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The introduction of smart contracts has expanded the applicability of blockchains to many domains beyond finance and cryptocurrencies. Moreover, different blockchain technologies have evolved that target special requirements. As a result, in practice, often a combination of different blockchain systems is required to achieve an overall goal. However, due to the heterogeneity of blockchain protocols, the execution of distributed business transactions that span several blockchains leads to multiple interoperability and integration challenges. Therefore, in this article, we examine the domain of Cross-Chain Smart Contract Invocations (CCSCIs), which are distributed transactions that involve the invocation of smart contracts hosted on two or more blockchain systems. We conduct a systematic multi-vocal literature review to get an overview of the available CCSCI approaches. We select 20 formal literature studies and 13 high-quality gray literature studies, extract data from them, and analyze it to derive the CCSCI Classification Framework. With the help of the framework, we group the approaches into two categories and eight subcategories. The approaches differ in multiple characteristics, e.g., the mechanisms they follow, and the capabilities and transaction processing semantics they offer. Our analysis indicates that all approaches suffer from obstacles that complicate real-world adoption, such as the low support for handling heterogeneity and the need for trusted third parties.
Software scripts for sensor data extraction in Rasberry Pi: user-space and kernel-space comparison
(2024)
This paper compares two popular scripting implementations for hardware prototyping: Python scripts execut from User-Space and C-based Linux-Driver processes executed from Kernel-Space, which can provide information to researchers when considering one or another in their implementations. Conclusions exhibit that deploying software scripts in the kernel space makes it possible to grant a certain quality of sensor information using a Raspberry Pi without the need for advanced real-time operational systems.
Human pose estimation (HPE) is integral to scene understanding in numerous safety-critical domains involving human-machine interaction, such as autonomous driving or semi-automated work environments. Avoiding costly mistakes is synonymous with anticipating failure in model predictions, which necessitates meta-judgments on the accuracy of the applied models. Here, we propose a straightforward human pose regression framework to examine the behavior of two established methods for simultaneous aleatoric and epistemic uncertainty estimation: maximum a-posteriori (MAP) estimation with Monte-Carlo variational inference and deep evidential regression (DER). First, we evaluate both approaches on the quality of their predicted variances and whether these truly capture the expected model error. The initial assessment indicates that both methods exhibit the overconfidence issue common in deep probabilistic models. This observation motivates our implementation of an additional recalibration step to extract reliable confidence intervals. We then take a closer look at deep evidential regression, which, to our knowledge, is applied comprehensively for the first time to the HPE problem. Experimental results indicate that DER behaves as expected in challenging and adverse conditions commonly occurring in HPE and that the predicted uncertainties match their purported aleatoric and epistemic sources. Notably, DER achieves smooth uncertainty estimates without the need for a costly sampling step, making it an attractive candidate for uncertainty estimation on resource-limited platforms.
This article provides a stochastic agent-based model to exhibit the role of aggregation metrics in order to mitigate polarization in a complex society. Our sociophysics model is based on interacting and nonlinear Brownian agents, which allow us to study the emergence of collective opinions. The opinion of an agent, x i (t) is a continuous positive value in an interval [0, 1]. We find (i) most agent-metrics display similar outcomes. (ii) The middle-metric and noisy-metric obtain new opinion dynamics either towards assimilation or fragmentation. (iii) We show that a developed 2-stage metric provide new insights about convergence and equilibria. In summary, our simulation demonstrates the power of institutions, which affect the emergence of collective behavior. Consequently, opinion formation in a decentralized complex society is reliant to the individual information processing and rules of collective behavior.
Intracranial brain tumors are one of the ten most common malignant cancers and account for substantial morbidity and mortality. The largest histological category of primary brain tumors is the gliomas which occur with an ultimate heterogeneous appearance and can be challenging to discern radiologically from other brain lesions. Neurosurgery is mostly the standard of care for newly diagnosed glioma patients and may be followed by radiation therapy and adjuvant temozolomide chemotherapy.
However, brain tumor surgery faces fundamental challenges in achieving maximal tumor removal while avoiding postoperative neurologic deficits. Two of these neurosurgical challenges are presented as follows. First, manual glioma delineation, including its sub-regions, is considered difficult due to its infiltrative nature and the presence of heterogeneous contrast enhancement. Second, the brain deforms its shape, called “brain shift,” in response to surgical manipulation, swelling due to osmotic drugs, and anesthesia, which limits the utility of pre-operative imaging data for guiding the surgery.
