The 10 most recently published documents
Gegenstand dieser Arbeit ist die Darstellung und Charakterisierung einheitlicher, mesoporöser Silica-Partikel (MPSM) im Mikrometerbereich mit maßgeschneiderten Partikel- und Porendesign für die Hochleistungsflüssigkeitschromatographie. Die Synthese umfasst die Einlagerung von Silica-Nanopartikeln (SNP) in poröse organische Template, welche anschließend bei 600°C zersetzt werden. Die Impfsuspensionspolymerisation von Polystyrol-Partikeln, unter Verwendung von Glycidylmethacrylat, Ethylenglycoldimethacrylat und Porogenen, ermöglicht die Herstellung hochgradig einheitlicher, poröser p(GMA-co-EDMA)-Template. Der Einfluss wesentlicher Faktoren, einschließlich des Monomer-Porogen-Verhältnisses, des Monomerverhältnisses und der Porogenzusammensetzung, werden systematisch untersucht sowie ihre Auswirkungen auf die Porengröße, das Porenvolumen und die spezifische Oberfläche erläutert. Die Anbindung aminofunktionalisierter Substanzen erfolgt durch die Ringöffnung der Epoxidgruppe. Im anschließenden basischen Sol-Gel-Prozess werden die Silica-Nanopartikel aufgrund der Ladungsunterschiede in die funktionalisierten p(GMA-co-EDMA)-Template eingebaut. Die Partikelgröße der SNP beeinflusst wesentlich die Poreneigenschaften der MPSM und hängt von drei Faktoren ab: (i) der Wachstumsgeschwindigkeit in der kontinuierlichen Phase, die durch die Einstellungen des Sol-Gel-Prozesses gesteuert wird, (ii) der Diffusionsrate, die durch elektrostatische Anziehung reguliert wird und vom Grad der Funktionalisierung abhängt und (iii) der Porosität des Polymer-Templats. Die gezielte Anpassung der Poreneigenschaften durch die Prozesseinstellungen erlaubt die präzise Herstellung von MPSM, die auf spezifische Trennherausforderungen zugeschnitten werden und somit die Qualität der HPLC verbessern. Die vorgestellte Synthesestrategie ermöglicht, aufgrund des stufenweisen molekularen Aufbaus, eine bessere Adaption der stationären Phase an spezifische Trennherausforderungen.
The targeted design of monodisperse, mesoporous silica microspheres (MPSMs) as HPLC separation phases is still a challenge. The MPSMs can be generated via a multi-step template-assisted method. However, this method and the factors affecting the individual process steps and resulting material properties are scarcely understood, and specific control of the complex multi-step process has been hardly discussed. In this work, the key synthesis steps were systematically investigated by means of statistical Design of Experiment (DoE). In particular, three steps were considered in detail: 1) the synthesis of porous poly(glycidyl methacrylate-co-ethylene glycol dimethacrylate) (p(GMA-co-EDMA)) particles, which as template particles, determine the structure for the final MPSMs. In this context, functional models were generated, which allow the control of the template properties pore volume, pore size and specific surface area. 2) In the presence of amino-functionalized template particles, the sol-gel process was carried out under Stöber process conditions. The water to tetraethyl orthosilicate (TEOS) ratio, as well as the concentration of ammonia as basic catalyst were varied according to a face-centered central composite design (FCD). The incorporation of silica nanoparticles (SNPs) into the pore network of the porous polymers was investigated by scanning electron microscopy (SEM), evaluation of the pore properties assessed by nitrogen sorption measurements and determination of the inorganic content by thermogravimetric analysis (TGA). Here, the material properties, such as the amount of attached silica, can be specifically controlled in the resulting organic/silica hybrid material (hybrid beads, HBs). Furthermore, depending on the sol-gel conditions three, potentially four, reaction regimes were identified, leading to different HBs. These range from porous polymer particles coated with a thin protective silica layer, to interpenetrating networks of polymer and silica, to potential particles consisting of a porous polymer core coated with a silica shell. Also, the effects of the use of different precursors and solvents on silica incorporation were investigated. 3) To obtain MPSMs from the HBs, the organic polymer template was removed by calcination. The effects of sol-gel process conditions on the resulting MPSMs were evaluated and relationships between process conditions and material properties were shown in predictive models. Fully porous, spherical, monodisperse silica particles with sizes ranging from 0.5 µm to 7.8 µm and pore sizes from 3.5 nm to 72.4 nm can be prepared specifically. Subsequent to organo-functionalization, prepared MPSMs were applied as reversed-phase HPLC column materials. Here, the columns were successfully applied for the separation of proteins and amino acids. The separation performance of the materials depends largely on the property profile of the MPSMs, which is predetermined during the preparation of the HBs.
