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Business process management and IT supported processes are an actual topic. The procedure of finding a business process system that implements your processes the best way is not easy and takes a lot of time. In this article you will find a recommendation for an open source system. Four selected open source workflow management systems are tested and analyzed. Mean criteria for the evaluation are listed in a criteria catalogue and rated by experts by their importance. Finally, the systems are evaluated by the criteria and the best evaluated system can be recommended.
Willingness-to-pay for alternative fuel vehicle characteristics : a stated choice study for Germany
(2016)
In the light of European energy efficiency and clean air regulations, as well as an ambitious electric mobility goal of the German government, we examine consumer preferences for alternative fuel vehicles (AFVs) based on a Germany-wide discrete choice experiment among 711 potential car buyers. We estimate consumers’ willingness to-pay and compensating variation (CV) for improvements in vehicle attributes, also taking taste differences in the population into account by applying a latent class model with 6 distinct consumer segments. Our results indicate that about 1/3 of the consumers are oriented towards at least one AFV option, with almost half of them being AFV-affine, showing a high probability of choosing AFVs despite their current shortcomings. Our results suggest that German car buyers’ willingness-to-pay for improvements of the various vehicle attributes varies considerably across consumer groups and that the vehicle features have to meet some minimum requirements for considering AFVs. The CV values show that decision-makers in the administration and industry should focus on the most promising consumer group of ‘AFV aficionados’ and their needs. It also shows that some vehicle attribute improvements could increase the demand for AFVs cost-effectively, and that consumers would accept surcharges for some vehicle attributes at a level which could enable their private provision and economic operation (e.g. fast-charging infrastructure). Improvement of other attributes will need governmental subsidies to compensate for insufficient consumer valuation (e.g. battery capacity).
Software development consists to a large extend of humanbased processes with continuously increasing demands regarding interdisciplinary team work. Understanding the dynamics of software teams can be seen as highly important to successful project execution. Hence, for future project managers, knowledge about non-technical processes in teams is significant. In this paper, we present a course unit that provides an environment in which students can learn and experience the impact of group dynamics on project performance and quality. The course unit uses the Tuckman model as theoretical framework, and borrows from controlled experiments to organize and implement its practical parts in which students then experience the effects of, e.g., time pressure, resource bottlenecks, staff turnover, loss of key personnel, and other stress factors. We provide a detailed design of the course unit to allow for implementation in further software project management courses. Furthermore, we provide experiences obtained from two instances of this unit conducted in Munich and Karlskrona with 36 graduate students. We observed students building awareness of stress factors and developing counter measures to reduce impact of those factors. Moreover, students experienced what problems occur when teams work under stress and how to form a performing team despite exceptional situations.
The question of why individuals adopt information technology has been present in the information systems research since the past quarter century. One of the most used models for predicting the technology usage was introduced by Fred David: The Technology Acceptance Model (TAM). It describes the influence of perceived usefulness and perceived ease of use on attitude, behavioral intention and system usage. The first two mentioned factors in turn are influenced by external variables. Although a plethora of papers exists about the TAM , an extensive analysis of the role of the external variables in the model is still missing. This paper aims to give an overview ove the most important variables. In an extensive literature review, we identified 763 relevant papers, found 552 unique single extenal variables, characterized the most important of them, and described the frequency of their appearance. Additionally, we grouped these variables into four categories (organizational characteristis, system characteristics, user personal characteristics, and other variables). Afterwards we discuss the results and show implications for theory and practice.
Wasted paradise – imagining the Maldives without the garbage island of Thilafushi : Version 1.2
(2016)
To address the high level of waste production in the Maldives, the local government decided to transform the coral island of Thilafushi into an immense waste dumb in 1992. Meanwhile, each day, 330 tons of waste is ferried to Thilafushi. The policy had the positive consequence of relieving the garbage burden in Malé, the main island, and surrounding tourist atolls. However, it can also lead to serious environmental and economic damage in the long range. First, the garbage is in visual range of one of the most prominent tourist destinations. Second, if the wind blows a certain way, unfiltered fumes from burning waste travels to tourist atolls. Third, water quality can erode as hazardous waste from batteries and other toxic waste is floating in the ocean. Over time, these effects can accumulate to significantly hamper the number of tourists that travel to the Maldives – one of the state’s main sources of financial income. In our paper, we lay out the situation in more detail and translate it into a simulation model. We test different policies to propose the Maldives government how to better solve the waste problem.