Image-guided systems provide physicians with invaluable insight into anatomical or pathological targets based on modern imaging modalities such as magnetic resonance imaging (MRI) and Ultrasound (US). The image-guided toolkits are mainly computer-based systems, employing computer vision methods to facilitate the performance of peri-operative surgical procedures. However, surgeons still need to mentally fuse the surgical plan from pre-operative images with real-time information while manipulating the surgical instruments inside the body and monitoring target delivery. Hence, the need for image guidance during neurosurgical procedures has always been a significant concern for physicians.
This research aims to develop a novel peri-operative image-guided neurosurgery (IGN) system, namely DeepIGN, that can achieve the expected outcomes of brain tumor surgery, thus maximizing the overall survival rate and minimizing post-operative neurologic morbidity. In the scope of this thesis, novel methods are first proposed for the core parts of the DeepIGN system of brain tumor segmentation in MRI and multimodal pre-operative MRI to the intra-operative US (iUS) image registration using the recent developments in deep learning. Then, the output prediction of the employed deep learning networks is further interpreted and examined by providing human-understandable explainable maps. Finally, open-source packages have been developed and integrated into widely endorsed software, which is responsible for integrating information from tracking systems, image visualization, image fusion, and displaying real-time updates of the instruments relative to the patient domain.
The components of DeepIGN have been validated in the laboratory and evaluated in the simulated operating room. For the segmentation module, DeepSeg, a generic decoupled deep learning framework for automatic glioma delineation in brain MRI, achieved an accuracy of 0.84 in terms of the dice coefficient for the gross tumor volume. Performance improvements were observed when employing advancements in deep learning approaches such as 3D convolutions over all slices, region-based training, on-the-fly data augmentation techniques, and ensemble methods.
To compensate for brain shift, an automated, fast, and accurate deformable approach, iRegNet, is proposed for registering pre-operative MRI to iUS volumes as part of the multimodal registration module. Extensive experiments have been conducted on two multi-location databases: the BITE and the RESECT. Two expert neurosurgeons conducted additional qualitative validation of this study through overlaying MRI-iUS pairs before and after the deformable registration. Experimental findings show that the proposed iRegNet is fast and achieves state-of-the-art accuracies. Furthermore, the proposed iRegNet can deliver competitive results, even in the case of non-trained images, as proof of its generality and can therefore be valuable in intra-operative neurosurgical guidance.
For the explainability module, the NeuroXAI framework is proposed to increase the trust of medical experts in applying AI techniques and deep neural networks. The NeuroXAI includes seven explanation methods providing visualization maps to help make deep learning models transparent. Experimental findings showed that the proposed XAI framework achieves good performance in extracting both local and global contexts in addition to generating explainable saliency maps to help understand the prediction of the deep network. Further, visualization maps are obtained to realize the flow of information in the internal layers of the encoder-decoder network and understand the contribution of MRI modalities in the final prediction. The explainability process could provide medical professionals with additional information about tumor segmentation results and therefore aid in understanding how the deep learning model is capable of processing MRI data successfully.
Furthermore, an interactive neurosurgical display has been developed for interventional guidance, which supports the available commercial hardware such as iUS navigation devices and instrument tracking systems. The clinical environment and technical requirements of the integrated multi-modality DeepIGN system were established with the ability to incorporate: (1) pre-operative MRI data and associated 3D volume reconstructions, (2) real-time iUS data, and (3) positional instrument tracking. This system's accuracy was tested using a custom agar phantom model, and its use in a pre-clinical operating room is simulated. The results of the clinical simulation confirmed that system assembly was straightforward, achievable in a clinically acceptable time of 15 min, and performed with a clinically acceptable level of accuracy.
In this thesis, a multimodality IGN system has been developed using the recent advances in deep learning to accurately guide neurosurgeons, incorporating pre- and intra-operative patient image data and interventional devices into the surgical procedure. DeepIGN is developed as open-source research software to accelerate research in the field, enable ease of sharing between multiple research groups, and continuous developments by the community. The experimental results hold great promise for applying deep learning models to assist interventional procedures - a crucial step towards improving the surgical treatment of brain tumors and the corresponding long-term post-operative outcomes.
