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Salivary gland tumors (SGTs) are a relevant, highly diverse subgroup of head and neck tumors whose entity determination can be difficult. Confocal Raman imaging in combination with multivariate data analysis may possibly support their correct classification. For the analysis of the translational potential of Raman imaging in SGT determination, a multi-stage evaluation process is necessary. By measuring a sample set of Warthin tumor, pleomorphic adenoma and non-tumor salivary gland tissue, Raman data were obtained and a thorough Raman band analysis was performed. This evaluation revealed highly overlapping Raman patterns with only minor spectral differences. Consequently, a principal component analysis (PCA) was calculated and further combined with a discriminant analysis (DA) to enable the best possible distinction. The PCA-DA model was characterized by accuracy, sensitivity, selectivity and precision values above 90% and validated by predicting model-unknown Raman spectra, of which 93% were classified correctly. Thus, we state our PCA-DA to be suitable for parotid tumor and non-salivary salivary gland tissue discrimination and prediction. For evaluation of the translational potential, further validation steps are necessary.
Im Team zum fliegenden Traum
(2024)
Purpose
As a response to the increased frequency of disruptive events and intense competition, organizational agility has become a key concept in organizational research. Fostering organizational agility requires leveraging knowledge that exists both outside (exploration) and inside (exploitation) the organization. This research tests the so-called ambidexterity hypothesis, which claims that a balance between exploration and exploitation leads to increased organizational outcomes, including the development of organizational agility. Complementing previously established measurement models on ambidexterity, this research proposes an alternative measurement model to analyze how ambidexterity can enhance organizational agility and, indirectly, performance, taking into consideration the moderating effect of environmental competitiveness.
Design/methodology/approach
A review of existing measurement models for ambidexterity shows that tension, a crucial aspect of ambidexterity, is often neglected. The authors, therefore, develop a new measurement model of ambidexterity to incorporate ambidexterity-induced tension. Using this measurement model, they examine the effect of ambidexterity on the development of entrepreneurial and adaptive agility as well as performance.
Findings
Ambidexterity positively influences both entrepreneurial and adaptive agility, indicating that a balance between exploration and exploitation has superior organizational effects. This finding confirms the ambidexterity hypothesis with respect to organizational agility. Furthermore, both entrepreneurial and adaptive agility drive organizational performance. These two indirect effects via agility fully mediate the impact of ambidexterity on organizational performance. Finally, environmental competitiveness positively moderates the relationship between ambidexterity and adaptive agility.
Originality/value
The findings extend research on ambidexterity by showing its positive effects on organizational agility. Furthermore, the study proposes an alternative operationalization to capture the ambidexterity construct that may lay the groundwork for further applications of the ambidexterity concept.
Software scripts for sensor data extraction in Rasberry Pi: user-space and kernel-space comparison
(2024)
This paper compares two popular scripting implementations for hardware prototyping: Python scripts execut from User-Space and C-based Linux-Driver processes executed from Kernel-Space, which can provide information to researchers when considering one or another in their implementations. Conclusions exhibit that deploying software scripts in the kernel space makes it possible to grant a certain quality of sensor information using a Raspberry Pi without the need for advanced real-time operational systems.
Accurate monitoring of a patient's heart rate is a key element in the medical observation and health monitoring. In particular, its importance extends to the identification of sleep-related disorders. Various methods have been established that involve sensor-based recording of physiological signals followed by automated examination and analysis. This study attempts to evaluate the efficacy of a non-invasive HR monitoring framework based on an accelerometer sensor specifically during sleep. To achieve this goal, the motion induced by thoracic movements during cardiac contractions is captured by a device installed under the mattress. Signal filtering techniques and heart rate estimation using the symlets6 wavelet are part of the implemented computational framework described in this article. Subsequent analysis indicates the potential applicability of this system in the prognostic domain, with an average error margin of approximately 3 beats per minute. The results obtained represent a promising advancement in non-invasive heart rate monitoring during sleep, with potential implications for improved diagnosis and management of cardiovascular and sleep-related disorders.