In the context of Industry 4.0, intralogistics faces an increasingly complex and dynamic environment driven by a high level of product customisation and complex manufacturing processes. One approach to deal with these changing conditions is the decentralised and intelligent connectivity of intralogistics systems. However, wireless connectivity presents a major challenge in the industry due to strict requirements such as safety and real-time data transmission. In this context, the fifth generation of mobile communications (5G) is a promising technology to meet the requirements of safety-critical applications. Particularly, since 5G offers the possibility of establishing private 5G networks, also referred to as standalone non-public networks. Through their isolation from public networks, private 5G networks provide exclusive coverage for private organisations offering them high intrinsic network control and data security. However, 5G is still under development and is being gradually introduced in a continuous release process. This process lacks transparency regarding the performance of 5G in individual releases, complicating the successful adoption of 5G as an industrial communication. Additionally, the evaluation of 5G against the specified target performance is insufficient due to the impact of the environment and external interfering factors on 5G in the industrial environment. Therefore, this paper aims to develop a technical decision-support framework that takes a holistic approach to evaluate the practicality of 5G for intralogistics use cases by considering two fundamental stages. The first of these analyses technical parameters and characteristics of the use case to evaluate the theoretical feasibility of 5G. The second stage investigates the application's environment, which substantially impacts the practicality of 5G, for instance, the influence of surrounding materials. Finally, a case study validates the proposed framework by means of an autonomous mobile robot. As a result, the validation proves the proposed framework's applicability and shows the practicality of the autonomous mobile robot, when integrating it into a private 5G network testbed.
In the era of digital transformation, the notion of software quality transcends its traditional boundaries, necessitating an expansion to encompass the realms of value creation for customers and the business. Merely optimizing technical aspects of software quality can result in diminishing returns. Product discovery techniques can be seen as a powerful mechanism for crafting products that align with an expanded concept of quality - one that incorporates value creation. Previous research has shown that companies struggle to determine appropriate product discovery techniques for generating, validating, and prioritizing ideas for new products or features to ensure they meet the needs and desires of the customers and the business. For this reason, we conducted a grey literature review to identify various techniques for product discovery. First, the article provides an overview of different techniques and assesses how frequently they are mentioned in the literature review. Second, we mapped these techniques to an existing product discovery process from previous research to provide concrete guidelines for establishing product discovery in their organizations. The analysis shows, among other things, the increasing importance of techniques to structure the problem exploration process and the product strategy process. The results are interpreted regarding the importance of the techniques to practical applications and recognizable trends.
Cyber-Physical Production Systems increasingly use semantic information to meet the grown flexibility requirements. Ontologies are often used to represent and use this semantic information. Existing systems focus on mapping knowledge and less on the exchange with other relevant IT systems (e.g., ERP systems) in which crucial semantic information, often implicit, is contained. This article presents an approach that enables the exchange of semantic information via adapters. The approach is demonstrated by a use case utilizing an MES system and an ERP system.
