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Evaluation of a contactless accelerometer sensor system for heart rate monitoring during sleep
(2024)
The monitoring of a patient's heart rate (HR) is critical in the diagnosis of diseases. In the detection of sleep disorders, it also plays an important role. Several techniques have been proposed, including using sensors to record physiological signals that are automatically examined and analysed. This work aims to evaluate using a contactless HR monitoring system based on an accelerometer sensor during sleep. For this purpose, the oscillations caused by chest movements during heart contractions are recorded by an installation mounted under the bed mattress. The processing algorithm presented in this paper filters the signals and determines the HR. As a result, an average error of about 5 bpm has been documented, i.e., the system can be considered to be used for the forecasted domain.
Menopause is the permanent cessation of menstruation occurring naturally in women's aging. The most frequent symptoms associated with menopausal phases are mucosal dryness, increased weight and body fat, and changes in sleep patterns. Oral symptoms in menopause derived from saliva flow reduction can lead to dry mouth, ulcers, and alterations of taste and swallowing patterns. However, the oral health phenotype of postmenopausal women has not been characterized. The aim of the study was to determine postmenopausal women's oral phenotype, including medical history, lifestyle, and oral assessment through artificial intelligence algorithms. We enrolled 100 postmenopausal women attending the Dental School of the University of Seville were included in the study. We collected an extensive questionnaire, including lifestyle, medication, and medical history. We used an unsupervised k-means algorithm to cluster the data following standard features for data analysis. Our results showed the main oral symptoms in our postmenopausal cohort were reduced salivary flow and periodontal disease. Relying on the classical assessment of the collected data, we might have a biased evaluation of postmenopausal women. Then, we used artificial intelligence analysis to evaluate our data obtaining the main features and providing a reduced feature defining the oral health phenotype. We found 6 clusters with similar features, including medication affecting salivation or smoking as essential features to obtain different phenotypes. Thus, we could obtain main features considering differential oral health phenotypes of postmenopausal women with an integrative approach providing new tools to assess the women in the dental clinic.
Introduction to the special issue on self‑managing and hardware‑optimized database systems 2022
(2023)
Data management systems have evolved in terms of functionality, performance characteristics, complexity, and variety during the last 40 years. Particularly, the relational database management systems and the big data systems (e.g., Key-Value stores, Document stores, Graph stores and Graph Computation Systems, Spark, MapReduce/Hadoop, or Data Stream Processing Systems) have evolved with novel additions and extensions. However, the systems administration and tasks have become highly complex and expensive, especially given the simultaneous and rapid hardware evolution in processors, memory, storage, or networking. These developments present new open problems and challenges to data management systems as well as new opportunities.
The SMDB (International Workshop on Self-Managing Database Systems) and HardBD&Active (Joint International Workshop on Big Data Management on Emerging Hardware and Data Management on Virtualized Active Systems) workshops organized in conjunction with the IEEE ICDE (International Conference on Data Engineering) offered two distinct platforms for examining the above system-related challenges from different perspectives. The SMDB workshop looks into developing autonomic or self-* features in database and data management systems to tackle complex administrative tasks, while the HardBD&Active workshop focuses on harnessing hardware technologies to enhance efficiency and performance of data processing and management tasks. As a result of these workshops, we are delighted to present the third special issue of DAPD titled “Self-Managing and Hardware-Optimized Database Systems 2022,” which showcases the best contributions from the SMDB 2021/2022 and HardBD&Active 2021/2022 workshops.
Digitalization and enterprise architecture management: a perspective on benefits and challenges
(2023)
Many companies digitally transform their business models, processes, and services. They have also been using Enterprise Architecture Management approaches for a long time to synchronize corporate strategy and information technology. Such digitalization projects bring different challenges for Enterprise Architecture Management. Without understanding and addressing them, Enterprise Architecture Management projects will fail or not deliver the expected value. Since existing research has not yet addressed these challenges, they were investigated based on a qualitative expert study with leading industry experts from Europe. Furthermore, potential benefits of digitalization projects for Enterprise Architecture Management were researched. Our results provide a theoretical framework consisting of five identified challenges, triggers and a number of benefits. Furthermore, we discuss in what ways digitalization and EAM is a promising topic for future research.
Modern component-based architectural styles, e.g., microservices, enable developing the components independently from each other. However, this independence can result in problems when it comes to managing issues, such as bugs, as developer teams can freely choose their technology stacks, such as issue management systems (IMSs), e.g., Jira, GitHub, or Redmine. In the case of a microservice architecture, if an issue of a downstream microservice depends on an issue of an upstream microservice, this must be both identified and communicated, and the downstream service’s issues should link to its causing issue. However, agile project management today requires efficient communication, which is why more and more teams are communicating through comments in the issues themselves. Unfortunately, IMSs are not integrated with each other, thus, semantically linking these issues is not supported, and identifying such issue dependencies from different IMSs is time-consuming and requires manual searching in multiple IMS technologies. This results in many context switches and prevents developers from being focused and getting things done. Therefore, in this paper, we present a concept for seamlessly integrating different IMS technologies into each other and providing a better architectural context. The concept is based on augmenting the websites of issue management systems through a browser extension. We validate the approach with a prototypical implementation for the Chrome browser. For evaluation, we conducted expert interviews, which approved that the presented approach provides significant advantages for managing issues of agile microservice architectures.
Application systems often need to be deployed in different variants if requirements that influence their implementation, hosting, and configuration differ between customers. Therefore, deployment technologies, such as Ansible or Terraform, support a certain degree of variability modeling. Besides, modern application systems typically consist of various software components deployed using multiple deployment technologies that only support their proprietary, non-interoperable variability modeling concepts. The Variable Deployment Metamodel (VDMM) manages the deployment variability across heterogeneous deployment technologies based on a single variable deployment model. However, VDMM currently only supports modeling conditional components and their relations which is sometimes too coarse-grained since it requires modeling entire components, including their implementation and deployment configuration for each different component variant. Therefore, we extend VDMM by a more fine-grained approach for managing the variability of component implementations and their deployment configurations, e.g., if a cheap version of a SaaS deployment provides only a community edition of the software and not the enterprise edition, which has additional analytical reporting functionalities built-in. We show that our extended VDMM can be used to realize variable deployments across different individual deployment technologies using a case study and our prototype OpenTOSCA Vintner.
