Generation of an azide-modified extracellular matrix by adipose-derived stem cells using metabolic glycoengineering
- Natural extracellular matrix (ECM) represents an ideal biomaterial for tissue engineering and regenerative medicine approaches. For further functionalization, there is a need for specific addressable functional groups within this biomaterial. Metabolic glycoengineering (MGE) provides a technique to incorporate modified monosaccharide derivatives into the ECM during their assembly, which was shown by us earlier for the production of a modified fibroblast-derived dermal ECM.
Author of HS Reutlingen | Nellinger, Svenja; Volz, Ann-Cathrin; Kluger, Petra |
---|---|
URN: | urn:nbn:de:bsz:rt2-opus4-25648 |
DOI: | https://doi.org/10.1515/cdbme-2019-0099 |
ISSN: | 2364-5504 |
Erschienen in: | Current directions in biomedical engineering |
Publisher: | De Gruyter |
Place of publication: | Berlin |
Document Type: | Journal article |
Language: | English |
Publication year: | 2019 |
Tag: | adipose-derived stem cells; azide-modified; clickECM; extracellular matrix; metabolic glycoengineering |
Volume: | 5 |
Issue: | 1 |
Page Number: | 4 |
First Page: | 393 |
Last Page: | 396 |
DDC classes: | 570 Biowissenschaften, Biologie |
Open access?: | Ja |
Licence (German): | ![]() |