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Business process management and IT supported processes are an actual topic. The procedure of finding a business process system that implements your processes the best way is not easy and takes a lot of time. In this article you will find a recommendation for an open source system. Four selected open source workflow management systems are tested and analyzed. Mean criteria for the evaluation are listed in a criteria catalogue and rated by experts by their importance. Finally, the systems are evaluated by the criteria and the best evaluated system can be recommended.
The question of why individuals adopt information technology has been present in the information systems research since the past quarter century. One of the most used models for predicting the technology usage was introduced by Fred David: The Technology Acceptance Model (TAM). It describes the influence of perceived usefulness and perceived ease of use on attitude, behavioral intention and system usage. The first two mentioned factors in turn are influenced by external variables. Although a plethora of papers exists about the TAM , an extensive analysis of the role of the external variables in the model is still missing. This paper aims to give an overview ove the most important variables. In an extensive literature review, we identified 763 relevant papers, found 552 unique single extenal variables, characterized the most important of them, and described the frequency of their appearance. Additionally, we grouped these variables into four categories (organizational characteristis, system characteristics, user personal characteristics, and other variables). Afterwards we discuss the results and show implications for theory and practice.
Bei weitgehend gleicher Ausstattung und neuen Anforderungen an die Hochschulrechenzentren rücken Kooperationen zunehmend in den Mittelpunkt. Für diese,
auch hochschulartenübergreifende, Kooperationen genügt der klassische informelle Rahmen vielfach nicht mehr. Für eine erfolgreiche Zusammenarbeit sind einige Voraussetzungen zu erfüllen. Rechenzentren treten in neuer Rolle als Provider von Dienstleistungen für Nutzer auch außerhalb ihrer eigenen Hochschule auf. Ebenso
könnten sie sich zukünftig verstärkt in der Nutzerperspektive wiederfinden. IT-Service-Einrichtungen müssen sich ihrer neuen Rolle als Diensteanbieter und Nutzer von Diensten Dritter bewusst werden und diese in ihre Überlegungen für die Ausgestaltung neuer Dienste einfließen lassen.
Marketing-Events emotionalisieren das Publikum auf besondere Art und Weise. Einstellungsänderungen bzw. Imageverbesserungen stellen deshalb die zentralen Zielsetzungen des Event-Marketing dar. Aufbauend auf den wesentlichen Grundlagen des Event-Marketing fokussiert dieses Kapitel auf das Controlling im Event-Marketing. Eingegangen wird auf die Erfolgskontrolle und die Wirkungsforschung im Event-Marketing. Es werden die Bedingungen für das Zustandekommen eines Imagetransfers von einem Event auf eine Marke bzw. ein Unternehmen erläutert und Verfahren zur Imagemessung vorgestellt.
Instead of waiting for and constantly adapting to details of political interventions, utilities need to focus on their environment from a holistic perspective. The unique position of the company - be it a local utility, a bigger player, or an international utility specializing in specitic segments - has to be the basis of goals and strategies. But without consistent translation of these goals and strategies into processes, structures, and company culture, a strategy remains pure theory. Companies need to engage in a continuing learning process. This means being willing to pass on strategies, to slow down or speed up, to work from a different angle etc.
The reduced research and development (R&D) efficiency, strong competition from generics, increased cost pressure from payers, and an increased biological complexity of new target indications have resulted in a rethinking and a change from a traditional and more closed R&D model in the pharmaceutical industry toward the new paradigm of open innovation. In the past years, pharmaceutical companies have broadened their external networks toward research collaborations with academic institutes, technology providers, or codevelopment partners. To fulfill the demand to reduce timelines and costs, research-based pharmaceutical companies started to outsource R&D activities. In addition, internal R&D processes were adjusted to the more open R&D model and new processes such as alliance management were established. The corporate frontier of pharmaceutical companies became permeable and more open. As a result, the focus of pharmaceutical R&D expanded from a purely internal toward a mixed internal and external model. Today, the U.S. pharmaceutical company Eli Lilly may have established the most open model toward external innovation, as it has integrated its innovation processes with its business model. Other companies are following this more open R&D model with newer concepts such as new frontier sciences, drug discovery alliances, private public partnerships, innovation incubators, virtual R&D, crowdsourcing, open source innovation, and innovation camps.
Clinical development is historically the phase in which a potential new medicine is being tested in phase 2 and phase 3 patient trials to demonstrate the new molecules' efficacy and safety to support the regulatory approval of drugs by health authorities. This relatively focused approach has been considerably expanded by a number of forces from within the pharmaceutical industry and equally important by changes in the healthcare systems. The need to identify the optimal patient population, showstoppers leading to discontinuation of clinical programs, the silent but constant removal of surrogate endpoints for registration, and the increased demand for real-life data which are used to demonstrate the patients' benefit and which have an ever-increasing role for pricing and reimbursement negotiations are today an integral part of this phase.