In the era of digital transformation, the notion of software quality transcends its traditional boundaries, necessitating an expansion to encompass the realms of value creation for customers and the business. Merely optimizing technical aspects of software quality can result in diminishing returns. Product discovery techniques can be seen as a powerful mechanism for crafting products that align with an expanded concept of quality - one that incorporates value creation. Previous research has shown that companies struggle to determine appropriate product discovery techniques for generating, validating, and prioritizing ideas for new products or features to ensure they meet the needs and desires of the customers and the business. For this reason, we conducted a grey literature review to identify various techniques for product discovery. First, the article provides an overview of different techniques and assesses how frequently they are mentioned in the literature review. Second, we mapped these techniques to an existing product discovery process from previous research to provide concrete guidelines for establishing product discovery in their organizations. The analysis shows, among other things, the increasing importance of techniques to structure the problem exploration process and the product strategy process. The results are interpreted regarding the importance of the techniques to practical applications and recognizable trends.
Fragestellung: Das klinische Standardverfahren und Referenz der Schlafmessung und der Klassifizierung der einzelnen Schlafstadien ist die Polysomnographie (PSG). Alternative Ansätze zu diesem aufwändigen Verfahren könnten einige Vorteile bieten, wenn die Messungen auf eine komfortablere Weise durchgeführt werden. Das Hauptziel dieser Forschung Studie ist es, einen Algorithmus für die automatische Klassifizierung von Schlafstadien zu entwickeln, der ausschließlich Bewegungs- und Atmungssignale verwendet [1].
Patienten und Methoden: Nach der Analyse der aktuellen Forschungsarbeiten haben wir multinomiale logistische Regression als Grundlage für den Ansatz gewählt [2]. Um die Genauigkeit der Auswertung zu erhöhen, wurden vier Features entwickelt, die aus Bewegungs- und Atemsignalen abgeleitet wurden. Für die Auswertung wurden die nächtlichen Aufzeichnungen von 35 Personen verwendet, die von der Charité-Universitätsmedizin Berlin zur Verfügung gestellt wurden. Das Durchschnittsalter der Teilnehmer betrug 38,6 +/– 14,5 Jahre und der BMI lag bei durchschnittlich 24,4 +/– 4,9 kg/m2. Da der Algorithmus mit drei Stadien arbeitet, wurden die Stadien N1, N2 und N3 zum NREM-Stadium zusammengeführt. Der verfügbare Datensatz wurde strikt aufgeteilt: in einen Trainingsdatensatz von etwa 100 h und in einen Testdatensatz mit etwa 160 h nächtlicher Aufzeichnungen. Beide Datensätze wiesen ein ähnliches Verhältnis zwischen Männern und Frauen auf, und der durchschnittliche BMI wies keine signifikante Abweichung auf.
Ergebnisse: Der Algorithmus wurde implementiert und lieferte erfolgreiche Ergebnisse: die Genauigkeit der Erkennung von Wach-/NREM-/REM-Phasen liegt bei 73 %, mit einem Cohen’s Kappa von 0,44 für die analysierten 19.324 Schlafepochen von jeweils 30 s. Die beobachtete gewisse Überschätzung der NREM-Phase lässt sich teilweise durch ihre Prävalenz in einem typischen Schlafmuster erklären. Selbst die Verwendung eines ausbalancierten Trainingsdatensatzes konnte dieses Problem nicht vollständig lösen.
Schlussfolgerungen: Die erreichten Ergebnisse haben die Tauglichkeit des Ansatzes prinzipiell bestätigt. Dieser hat den Vorteil, dass nur Bewegungs- und Atemsignale verwendet werden, die mit weniger Aufwand und komfortabler für Benutzer aufgezeichnet werden können als z. B. Herz- oder EEG-Signale. Daher stellt das neue System eine deutliche Verbesserung im Vergleich zu bestehenden Ansätzen dar. Die Zusammenführung der beschriebenen algorithmischen Software mit dem in [1] beschriebenen Hardwaresystem zur Messung von Atem- und Körperbewegungssignalen zu einem autonomen, berührungslosen System zur kontinuierlichen Schlafüberwachung ist eine mögliche Richtung zukünftiger Arbeiten.
Assistant platforms
(2023)
Many assistant systems have evolved toward assistant platforms. These platforms combine a range of resources from various actors via a declarative and generative interface. Among the examples are voice-oriented assistant platforms like Alexa and Siri, as well as text-oriented assistant platforms like ChatGPT and Bard. They have emerged as valuable tools for handling tasks without requiring deeper domain expertise and have received large attention with the present advances in generative artificial intelligence. In view of their growing popularity, this Fundamental outlines the key characteristics and capabilities that define assistant platforms. The former comprise a multi-platform architecture, a declarative interface, and a multi-platform ecosystem, while the latter include capabilities for composition, integration, prediction, and generativity. Based on this framework, a research agenda is proposed along the capabilities and affordances for assistant platforms.
Near-Data Processing (NDP) is a key computing paradigm for reducing the ever growing time and energy costs of data transport versus computations. With their flexibility, FPGAs are an especially suitable compute element for NDP scenarios. Even more promising is the exploitation of novel and future non-volatile memory (NVM) technologies for NDP, which aim to achieve DRAM-like latencies and throughputs, while providing large capacity non-volatile storage.
Experimentation in using FPGAs in such NVM-NDP scenarios has been hindered, though, by the fact that the NVM devices/FPGA boards are still very rare and/or expensive. It thus becomes useful to emulate the access characteristics of current and future NVMs using off-the-shelf DRAMs. If such emulation is sufficiently accurate, the resulting FPGA-based NDP computing elements can be used for actual full-stack hardware/software benchmarking, e.g., when employed to accelerate a database.
For this use, we present NVMulator, an open-source easy-to-use hardware emulation module that can be seamlessly inserted between the NDP processing elements on the FPGA and a conventional DRAM-based memory system. We demonstrate that, with suitable parametrization, the emulated NVM can come very close to the performance characteristics of actual NVM technologies, specifically Intel Optane. We achieve 0.62% and 1.7% accuracy for cache line sized accesses for read and write operations, while utilizing only 0.54% of LUT logic resources on a Xilinx/AMD AU280 UltraScale+ FPGA board. We consider both file-system as well as database access patterns, examining the operation of the RocksDB database when running on real or emulated Optane-technology memories.
