) is increasing, it is difficult to evaluate its benefits for the user, and it requires coordinated actions to launch it. The European Commission’s action plan 2012–2020 provides a roadmap to patient empowerment and healthcare, to link up devices and technologies, and to invest in research towards the personalized medicine of the future. As a quickly developing area in medicine, telemonitoring is a demanding field in research and development. Telemonitoring is an essential component of personalized medicine, where health providers can obtain precise information on outcare or chronic patients to improve diagnosis and therapy and also help healthy persons with prevention support. Telemonitoring combines mobile and wearable devices with the personal AAL home environment, a private or (partly) supervised home, most often called ’smart home’. The focus of this workshop is on new hardware and software solutions specifically designed to be applicable in AAL environments to empower patients. This workshop presents system-oriented solutions covering wearable and AAL-embedded devices, computer science infrastructure both at the users’ and the medical premises, to handle the data and decision support systems to support diagnose and treatment.
The purpose of this paper is to examine the effects of perceived stress on traffic and road safety. One of the leading causes of stress among drivers is the feeling of having a lack of control during the driving process. Stress can result in more traffic accidents, an increase in driver errors, and an increase in traffic violations. To study this phenomenon, the Stress Perceived Questionnaire (PSQ) was used to evaluate the perceived stress while driving in a simulation. The study was conducted with participants from Germany, and they were grouped into different categories based on their emotional stability. Each participant was monitored using wearable devices that measured their instantaneous heart rate (HR). The preference for wearable devices was due to their non-intrusive and portable nature. The results of this study provide an overview of how stress can affect traffic and road safety, which can be used for future research or to implement strategies to reduce road accidents and promote traffic safety.
The importance of sleep for human life is enormous. It affects physical, mental, and psychological health. Therefore, it is vital to recognise sleep disorders in a timely manner in order to be able to initiate therapy. There are two methods for measuring sleep-related parameters - objective and subjective. Whether the substitution of a subjective method for an objective one is possible is investigated in this paper. Such replacement may bring several advantages, including increased comfort for the user. To answer this research question, a study was conducted in which 75 overnight recordings were evaluated. The primary purpose of this study was to compare both ways of measurement for total sleep time and sleep efficiency, which are essential parameters for, e.g., insomnia diagnosis and treatment. The evaluation results demonstrated that, on average, there are 32 minutes of difference between the two measurement methods when total sleep time is analysed. In contrast, on average, both measurement methods differ by 7.5% for sleep efficiency measurement. It should also be noted that people typically overestimate total sleep time and efficiency with the subjective method, where the perceived values are measured.
Generating synthetic data is a relevant point in the machine learning community. As accessible data is limited, the generation of synthetic data is a significant point in protecting patients' privacy and having more possibilities to train a model for classification or other machine learning tasks. In this work, some generative adversarial networks (GAN) variants are discussed, and an overview is given of how generative adversarial networks can be used for data generation in different fields. In addition, some common problems of the GANs and possibilities to avoid them are shown. Different evaluation methods of the generated data are also described.
This workshop addressed scientific research and development to acquire physiological signals, process signals, and extract relevant data for further analysis. There are very different domains of application, for example. Tiredness and drowsiness are responsible for a significant percentage of road accidents. There are different approaches to monitoring driver drowsiness, ranging from the driver’s steering behavior to in-depth analysis of the driver, e.g., eye tracking, blinking, yawning, or Electrocardiogram (ECG). One of the leading causes of road accidents in Egypt is trucks, buses, cars, motorcycles, and pedestrians, all sharing the same infrastructure. The result is that there are more than 12,000 fatalities in road accidents every year. Thousands are injured, and some suffer long-term disabilities. A similar effect can be observed in Germany for all types of vehicles. According to the Federal Statistical Office, a high percentage of accidents involving personal injury are directly or indirectly caused by drowsiness.
A different application domain is sleep monitoring: Healthy and sound sleep is a prerequisite for a rested mind and body. Both form the basis for physical and mental health. Healthy sleep is counteracted by sleep disorders, the medically diagnosed frequency of which increases sharply from the age of 40. Increasing acceptance can be promoted by monitoring vital signs during sleep over long periods through the exclusive use of noninvasive technologies. In the case of objective measurement, the vital signs are measured to calculate the sleep phases or sleep efficiency and, after applying the appropriate algorithms, to record the sleep quality. About a quarter of all Germans have the feeling of sleeping poorly. The disruptive factors include problems falling asleep or the subjective feeling that sleep is not restful. About half of those subjectively affected have consulted a doctor. Older people and people living alone are particularly affected. There is no doubt that sleep abnormalities can lead to poor performance throughout the day, physical/somatic illnesses, psychological problems, or even premature death. Prevention, early detection, and therapy support are relevant factors impacting the personal quality of life.
The presented approaches have different application domains but share standard methodologies and technologies. Cross-domain thinking and application are essential to successful data acquisition and processing, either with traditional or cutting-edge approaches.
Integrating tools and applications into a clinically useful system for individual continuous health data surveillance requires an architecture considering all relevant medical and technical conditions. Therefore, the requirements of an integrated system including a health app to collect and monitor sensor data to support personalized medicine are analyzed. The structure and behavior of the system are defined regarding the specific health use cases and scenarios. A vendor-independent architecture, which enables the collection of vital data from arbitrary wearables using a smartphone, is presented. The data is centrally managed and processed by attending physicians. The modular architecture allows the system to extend to new scenarios, data formats, etc. A prototypical implementation of the system shows the feasibility of the approach.
Sleep analysis using a Polysomnography system is difficult and expensive. That is why we suggest a non-invasive and unobtrusive measurement. Very few people want the cables or devices attached to their bodies during sleep. The proposed approach is to implement a monitoring system, so the subject is not bothered. As a result, the idea is a non-invasive monitoring system based on detecting pressure distribution. This system should be able to measure the pressure differences that occur during a single heartbeat and during breathing through the mattress. The system consists of two blocks signal acquisition and signal processing. This whole technology should be economical to be affordable enough for every user. As a result, preprocessed data is obtained for further detailed analysis using different filters for heartbeat and respiration detection. In the initial stage of filtration, Butterworth filters are used.
In summary, we believe that current “sleep monitoring” consumer devices on the market must undergo a more robust validation process before being made available and distributed in the general public. This is especially noteworthy as there have been first reports in the literature that inaccurate feedback of such consumer devices can worry subjects and may even lead to compromised well-being of the user.
A clinically useful system for individual continuous health data monitoring needs an architecture that takes into account all relevant medical and technical conditions. The requirements for a health app to support such a system are collected, and a vendor independent architecture is designed that allows the collection of vital data from arbitrary wearables using a smartphone. A prototypical implementation for the main scenario shows the feasibility of the approach.
Assistive environments are entering our homes faster than ever. However, there are still various barriers to be broken. One of the crucial points is a personalization of offered services and integration of assistive technologies in common objects and therefore in a regular daily routine. Recognition of sleep patterns for the preliminary sleep study is one of the Health services that could be performed in an undisturbing way. This article proposes the hardware system for the measurement of bio-vital signals necessary for initial sleep study in a nonobtrusive way. The first results confirm the potential of measurement of breathing and movement signals with the proposed system.