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Menopause is the permanent cessation of menstruation occurring naturally in women's aging. The most frequent symptoms associated with menopausal phases are mucosal dryness, increased weight and body fat, and changes in sleep patterns. Oral symptoms in menopause derived from saliva flow reduction can lead to dry mouth, ulcers, and alterations of taste and swallowing patterns. However, the oral health phenotype of postmenopausal women has not been characterized. The aim of the study was to determine postmenopausal women's oral phenotype, including medical history, lifestyle, and oral assessment through artificial intelligence algorithms. We enrolled 100 postmenopausal women attending the Dental School of the University of Seville were included in the study. We collected an extensive questionnaire, including lifestyle, medication, and medical history. We used an unsupervised k-means algorithm to cluster the data following standard features for data analysis. Our results showed the main oral symptoms in our postmenopausal cohort were reduced salivary flow and periodontal disease. Relying on the classical assessment of the collected data, we might have a biased evaluation of postmenopausal women. Then, we used artificial intelligence analysis to evaluate our data obtaining the main features and providing a reduced feature defining the oral health phenotype. We found 6 clusters with similar features, including medication affecting salivation or smoking as essential features to obtain different phenotypes. Thus, we could obtain main features considering differential oral health phenotypes of postmenopausal women with an integrative approach providing new tools to assess the women in the dental clinic.
Acting like a startup - using corporate startup structures to manage the digital transformation
(2023)
Digital transformation is proving to be a significant challenge for firms and companies when it comes to maintaining their market position. It is evident that many companies are struggling to find their particular way through this transformation. A corporate startup structure is one way to find a suitable solution quickly. Therefore, we are presenting a model for corporate startup activities, which we will instantiate in an appropriate tool to support the management of corporate startups by their parent firms. We have derived the first requirements and design principles from a comprehensive problem analysis and literature study. In addition to this,we are presenting a first artifact, which should realize the design principles by implementing a practical tool. Forming a cooperation with an automotive firm has enabled us to gain access to real-world data for the design and evaluation of the artifact.
Modern component-based architectural styles, e.g., microservices, enable developing the components independently from each other. However, this independence can result in problems when it comes to managing issues, such as bugs, as developer teams can freely choose their technology stacks, such as issue management systems (IMSs), e.g., Jira, GitHub, or Redmine. In the case of a microservice architecture, if an issue of a downstream microservice depends on an issue of an upstream microservice, this must be both identified and communicated, and the downstream service’s issues should link to its causing issue. However, agile project management today requires efficient communication, which is why more and more teams are communicating through comments in the issues themselves. Unfortunately, IMSs are not integrated with each other, thus, semantically linking these issues is not supported, and identifying such issue dependencies from different IMSs is time-consuming and requires manual searching in multiple IMS technologies. This results in many context switches and prevents developers from being focused and getting things done. Therefore, in this paper, we present a concept for seamlessly integrating different IMS technologies into each other and providing a better architectural context. The concept is based on augmenting the websites of issue management systems through a browser extension. We validate the approach with a prototypical implementation for the Chrome browser. For evaluation, we conducted expert interviews, which approved that the presented approach provides significant advantages for managing issues of agile microservice architectures.
Application systems often need to be deployed in different variants if requirements that influence their implementation, hosting, and configuration differ between customers. Therefore, deployment technologies, such as Ansible or Terraform, support a certain degree of variability modeling. Besides, modern application systems typically consist of various software components deployed using multiple deployment technologies that only support their proprietary, non-interoperable variability modeling concepts. The Variable Deployment Metamodel (VDMM) manages the deployment variability across heterogeneous deployment technologies based on a single variable deployment model. However, VDMM currently only supports modeling conditional components and their relations which is sometimes too coarse-grained since it requires modeling entire components, including their implementation and deployment configuration for each different component variant. Therefore, we extend VDMM by a more fine-grained approach for managing the variability of component implementations and their deployment configurations, e.g., if a cheap version of a SaaS deployment provides only a community edition of the software and not the enterprise edition, which has additional analytical reporting functionalities built-in. We show that our extended VDMM can be used to realize variable deployments across different individual deployment technologies using a case study and our prototype OpenTOSCA Vintner.
The basis for developing future products in the automotive industry is finding creative and innovative solutions. Ideas can be found by means of creativity methods that support product developers throughout the creative process. Product developers are provided with a variety of different and new methods. This leads to a “method jungle” in which it is difficult for product developers to find the most suitable path. The successful use of methods in product development goes hand in hand with the acceptance and implementation of the methods. Despite the added value, only a low use is observed in the development process. The field of Creativity Support Tools also offers a wide variety of different tools that support the creativity process. Although a chasm exists between the many CSTs that are developed and what creative practitioners actually use. Therefore, previous studies iteratively developed a user-centered tool called “IDEA” that tries to provide a tool that responds to users' needs. The question arises how the developed tool IDEA performs in “real life setting” regarding its UX and usability as well as the creativity method acceptance and level of mental workload.
In the era of digital transformation, the notion of software quality transcends its traditional boundaries, necessitating an expansion to encompass the realms of value creation for customers and the business. Merely optimizing technical aspects of software quality can result in diminishing returns. Product discovery techniques can be seen as a powerful mechanism for crafting products that align with an expanded concept of quality - one that incorporates value creation. Previous research has shown that companies struggle to determine appropriate product discovery techniques for generating, validating, and prioritizing ideas for new products or features to ensure they meet the needs and desires of the customers and the business. For this reason, we conducted a grey literature review to identify various techniques for product discovery. First, the article provides an overview of different techniques and assesses how frequently they are mentioned in the literature review. Second, we mapped these techniques to an existing product discovery process from previous research to provide concrete guidelines for establishing product discovery in their organizations. The analysis shows, among other things, the increasing importance of techniques to structure the problem exploration process and the product strategy process. The results are interpreted regarding the importance of the techniques to practical applications and recognizable trends.