Context
Web APIs are one of the most used ways to expose application functionality on the Web, and their understandability is important for efficiently using the provided resources. While many API design rules exist, empirical evidence for the effectiveness of most rules is lacking.
Objective
We therefore wanted to study 1) the impact of RESTful API design rules on understandability, 2) if rule violations are also perceived as more difficult to understand, and 3) if demographic attributes like REST-related experience have an influence on this.
Method
We conducted a controlled Web-based experiment with 105 participants, from both industry and academia and with different levels of experience. Based on a hybrid between a crossover and a between-subjects design, we studied 12 design rules using API snippets in two complementary versions: one that adhered to a rule and one that was a violation of this rule. Participants answered comprehension questions and rated the perceived difficulty.
Results
For 11 of the 12 rules, we found that violation performed significantly worse than rule for the comprehension tasks. Regarding the subjective ratings, we found significant differences for 9 of the 12 rules, meaning that most violations were subjectively rated as more difficult to understand. Demographics played no role in the comprehension performance for violation.
Conclusions
Our results provide first empirical evidence for the importance of following design rules to improve the understandability of Web APIs, which is important for researchers, practitioners, and educators.
The relevance of Robotic Process Automation (RPA) has increased over the last few years. Combining RPA with Artificial Intelligence (AI) can further enhance the business value of the technology. The aim of this research was to analyze applications, terminology, benefits, and challenges of combining the two technologies. A total of 60 articles were analyzed in a systematic literature review to evaluate the aforementioned areas. The results show that by adding AI, RPA applications can be used in more complex contexts, it is possible to minimize the human factor during the development process, and AI-based decision-making can be integrated into RPA routines. This paper also presents a current overview of the used terminology. Moreover, it shows that by integrating AI, some unseen challenges in RPA projects can emerge, but also a lot of new benefits will come along with it. Based on the outcome, it is concluded that the topic offers a lot of potential, but further research and development is required. The result of this study help researches to gain an overview of the state-of-the-art in combining RPA and AI.
Purpose
For the modeling, execution, and control of complex, non-standardized intraoperative processes, a modeling language is needed that reflects the variability of interventions. As the established Business Process Model and Notation (BPMN) reaches its limits in terms of flexibility, the Case Management Model and Notation (CMMN) was considered as it addresses weakly structured processes.
Methods
To analyze the suitability of the modeling languages, BPMN and CMMN models of a Robot-Assisted Minimally Invasive Esophagectomy and Cochlea Implantation were derived and integrated into a situation recognition workflow. Test cases were used to contrast the differences and compare the advantages and disadvantages of the models concerning modeling, execution, and control. Furthermore, the impact on transferability was investigated.
Results
Compared to BPMN, CMMN allows flexibility for modeling intraoperative processes while remaining understandable. Although more effort and process knowledge are needed for execution and control within a situation recognition system, CMMN enables better transferability of the models and therefore the system. Concluding, CMMN should be chosen as a supplement to BPMN for flexible process parts that can only be covered insufficiently by BPMN, or otherwise as a replacement for the entire process.
Conclusion
CMMN offers the flexibility for variable, weakly structured process parts, and is thus suitable for surgical interventions. A combination of both notations could allow optimal use of their advantages and support the transferability of the situation recognition system.
Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to the variety of scanners and imaging protocols. Over the last years, the BraTS Challenge has provided a large number of multi-institutional MRI scans as a benchmark for glioma segmentation algorithms. This paper describes our contribution to the BraTS 2022 Continuous Evaluation challenge. We propose a new ensemble of multiple deep learning frameworks namely, DeepSeg, nnU-Net, and DeepSCAN for automatic glioma boundaries detection in pre-operative MRI. It is worth noting that our ensemble models took first place in the final evaluation on the BraTS testing dataset with Dice scores of 0.9294, 0.8788, and 0.8803, and Hausdorf distance of 5.23, 13.54, and 12.05, for the whole tumor, tumor core, and enhancing tumor, respectively. Furthermore, the proposed ensemble method ranked first in the final ranking on another unseen test dataset, namely Sub-Saharan Africa dataset, achieving mean Dice scores of 0.9737, 0.9593, and 0.9022, and HD95 of 2.66, 1.72, 3.32 for the whole tumor, tumor core, and enhancing tumor, respectively.
The scoring of sleep stages is one of the essential tasks in sleep analysis. Since a manual procedure requires considerable human and financial resources, and incorporates some subjectivity, an automated approach could result in several advantages. There have been many developments in this area, and in order to provide a comprehensive overview, it is essential to review relevant recent works and summarise the characteristics of the approaches, which is the main aim of this article. To achieve it, we examined articles published between 2018 and 2022 that dealt with the automated scoring of sleep stages. In the final selection for in-depth analysis, 125 articles were included after reviewing a total of 515 publications. The results revealed that automatic scoring demonstrates good quality (with Cohen's kappa up to over 0.80 and accuracy up to over 90%) in analysing EEG/EEG + EOG + EMG signals. At the same time, it should be noted that there has been no breakthrough in the quality of results using these signals in recent years. Systems involving other signals that could potentially be acquired more conveniently for the user (e.g. respiratory, cardiac or movement signals) remain more challenging in the implementation with a high level of reliability but have considerable innovation capability. In general, automatic sleep stage scoring has excellent potential to assist medical professionals while providing an objective assessment.
Enterprises and societies currently face essential challenges, and digital transformation can contribute to their resolution. Enterprise architecture (EA) is useful for promoting digital transformation in global companies and information societies covering ecosystem partners. The advancement of new business models can be promoted with digital platforms and architectures for Industry 4.0 and Society 5.0. Therefore, products from the sector of healthcare, manufacturing and energy, etc. can increase in value. The adaptive integrated digital architecture framework (AIDAF) for Industry 4.0 and the design thinking approach is expected to promote and implement the digital platforms and digital products for healthcare, manufacturing and energy communities more efficiently. In this paper, we propose various cases of digital transformation where digital platforms and products are designed and evaluated for digital IT, digital manufacturing and digital healthcare with Industry 4.0 and Society 5.0. The vision of AIDAF applications to perform digital transformation in global companies is explained and referenced, extended toward the digitalized ecosystems such as Society 5.0 and Industry 4.0.
