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With the digital transformation, companies will experience a change that focuses on shaping the organization into an agile organizational form. In today's competitive and fast-moving business environment, it is necessary to react quickly to changing market conditions. Agility represents a promising option for overcoming these challenges. The path to an agile organization represents a development process that requires consideration of countless levels of the enterprise. This paper examines the impact of digital transformation on agile working practices and the benefits that can be achieved through technology. To enable a solution for today's so-called VUCA (Volatility, Uncertainty, Complexity und Ambiguity) world, agile ways of working can be applied project management requires adaptation. In the qualitative study, expert interviews were conducted and analyzed using the grounded theory method. As a result, a model can be presented that shows the influencing factors and potentials of agile management in the context of the digital transformation of medium-sized companies.
Industrial practice is characterized by random events, also referred to as internal and external turbulences, which disturb the target-oriented planning and execution of production and logistics processes. Methods of probabilistic forecasting, in contrast to single value predictions, allow an estimation of the probability of various future outcomes of a random variable in the form of a probability density function instead of predicting the probability of a specific single outcome. Probabilistic forecasting methods, which are embedded into the analytics process to gain insights for the future based on historical data, therefore offer great potential for incorporating uncertainty into planning and control in industrial environments. In order to familiarize students with these potentials, a training module on the application of probabilistic forecasting methods in production and intralogistics was developed in the learning factory 'Werk150' of the ESB Business School (Reutlingen University). The theoretical introduction to the topic of analytics, probabilistic forecasting methods and the transition to the application domain of intralogistics is done based on examples from other disciplines such as weather forecasting and energy consumption forecasting. In addition, data sets of the learning factory are used to familiarize the students with the steps of the analytics process in a practice-oriented manner. After this, the students are given the task of identifying the influencing factors and required information to capture intralogistics turbulences based on defined turbulence scenarios (e.g. failure of a logistical resource) in the learning factory. Within practical production scenario runs, the students apply probabilistic forecasting using and comparing different probabilistic forecasting methods. The graduate training module allows the students to experience the potentials of using probabilistic forecasting methods to improve production and intralogistics processes in context with turbulences and to build up corresponding professional and methodological competencies.
Especially, if the potential of technical and organizational measures for ergonomic workplace design is limited, exoskeletons can be considered as innovative ergonomic aids to reduce the physical workload of workers. Recent scientific findings from ergonomic analyses with and without exoskeletons are indicating that strain reduction can be achieved, particularly at workplaces with lifting, holding, and carrying processes. Currently, a work system design method is under development incorporating criteria and characteristics for the design of work systems in which a human worker is supported by an exoskeleton. Based on the properties of common passive and active exoskeletons, factors influencing the human on which an exoskeleton can have a positive or negative effect (e.g. additional weight) were derived. The method will be validated by the conceptualization and setup of several work system demonstrators at Werk150, the factory of ESB Business School on campus of Reutlingen University, to prove the positive ergonomic effect on humans and the supporting process to choose the suitable exoskeleton. The developed method and demonstrators enable the user to experience the positive ergonomic effects of exoskeletal support in lifting, holding and carrying processes in logistics and production. The new work system design method will contribute to the fact that employees can pursue their professional activity longer without substantial injuries or can be used more flexibly at different work stations. Also new work concepts, strategies and scenarios are opened up to reduce the risk of occupational accidents and to promote the compatibility of work for employees. A training module is being developed and evaluated with participants from industry and master students to build up competence.
The early involvement of experiences gained through intelligence and data analysis is becoming increasingly important in order to develop new products, leading to a completely different conception of product creation, development and engineering processes using the advantages that the dedication of the digital twin entails. Introducing a novel stage gate process in order to be holistically anchored in learning factories adopting idea generation and idea screening in an early stage, beta testing of first prototypes, technical implementation in real production scenarios, business analysis, market evaluation, pricing, service models as well as innovative social media portals. Corresponding product modelling in the sense of sustainability, circular economy, and data analytics forecasts the product on the market both before and after market launch with the interlinking of data interpretation nearby in real-time. The digital twin represents the link between the digital model and the digital shadow. Additionally, the connection of the digital twin with the product provides constantly updated operating status and process data as well as mapping of technical properties and real-world behaviours. A future-networking product, by embedded information technology with the ability to initiate and carry out one's own further development, is able to interact with people and environments and thus is relevant to the way of life of future generations. In today's development work for this new product creation approach, on one hand, "Werk150" is the object of the development itself and on the other hand the validation environment. In the next step, new learning modules and scenarios for trainings at master level will be derived from these findings.