Transforming our food system is important to achieving global climate neutrality and food security. Germany has set a national target of reaching a 30% share in organic farming to support the goal. When looking at the transformation process from conventional to organic farming, it becomes apparent that measures need to be taken to reach this anticipated goal. A particular emphasis of this work is placed on finding a digital solution and process improvements to ensure longevity and efficiency. Interviews with actors along the farm-to-fork value chain were conducted to identify central barriers and drivers of organic transformation. The results of the interviews show firstly, that three subsystems need to be distinguished when talking about the farm-to-fork value chain: (1) farmers, (2) intermediaries, and (3) the canteen system. Although all three subsystems can be combined to form a coherent value chain, they rarely act and communicate beyond the boundaries of their subsystem. Secondly, we were able to allocate primary barriers and drivers to each of the subsystems, highlighting the need to include all three in the transformation process and aim for a comprehensive digital solution. This work explores the potential of a network-based platform to improve the current practice of rigid and strictly hierarchical value chains. We focus on deriving user requirements from the interviews to describe the necessary functionality of the platform to address the identified barriers and exploit existing drivers.
Applications often need to be deployed in different variants due to different customer requirements. However, since modern applications often need to be deployed using multiple deployment technologies in combination, such as Ansible and Terraform, the deployment variability must be considered in a holistic way. To tackle this, we previously developed Variability4TOSCA and the prototype OpenTOSCA Vintner, which is a TOSCA preprocessing and management layer that implements Variability4TOSCA. In this demonstration, we present a detailed case study that shows how to model a deployment using Variability4TOSCA, how to resolve the variability using Vintner, and how the result can be deployed.
Gamification has been increasingly applied to software engineering education in the past. The approaches vary from applying game elements on a conceptual phase in the course to using specific tools to engage the students more and support their learning goals. However, existing tools usually have game elements, such as quizzes or challenges, but do not provide a more computer game-like experience. Therefore, we try to raise the level of gamified learning experience to another level by proposing Gamify-IT. Gamify-IT is a Unity- and web-based game platform intended to help students learn software engineering. It follows an immersive role-play game characteristic where the students explore a world, find and solve minigames and clear dungeons with SE tasks. Lecturers can configure the worlds, e.g., to add content hints. Furthermore, they can add and configure minigames and dungeons to include exercises in a fully gamified way. Thereby, they customize their course in Gamify-IT to adapt the world very precisely to other materials such as lectures or exercises. Results of an evaluation of our initial prototype show that (i) students like to engage with the platform, (ii) students are motivated to learn when using Gamify-IT, and (iii) the minigames support students in understanding the learning objectives.
Intelligent Tutoring Systems (ITSs) are increasingly used in modern education to automatically give students individual feedback on their performance. The advantage for students is fast individual feedback on their answers to asked questions, while lecturers benefit from considerable time savings and easy delivery of educational material. Of course, it is important that the provided feedback is as effective as direct feedback from the lecturer. However, in digital teaching, lecturers cannot assess the student’s knowledge precisely but can only provide information on which questions were answered correctly and incorrectly. Therefore, this paper presents a concept for integrating ITS elements into the gamified e-learning platform IT-REX so that the feedback quality can be improved to support students in the best possible way.
This research evaluates current measurement scales for ambidexterity and proposes a new approach for the measurement of this important construct. We argue that current measurement approaches may be unsuitable to capture the concept of ambidexterity. Through a systematic scale development process, we derive a measurement scale with dual items that simultaneously refer to both dimensions, exploitation and exploration, thus reflecting the true nature of ambidexterity. An extensive pre-test with 39 executives suggests that our scale is suitable for capturing ambidexterity. Our measurement model enhances conceptual clarity of ambidexterity and can serve as a base for future investigations of the concept.
Organizational agility may be an antidote against threats from volatile, uncertain, complex, or ambiguous corporate environments. While agility has been extensively examined in manufacturing enterprises, comparably less is known about agility in knowledge-intensive organizations. As results may not be transferable, there is still some confusion about how agility in knowledge-intensive organizations can be characterized, what factors facilitate its development, what its organizational effects are, and what environmental conditions favor these effects. This study closes these gaps by presenting a systematic literature review on agility in knowledge-intensive organizations. A systematic literature search led to a sample of 37 relevant papers for our review. Integrating the knowledge-based view and a dynamic capabilities perspective, we (1) present different relevant conceptualizations of organizational agility, (2) discuss relevant knowledge management-related as well as information technology-related capabilities that support the development of organizational agility, and (3) shed light on the moderating role of environmental conditions in enhancing organizational agility and its effect on organizational performance. This academic paper adds value to theory by synthesizing existing research on agility in knowledge-intensive organizations. It furthermore may serve as a map for closing research gaps by proposing an extensive agenda for future research. Our study expands existing literature reviews on agility with its specific focus on a knowledge-intensive context and its integration of the research streams of knowledge management capabilities as well as information technology capabilities. It integrates relevant organizational knowledge management practices and the use of knowledge management systems to ensure superior performance effects. Our study can serve as a base for future examinations of organizational agility by illustrating fruitful topics for further examination as well as open questions. It may also provide value to practitioners by showing what factors favor the development of agility in knowledge-intensive organizations and what organizational effects can be achieved under which conditions.