Current advances in Artificial Intelligence (AI) combined with other digitalization efforts are changing the role of technology in service ecosystems. Human-centered intelligent systems and services are the target of many current digitalization efforts and part of a massive digital transformation based on digital technologies. Artificial intelligence, in particular, is having a powerful impact on new opportunities for shared value creation and the development of smart service ecosystems. Motivated by experiences and observations from digitalization projects, this paper presents new methodological experiences from academia and practice on a joint view of digital strategy and architecture of intelligent service ecosystems and explores the impact of digitalization based on real case study results. Digital enterprise architecture models serve as an integral representation of business, information, and technology perspectives of intelligent service-based enterprise systems to support management and development. This paper focuses on the novel aspect of closely aligned digital strategy and architecture models for intelligent service ecosystems and highlights the fundamental business mechanism of AI-based value creation, the corresponding digital architecture, and management models. We present key strategy-oriented architecture model perspectives for intelligent systems.
In today’s education, healthcare, and manufacturing sectors, organizations and information societies are discussing new enhancements to corporate structure and process efficiency using digital platforms. These enhancements can be achieved using digital tools. Industry 5.0 and Society 5.0 give several potentials for businesses to enhance the adaptability and efficacy of their industrial processes, paving the door for developing new business models facilitated by digital platforms. Society 5.0 can contribute to a super-intelligent society that includes the healthcare industry. In the past decade, the Internet of Things, Big Data Analytics, Neural Networks, Deep Learning, and Artificial Intelligence (AI) have revolutionized our approach to various job sectors, from manufacturing and finance to consumer products. AI is developing quickly and efficiently. We have heard of the latest artificial intelligence chatbot, ChatGPT. OpenAI created this, which has taken the internet by storm. We tested the effectiveness of a considerable language model referred to as ChatGPT on four critical questions concerning “Society 5.0”, “Healthcare 5.0”, “Industry,” and “Future Education” from the perspectives of Age 5.0.
Unternehmen sind derzeit dabei, ihre Strategie, ihre Prozesse und ihre Informationssysteme zu verändern, um ihren Digitalisierungsgrad zu erhöhen. Das Potenzial des Internets und verwandter digitaler Technologien wie Internet der Dinge, Services Computing, Cloud Computing, künstliche Intelligenz, Big Data mit Analysen, mobile Systeme, Kollaborationsnetzwerke und cyber-physikalische Systeme treibt neue Geschäftsmodelle an und ermöglicht sie. Die Digitalisierung führt zu einer tiefgreifenden Umwälzung bestehender Unternehmen, Technologien und Volkswirtschaften und fördert die Architektur digitaler Umgebungen mit vielen eher kleinen und verteilten Strukturen. Dies hat starke Auswirkungen auf neue Wertschöpfungsmöglichkeiten und die Gestaltung digitaler Dienste und Produkte, die durch die Nutzung einer service-dominanten Logik gesteuert werden. Das Hauptergebnis des Buchkapitels erweitert Methoden für integrale digitale Strategien um wertorientierte Modelle für digitale Produkte und Dienstleistungen, die im Rahmen eines multiperspektivischen digitalen Unternehmensarchitektur-Referenzmodells definiert werden.
Die Digitalisierung, der ständige technologische Fortschritt und immer kürzere Produktlebenszyklen stellen Unternehmen derzeit vor große Herausforderungen. Um am Markt erfolgreich zu sein, müssen Geschäftsmodelle häufiger und schneller als früher an veränderte Marktbedingungen angepasst werden. Schnelle Anpassungsfähigkeit, auch Agilität genannt, ist in der heutigen Zeit ein entscheidender Wettbewerbsfaktor. Aufgrund des ständig wachsenden IT-Anteils von Produkten und der Tatsache, dass diese mit Hilfe von IT hergestellt werden, hat die Änderung des Geschäftsmodells große Auswirkungen auf die Unternehmensarchitektur (EA). Die Entwicklung von EAs ist jedoch eine sehr komplexe Aufgabe, da viele Beteiligte mit gegensätzlichen Interessen in den Entscheidungsprozess eingebunden sind. Daher ist ein hohes Maß an Zusammenarbeit erforderlich. Um Unternehmen bei der Entwicklung ihrer EA zu unterstützen, wird in diesem Artikel eine neuartige integrative Methode vorgestellt, die die Interessen der Stakeholder systematisch in die Entscheidungsfindung einbezieht. Durch die Anwendung der Methode wird die Zusammenarbeit zwischen den beteiligten Interessengruppen verbessert, indem Berührungspunkte zwischen ihnen identifiziert werden. Darüber hinaus machen die standardisierten Aktivitäten die Entscheidungsfindung transparenter und vergleichbarer, ohne die Kreativität einzuschränken.
Die digitale Transformation ist die heute vorherrschende geschäftliche Transformation, die einen starken Einfluss darauf hat, wie digitale Dienstleistungen und Produkte dienstleistungsdominant gestaltet werden. Eine beliebte zugrundeliegende Theorie der Wertschöpfung und des wirtschaftlichen Austauschs, die als dienstleistungsdominante Logik (S-D) bekannt ist, kann mit vielen erfolgreichen digitalen Geschäftsmodellen verbunden werden. Allerdings ist die S-D-Logik an sich abstrakt. Unternehmen können sie nicht ohne Weiteres als Instrument für die Innovation und Gestaltung von Geschäftsmodellen nutzen. Um dies zu ändern, wird eine umfassende Ideenfindungsmethode auf der Grundlage der S-D-Logik vorgeschlagen, die als service-dominantes Design (SDD) bezeichnet wird. SDD zielt darauf ab, Unternehmen beim Übergang zu einer service- und wertorientierten Perspektive zu unterstützen. Die Methode bietet eine vereinfachte Möglichkeit, den Ideenfindungsprozess auf der Grundlage von vier Modellkomponenten zu strukturieren. Jede Komponente besteht aus praktischen Implikationen, Hilfsfragen und Visualisierungstechniken, die aus einer Literaturrecherche, einer Anwendungsfallbewertung der digitalen Mobilität und einer Fokusgruppendiskussion abgeleitet wurden. SDD ist ein erster Schritt zu einem Toolset, das etablierte Unternehmen bei der Service- und Werteorientierung im Rahmen ihrer digitalen Transformation unterstützen kann.