Organisationen sind immer mehr gefragt, auch digitale Arbeitsumgebungen bewusst zu formen. Neue Technologien und digitale Arbeitspraktiken verlagern den Ort, an dem eine gemeinsame Identität gebildet wird, zunehmend in virtuelle Räume. Bislang fokussieren sich Führungskräfte und Change Manager jedoch zu sehr auf Dinge, die sie anfassen und plastisch gestalten können. Die Autoren erörtern daher, wie Unternehmen auch in virtuellen Arbeitswelten die organisationale Identität gestalten und aufrechterhalten können, um auf diese Weise das Change Management zu unterstützen.
Bei weitgehend gleicher Ausstattung und neuen Anforderungen an die Hochschulrechenzentren rücken Kooperationen zunehmend in den Mittelpunkt. Für diese,
auch hochschulartenübergreifende, Kooperationen genügt der klassische informelle Rahmen vielfach nicht mehr. Für eine erfolgreiche Zusammenarbeit sind einige Voraussetzungen zu erfüllen. Rechenzentren treten in neuer Rolle als Provider von Dienstleistungen für Nutzer auch außerhalb ihrer eigenen Hochschule auf. Ebenso
könnten sie sich zukünftig verstärkt in der Nutzerperspektive wiederfinden. IT-Service-Einrichtungen müssen sich ihrer neuen Rolle als Diensteanbieter und Nutzer von Diensten Dritter bewusst werden und diese in ihre Überlegungen für die Ausgestaltung neuer Dienste einfließen lassen.
Based on well-established robotic concepts of autonomous localization and navigation we present a system prototype to assist camera-based indoor navigation for human utilization implemented in the Robot Operating System (ROS). Our prototype takes advantage of state-of-the-art computer vision and robotic methods. Our system is designed for assistive indoor guidance. We employ a vibro tactile belt to serve as a guiding device to render derived motion suggestions to the user via vibration patterns. We evaluated the effectiveness of a variety of vibro-tactile feedback patterns for guidance of blindfolded users. Our prototype demonstrates that a vision-based system can support human navigation, and may also assist the visually impaired in a human-centered way.
Today the optimization of metal forming processes is done using advanced simulation tools in a virtual process, e.g. FEM-studies. The modification of the free parameters represents the different variants to be analysed. So experienced engineers may derive useful proposals in an acceptable time if good initial proposals are available. As soon as the number of free parameters growths or the total process takes long times and uses different succeeding forming steps it might be quite difficult to find promising initial ideas. In metal forming another problem has to be considered. The optimization using a series of local improvements, often called a gradient approach may find a local optimum, but this could be far away from a satisfactory solution. Therefore non-deterministic approaches, e.g. Bionic Optimization have to be used. These approaches like Evolutionary Optimization or Particle Swarm Optimization are capable to cover a large range of high dimensional optimization spaces and discover many local optima. So the chance to include the global optimum increases when using such non-deterministic methods. Unfortunately these bionic methods require large numbers of studies of different variants of the process to be optimized. The number of studies tends to increase exponentially with the number of free parameters of the forming process. As the time for one single study might be not too small as well, the total time demand will be inacceptable, taking weeks to months even if high performance computing will be used. Therefore the optimization process needs to be accelerated. Among the many ideas to reduce the time and computer power requirement Meta- and Hybrid Optimization seem to produce the most efficient results. Hybrid Optimization often consists of global searches of promising regions within the parameter space. As soon as the studies indicate that there could be a local optimum, a deterministic study tries to identify this local region. If it shows better performance than other optima found until now, it is preserved for a more detailed analysis. If it performs worse than other optima the region is excluded from further search. Meta-Optimization is often understood as the derivation of Response Surfaces of the functions of free parameters. Once there are enough studies performed, the optimization is done using the Response Surfaces as representatives e.g. for the goal and the restrictions of the optimization problem. Having found regions where interesting solutions are to be expected, the studies available up to now are used to define the Response Surfaces. In many cases low degree polynomials are used, defining their coefficients by least square methods. Both proposals Hybrid Optimization and Meta-Optimization, sometimes used in combination often help to reduce the total optimization processes by large numbers of variants to be studied. In consequence they are highly recommended when dealing with time consuming optimization studies.