This chapter will review both the nuts and bolts of clinical development but also recent developments in this area which shape the environment and how the different players have reacted and what options might need to be explored in the future.
Virtual prototyping of integrated mixed-signal smart sensor systems requires high-performance co-simulation of analog frontend circuitry with complex digital controller hardware and embedded real-time software. We use SystemC/TLM 2.0 in conjunction with a cycle-count accurate temporal decoupling approach (TD) to simulate digital components and firmware code execution at high speed while preserving clock-cycle accuracy and, thus, real-time behavior at time quantum boundaries. Optimal time quanta ensuring real-time capability can be calculated and set automatically during simulation if the simulation engine has access to exact timing information about upcoming inter-process communication events. These methods fail in the case of non-deterministic, asynchronous events, resulting in potentially invalid simulation results. In this paper, we propose an extension to the case of asynchronous events generated by blackbox sources from which a priori event timing information is not available, such as coupled analog simulators or hardware in the loop. Additional event processing latency or rollback effort caused by temporal decoupling is minimized by calculating optimal time quanta dynamically in a SystemC model using a linear prediction scheme. We analyze the theoretical performance of the presented predictive temporal decoupling approach (PTD) by deriving a cost model that expresses the expected simulation effort in terms of key parameters such as time quantum size and CPU time per simulation cycle. For an exemplary smart-sensor system model, we show that quasi-periodic events that trigger activities in TD processes are handled accurately after the predictor has settled.
The Internet of Things (IoT) refers to the interconnectedness of physical objects, and works by equipping the latter with sensors and actuators as a means to connect to the internet. The number of connected things has increased threefold over the past five years. Consequently, firms expect the IoT to become a source of new business models driven by technology. However, only a few early adopters have started to install and use IoT appliances on a frequent basis. So it is still unclear which factors drive technological acceptance of IoT appliances. Confronting this gap in current research, the present paper explores how IoT appliances are conceptually defined, which factors drive technological acceptance of IoT appliances, and how firms can use results in order to improve value propositions in corresponding business models. lt is discovered that IoT appliance vendors need to support a broad focus as the potential buyers expose a large variety. As conclusions from this insight, the paper illustrates some flexible marketing strategies.
Despite 30 years of Electronic Design Automation, analog IC layouts are still handcrafted in a laborious fashion today due to the complex challenge of considering all relevant design constraints. This paper presents Self-organized Wiring and Arrangement of Responsive Modules (SWARM), a novel approach addressing the problem with a multi-agent system: autonomous layout modules interact with each other to evoke the emergence of overall compact arrangements that fit within a given layout zone. SWARM´s unique advantage over conventional optimization-based and procedural approaches is its ability to consider crucial design constraints both explicitly and implicitly. Several given examples show that by inducing a synergistic flow of self-organization, remarkable layout results can emerge from SWARM’s decentralized decision-making model.
Besides the optimisation of the car, energy-efficiency and safety can also be increased by optimising the driving behaviour. Based on this fact, a driving system is in development whose goal is to educate the driver in energy efficient and safe driving. It monitors the driver, the car and the environment and gives energy-efficiency and safety relevant recommendations. However, the driving system tries not to distract or bother the driver by giving recommendations for example during stressful driving situations or when the driver is not interested in that recommendation. Therefore, the driving system monitors the stress level of the driver as well as the reaction of the driver to a given recommendation and decideswhether to give a recommendation or not. This allows to suppress recommendations when needed and, thus, to increase the road safety and the user acceptance of
the driving system.
Stress is becoming an important topic in modern life. The influence of stress results in a higher rate of health disorders such as burnout, heart problems, obesity, asthma, diabetes, depressions and many others. Furthermore individual’s behavior and capabilities could be directly affected leading to altered cognition, inappropriate decision making and problem solving skills. In a dynamic and unpredictable environment, such as automotive, this can result in a higher risk for accidents. Different papers faced the estimation as well as prediction of drivers’ stress level during driving. Another important question is not only the stress level of the driver himself, but also the influence on and of a group of other drivers in the near area. This paper proposes a system, which determines a group of drivers in a near area as clusters and it derives the individual stress level. This information will be analyzed to generate a stress map, which represents a graphical view about road section with a higher stress influence. Aggregated data can be used to generate navigation routes with a lower stress influence to decrease stress influenced driving as well as improve road safety.