The volume includes papers presented at the International KES Conference on Human Centred Intelligent Systems 2023 (KES HCIS 2023), held in Rome, Italy on June 14–16, 2023. This book highlights new trends and challenges in intelligent systems, which play an important part in the digital transformation of many areas of science and practice. It includes papers offering a deeper understanding of the human-centred perspective on artificial intelligence, of intelligent value co-creation, ethics, value-oriented digital models, transparency, and intelligent digital architectures and engineering to support digital services and intelligent systems, the transformation of structures in digital businesses and intelligent systems based on human practices, as well as the study of interaction and the co-adaptation of humans and systems.
In diesem Kapitel wird eine Einführung in die sich abzeichnenden Trends bei der Gestaltung der digitalen Transformation gegeben, wobei der Schwerpunkt auf digitalen Produkten, intelligenten Diensten und damit verbundenen Systemen sowie auf Methoden, Modellen und Architekturen liegt. Das primäre Ziel dieses Buches ist es, einige der neuesten Forschungsergebnisse auf diesem Gebiet hervorzuheben. Wir stellen eine Reihe von Kurzbeschreibungen der im Buch enthaltenen Kapitel zur Verfügung.
Dieses forschungsorientierte Buch enthält wichtige Beiträge zur Gestaltung der digitalen Transformation. Es umfasst die folgenden Hauptabschnitte in 20 Kapiteln:
- Digitale Transformation
- Digitales Geschäft
- Digitale Architektur
- Entscheidungshilfe
- Digitale Anwendungen
Es konzentriert sich auf digitale Architekturen für intelligente digitale Produkte und Dienstleistungen und ist eine wertvolle Ressource für Forscher, Doktoranden, Postgraduierte, Absolventen, Studenten, Akademiker und Praktiker, die sich für die digitale Transformation interessieren.
Identifikation von Schlaf- und Wachzuständen durch die Auswertung von Atem- und Bewegungssignalen
(2021)
Context: Companies that operate in the software-intensive business are confronted with high market dynamics, rapidly evolving technologies as well as fast-changing customer behavior. Traditional product roadmapping practices, such as fixed-time-based charts including detailed planned features, products, or services typically fail in such environments. Until now, the underlying reasons for the failure of product roadmaps in a dynamic and uncertain market environment are not widely analyzed and understood.
Objective: This paper aims to identify current challenges and pitfalls practitioners face when developing and handling product roadmaps in a dynamic and uncertain market environment.
Method: To reach our objective we conducted a grey literature review (GLR).
Results: Overall, we identified 40 relevant papers, from which we could extract 11 challenges of the application of product roadmapping in a dynamic and uncertain market environment. The analysis of the articles showed that the major challenges for practitioners originate from overcoming a feature-driven mindset, not including a lot of details in the product roadmap, and ensuring that the content of the roadmap is not driven by management or expert opinion.
Context: Nowadays the market environment is characterized by high uncertainties due to high market dynamics, confronting companies with new challenges in creating and updating product roadmaps. Most companies are still using traditional approaches which typically fail in such environments. Therefore, companies are seeking opportunities for new product roadmapping approaches.
Objective: This paper presents good practices to support companies better understand what factors are required to conduct a successful product roadmapping in a dynamic and uncertain market environment.
Method: Based on a grey literature review, essential aspects for conducting product roadmapping in a dynamic and uncertain market environment were identified. Expert workshops were then held with two researchers and three practitioners to develop best practices and the proposed approach for an outcome-driven roadmap. These results were then given to another set of practitioners and their perceptions were gathered through interviews.
Results: The study results in the development of 9 good practices that provide practitioners with insights into what aspects are crucial for product roadmapping in a dynamic and uncertain market environment. Moreover, we propose an approach to product roadmapping that includes providing a flexible structure and focusing on delivering value to the customer and the business. To ensure the latter, this approach consists of the main items outcome hypothesis, validated outcomes, and discovered outputs.
Turning students into Industry 4.0 entrepreneurs: design and evaluation of a tailored study program
(2022)
Startups in the field of Industry 4.0 could be a huge driver of innovation for many industry sectors such as manufacturing. However, there is a lack of education programs to ensure a sufficient number of well-trained founders and thus a supply of such startups. Therefore, this study presents the design, implementation, and evaluation of a university course tailored to the characteristics of Industry 4.0 entrepreneurship. Educational design-based research was applied with a focus on content and teaching concept. The study program was first implemented in 2021 at a German university of applied sciences with 25 students, of which 22 participated in the evaluation. The evaluation of the study program was conducted with a pretest–posttest-design targeting three areas: (1) knowledge about the application domain, (2) entrepreneurial intention and (3) psychological characteristics. The entrepreneurial intention was measured based on the theory of planned behavior. For measuring psychological characteristics, personality traits associated with entrepreneurship were used. Considering the study context and the limited external validity of the study, the following can be identified in particular: The results show that a university course can improve participants' knowledge of this particular area. In addition, perceived behavioral control of starting an Industry 4.0 startup was enhanced. However, the results showed no significant effects on psychological characteristics.
Enterprises and societies currently face crucial challenges, while Society 5.0 can contribute to a supersmart society, especially for manufacturing and healthcare, and Industry 4.0 becomes important in the global manufacturing industry. Smart energy digital platforms are architected to manage energy supply efficiently. Furthermore, the above digital platforms are expected to collect various kinds of data and analyze Big Data for the trends in the sharing economy in ecosystems. The adaptive integrated digital architecture framework (AIDAF) for Design Thinking Approach with Risk Management is expected to make an alignment with digital IT strategy. In this paper, we propose that various energy management systems and related digital platforms are designed and implemented in an alignment to digital IT strategy for sharing economy toward Society 5.0, with the AIDAF framework for Design Thinking Approach with Risk Management. The vision of AIDAF applications to enable sharing economy and digital platforms is explained and extended in the context of Society 5.0. In addition, challenges and future activities for this area are discussed that cover the directions of smart energy for Society 5.0.