Knowledge-intensive organizations primarily rely on knowledge and expertise as key strategic resources. In light of economic, social, and health-related crises in recent years, such organizations increasingly need to operate in dynamic environments. However, examinations on dynamic capabilities specifically in knowledge-intensive organizations remain scarce. This is remarkable given the role that knowledge holds as an economic resource in developed countries. To provide an explanation of how knowledge-intensive organizations can prevail among competitors under dynamic conditions, the authors integrate two literature streams in a knowledge-intensive context: the knowledge-based view and the dynamic capabilities approach. The knowledge-based view focuses on the nature of organizational knowledge as a critical resource and illustrates specific properties of knowledge in contrast to traditional means of labor such as capital. The dynamic capabilities approach on the other hand is about a firm's ability to integrate, build, and reconfigure internal and external resources and can be drawn on to explain organizational success through adaptation to dynamic contexts. In this conceptual study, the authors propose a research model linking knowledge processes to organizational performance through two different paths: (1) Operational capabilities permit organizations to make their living in the present and refer to efficiency. (2) Dynamic capabilities allow organizations to change their resource base and, therefore, enable their long-term survival in dynamic environments by focusing on effectiveness. Additionally, the authors hypothesize a moderating effect of environmental dynamics on the relationship between dynamic capabilities and performance. The study offers a comprehensive overview on the interplay between dynamic capabilities and the knowledge-based view, offering valuable insights for both researchers and practitioners in the field.
Human pose estimation (HPE) is integral to scene understanding in numerous safety-critical domains involving human-machine interaction, such as autonomous driving or semi-automated work environments. Avoiding costly mistakes is synonymous with anticipating failure in model predictions, which necessitates meta-judgments on the accuracy of the applied models. Here, we propose a straightforward human pose regression framework to examine the behavior of two established methods for simultaneous aleatoric and epistemic uncertainty estimation: maximum a-posteriori (MAP) estimation with Monte-Carlo variational inference and deep evidential regression (DER). First, we evaluate both approaches on the quality of their predicted variances and whether these truly capture the expected model error. The initial assessment indicates that both methods exhibit the overconfidence issue common in deep probabilistic models. This observation motivates our implementation of an additional recalibration step to extract reliable confidence intervals. We then take a closer look at deep evidential regression, which, to our knowledge, is applied comprehensively for the first time to the HPE problem. Experimental results indicate that DER behaves as expected in challenging and adverse conditions commonly occurring in HPE and that the predicted uncertainties match their purported aleatoric and epistemic sources. Notably, DER achieves smooth uncertainty estimates without the need for a costly sampling step, making it an attractive candidate for uncertainty estimation on resource-limited platforms.
Smart cities are considered data factories that generate an enormous amount of data from various sources. In fact data is the backbone of any smart services. Therefore, the strategic beneficial handling of this digital capital is crucial for cities. Some smart city pioneers have already written down their approach to data in the form of data strategies, but what should a city's data strategy include, and how can the goals and measures defined in the strategies be operationalized? This paper addresses these questions by looking closely at the data strategies of cities in Germany and the top three countries in the EU Digital Economy and Society Index. The in-depth analysis of 8 city data strategies has yielded 11 dimensions that cities should consider in their data strategy. These are relevance of data, principles, methods, data sharing, technology, data culture, data ethics, organizational structure, data security and privacy, collaborations, data literacy. In addition, data governance is a concept to put these 11 strategic dimensions into practice through standardization measures, training programs, and defining roles and responsibilities by developing a data catalog.
Platforms feature increasingly complex architectures with regard to interconnecting with other digital platforms as well as with a variety of devices and services. This development also impacts the structure of digital platform ecosystems and forces providers of these services, devices, and services to incorporate this complexity in their decision-making. To contribute to the existing body of knowledge on measuring ecosystem complexity, the present research proposes two key artefacts based on ecosystem intelligence: On the one hand, complementarity graphs represent ecosystems with an ecosystem's functional modules as vertices and complementarities as edges. The nodes carry information about the category membership of the module. On the other hand, a process is suggested that can collect important information for ecosystem intelligence using proxies and web scraping. Our approach allows replacing data, which today is largely unavailable due to competitive reasons. We demonstrated the use of the artefacts in category-oriented complementarity maps that aggregate the information from complementarity graphs and support decision-making. They show which combination of module categories creates strong and weak complementarities. The paper evaluates complementarity maps and the data collection process by creating category-oriented complementarity graphs on the Alexa skill ecosystem and concludes with a call to pursue more research based on functional ecosystem intelligence.
Measuring cardiorespiratory parameters in sleep, using non-contact sensors and the Ballistocardiography technique has received much attention due to the low-cost, unobtrusive, and non-invasive method. Designing a user-friendly, simple-to-use, and easy-to-deployment preserving less error-prone remains open and challenging due to the complex morphology of the signal. In this work, using four forcesensitive resistor sensors, we conducted a study by designing four distributions of sensors, in order to simplify the complexity of the system by identifying the region of interest for heartbeat and respiration measurement. The sensors are deployed under the mattress and attached to the bed frame without any interference with the subjects. The four distributions are combined in two linear horizontal, one linear vertical, and one square, covering the influencing region in cardiorespiratory activities. We recruited 4 subjects and acquired data in four regular sleeping positions, each for a duration of 80 seconds. The signal processing was performed using discrete wavelet transform bior 3.9 and smooth level of 4 as well as bandpass filtering. The results indicate that we have achieved the mean absolute error of 2.35 and 4.34 for respiration and heartbeat, respectively. The results recommend the efficiency of a triangleshaped structure of three sensors for measuring heartbeat and respiration parameters in all four regular sleeping positions.
Large critical systems, such as those created in the space domain, are usually developed by a large number of organizations and, furthermore, they have to comply with standards. Yet, the different stakeholders often do not have a common understanding of the needed quality of requirements specifications. Achieving such a common understanding is a laborious process that is currently not sufficiently supported. Moreover, such a common understanding must be aligned with the standards. In this paper, we present an approach that can be used to align the different stakeholder perceptions regarding the quality of requirements specifications. Existing quality models for requirements specifications are analyzed for equivalences, and transferred into a common representation, the so-called Aligned Quality Map (AQM). Furthermore, a process is defined that supports the alignment of different stakeholder perspectives with regard to the quality of requirements specifications using AQM, which is validated in a case study in the context of European space projects. AQM has been created and populated with an initial set of quality models. It is designed in such way that it can be extended to include further quality models. The case study has shown that an alignment of different stakeholder perspectives and the quality model of the European Cooperation for Space Standardization using AQM is feasible. The approach allows for aligning different stakeholder perspectives for a common understanding of the quality of requirements specifications in the context of standards. Furthermore, AQM supports the assessment of requirements specifications.
