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Despite the unstoppable global drive towards electric mobility, the electrification of sub-Saharan Africa’s ubiquitous informal multi-passenger minibus taxis raises substantial concerns. This is due to a constrained electricity system, both in terms of generation capacity and distribution networks. Without careful planning and mitigation, the additional load of charging hundreds of thousands of electric minibus taxis during peak demand times could prove catastrophic. This paper assesses the impact of charging 202 of these taxis in Johannesburg, South Africa. The potential of using external stationary battery storage and solar PV generation is assessed to reduce both peak grid demand and total energy drawn from the grid. With the addition of stationary battery storage of an equivalent of 60 kWh/taxi and a solar plant of an equivalent of 9.45 kWpk/taxi, the grid load impact is reduced by 66%, from 12 kW/taxi to 4 kW/taxi, and the daily grid energy by 58% from 87 kWh/taxi to 47 kWh/taxi. The country’s dependence on coal to generate electricity, including the solar PV supply, also reduces greenhouse gas emissions by 58%.
In this paper, the essential sponsorship basics are presented and the communication instrument of sports sponsorship is illustrated. Building on this, both the perspectives of sponsors and sponsees are examined in detail. In addition, the special features of sports event sponsorships are highlighted. Finally, current developments in sports sponsorship in the context of the FIFA Soccer World Cup 2022 in Qatar and the UEFA European Soccer Championship 2024 in Germany are compared and discussed.
Wave-like differential equations occur in many engineering applications. Here the engineering setup is embedded into the framework of functional analysis of modern mathematical physics. After an overview, the –Hilbert space approach to free Euler–Bernoulli bending vibrations of a beam in one spatial dimension is investigated. We analyze in detail the corresponding positive, selfadjoint differential operators of 4-th order associated to the boundary conditions in statics. A comparison with free string wave swinging is outlined.
Tech hubs (THs) and cognate structures are nowadays ubiquitous in the innovation ecosystem of Sub-Saharan African (SSA) countries. However, the concept of THs is fuzzy due to the lack of a clear and universally accepted definition. This ambiguity is further compounded by the diverse range of organizations that self-identify as hubs, or are categorized as such by others. As a result, research on THs in SSA remained limited. Against the backdrop of established research on the interconnectedness of technology, innovation and entrepreneurship in different organizational forms, this paper is meant to provide fresh insights into the study of THs in SSA. To advance future research, first, it reveals what is special about THs in SSA and how they are related to existing concepts. I particularly argue that they contour a fourth-wave model of incubation. Second, four main categories are unfolded to delineate THs in SSA which is the cornerstone for future research.
Salivary gland tumors (SGTs) are a relevant, highly diverse subgroup of head and neck tumors whose entity determination can be difficult. Confocal Raman imaging in combination with multivariate data analysis may possibly support their correct classification. For the analysis of the translational potential of Raman imaging in SGT determination, a multi-stage evaluation process is necessary. By measuring a sample set of Warthin tumor, pleomorphic adenoma and non-tumor salivary gland tissue, Raman data were obtained and a thorough Raman band analysis was performed. This evaluation revealed highly overlapping Raman patterns with only minor spectral differences. Consequently, a principal component analysis (PCA) was calculated and further combined with a discriminant analysis (DA) to enable the best possible distinction. The PCA-DA model was characterized by accuracy, sensitivity, selectivity and precision values above 90% and validated by predicting model-unknown Raman spectra, of which 93% were classified correctly. Thus, we state our PCA-DA to be suitable for parotid tumor and non-salivary salivary gland tissue discrimination and prediction. For evaluation of the translational potential, further validation steps are necessary.
Automatic content creation system for augmented reality maintenance applications for legacy machines
(2024)
Augmented reality (AR) applications have great potential to assist maintenance workers in their operations. However, creating AR solutions is time-consuming and laborious, which limits its widespread adoption in the industry. It therefore often happens that even with the latest generation machines, instead of an AR solution, the user only receives an electronic manual for the equipment operation and maintenance. This is commonplace with legacy machines. For this reason, solutions are required that simplify the creation of such AR solutions. This paper presents an approach using an electronic manual as a basis to create fast and cost-effective AR solutions for maintenance. As part of the approach, an application was developed to automatically identify and subdivide the chapters of electronic manuals via the bookmarks in the table of contents. The contents are then automatically uploaded to a central server and indexed with a suitable marker to make the data retrievable. The prepared content can then be accessed for creating context-related AR instructions via the marker. The application is characterized by the fact that no developers or experts are required to prepare the information. In addition to complying with common design criteria, the clear presentation of the contents and the intuitive use of the system offer added value for the performance of maintenance tasks. Together, these two elements form a novel way to retrofit legacy machines with AR maintenance instructions. The practical validation of the system took place in a factory environment. For this purpose, the content was created for a filter change on a CNC milling machine. The results show that inexperienced users can extract appropriate content with the software application. Furthermore, it is shown that maintenance workers, can access the content with an AR application developed for the Microsoft HoloLens 2 and complete simple tasks provided in the manufacturer's electronic manual.