Stress is recognized as a predominant disease with raising costs for rehabilitation and treatment. Currently there are several different approaches that can be used for determining and calculating the stress levels. Usually the methods for determining stress are divided in two categories. The first category do not require any special equipment for measuring the stress. This category useless the variation in the behaviour patterns that occur while stress. The core disadvantage for the category is their limitation to specific use case. The second category uses laboratories instruments and biological sensors. This category allow to measure stress precisely and proficiently but on the same time they are not mobile and transportable and do not support real-time feedback. This work presents a mobile system that provides the calculation of stress. For achieving this, the of a mobile ECG sensor is analysed, processed and visualised over a mobile system like a smartphone. This work also explains the used stress measurement algorithm. The result of this work is a portable system that can be used with a mobile system like a smartphone as visual interface for reporting the current stress level.
As long as there have been professional sports, there have been relationships on different levels. For example, sponsorship (or patronage as it was called in the early days) was mostly based on personal relations between the local benefactors and their favourite sports club. Regarding media, clubs always maintained special relationships with selected journalists. The bond between fans and their clubs was always a close and mutually beneficial one. All these relationships existed from the start of the sports business. Therefore, relationship marketing is nothing new in the context of sports. Many sporting organisations always knew to value a deep and good relationship with their stakeholders and practised relationship marketing without being aware of it. Successful sports managers, however, take the old wisdom and turn it into a modern relationship marketing approach by structuring the various relationships in order to make them more effective and profitable for the own sporting organisation and the various stakeholders. This chapter ... illustrates the many facets of relationship marketing and the possibilities it offers in the context of the sports business.
Reality mining refers to an application of data mining, using sensor data to drive behavioral patterns in the real world. However, research in this field started a decade ago when technology was far behind today's state of the art. This paper discusses which requirements are now posed to applications in the context of reality mining. A survey has shown which sensors are available in state-of-the-art smartphones and usable to gather data for reality mining. As another contribution of this paper, a reality mining application architecture is proposed to facilitate the implementation of such applications. A proof of concept verifies the assumptions made on reality mining and the presented architecture.
Pultrusion of braids
(2016)
We have seen that bionic optimization can be a powerful tool when applied to problems with non-trivial landscapes of goals and restrictions. This, in turn, led us to a discussion of useful methodologies for applying this optimization to real problems. On the other hand, it must be stated that each optimization is a time consuming process as soon as the problem expands beyond a small number of free parameters related to simple parabolic responses. Bionic optimization is not a quick approach to solving complex questions within short times. In some cases it has the potential to fail entirely, either by sticking to local maxima or by random exploration of the parameter space without finding any promising solutions. The following sections present some remarks on the efficiency and limitations users must be aware of. They aim to increase the knowledge base of using and encountering bionic optimization. But they should not discourage potential users from this promising field of powerful strategies to find good or even the best possible designs.
Der Beitrag erweitert aus der theoretischen Perspektive der Soziologie der Konventionen (Économie des Conventions, EC) die Forschung zur pragmatischen Dimension des organisationalen Gedächtnisses. Dabei wird erstens argumentiert, dass Konventionen als organisationales Gedächtnis verstanden werden können, in denen gespeichert wird, wie Koordinationsprobleme erfolgreich lösbar sind. Zweitens wird anhand des Akteurstatus der EC sowie des Konzepts der Handlungsregime diskutiert, wie Akteure auf gespeichertes Wissen zugreifen. Und drittens wird die bislang nicht berücksichtigte normative Dimension des organisationalen Gedächtnisses analysiert. Dabei wird argumentiert, dass Akteure sich auf Konventionen gestützt rechtfertigen, wenn sie Elemente des organisationalen Gedächtnisses aufgreifen. Insgesamt trägt der Beitrag dazu bei, die Verbindung von kollektivem Gedächtnis und Entscheidung besser zu verstehen, indem sie auf Basis der EC als eine interaktionistische, pragmatische und normativ geprägte Aushandlung von Erinnerungen in konkreten Situationen betrachtet wird.
The efficiency of pharmaceutical research and development (R&D) reflected by increasing costs of R&D, long timelines, and low probabilities of technical and regulatory success decreased continuously in the past years. Today, the costs for discovering and developing a new drug are enormously high with more than USD 2 billion per new molecular entity (NME), while the average overall success of a research project to provide an NME is in the single-digit percentage rate, and the total timelines of R&D easily exceeds 10 years questioning the return on investment (ROI) of pharmaceutical R&D. As a consequence and also caused by numerous patent expirations of blockbuster drugs that increased the pressure to return to an acceptable ROI, the pharmaceutical industry addressed this challenge and the related causes and identified several actions that need to be taken to increase the output/input ratio of R&D. This book chapter will review the pipeline sizes and the R&D investments of multinational pharmaceutical companies, will describe new processes that have been implemented to increase the reach and to reduce costs of pharmaceutical R&D, and it will illustrate new innovation models that were developed to increase the R&D efficiency.