"Wer nicht vielfältig denkt, denkt einfältig". Mit diesem Spruch machen Studierende der Hochschule Reutlingen in einem Videoclip auf das Thema Diversity aufmerksam. Doch was verstehen wir eigentlich darunter? Seit September letzten Jahres ist Professorin Dr. Gabriela Tullius Vizepräsidentin der Hochschule Reutlingen und widmet sich unter anderem diesem Bereich. GEA-Campus hat nachgefragt, worum es bei Diversity geht und warum dieser Bereich die Hochschule beschäftigt.
Marketing-Events emotionalisieren das Publikum auf besondere Art und Weise. Einstellungsänderungen bzw. Imageverbesserungen stellen deshalb die zentralen Zielsetzungen des Event-Marketing dar. Aufbauend auf den wesentlichen Grundlagen des Event-Marketing fokussiert dieses Kapitel auf das Controlling im Event-Marketing. Eingegangen wird auf die Erfolgskontrolle und die Wirkungsforschung im Event-Marketing. Es werden die Bedingungen für das Zustandekommen eines Imagetransfers von einem Event auf eine Marke bzw. ein Unternehmen erläutert und Verfahren zur Imagemessung vorgestellt.
Tumorzellen on the move : mikrosystem-basierter Assay zur Untersuchung der Tumorzellen-Migration
(2016)
Die Invasion von Tumorzellen in umliegendes Gewebe und die Bildung von Metastasen transformieren einen lokal wachsenden Tumor in eine systemische und lebensbedrohliche Krankheit mit schlechter Prognose. Dabei spielt die aktive Migration der Tumorzellen eine entscheidende Rolle. Tumorzellen gelangen durch die aktive Zellbewegung in das Lymph- oder Blutsystem und breiten sich im Körper aus. Bei der Invasion in ein neues Organ migrieren die Zellen ebenfalls wieder in komplexer Weise durch das Gewebe und können schließlich dort Metastasen bilden. Auf Grund der enormen medizinischen Relevanz der Tumorzell-Invasion, wird die Bewegung von Tumorzellen seit Jahrzehnten unter Laborbedingungen umfassend untersucht und ist ein wichtiger Marker für die Aggressivität der Tumorzellen. Zur Bewegungsanalyse gibt es mehrere experimentelle und auch kommerziell erhältliche in-vitro Untersuchungsmethoden. Ziel des interdisziplinären Projektes „MigChip“ ist die Entwicklung, Herstellung und experimentelle Validierung eines Mikrofludik-Chips zur verbesserten, detailgenauen in-vitro Untersuchung der Tumorzellen-Migration.
Context: Companies need capabilities to evaluate the customer value of software intensive products and services. One way of systematically acquiring data on customer value is running continuous experiments as part of the overall development process. Objective: This paper investigates the first steps of transitioning towards continuous experimentation in a large company, including the challenges faced. Method: We conduct a single-case study using participant observation, interviews, and qualitative analysis of the collected data. Results: Results show that continuous experimentation was well received by the practitioners and practising experimentation helped them to enhance understanding of their product value and user needs. Although the complexities of a large multi-stakeholder business to-business (B2B) environment presented several challenges such as inaccessible users, it was possible to address impediments and integrate an experiment in an ongoing development project. Conclusion: Developing the capability for continuous experimentation in large organisations is a learning process which can be supported by a systematic introduction approach with the guidance of experts. We gained experience by introducing the approach on a small scale in a large organisation, and one of the major steps for future work is to understand how this can be scaled up to the whole development organisation.