The use of deep learning models with medical data is becoming more widespread. However, although numerous models have shown high accuracy in medical-related tasks, such as medical image recognition (e.g. radiographs), there are still many problems with seeing these models operating in a real healthcare environment. This article presents a series of basic requirements that must be taken into account when developing deep learning models for biomedical time series classification tasks, with the aim of facilitating the subsequent production of the models in healthcare. These requirements range from the correct collection of data, to the existing techniques for a correct explanation of the results obtained by the models. This is due to the fact that one of the main reasons why the use of deep learning models is not more widespread in healthcare settings is their lack of clarity when it comes to explaining decision making.
Nowadays, the importance of early active patient mobilization in the recovery and rehabilitation phase has increased significantly. One way to involve patients in the treatment is a gamification-like approach, which is one of the methods of motivation in various life processes. This article shows a system prototype for patients who require physical activity because of active early mobilization after medical interventions or during illness. Bedridden patients and people with a sedentary lifestyle (predominantly lying in bed) are also potential users. The main idea for the concept was non-contact system implementation for the patients making them feel effortless during its usage. The system consists of three related parts: hardware, software, and game application. To test the relevance and coherence of the system, it was used by 35 people. The participants were asked to play a video game requiring them to make body movements while lying down. Then they were asked to take part in a small survey to evaluate the system's usability. As a result, we offer a prototype consisting of hardware and software parts that can increase and diversify physical activity during active early mobilization of patients and prevent the occurrence of possible health problems due to predominantly low activity. The proposed design can be possibly implemented in hospitals, rehabilitation centers, and even at home.
Healthy sleep is required for sufficient restoration of the human body and brain. Therefore, in the case of sleep disorders, appropriate therapy should be applied timely, which requires a prompt diagnosis. Traditionally, a sleep diary is a part of diagnosis and therapy monitoring for some sleep disorders, such as cognitive behaviour therapy for insomnia. To automatise sleep monitoring and make it more comfortable for users, substituting a sleep diary with a smartwatch measurement could be considered. With the aim of providing accurate results, a study with a total of 30 night recordings was conducted. Objective sleep measurement with a Samsung Galaxy Watch 4 was compared with a subjective approach (sleep diary), evaluating the four relevant sleep characteristics: time of getting asleep, wake up time, sleep efficiency (SE), and total sleep time (TST). The performed analysis has demonstrated that the median difference between both measurement approaches was equal to 7 and 3 minutes for a time of getting asleep and wake up time correspondingly, which allows substituting a subjective measurement with a smartwatch. The SE was determined with a median difference between the two measurement methods of 5.22%. This result also implicates a possibility of substitution. Some single recordings have indicated a higher variance between the two approaches. Therefore, the conclusion can be made that a substitution provides reliable results primarily in the case of long-term monitoring. The results of the evaluation of the TST measurement do not allow to recommend substitution of the measurement method.
Home health applications have evolved over the last few decades. Assistive systems such as a data platform in connection with health devices can allow for health-related data to be automatically transmitted to a database. However, there remain significant challenges concerning intermodular communication. Central among them is the challenge of achieving interoperability, the ability of devices to communicate and share data with each other. A major goal of this project was to extend an existing data platform (COMES®) and establish working interoperability by connecting assistive devices with differing approaches. We describe this process for a sleep monitoring and a physical exercise device. Furthermore, we aimed to test this setup and the implementation with a data platform in both a laboratory and an in-home setting with 11 elderly participants. The platform modification was realized, and the relevant changes were made so that the incoming data could be processed by the data platform, as well as visually displayed in real-time. Data was recorded by the respective device and transmitted into the data server with minor disruptions. Our observations affirmed that difficulties and data loss are far more likely to occur with increasing technical complexity, in the event of instable internet connection, or when the device setup requires (elderly) subjects to take specific steps for proper functioning. We emphasize the importance for tests and evaluations of home health technologies in real-life circumstances.
The citizen-centered health platform project is intended to provide a platform that can be used in EU cross-border regions, where social and economic exchange occurs across national borders. The overriding challenges are: (a) social: improving citizen-centered health and care provision; (b) technical: providing a digital platform for networking citizens, service providers, and municipal actors; (c) economic: developing long-term successful (sustainable) business models/value chains. The platform should strengthen and expand existing networks and establish new regional networks. Each network addresses particular challenges and apply them in a region-specific manner. Here, the national boundary conditions and the interregional needs play an essential role. These objectives require sufficient participation of civil society representatives. Furthermore, the platform will establish an overarching, sustainable, and knowledge-based network of health experts. The platform is to be jointly developed and implemented in the regions and follow an open-access approach. Therefore, synergies will be shared more quickly, strengthening competencies and competitiveness. In addition to practice partners, scientific and municipal institutions and SMEs are involved. The actors thus contribute to scientific performance, innovative strength, and resilience.