An autonomous vehicle is a robotic vehicle with decision and action capability capable of performing assigned tasks without or with minimal human intervention. Autonomous cars have been in development for many years. The Society of Automotive Engineers (SAE International) published in 2014 a classification in five levels of driving automation, with level 0 corresponding to completely manual driving, and level 5 to an ideal dream where the vehicle would be able to navigate entirely autonomously for all missions and in all environments. This work addressed the navigation of an autonomous vehicle in general. We focus on one of the most complex scenarios of the road network and crossing of road intersections. In this paper, the critical features of autonomous intelligent vehicles are reviewed. Furthermore, the associated problems are presented, and the most advanced solutions are derived. This article aims to allow a novice in this field to understand the different facets of localization and perception problems for autonomous vehicles.
The volume includes papers presented at the International KES Conference on Human Centred Intelligent Systems 2022 (KES HCIS 2022), held in Rhodes, Greece on June 20–22, 2022. This book highlights new trends and challenges in intelligent systems, which play an important part in the digital transformation of many areas of science and practice. It includes papers offering a deeper understanding of the human-centred perspective on artificial intelligence, of intelligent value co-creation, ethics, value-oriented digital models, transparency, and intelligent digital architectures and engineering to support digital services and intelligent systems, the transformation of structures in digital businesses and intelligent systems based on human practices, as well as the study of interaction and the co-adaptation of humans and systems.
Since half a decade, there has been an increasing interest in Robotic Process Automation (RPA) by business firms. However, academic literature has been lacking attention to RPA, before adopting the topic to a larger extent. The aim of this study is to review and structure the latest state of scholarly research on RPA. This chapter is based on a systematic literature review that is used as a basis to develop a conceptual framework to structure the field. Our study shows that some areas of RPA have been extensively examined by many authors, e.g. potential benefits of RPA. Other categories, such as empirical studies on adoption of RPA or organisational readiness models, have remained research gaps.
Data analysis is becoming increasingly important to pursue organizational goals, especially in the context of Industry 4.0, where a wide variety of data is available. Here numerous challenges arise, especially when using unstructured data. However, this subject has not been focused by research so far. This research paper addresses this gap, which is interesting for science and practice as well. In a study three major challenges of using unstructured data has been identified: analytical know-how, data issues, variety. Additionally, measures how to improve the analysis of unstructured data in the industry 4.0 context are described. Therefore, the paper provides empirical insights about challenges and potential measures when analyzing unstructured data. The findings are presented in a framework, too. Hence, next steps of the research project and future research points become apparent.
Purpose
Supporting the surgeon during surgery is one of the main goals of intelligent ORs. The OR-Pad project aims to optimize the information flow within the perioperative area. A shared information space should enable appropriate preparation and provision of relevant information at any time before, during, and after surgery.
Methods
Based on previous work on an interaction concept and system architecture for the sterile OR-Pad system, we designed a user interface for mobile and intraoperative (stationary) use, focusing on the most important functionalities like clear information provision to reduce information overload. The concepts were transferred into a high-fidelity prototype for demonstration purposes. The prototype was evaluated from different perspectives, including a usability study.
Results
The prototype’s central element is a timeline displaying all available case information chronologically, like radiological images, labor findings, or notes. This information space can be adapted for individual purposes (e.g., highlighting a tumor, filtering for own material). With the mobile and intraoperative mode of the system, relevant information can be added, preselected, viewed, and extended during the perioperative process. Overall, the evaluation showed good results and confirmed the vision of the information system.
Conclusion
The high-fidelity prototype of the information system OR-Pad focuses on supporting the surgeon via a timeline making all available case information accessible before, during, and after surgery. The information space can be personalized to enable targeted support. Further development is reasonable to optimize the approach and address missing or insufficient aspects, like the holding arm and sterility concept or new desired features.
Background
Personalized medicine requires the integration and analysis of vast amounts of patient data to realize individualized care. With Surgomics, we aim to facilitate personalized therapy recommendations in surgery by integration of intraoperative surgical data and their analysis with machine learning methods to leverage the potential of this data in analogy to Radiomics and Genomics.
Methods
We defined Surgomics as the entirety of surgomic features that are process characteristics of a surgical procedure automatically derived from multimodal intraoperative data to quantify processes in the operating room. In a multidisciplinary team we discussed potential data sources like endoscopic videos, vital sign monitoring, medical devices and instruments and respective surgomic features. Subsequently, an online questionnaire was sent to experts from surgery and (computer) science at multiple centers for rating the features’ clinical relevance and technical feasibility.
Results
In total, 52 surgomic features were identified and assigned to eight feature categories. Based on the expert survey (n = 66 participants) the feature category with the highest clinical relevance as rated by surgeons was “surgical skill and quality of performance” for morbidity and mortality (9.0 ± 1.3 on a numerical rating scale from 1 to 10) as well as for long-term (oncological) outcome (8.2 ± 1.8). The feature category with the highest feasibility to be automatically extracted as rated by (computer) scientists was “Instrument” (8.5 ± 1.7). Among the surgomic features ranked as most relevant in their respective category were “intraoperative adverse events”, “action performed with instruments”, “vital sign monitoring”, and “difficulty of surgery”.
Conclusion
Surgomics is a promising concept for the analysis of intraoperative data. Surgomics may be used together with preoperative features from clinical data and Radiomics to predict postoperative morbidity, mortality and long-term outcome, as well as to provide tailored feedback for surgeons.
Personalized remote healthcare monitoring is in continuous development due to the technology improvements of sensors and wearable electronic systems. A state of the art of research works on wearable sensors for healthcare applications is presented in this work. Furthermore, a state of the art of wearable devices, chest and wrist band and smartwatches available on the market for health and sport monitoring is presented in this paper. Many activity trackers are commercially available. The prices are continuously reducing and the performances are improving, but commercial devices do not provide raw data and are therefore not useful for research purposes.