Based on social information processing theory, this research examines whether and how an employee’s proactive personality influences intrinsic and extrinsic career growth. It also examines the mediating effects of two types of proactive behaviors (voice behavior and taking charge) and the moderating effect of a leader’s proactive personality. A sample of 307 employee-leader dyads participated in this survey. Structural equation modeling was used to test the hypotheses, and the bootstrap procedure was used to test the indirect effects. Results show that an employee’s proactive personality has significant positive effects on both intrinsic and extrinsic career growth. The mediating effect of taking charge was confirmed, while the mediating effect of voice behavior was not. Leader proactive personality weakens the relationship between employee proactive personality and the two types of proactive behaviors. Employee proactive personality is more positively related to intrinsic and extrinsic career growth via proactive behaviors when a leader’s proactive personality is low. This study extends the literature on proactive personality, proactive behavior, and career development by examining the underlying determination, mediation, and moderation mechanisms.
For optimization of production processes and product quality, often knowledge of the factors influencing the process outcome is compulsory. Thus, process analytical technology (PAT) that allows deeper insight into the process and results in a mathematical description of the process behavior as a simple function based on the most important process factors can help to achieve higher production efficiency and quality. The present study aims at characterizing a well-known industrial process, the transesterification reaction of rapeseed oil with methanol to produce fatty acid methyl esters (FAME) for usage as biodiesel in a continuous micro reactor set-up. To this end, a design of experiment approach is applied, where the effects of two process factors, the molar ratio and the total flow rate of the reactants, are investigated. The optimized process target response is the FAME mass fraction in the purified nonpolar phase of the product as a measure of reaction yield. The quantification is performed using attenuated total reflection infrared spectroscopy in combination with partial least squares regression. The data retrieved during the conduction of the DoE experimental plan were used for statistical analysis. A non-linear model indicating a synergistic interaction between the studied factors describes the reactor behavior with a high coefficient of determination (R²) of 0.9608. Thus, we applied a PAT approach to generate further insight into this established industrial process.
How mechanical and physicochemical material characteristics influence adipose-derived stem cell fate
(2023)
Adipose-derived stem cells (ASCs) are a subpopulation of mesenchymal stem cells. Compared to bone marrow-derived stem cells, they can be harvested with minimal invasiveness. ASCs can be easily expanded and were shown to be able to differentiate into several clinically relevant cell types. Therefore, this cell type represents a promising component in various tissue engineering and medical approaches (e.g., cell therapy). In vivo cells are surrounded by the extracellular matrix (ECM) that provides a wide range of tissue-specific physical and chemical cues, such as stiffness, topography, and chemical composition. Cells can sense the characteristics of their ECM and respond to them in a specific cellular behavior (e.g., proliferation or differentiation). Thus, in vitro biomaterial properties represent an important tool to control ASCs behavior. In this review, we give an overview of the current research in the mechanosensing of ASCs and current studies investigating the impact of material stiffens, topography, and chemical modification on ASC behavior. Additionally, we outline the use of natural ECM as a biomaterial and its interaction with ASCs regarding cellular behavior.
At the beginning of 2022, Frontiers in Bioengineering and Biotechnology - Biomaterials Section has published a Research Topic on “Functional Surfaces and Biomaterials.” The aim of this Research Topic is to summarize the current state of research and development in the field of functional surfaces and biomaterials with a particular focus on biotechnological and medical applications.
The guest editorial team would like to thank all colleagues from around the world who submitted their reviews and research articles for the Research Topic. By the end of August 2022, we have successfully collected 20 articles by 138 participating authors following the peer review process. We also tried to select manuscripts from different research areas to cover the most relevant Research Topic of interest, from drug delivery systems to bone tissue engineering to biosensors and general aspects in biomedicine. By the end of December, the 20 articles had been viewed for more than 21000 times with downloads more than 4,000 times, and 11 articles have reached more than 1,000 views.