This paper presents a description model for smart, connected devices used in a manufacturing context. Similar to the wide spread adoption of smart products for personal and private usage, recent developments lead to a plethora of devices offering a variety of features and capabilities. Manufacturing companies undergoing digital transformation demand guidance with respect to the systematic introduction of smart, connected devices. The introduction of smart connected devices constitutes a strategic decision cost due to the high future committed cost after introduction and maintaining a smart device fleet by a vendor. This paper aims to support the introduction efforts by classifying the devices and thus helping companies identify their specific requirements for smart, connected devices before initiating widespread procurement. By mapping the features of these devices based on various attributes, allows the clustering of smart, connected devices including a requirement list for their implementation on the shopfloor. Four individual commercially available smart connected devices were analyzed using the description model.
Parallel grippers offer multiple applications thanks to their flexibility. Their application field ranges from aerospace and automotive to medicine and communication technologies. However, the application of grippers has the problem of exhibition wear and errors during the execution of their operation. This affects the performance of the gripper. In this context, the remaining useful life (RUL) defines the remaining lifespan until failure for an asset at a particular time of operation occurs. The exact lifespan of an asset is uncertain, thus the RUL model and estimation must be derived from available sources of information. This paper presents a method for the estimation of the RUL for a two-jaw parallel gripper. After the introduction to the topic, an overview of existing literature and RUL methods are presented. Subsequently, the method for estimating the RUL of grippers is explained. Finally, the results are summarized and discussed before the outlook and further challenges are presented.
AI-based prediction and recommender systems are widely used in various industry sectors. However, general acceptance of AI-enabled systems is still widely uninvestigated. Therefore, firstly we conducted a survey with 559 respondents. Findings suggested that AI-enabled systems should be fair, transparent, consider personality traits and perform tasks efficiently. Secondly, we developed a system for the Facial Beauty Prediction (FBP) benchmark that automatically evaluates facial attractiveness. As our previous experiments have proven, these results are usually highly correlated with human ratings. Consequently they also reflect human bias in annotations. An upcoming challenge for scientists is to provide training data and AI algorithms that can withstand distorted information. In this work, we introduce AntiDiscriminationNet (ADN), a superior attractiveness prediction network. We propose a new method to generate an unbiased convolutional neural network (CNN) to improve the fairn ess of machine learning in facial dataset. To train unbiased networks we generate synthetic images and weight training data for anti-discrimination assessments towards different ethnicities. Additionally, we introduce an approach with entropy penalty terms to reduce the bias of our CNN. Our research provides insights in how to train and build fair machine learning models for facial image analysis by minimising implicit biases. Our AntiDiscriminationNet finally outperforms all competitors in the FBP benchmark by achieving a Pearson correlation coefficient of PCC = 0.9601.
Digital twins deployed in production are important in practice and interesting for research. Currently, mostly structured data coming from e.g., sensors and timestamps of related stations, are integrated into Digital Twins. However, semi- and unstructured data are also important to display the current status of a digital twin (e.g., of a machinery or produced good). Process Mining and Text Mining in combination can be used to support the use of log file data to understand the current state of the process as well as highlight issues. Therefore, issue related reactions can be taken more quickly, targeted and cost oriented. Applying a design science research approach; here a prototype as an artefact based on derived requirements is developed. This prototype helps to understand and to clarify the possibilities of Process Mining and Text Mining based on log data for production related Digital Twins. Contributions for practice and research are described. Furthermore, limitations of the research and future opportunities are pointed out.
Non-fungible tokens (NFTs) are unique digital assets that have recently gained significant popularity, particularly in the digital art sector. The success of NFTs and other blockchain-based innovations depends on their ac-acceptance and use by consumers. This study aims to understand the impact of moral values on the acceptance of NFTs. Based on a quantitative survey with over 800 complete responses, the analysis shows that moral aspects of NFTs are indeed important for potential users. However, there is an attitude-behavior gap, as the positive impact of moral values on the intention to use NFTs is not reflected in the actual current usage of NFTs by the respondents. This study contributes to knowledge by providing new empirical data on the acceptance of NFTs and highlighting the role of moral values on the acceptance decision.