Gamification is one of the recognized methods of motivating people in various life processes, and it has spread to many spheres of life, including healthcare. This article proposes a system design for long-term care patients using the method mentioned. The proposed system aims to increase patient engagement in the treatment and rehabilitation process via gamification. Literature research on available and earlier proposed systems was conducted to develop a suited system design. The primary target group includes bedridden patients and a sedentary lifestyle (predominantly lying in bed). One of the main criteria for selecting a suitable option was its contactless realization for the mentioned target groups in long-term care cases. As a result, we developed the system design for hardware and software that could prevent bedsores and other health problems from occurring because of low activity. The proposed design can be tested in hospitals, nursing homes, and rehabilitation centers.
In recent decades, it can be observed that a steady increase in the volume of tourism is a stable trend. To offer travel opportunities to all groups, it is also necessary to prepare offers for people in need of long-term care or people with disabilities. One of the ways to improve accessibility could be digital technologies, which could help in planning as well as in carrying out trips. In the work presented, a study of barriers was first conducted, which led to selecting technologies for a test setup after analysis. The main focus was on a mobile app with travel information and 360° tours. The evaluation results showed that both technologies could increase accessibility, but some essential aspects (such as usability, completeness, relevance, etc.) need to be considered when implementing them.
The digital twin concept has been widely known for asset monitoring in the industry for a long time. A clear example is the automotive industry. Recently, there has also been significant interest in the application of digital twins in healthcare, especially in genomics in what is known as precision medicine. This work focuses on another medical speciality where digital twins can be applied, sleep medicine. However, there is still great controversy about the fundamentals that constitute digital twins, such as what this concept is based on and how it can be included in healthcare effectively and sustainably. This article reviews digital twins and their role so far in what is known as personalized medicine. In addition, a series of steps will be exposed for a possible implementation of a digital twin for a patient suffering from sleep disorders. For this, artificial intelligence techniques, clinical data management, and possible solutions for explaining the results derived from artificial intelligence models will be addressed.
In many cases continuous monitoring of vital signals is required and low intrusiveness is an important requirement. Incorporating monitoring systems in the hospital or home bed could have benefits for patients and caregivers. The objective of this work is the definition of a measurement protocol and the creation of a data set of measurements using commercial and low-cost prototypes devices to estimate heart rate and breathing rate. The experimental data will be used to compare results achieved by the devices and to develop algorithms for feature extraction of vital signals.
There have been substantial research efforts for algorithms to improve continuous and automated assessment of various health-related questions in recent years. This paper addresses the deployment gap between those improving algorithms and their usability in care and mobile health applications. In practice, most algorithms require significant and founded technical knowledge to be deployed at home or support healthcare professionals. Therefore, the digital participation of persons in need of health care professionals lacks a usable interface to use the current technological advances. In this paper, we propose applying algorithms taken from research as web-based microservices following the common approach of a RESTful service to bridge the gap and make algorithms accessible to caregivers and patients without technical knowledge and extended hardware capabilities. We address implementation details, interpretation and realization of guidelines, and privacy concerns using our self-implemented example. Also, we address further usability guidelines and our approach to those.
Glioblastomas are the most aggressive fast-growing primary brain cancer which originate in the glial cells of the brain. Accurate identification of the malignant brain tumor and its sub-regions is still one of the most challenging problems in medical image segmentation. The Brain Tumor Segmentation Challenge (BraTS) has been a popular benchmark for automatic brain glioblastomas segmentation algorithms since its initiation. In this year, BraTS 2021 challenge provides the largest multi-parametric (mpMRI) dataset of 2,000 pre-operative patients. In this paper, we propose a new aggregation of two deep learning frameworksnamely, DeepSeg and nnU-Net for automatic glioblastoma recognition in pre-operative mpMRI. Our ensemble method obtains Dice similarity scores of 92.00, 87.33, and 84.10 and Hausdorff Distances of 3.81, 8.91, and 16.02 for the enhancing tumor, tumor core, and whole tumor regions, respectively, on the BraTS 2021 validation set, ranking us among the top ten teams. These experimental findings provide evidence that it can be readily applied clinically and thereby aiding in the brain cancer prognosis, therapy planning, and therapy response monitoring. A docker image for reproducing our segmentation results is available online at (https://hub.docker.com/r/razeineldin/deepseg21).
Database management systems and K/V-Stores operate on updatable datasets – massively exceeding the size of available main memory. Tree-based K/V storage management structures became particularly popular in storage engines. B+ -Trees [1, 4] allow constant search performance, however write-heavy workloads yield in inefficient write patterns to secondary storage devices and poor performance characteristics. LSM-Trees [16, 23] overcome this issue by horizontal partitioning fractions of data – small enough to fully reside in main memory, but require frequent maintenance to sustain search performance.
Firstly, we propose Multi-Version Partitioned BTrees (MV-PBT) as sole storage and index management structure in key-sorted storage engines like K/V-Stores. Secondly, we compare MV-PBT against LSM-Trees. The logical horizontal partitioning in MV-PBT allows leveraging recent advances in modern B+ -Tree techniques in a small transparent and memory resident portion of the structure. Structural properties sustain steady read performance, yielding efficient write patterns and reducing write amplification.
We integrated MV-PBT in the WiredTiger [15] KV storage engine. MV-PBT offers an up to 2× increased steady throughput in comparison to LSM-Trees and several orders of magnitude in comparison to B+ -Trees in a YCSB [5] workload.
Purpose
Context awareness in the operating room (OR) is important to realize targeted assistance to support actors during surgery. A situation recognition system (SRS) is used to interpret intraoperative events and derive an intraoperative situation from these. To achieve a modular system architecture, it is desirable to de-couple the SRS from other system components. This leads to the need of an interface between such an SRS and context-aware systems (CAS). This work aims to provide an open standardized interface to enable loose coupling of the SRS with varying CAS to allow vendor-independent device orchestrations.
Methods
A requirements analysis investigated limiting factors that currently prevent the integration of CAS in today's ORs. These elicited requirements enabled the selection of a suitable base architecture. We examined how to specify this architecture with the constraints of an interoperability standard. The resulting middleware was integrated into a prototypic SRS and our system for intraoperative support, the OR-Pad, as exemplary CAS for evaluating whether our solution can enable context-aware assistance during simulated orthopedical interventions.