In the context of digital transformation, having a data-driven organizational culture has been recognized as an important factor for data analytics capabilities, innovativeness and competitive advantage of firms. However, the current literature on data-driven culture (DDC) is fragmented, lacking both a synthesis of findings and a theoretical foundation. Therefore, the aim of this work has been to develop a comprehensive framework for understanding DDC and the mechanisms that can be used to embed such a culture in organizations as well as structuring prior dispersed findings on the topic. Based on the foundation of organizational culture theory, we employed a Design Science Research (DSR) approach using a systematic literature review and expert interviews to build and evaluate a transformation-oriented framework. This research contributes to knowledge by synthesizing previously dispersed knowledge in a holistic framework, as well as, by providing a conceptual framework to guide the transformation towards a DDC.
The performance and scalability of modern data-intensive systems are limited by massive data movement of growing datasets across the whole memory hierarchy to the CPUs. Such traditional processor-centric DBMS architectures are bandwidth- and latency-bound. Processing-in-Memory (PIM) designs seek to overcome these limitations by integrating memory and processing functionality on the same chip. PIM targets near- or in-memory data processing, leveraging the greater in-situ parallelism and bandwidth.
In this paper, we introduce pimDB and provide an initial comparison of processor-centric and PIM-DBMS approaches under different aspects, such as scalability and parallelism, cache-awareness, or PIM-specific compute/bandwidth tradeoffs. The evaluation is performed end-to-end on a real PIM hardware system from UPMEM.
Software development teams have to face stress caused by deadlines, staff turnover, or individual differences in commitment, expertise, and time zones. While students are typically taught the theory of software project management, their exposure to such stress factors is usually limited. However, preparing students for the stress they will have to endure once they work in project teams is important for their own sake, as well as for the sake of team performance in the face of stress. Team performance has been linked to the diversity of software development teams, but little is known about how diversity influences the stress experienced in teams. In order to shed light on this aspect, we provided students with the opportunity to self-experience the basics of project management in self-organizing teams, and studied the impact of six diversity dimensions on team performance, coping with stressors, and positive perceived learning effects. Three controlled experiments at two universities with a total of 65 participants suggest that the social background impacts the perceived stressors the most, while age and work experience have the highest impact on perceived learnings. Most diversity dimensions have a medium correlation with the quality of work, yet no significant relation to the team performance. This lays the foundation to improve students’ training for software engineering teamwork based on their diversity-related needs and to create diversity-sensitive awareness among educators, employers and researchers.
For large-scale processes as implemented in organizations that develop software in regulated domains, comprehensive software process models are implemented, e.g., for compliance requirements. Creating and evolving such processes is demanding and requires software engineers having substantial modeling skills to create consistent and certifiable processes. While teaching process engineering to students, we observed issues in providing and explaining models. In this paper, we present an exploratory study in which we aim to shed light on the challenges students face when it comes to modeling. Our findings show that students are capable of doing basic modeling tasks, yet, fail in utilizing models correctly. We conclude that the required skills, notably abstraction and solution development, are underdeveloped due to missing practice and routine. Since modeling is key to many software engineering disciplines, we advocate for intensifying modeling activities in teaching.
Near-Data Processing (NDP) is a key computing paradigm for reducing the ever growing time and energy costs of data transport versus computations. With their flexibility, FPGAs are an especially suitable compute element for NDP scenarios. Even more promising is the exploitation of novel and future non-volatile memory (NVM) technologies for NDP, which aim to achieve DRAM-like latencies and throughputs, while providing large capacity non-volatile storage.
Experimentation in using FPGAs in such NVM-NDP scenarios has been hindered, though, by the fact that the NVM devices/FPGA boards are still very rare and/or expensive. It thus becomes useful to emulate the access characteristics of current and future NVMs using off-the-shelf DRAMs. If such emulation is sufficiently accurate, the resulting FPGA-based NDP computing elements can be used for actual full-stack hardware/software benchmarking, e.g., when employed to accelerate a database.
For this use, we present NVMulator, an open-source easy-to-use hardware emulation module that can be seamlessly inserted between the NDP processing elements on the FPGA and a conventional DRAM-based memory system. We demonstrate that, with suitable parametrization, the emulated NVM can come very close to the performance characteristics of actual NVM technologies, specifically Intel Optane. We achieve 0.62% and 1.7% accuracy for cache line sized accesses for read and write operations, while utilizing only 0.54% of LUT logic resources on a Xilinx/AMD AU280 UltraScale+ FPGA board. We consider both file-system as well as database access patterns, examining the operation of the RocksDB database when running on real or emulated Optane-technology memories.
OpenAPI, WADL, RAML, and API Blueprint are popular formats for documenting Web APIs. Although these formats are in general both human and machine-readable, only the part of the format describing the syntax of a Web API is machine-understandable. Descriptions, which explain the meaning and purpose of Web API elements, are embedded as natural language text snippets into documents and target human readers but not machines. To enable machines to read and process these state-of-practice Web API documentation, we propose a Transformer model that solves the generic task of identifying a Web API element within a syntax structure that matches a natural language query. For our first prototype, we focus on the Web API integration task of matching output with input parameters and fined-tuned a pre-trained CodeBERT model to the downstream task of question answering with samples from 2,321 OpenAPI documentation. We formulate the original question answering problem as a multiple choice task: given a semantic natural language description of an output parameter (question) and the syntax of the input schema (paragraph), the model chooses the input parameter (answer) in the schema that best matches the description. The paper describes the data preparation, tokenization, and fine-tuning process as well as discusses possible applications of our model as part of a recommender system. Furthermore, we evaluate the generalizability and the robustness of our fine-tuned model, with the result that it achieves an accuracy of 81.46% correctly chosen parameters.