Modern production systems are characterized by the increasingly use of CPS and IoT networks. However, processing the available information for adaptation and reconfiguration often occurs in relatively large time cycles. It thus does not take advantage of the optimization potential available in the short term. In this paper, a concept is presented that, considering the process information of the individual heterogeneous system elements, detects optimization potentials and performs or proposes adaptation or reconfiguration. The concept is evaluated utilizing a case study in a learning factory. The resulting system thus enables better exploitation of the potentials of the CPPS.
Energy Communities explores core potential systemic benefits and costs in engaging consumers into communities, particularly relating to energy transition. The book evaluates the conditions under which energy communities might be regarded as customer-centered, market-driven and welfare-enhancing. The book also reviews the issue of prevalence and sustainability of energy communities and whether these features are likely to change as opportunities for distributed energy grow. Sections cover the identification of welfare considerations for citizens and for society on a local and national level, and from social, economic and ecological perspectives, while also considering different community designs and evolving business models.
The global demand for resources such as energy, land, or water is constantly increasing. It is therefore not sur- prising that research on the Food-Energy-Water (FEW) nexus has become a scientific as well as a general focus in recent years. A significant increase in publications since 2015 can be observed, and it can be expected that this trend will continue. A multilevel (macro, meso, and micro) perspective is essential, as the FEW nexus has cross- sectoral interdependencies. Several review studies on the FEW nexus can be found in the literature, in general, it can be concluded that the FEW nexus is a multi-disciplinary and complex topic. The studies examined identify essential fields of action for research, policy, and society. However, questions such as what are the main research fields at each level? Is it possible to divide the research into specific clusters? and do the clusters correlate with the levels, and what are the methods of modeling used in the clusters and levels? are still not fully discussed in the literature. An extensive literature review was conducted to get insight into the existing research areas. Especially in such fields as the FEW nexus, the amount of literature can get huge, and a human could get lost analyzing the literature manually. For that, we created word clouds and performed a cluster- and network-analysis to support the selection of most relevant papers for a detailed reading. In 2021, the most publications were published, with 173 publications, which corresponds to a share of 26.6 %. There has been a significant increase since 2015, and it can be expected that this trend will continue in the coming years. Most of the first authors come from the USA (25.4 %), followed by China with 22.4 %. From the word cloud and the top 20 words, which appear in the title and abstract, it can be deduced that the topic water is the most represented. However, the terms system, resource, model, study, change, development, and management also appear to be very important, which indi- cates the importance of a holistic approach to the topic. In total 9 clusters could be identified at the different levels. It can be seen that three clusters form well. For the others, a rather diffuse picture can be observed. In order to find out which topics are hidden behind the individual clusters, 6 publications from each cluster were subjected to a more detailed examination. With these steps, a number of 54 publications were identified for de- tailed consideration. The modeling approaches that are currently being applied in research can be classified into domain-specific tools (e. g. global water models, crop models or global climate models) and into more general tools to perform for example a life cycle analysis, spatial analysis using geographic information system, or system dynamics for a general understanding of the links between the domains. With the domain-specific tools, detailed research questions can be addressed to answer questions for a specific domain. However, these tools have the disadvantage that especially the links between the sectors food, energy, and water are not fully considered. Many implementations that are made today are at lowest level (micro) relate to bounded spatial areas and are derived from macro and meso level goals.
The transmembrane Ca2+ − activated Cl− channel - human bestrophin-1 (hBest1) is expressed in retinal pigment epithelium and mutations of BEST1 gene cause ocular degenerative diseases colectivelly referred to as “bestrophinopathies”. A large number of genetical, biochemical, biophysical and molecular biological studies have been performed to understand the relationship between structure and function of the hBest1 protein and its pathophysiological significance. Here, we review the current understanding of hBest1 surface organization, interactions with membrane lipids in model membranes, and its association with microdomains of cellular membranes. These highlights are significant for modulation of channel activity in cells.