Transforming our food system is important to achieving global climate neutrality and food security. Germany has set a national target of reaching a 30% share in organic farming to support the goal. When looking at the transformation process from conventional to organic farming, it becomes apparent that measures need to be taken to reach this anticipated goal. A particular emphasis of this work is placed on finding a digital solution and process improvements to ensure longevity and efficiency. Interviews with actors along the farm-to-fork value chain were conducted to identify central barriers and drivers of organic transformation. The results of the interviews show firstly, that three subsystems need to be distinguished when talking about the farm-to-fork value chain: (1) farmers, (2) intermediaries, and (3) the canteen system. Although all three subsystems can be combined to form a coherent value chain, they rarely act and communicate beyond the boundaries of their subsystem. Secondly, we were able to allocate primary barriers and drivers to each of the subsystems, highlighting the need to include all three in the transformation process and aim for a comprehensive digital solution. This work explores the potential of a network-based platform to improve the current practice of rigid and strictly hierarchical value chains. We focus on deriving user requirements from the interviews to describe the necessary functionality of the platform to address the identified barriers and exploit existing drivers.
Applications often need to be deployed in different variants due to different customer requirements. However, since modern applications often need to be deployed using multiple deployment technologies in combination, such as Ansible and Terraform, the deployment variability must be considered in a holistic way. To tackle this, we previously developed Variability4TOSCA and the prototype OpenTOSCA Vintner, which is a TOSCA preprocessing and management layer that implements Variability4TOSCA. In this demonstration, we present a detailed case study that shows how to model a deployment using Variability4TOSCA, how to resolve the variability using Vintner, and how the result can be deployed.
Gamification has been increasingly applied to software engineering education in the past. The approaches vary from applying game elements on a conceptual phase in the course to using specific tools to engage the students more and support their learning goals. However, existing tools usually have game elements, such as quizzes or challenges, but do not provide a more computer game-like experience. Therefore, we try to raise the level of gamified learning experience to another level by proposing Gamify-IT. Gamify-IT is a Unity- and web-based game platform intended to help students learn software engineering. It follows an immersive role-play game characteristic where the students explore a world, find and solve minigames and clear dungeons with SE tasks. Lecturers can configure the worlds, e.g., to add content hints. Furthermore, they can add and configure minigames and dungeons to include exercises in a fully gamified way. Thereby, they customize their course in Gamify-IT to adapt the world very precisely to other materials such as lectures or exercises. Results of an evaluation of our initial prototype show that (i) students like to engage with the platform, (ii) students are motivated to learn when using Gamify-IT, and (iii) the minigames support students in understanding the learning objectives.
Intelligent Tutoring Systems (ITSs) are increasingly used in modern education to automatically give students individual feedback on their performance. The advantage for students is fast individual feedback on their answers to asked questions, while lecturers benefit from considerable time savings and easy delivery of educational material. Of course, it is important that the provided feedback is as effective as direct feedback from the lecturer. However, in digital teaching, lecturers cannot assess the student’s knowledge precisely but can only provide information on which questions were answered correctly and incorrectly. Therefore, this paper presents a concept for integrating ITS elements into the gamified e-learning platform IT-REX so that the feedback quality can be improved to support students in the best possible way.
The COVID-19 pandemic necessitated significant changes in foreign language education, forcing teachers to reconstruct their identities and redefine their roles as language educators. To better understand these adaptations and perspectives, it is crucial to study how the pandemic has influenced teaching practices. This mixed-methods study focused on the less-explored aspects of foreign language teaching during the pandemic, specifically examining how language teachers adapted and perceived their practices, including rapport building and learner autonomy, during emergency remote teaching (ERT) in higher education institutions. It also explored teachers’ intentions for their teaching in the post-pandemic era. An online survey was conducted, involving 118 language educators primarily from Germany, with a smaller representation from New Zealand, the United States, and the United Kingdom. The analysis of participants’ responses revealed issues and opportunities regarding lesson formats, tool usage, rapport, and learner autonomy. Our findings offer insights into the desired changes participants envisioned for the post-pandemic era. The results highlight the opportunities ERT had created in terms of teacher development, and we offer suggestions to enhance professional development programmes based on these findings.