The relevance of Robotic Process Automation (RPA) has increased over the last few years. Combining RPA with Artificial Intelligence (AI) can further enhance the business value of the technology. The aim of this research was to analyze applications, terminology, benefits, and challenges of combining the two technologies. A total of 60 articles were analyzed in a systematic literature review to evaluate the aforementioned areas. The results show that by adding AI, RPA applications can be used in more complex contexts, it is possible to minimize the human factor during the development process, and AI-based decision-making can be integrated into RPA routines. This paper also presents a current overview of the used terminology. Moreover, it shows that by integrating AI, some unseen challenges in RPA projects can emerge, but also a lot of new benefits will come along with it. Based on the outcome, it is concluded that the topic offers a lot of potential, but further research and development is required. The result of this study help researches to gain an overview of the state-of-the-art in combining RPA and AI.
What might the attendee be able to do after being in your session?
Our work shows how to connect intra-operative devices via IEEE 11073 Service-oriented Device Connectivity (SDC).
Description of the Problem or Gap
Standardized device communication is essential for interoperability, availability of device data, and therefore for the intelligent operating room (OR) and arising solutions. The SDC standard was developed to make information from medical devices available in a uniform manner and enable interoperability. Existing devices are rarely SDC-capable and need interfaces to be interoperable via SDC.
Methods: What did you do to address the problem or gap?
We conceived an SDC-based architecture consisting of a service provider and service consumer. In our concept, the service provider is connected to the medical device and capable to translate the proprietary protocol of the device into SDC and vice versa. The service consumer is used to request or send information via the SDC protocol to the service provider and can function as a uniform bidirectional interface (e.g. for displaying or controlling). This concept was exemplarily demonstrated with the patient monitor MX800 of Philips to retrieve the device data (e.g. vital parameters) via SDC and partly for the operating light marLED X of KLS Martin Group.
Results: What was the outcome(s) of what you did to address the problem or gap?
The patient monitor MX800 was connected to a Raspberry Pi (RPi) via LAN, on which the service provider is running. The python script on the RPi establishes a connection to the monitor and translates incoming and outgoing messages from the proprietary protocol to SDC and vice versa to/from the service consumer. The service consumer is running on a laptop and acts as a simulation for different kinds of systems that want to get vital parameters or other information from the patient monitor. The operating light marLED X was connected to an RPi via USB-to-RS232. A python script on the RPi establishes a connection to the light and makes it possible via proprietary commands to get information of the light (e.g. status) and to control it (e.g. toggle the light, increment the intensity). A translation to SDC is not integrated yet.
Discussion of Results
Our practical implementation shows that medical devices can be accessed via external connections to get device data and control the device via commands. The example SDC implementation of the patient monitor MX800 makes it possible to request its data via the standardized communication protocol SDC. This is also possible for the operating light marLED X if its proprietary protocol is analyzed to be translatable to/from SDC. This would allow to control the device from an external system, or automatically depending on the status of the ongoing procedure. The advantage is, that existing intra-operative devices can be extended by a service provider which is capable of translating the proprietary protocol of the device in SDC and vice versa. This enables interoperability and an intelligent OR that, for example, is aware of all devices, their status, and data and can use this information to optimally support the surgeons and their team (e.g. provision of information, automated documentation). This interoperability allows that future innovations merely need to understand the SDC protocol instead of all vendor-dependent communication protocols.
Conclusion
Standardized device communication is essential to reach interoperability, and therefore intelligent ORs. Our contribution addresses the possibility of subsequently making medical devices SDC-capable. This may eliminate the need of understanding all the different proprietary protocols when developing new innovative solutions for the OR.
Introduction: Even if there is a standard procedure of CI surgery, especially in pediatric surgery surgical steps often differ individually due to anatomical variations, malformations or unforseen events. This is why every surgical report should be created individually, which takes time and relies on the correct memory of the surgeon. A standardized recording of intraoperative data and subsequent storage as well as text processing would therefore be desirable and provides the basis for subsequent data processing, e.g. in the context of research or quality assurance.
Method: In cooperation with Reutlingen University, we conducted a workflow analysis of the prototype of a semi-automatic checklist tool. Based on automatically generated checklists generated from BPMN models a prototype user interface was developed for an android tablet. Functions such as uploading photos and files, manual user entries, the interception of foreseeable deviations from the normal course of operations and the automatic creation of OP documentation could be implemented. The system was tested in a remote usability test on a petrous bone model.
Result: The user interface allows a simple intuitive handling, which can be well implemented in the intraoperative setting. Clinical data as well as surgical steps could be individually recorded and saved via DICOM. An automatic surgery report could be created and saved.
Summary: The use of a dynamic checklist tool facilitates the capture, storage and processing of surgical data. Further applications in clinical practice are pending.
This project aims to evaluate existing big data infrastructures for their applicability in the operating room to support medical staff with context-sensitive systems. Requirements for the system design were generated. The project compares different data mining technologies, interfaces, and software system infrastructures with a focus on their usefulness in the peri-operative setting. The lambda architecture was chosen for the proposed system design, which will provide data for both postoperative analysis and real-time support during surgery.
Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to the variety of scanners and imaging protocols. Over the last years, the BraTS Challenge has provided a large number of multi-institutional MRI scans as a benchmark for glioma segmentation algorithms. This paper describes our contribution to the BraTS 2022 Continuous Evaluation challenge. We propose a new ensemble of multiple deep learning frameworks namely, DeepSeg, nnU-Net, and DeepSCAN for automatic glioma boundaries detection in pre-operative MRI. It is worth noting that our ensemble models took first place in the final evaluation on the BraTS testing dataset with Dice scores of 0.9294, 0.8788, and 0.8803, and Hausdorf distance of 5.23, 13.54, and 12.05, for the whole tumor, tumor core, and enhancing tumor, respectively. Furthermore, the proposed ensemble method ranked first in the final ranking on another unseen test dataset, namely Sub-Saharan Africa dataset, achieving mean Dice scores of 0.9737, 0.9593, and 0.9022, and HD95 of 2.66, 1.72, 3.32 for the whole tumor, tumor core, and enhancing tumor, respectively.