The massive use of patient data for the training of artificial intelligence algorithms is common nowadays in medicine. In this scientific work, a statistical analysis of one of the most used datasets for the training of artificial intelligence models for the detection of sleep disorders is performed: sleep health heart study 2. This study focuses on determining whether the gender and age of the patients have a relevant influence to consider working with differentiated datasets based on these variables for the training of artificial intelligence models.
Human pose estimation (HPE) is integral to scene understanding in numerous safety-critical domains involving human-machine interaction, such as autonomous driving or semi-automated work environments. Avoiding costly mistakes is synonymous with anticipating failure in model predictions, which necessitates meta-judgments on the accuracy of the applied models. Here, we propose a straightforward human pose regression framework to examine the behavior of two established methods for simultaneous aleatoric and epistemic uncertainty estimation: maximum a-posteriori (MAP) estimation with Monte-Carlo variational inference and deep evidential regression (DER). First, we evaluate both approaches on the quality of their predicted variances and whether these truly capture the expected model error. The initial assessment indicates that both methods exhibit the overconfidence issue common in deep probabilistic models. This observation motivates our implementation of an additional recalibration step to extract reliable confidence intervals. We then take a closer look at deep evidential regression, which, to our knowledge, is applied comprehensively for the first time to the HPE problem. Experimental results indicate that DER behaves as expected in challenging and adverse conditions commonly occurring in HPE and that the predicted uncertainties match their purported aleatoric and epistemic sources. Notably, DER achieves smooth uncertainty estimates without the need for a costly sampling step, making it an attractive candidate for uncertainty estimation on resource-limited platforms.
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Automatic content creation system for augmented reality maintenance applications for legacy machines
(2024)
Augmented reality (AR) applications have great potential to assist maintenance workers in their operations. However, creating AR solutions is time-consuming and laborious, which limits its widespread adoption in the industry. It therefore often happens that even with the latest generation machines, instead of an AR solution, the user only receives an electronic manual for the equipment operation and maintenance. This is commonplace with legacy machines. For this reason, solutions are required that simplify the creation of such AR solutions. This paper presents an approach using an electronic manual as a basis to create fast and cost-effective AR solutions for maintenance. As part of the approach, an application was developed to automatically identify and subdivide the chapters of electronic manuals via the bookmarks in the table of contents. The contents are then automatically uploaded to a central server and indexed with a suitable marker to make the data retrievable. The prepared content can then be accessed for creating context-related AR instructions via the marker. The application is characterized by the fact that no developers or experts are required to prepare the information. In addition to complying with common design criteria, the clear presentation of the contents and the intuitive use of the system offer added value for the performance of maintenance tasks. Together, these two elements form a novel way to retrofit legacy machines with AR maintenance instructions. The practical validation of the system took place in a factory environment. For this purpose, the content was created for a filter change on a CNC milling machine. The results show that inexperienced users can extract appropriate content with the software application. Furthermore, it is shown that maintenance workers, can access the content with an AR application developed for the Microsoft HoloLens 2 and complete simple tasks provided in the manufacturer's electronic manual.
Evaluation of a contactless accelerometer sensor system for heart rate monitoring during sleep
(2024)
The monitoring of a patient's heart rate (HR) is critical in the diagnosis of diseases. In the detection of sleep disorders, it also plays an important role. Several techniques have been proposed, including using sensors to record physiological signals that are automatically examined and analysed. This work aims to evaluate using a contactless HR monitoring system based on an accelerometer sensor during sleep. For this purpose, the oscillations caused by chest movements during heart contractions are recorded by an installation mounted under the bed mattress. The processing algorithm presented in this paper filters the signals and determines the HR. As a result, an average error of about 5 bpm has been documented, i.e., the system can be considered to be used for the forecasted domain.