Results
The emerging Service-oriented Device Connectivity (SDC) standard series was selected to specify and implement a middleware for providing the interpreted contextual information while the SRS and CAS are loosely coupled. The results were verified within a proof of concept study using the OR-Pad demonstration scenario. The fulfillment of the CAS’ requirements to act context-aware, conformity to the SDC standard series, and the effort for integrating the middleware in individual systems were evaluated. The semantically unambiguous encoding of contextual information depends on the further standardization process of the SDC nomenclature. The discussion of the validity of these results proved the applicability and transferability of the middleware.
Conclusion
The specified and implemented SDC-based middleware shows the feasibility of loose coupling an SRS with unknown CAS to realize context-aware assistance in the OR.
Purpose
Artificial intelligence (AI), in particular deep neural networks, has achieved remarkable results for medical image analysis in several applications. Yet the lack of explainability of deep neural models is considered the principal restriction before applying these methods in clinical practice.
Methods
In this study, we propose a NeuroXAI framework for explainable AI of deep learning networks to increase the trust of medical experts. NeuroXAI implements seven state-of-the-art explanation methods providing visualization maps to help make deep learning models transparent.
Results
NeuroXAI has been applied to two applications of the most widely investigated problems in brain imaging analysis, i.e., image classification and segmentation using magnetic resonance (MR) modality. Visual attention maps of multiple XAI methods have been generated and compared for both applications. Another experiment demonstrated that NeuroXAI can provide information flow visualization on internal layers of a segmentation CNN.
Conclusion
Due to its open architecture, ease of implementation, and scalability to new XAI methods, NeuroXAI could be utilized to assist radiologists and medical professionals in the detection and diagnosis of brain tumors in the clinical routine of cancer patients. The code of NeuroXAI is publicly accessible at https://github.com/razeineldin/NeuroXAI.
In our initial DaMoN paper, we set out the goal to revisit the results of “Starring into the Abyss [...] of Concurrency Control with [1000] Cores” (Yu in Proc. VLDB Endow 8: 209-220, 2014). Against their assumption, today we do not see single-socket CPUs with 1000 cores. Instead, multi-socket hardware is prevalent today and in fact offers over 1000 cores. Hence, we evaluated concurrency control (CC) schemes on a real (Intel-based) multi-socket platform. To our surprise, we made interesting findings opposing results of the original analysis that we discussed in our initial DaMoN paper. In this paper, we further broaden our analysis, detailing the effect of hardware and workload characteristics via additional real hardware platforms (IBM Power8 and 9) and the full TPC-C transaction mix. Among others, we identified clear connections between the performance of the CC schemes and hardware characteristics, especially concerning NUMA and CPU cache. Overall, we conclude that no CC scheme can efficiently make use of large multi-socket hardware in a robust manner and suggest several directions on how CC schemes and overall OLTP DBMS should evolve in future.
Recognition of sleep and wake states is one of the relevant parts of sleep analysis. Performing this measurement in a contactless way increases comfort for the users. We present an approach evaluating only movement and respiratory signals to achieve recognition, which can be measured non-obtrusively. The algorithm is based on multinomial logistic regression and analyses features extracted out of mentioned above signals. These features were identified and developed after performing fundamental research on characteristics of vital signals during sleep. The achieved accuracy of 87% with the Cohen’s kappa of 0.40 demonstrates the appropriateness of a chosen method and encourages continuing research on this topic.
One of the key challenges for automatic assistance is the support of actors in the operating room depending on the status of the procedure. Therefore, context information collected in the operating room is used to gain knowledge about the current situation. In literature, solutions already exist for specific use cases, but it is doubtful to what extent these approaches can be transferred to other conditions. We conducted a comprehensive literature research on existing situation recognition systems for the intraoperative area, covering 274 articles and 95 cross-references published between 2010 and 2019. We contrasted and compared 58 identified approaches based on defined aspects such as used sensor data or application area. In addition, we discussed applicability and transferability. Most of the papers focus on video data for recognizing situations within laparoscopic and cataract surgeries. Not all of the approaches can be used online for real-time recognition. Using different methods, good results with recognition accuracies above 90% could be achieved. Overall, transferability is less addressed. The applicability of approaches to other circumstances seems to be possible to a limited extent. Future research should place a stronger focus on adaptability. The literature review shows differences within existing approaches for situation recognition and outlines research trends. Applicability and transferability to other conditions are less addressed in current work.
Public transport maps are typically designed in a way to support route finding tasks for passengers, while they also provide an overview about stations, metro lines, and city-specific attractions. Most of those maps are designed as a static representation, maybe placed in a metro station or printed in a travel guide. In this paper, we describe a dynamic, interactive public transport map visualization enhanced by additional views for the dynamic passenger data on different levels of temporal granularity. Moreover, we also allow extra statistical information in form of density plots, calendar-based visualizations, and line graphs. All this information is linked to the contextual metro map to give a viewer insights into the relations between time points and typical routes taken by the passengers. We also integrated a graph-based view on user-selected routes, a way to interactively compare those routes, an attribute- and property-driven automatic computation of specific routes for one map as well as for all available maps in our repertoire, and finally, also the most important sights in each city are included as extra information to include in a user-selected route. We illustrate the usefulness of our interactive visualization and map navigation system by applying it to the railway system of Hamburg in Germany while also taking into account the extra passenger data. As another indication for the usefulness of the interactively enhanced metro maps we conducted a controlled user experiment with 20 participants.
Das Buch führt in die Grundlagen der Softwaretechnik ein. Dabei liegt sein Fokus auf der systematischen und modellbasierten Software- und Systementwicklung aber auch auf dem Einsatz agiler Methoden. Die Autoren legen besonderen Wert auf die gleichwertige Behandlung praktischer Aspekte und zugrundeliegender Theorien, was das Buch als Fach- und Lehrbuch gleichermaßen geeignet macht. Die Softwaretechnik wird im Rahmen eines systematischen Frameworks umfassend beschrieben. Ausgewählte und aufeinander abgestimmte Konzepte und Methoden werden durchgängig und integriert dargestellt.