Enterprises and societies currently face essential challenges, and digital transformation can contribute to their resolution. Enterprise architecture (EA) is useful for promoting digital transformation in global companies and information societies covering ecosystem partners. The advancement of new business models can be promoted with digital platforms and architectures for Industry 4.0 and Society 5.0. Therefore, products from the sector of healthcare, manufacturing and energy, etc. can increase in value. The adaptive integrated digital architecture framework (AIDAF) for Industry 4.0 and the design thinking approach is expected to promote and implement the digital platforms and digital products for healthcare, manufacturing and energy communities more efficiently. In this paper, we propose various cases of digital transformation where digital platforms and products are designed and evaluated for digital IT, digital manufacturing and digital healthcare with Industry 4.0 and Society 5.0. The vision of AIDAF applications to perform digital transformation in global companies is explained and referenced, extended toward the digitalized ecosystems such as Society 5.0 and Industry 4.0.
Mobile monitoring of outpatients during cancer therapy becomes possible through technological advancements. This study leveraged a new remote patient monitoring app for in-between systemic therapy sessions. Patients’ evaluation showed that the handling is feasible. Clinical implementation must consider an adaptive development cycle for reliable operations.
Current advances in Artificial Intelligence (AI) combined with other digitalization efforts are changing the role of technology in service ecosystems. Human-centered intelligent systems and services are the target of many current digitalization efforts and part of a massive digital transformation based on digital technologies. Artificial intelligence, in particular, is having a powerful impact on new opportunities for shared value creation and the development of smart service ecosystems. Motivated by experiences and observations from digitalization projects, this paper presents new methodological experiences from academia and practice on a joint view of digital strategy and architecture of intelligent service ecosystems and explores the impact of digitalization based on real case study results. Digital enterprise architecture models serve as an integral representation of business, information, and technology perspectives of intelligent service-based enterprise systems to support management and development. This paper focuses on the novel aspect of closely aligned digital strategy and architecture models for intelligent service ecosystems and highlights the fundamental business mechanism of AI-based value creation, the corresponding digital architecture, and management models. We present key strategy-oriented architecture model perspectives for intelligent systems.
In today’s education, healthcare, and manufacturing sectors, organizations and information societies are discussing new enhancements to corporate structure and process efficiency using digital platforms. These enhancements can be achieved using digital tools. Industry 5.0 and Society 5.0 give several potentials for businesses to enhance the adaptability and efficacy of their industrial processes, paving the door for developing new business models facilitated by digital platforms. Society 5.0 can contribute to a super-intelligent society that includes the healthcare industry. In the past decade, the Internet of Things, Big Data Analytics, Neural Networks, Deep Learning, and Artificial Intelligence (AI) have revolutionized our approach to various job sectors, from manufacturing and finance to consumer products. AI is developing quickly and efficiently. We have heard of the latest artificial intelligence chatbot, ChatGPT. OpenAI created this, which has taken the internet by storm. We tested the effectiveness of a considerable language model referred to as ChatGPT on four critical questions concerning “Society 5.0”, “Healthcare 5.0”, “Industry,” and “Future Education” from the perspectives of Age 5.0.
Non-fungible tokens (NFTs) are unique digital assets that have recently gained significant popularity, particularly in the digital art sector. The success of NFTs and other blockchain-based innovations depends on their ac-acceptance and use by consumers. This study aims to understand the impact of moral values on the acceptance of NFTs. Based on a quantitative survey with over 800 complete responses, the analysis shows that moral aspects of NFTs are indeed important for potential users. However, there is an attitude-behavior gap, as the positive impact of moral values on the intention to use NFTs is not reflected in the actual current usage of NFTs by the respondents. This study contributes to knowledge by providing new empirical data on the acceptance of NFTs and highlighting the role of moral values on the acceptance decision.
Digital twins deployed in production are important in practice and interesting for research. Currently, mostly structured data coming from e.g., sensors and timestamps of related stations, are integrated into Digital Twins. However, semi- and unstructured data are also important to display the current status of a digital twin (e.g., of a machinery or produced good). Process Mining and Text Mining in combination can be used to support the use of log file data to understand the current state of the process as well as highlight issues. Therefore, issue related reactions can be taken more quickly, targeted and cost oriented. Applying a design science research approach; here a prototype as an artefact based on derived requirements is developed. This prototype helps to understand and to clarify the possibilities of Process Mining and Text Mining based on log data for production related Digital Twins. Contributions for practice and research are described. Furthermore, limitations of the research and future opportunities are pointed out.
The volume includes papers presented at the International KES Conference on Human Centred Intelligent Systems 2023 (KES HCIS 2023), held in Rome, Italy on June 14–16, 2023. This book highlights new trends and challenges in intelligent systems, which play an important part in the digital transformation of many areas of science and practice. It includes papers offering a deeper understanding of the human-centred perspective on artificial intelligence, of intelligent value co-creation, ethics, value-oriented digital models, transparency, and intelligent digital architectures and engineering to support digital services and intelligent systems, the transformation of structures in digital businesses and intelligent systems based on human practices, as well as the study of interaction and the co-adaptation of humans and systems.
Motivation
In order to enable context-aware behavior of surgical assistance systems, the acquisition of various information about the current intraoperative situation is crucial. To achieve this, the complex task of situation recognition can be delegated to a specialized system. Consequently, a standardized interface is required for the seamless transfer of the recognized contextual information to the assistance systems, enabling them to adapt accordingly.