IT environments that consist of a very large number of rather small structures like microservices, Internet of Things (IoT) components, or mobility systems are emerging to support flexible and agile products and services in the age of digital transformation. Biological metaphors of living and adaptable ecosystems with service-oriented enterprise architectures provide the foundation for self-optimizing, resilient run-time environments and distributed information systems. We are extending Enterprise Architecture (EA) methodologies and models that cover a high degree of heterogeneity and distribution to support the digital transformation and related information systems with micro-granular architectures. Our aim is to support flexibility and agile transformation for both IT and business capabilities within adaptable digital enterprise architectures. The present research paper investigates mechanisms for integrating Microservice Architectures (MSA) by extending original enterprise architecture reference models with elements for more flexible architectural metamodels and EA-mini-descriptions.
Analysis is an important part of the enterprise architecture management process. Prior to decisions regarding transformation of the enterprise architecture, the current situation and the outcomes of alternative action plans have to be analysed. Many analysis approaches have been proposed by researchers and current enterprise architecture management tools implement analysis functionalities. However, few work has been done structuring and classifying enterprise architecture analysis approaches. This paper collects and extends existing classification schemes, presenting a framework for enterprise architecture analysis classification. For evaluation, a collection of enterprise architecture analysis approaches has been classified based on this framework. As a result, the description of these approaches has been assessed, a common set of important categories for enterprise architecture analysis classification has been derived and suggestions for further development are drawn.
The reduced research and development (R&D) efficiency, strong competition from generics, increased cost pressure from payers, and an increased biological complexity of new target indications have resulted in a rethinking and a change from a traditional and more closed R&D model in the pharmaceutical industry toward the new paradigm of open innovation. In the past years, pharmaceutical companies have broadened their external networks toward research collaborations with academic institutes, technology providers, or codevelopment partners. To fulfill the demand to reduce timelines and costs, research-based pharmaceutical companies started to outsource R&D activities. In addition, internal R&D processes were adjusted to the more open R&D model and new processes such as alliance management were established. The corporate frontier of pharmaceutical companies became permeable and more open. As a result, the focus of pharmaceutical R&D expanded from a purely internal toward a mixed internal and external model. Today, the U.S. pharmaceutical company Eli Lilly may have established the most open model toward external innovation, as it has integrated its innovation processes with its business model. Other companies are following this more open R&D model with newer concepts such as new frontier sciences, drug discovery alliances, private public partnerships, innovation incubators, virtual R&D, crowdsourcing, open source innovation, and innovation camps.
During the first years of their employment, the graduates are a liability to industry. The employer goes an extra mile to bridge the gap between university-exiting and profitable employment of engineering graduates. Unfortunately some cannot take this risk. Given this scenario, this paper presents a learning factory approach as a platform for the application of knowledge so as to develop the required engineering competences in South African engineering graduates before they enter the labour market. It spells out the components of a Stellenbosch University Learning Factory geared towards production of engineering graduates with the required industrial skills. It elaborates on the didactics embedded in the learning factory environment, tailor-made to produce engineers who can productively contribute to the growth of the industry upon exiting the university.
Clinical development is historically the phase in which a potential new medicine is being tested in phase 2 and phase 3 patient trials to demonstrate the new molecules' efficacy and safety to support the regulatory approval of drugs by health authorities. This relatively focused approach has been considerably expanded by a number of forces from within the pharmaceutical industry and equally important by changes in the healthcare systems. The need to identify the optimal patient population, showstoppers leading to discontinuation of clinical programs, the silent but constant removal of surrogate endpoints for registration, and the increased demand for real-life data which are used to demonstrate the patients' benefit and which have an ever-increasing role for pricing and reimbursement negotiations are today an integral part of this phase.
This chapter will review both the nuts and bolts of clinical development but also recent developments in this area which shape the environment and how the different players have reacted and what options might need to be explored in the future.