Methods
Our group analyzed four medical interface standards to determine their suitability for exchanging intraoperative contextual information. The assessment was based on a harmonized data and service model derived from the requirements of expected context-aware use cases. The Digital Imaging and Communications in Medicine (DICOM) and IEEE 11073 for Service-oriented Device Connectivity (SDC) were identified as the most appropriate standards.
Results
We specified how DICOM Unified Procedure Steps (UPS), can be used to effectively communicate contextual information. We proposed the inclusion of attributes to formalize different granularity levels of the surgical workflow.
Conclusions
DICOM UPS SOP classes can be used for the exchange of intraoperative contextual information between a situation recognition system and surgical assistance systems. This can pave the way for vendor-independent context awareness in the OR, leading to targeted assistance of the surgical team and an improvement of the surgical workflow.
Recent work on database application development platforms has sought to include a declarative formulation of a conceptual data model in the application code, using annotations or attributes. Some recent work has used metadata to include the details of such formulations in the physical database, and this approach brings significant advantages in that the model can be enforced across a range of applications for a single database. In previous work, we have discussed the advantages for enterprise integration of typed graph data models (TGM), which can play a similar role in graphical databases, leveraging the existing support for the unified modelling language UML. Ideally, the integration of systems designed with different models, for example, graphical and relational database, should also be supported. In this work, we implement this approach, using metadata in a relational database management system (DBMS).
The Fifteenth International Conference on Advances in Databases, Knowledge, and Data Applications (DBKDA 2023), held between March 13 – 17, 2023, continued a series of international events covering a large spectrum of topics related to advances in fundamentals on databases, evolution of relation between databases and other domains, data base technologies and content processing, as well as specifics in applications domains databases.
Advances in different technologies and domains related to databases triggered substantial improvements for content processing, information indexing, and data, process and knowledge mining. The push came from Web services, artificial intelligence, and agent technologies, as well as from the generalization of the XML adoption.
High-speed communications and computations, large storage capacities, and load-balancing for distributed databases access allow new approaches for content processing with incomplete patterns, advanced ranking algorithms and advanced indexing methods.
Evolution on e-business, ehealth and telemedicine, bioinformatics, finance and marketing, geographical positioning systems put pressure on database communities to push the ‘de facto’ methods to support new requirements in terms of scalability, privacy, performance, indexing, and heterogeneity of both content and technology.
The Fourteenth International Conference on Advances in Databases, Knowledge, and Data Applications (DBKDA 2022), held between May 22 – 26, 2022, continued a series of international events covering a large spectrum of topics related to advances in fundamentals on databases, evolution of relation between databases and other domains, data base technologies and content processing, as well as specifics in applications domains databases.
Advances in different technologies and domains related to databases triggered substantial improvements for content processing, information indexing, and data, process and knowledge mining. The push came from Web services, artificial intelligence, and agent technologies, as well as from the generalization of the XML adoption.
High-speed communications and computations, large storage capacities, and load-balancing for distributed databases access allow new approaches for content processing with incomplete patterns, advanced ranking algorithms and advanced indexing methods.
Evolution on e-business, ehealth and telemedicine, bioinformatics, finance and marketing, geographical positioning systems put pressure on database communities to push the ‘de facto’ methods to support new requirements in terms of scalability, privacy, performance, indexing, and heterogeneity of both content and technology.
Purpose
Artificial intelligence (AI), in particular deep learning (DL), has achieved remarkable results for medical image analysis in several applications. Yet the lack of human-like explanations of such systems is considered the principal restriction before utilizing these methods in clinical practice (Yang, Ye, & Xia, 2022).
Methods
Explainable Artificial Intelligence (XAI) provides a human-explainable and interpretable description of the “black-box” nature of DL (Gulum, Trombley, & Kantardzic, 2021). An effective XAI diagnosis generator, namely NeuroXAI (refer to Fig. 1), has been developed to extract 3D explanations from convolutional neural networks (CNN) models of brain gliomas (Zeineldin et al., 2022). By providing visual justification maps, NeuroXAI can help make DL models transparent and thus increase the trust of medical experts.
Results
NeuroXAI has been applied to two applications of the most widely investigated problems in brain imaging analysis, i.e. image classification and segmentation using magnetic resonance imaging (MRI). Visual attention maps of multiple XAI methods have been generated and compared for both applications, which could help to provide transparency about the performance of DL systems.
Conclusion
NeuroXAI helps to understand the prediction process of 3D CNN networks for brain glioma using human-understandable explanations. Results revealed that the investigated DL models behave in a logical human-like manner and can improve the analytical process of the MRI images systematically. Due to its open architecture, ease of implementation, and scalability to new XAI methods, NeuroXAI could be utilized to assist medical professionals in the detection and diagnosis of brain tumors. NeuroXAI code is publicly accessible at https://github.com/razeineldin/NeuroXAI
Context: Companies that operate in the software-intensive business are confronted with high market dynamics, rapidly evolving technologies as well as fast-changing customer behavior. Traditional product roadmapping practices, such as fixed-time-based charts including detailed planned features, products, or services typically fail in such environments. Until now, the underlying reasons for the failure of product roadmaps in a dynamic and uncertain market environment are not widely analyzed and understood.
Objective: This paper aims to identify current challenges and pitfalls practitioners face when developing and handling product roadmaps in a dynamic and uncertain market environment.
Method: To reach our objective we conducted a grey literature review (GLR).
Results: Overall, we identified 40 relevant papers, from which we could extract 11 challenges of the application of product roadmapping in a dynamic and uncertain market environment. The analysis of the articles showed that the major challenges for practitioners originate from overcoming a feature-driven mindset, not including a lot of details in the product roadmap, and ensuring that the content of the roadmap is not driven by management or expert opinion.
Providing a digital infrastructure, platform technologies foster interfirm collaboration between loosely coupled companies, enabling the formation of ecosystems and building the organizational structure for value co-creation. Despite the known potential, the development of platform ecosystems creates new sources of complexity and uncertainty due to the involvement of various independent actors. For a platform ecosystem to succeed, it is essential that the platform ecosystem participants are aligned, coordinated, and given a common direction. Traditionally, product roadmaps have served these purposes during product development. A systematic mapping study was conducted to better understand how product roadmapping could be used in the dynamic environment of platform ecosystems. One result of the study is that there are hardly any concrete approaches for product roadmapping in platform ecosystems so far. However, many challenges on the topic are described in the literature from different perspectives. Based on the results of the systematic mapping study, a research agenda for product roadmapping in platform ecosystems is derived and presented.
Context: Nowadays the market environment is characterized by high uncertainties due to high market dynamics, confronting companies with new challenges in creating and updating product roadmaps. Most companies are still using traditional approaches which typically fail in such environments. Therefore, companies are seeking opportunities for new product roadmapping approaches.
Objective: This paper presents good practices to support companies better understand what factors are required to conduct a successful product roadmapping in a dynamic and uncertain market environment.
Method: Based on a grey literature review, essential aspects for conducting product roadmapping in a dynamic and uncertain market environment were identified. Expert workshops were then held with two researchers and three practitioners to develop best practices and the proposed approach for an outcome-driven roadmap. These results were then given to another set of practitioners and their perceptions were gathered through interviews.
Results: The study results in the development of 9 good practices that provide practitioners with insights into what aspects are crucial for product roadmapping in a dynamic and uncertain market environment. Moreover, we propose an approach to product roadmapping that includes providing a flexible structure and focusing on delivering value to the customer and the business. To ensure the latter, this approach consists of the main items outcome hypothesis, validated outcomes, and discovered outputs.
There is a growing consensus in research and practice that value-creating networks and ecosystems are supplementing the traditional distinction between the internal firm and market perspectives. To achieve joint value in ecosystems, it is crucial to align the various interests of independently acting ecosystem actors and create a common vision. In this paper, we argue that the ecosystem-wide use of product roadmaps may help with this. To get a better understanding of how roadmapping is conducted in the dynamic ecosystem environment, we systematize the main characteristics of product roadmaps and perform a conceptual comparison with the known challenges of ecosystem management. Comparing the two concepts of ecosystems and product roadmaps, we highlight the fit between the characteristics and objectives of the roadmaps and the challenges of ecosystem management. Hence, we propose to experiment with the ecosystem-wide use of product roadmaps as well as the empirical study of the challenges emerging in the process and the associated redesign of the roadmaps.
Theoretical foundation, effectiveness, and design artefact for machine learning service repositories
(2022)
Machine learning (ML) has played an important role in research in recent years. For companies that want to use ML, finding the algorithms and models that fit for their business is tedious. A review of the available literature on this problem indicates only a few research papers. Given this gap, the aim of this paper is to design an effective and easy-to-use ML service repository. The corresponding research is based on a multi-vocal literature analysis combined with design science research, addressing three research questions: (1) How is current white and gray literature on ML services structured with respect to repositories? (2) Which features are relevant for an effective ML service repository? (3) How is a prototype for an effective ML service repository conceptualized? Findings are relevant for the explanation of user acceptance of ML repositories. This is essential for corporate practice in order to create and use ML repositories effectively.
Today, companies face increasing market dynamics, rapidly evolving technologies, and rapid changes in customer behavior. Traditional approaches to product development typically fail in such environments and require companies to transform their often feature-driven mindset into a product-led mindset. A promising first step on the way to a product-led company is a better understanding of how product planning can be adapted to the requirements of an increasingly dynamic and uncertain market environment in the sense of product roadmapping. The authors developed the DEEP product roadmap assessment tool to help companies evaluate their current product roadmap practices and identify appropriate actions to transition to a more product-led company. Objective: The goal of this paper is to gain insight into the applicability and usefulness of version 1.1 of the DEEP model. In addition, the benefits, and implications of using the DEEP model in corporate contexts will be explored. Method: We conducted a multiple case study in which participants were observed using the DEEP model. We then interviewed each participant to understand their perceptions of the DEEP model. In addition, we conducted interviews with each company's product management department to learn how the application of the DEEP model influenced their attitudes toward product roadmapping. Results: The study showed that by applying the DEEP model, participants better understood which artifacts and methods were critical to product roadmapping success in a dynamic and uncertain market environment. In addition, the application of the DEEP model helped convince management and other stakeholders of the need to change current product roadmapping practices. The application also proved to be a suitable starting point for the transformation in the participating companies.
The energy turnaround, digitalization and decreasing revenues forces enterprises in the energy domain to develop new business models. Following a Design Science Research approach, we showed in two action research projects that businesses models in the energy domain result in complex ecosystems with multiple actors. Additionally, we identified that municipal utilities have problems with the systematic development of business models. In order to solve the problem, we captured together with the partners of the enterprises the requirements in a second phase. Further we developed a method which consist of the following components: Method for the creative development of a new business model in form of a Business Model Canvas (BMC). A mapping between the e3Value ontology and the BMC for modelling a business ecosystem. The Business Model Configurator (BMConfig) prototype for modelling and simulating the e3Value-Ontology. The Business model can be quantified and analyzed for its viability. We demonstrate the feasibility of our approach in business model of a power community.
The rapid development and growth of knowledge has resulted in a rich stream of literature on various topics. Information systems (IS) research is becoming increasingly extensive, complex, and heterogeneous. Therefore, a proper understanding and timely analysis of the existing body of knowledge are important to identify emerging topics and research gaps. Despite the advances of information technology in the context of big data, machine learning, and text mining, the implementation of systematic literature reviews (SLRs) is in most cases still a purely manual task. This might lead to serious shortcomings of SLRs in terms of quality and time. The outlined approach in this paper supports the process of SLRs with machine learning techniques. For this purpose, we develop a framework with embedded steps of text mining, cluster analysis, and network analysis to analyze and structure a large amount of research literature. Although the framework is presented using IS research as an example, it is not limited to the IS field but can also be applied to other research areas.