Blockchain is a technology for the secure processing and verification of data transactions based on a distributed peer-to-peer network that uses cryptographic processes, consensus algorithms, and backward-linked blocks to make transactions virtually immutable. Within supply chain management, blockchain technology offer potentials in increasing supply chain transparency, visibility, automation, and efficiency. However, its complexity requires future employees to have comprehensive knowledge regarding the functionality of blockchain-based applications in order to be able to apply their benefits to scenarios in supply chain and production. Learning factories represent a suitable environment allowing learners to experience new technologies and to apply them to virtual and physical processes throughout value chains. This paper presents a concept to practically transfer knowledge about the technical functionality of blockchain technology to future engineers and software developers working within supply chains and production operations to sensitize them regarding the advantages of decentralized applications. First, the concept proposes methods to playfully convey immutable backward-linked blocks and the embedment of blockchain smart contracts. Subsequently, the students use this knowledge to develop blockchain-based application scenarios by means of an exemplary product in a learning factory environment. Finally, the developed solutions are implemented with the help of a prototypical decentralized application, which enables a holistic mapping of supply chain events.
The fifth mobile communications generation (5G) offers the deployment scenario of licensed 5G standalone non-public networks (NPNs). Standalone NPNs are locally restricted 5G networks based on 5G New Radio technology which are fully isolated from public networks. NPNs operate on their dedicated core network and offer organizations high data security and customizability for intrinsic network control. Especially in networked and cloud manufacturing, 5G is seen as a promising enabler for delay-sensitive applications such as autonomous mobile robots and robot motion control based on the tactile internet that requires wireless communication with deterministic traffic and strict cycling times. However, currently available industrial standalone NPNs do not meet the performance parameters defined in the 5G specification and standardization process. Current research lacks in performance measurements of download, upload, and time delays of 5G standalone-capable end-devices in NPNs with currently available software and hardware in industrial settings. Therefore, this paper presents initial measurements of the data rate and the round-trip delay in standalone NPNs with various end-devices to generate a first performance benchmark for 5G-based applications. In addition, five end-devices are compared to gain insights into the performance of currently available standalone-capable 5G chipsets. To validate the data rate, three locally hosted measurement methods, namely iPerf3, LibreSpeed and OpenSpeedTest, are used. Locally hosted Ping and LibreSpeed have been executed to validate the time delay. The 5G standalone NPN of Reutlingen University uses licensed frequencies between 3.7-3.8 GHz and serves as the testbed for this study.
Towards a model for holistic mapping of supply chains by means of tracking and tracing technologies
(2022)
The usage of tracking and tracing technologies not only enables transparency and visibility of supply chains but also offers far-reaching advantages for companies, such as ensuring product quality or reducing supplier risks. Increasing the amount of shared information supports both internal and external planning processes as well as the stability and resilience of globally operating value chains. This paper aims to differentiate and define the functionalities of tracking and tracing technologies that are frequently used interchangeably in literature. Furthermore, this paper incorporates influencing factors impacting a sequencing of the connected world in Industry4.0 supply chain networks. This includes legal influences, the embedment of supply chain-related standards, and new possibilities of emerging technologies. Finally, the results are summarized in a model for the holistic mapping of supply chains by means of tracking and tracing technologies. The resulting technological solutions that can be derived from the model enable companies to address missing elements in order to enable the holistic mapping of supply chain events as well as the transparent representation of a digital shadow throughout the entire supply chain.
The proper selection of a demand forecasting method is directly linked to the success of supply chain management (SCM). However, today’s manufacturing companies are confronted with uncertain and dynamic markets. Consequently, classical statistical methods are not always appropriate for accurate and reliable forecasting. Algorithms of Artificial intelligence (AI) are currently used to improve statistical methods. Existing literature only gives a very general overview of the AI methods used in combination with demand forecasting. This paper provides an analysis of the AI methods published in the last five years (2017-2021). Furthermore, a classification is presented by clustering the AI methods in order to define the trend of the methods applied. Finally, a classification of the different AI methods according to the dimensionality of data, volume of data, and time horizon of the forecast is presented. The goal is to support the selection of the appropriate AI method to optimize demand forecasting.
Artificial intelligence is a field of research that is seen as a means of realization regarding digitalization and industry 4.0. It is considered as the critical technology needed to drive the future evolution of manufacturing systems. At the same time, autonomous guided vehicles (AGV) developed as an essential part due to the flexibility they contribute to the whole manufacturing process within manufacturing systems. However, there are still open challenges in the intelligent control of these vehicles on the factory floor. Especially when considering dynamic environments where resources should be controlled in such a way, that they can be adjusted to turbulences efficiently. Therefore, this paper aimed to develop a conceptual framework for addressing a catalog of criteria that considers several machine learning algorithms to find the optimal algorithm for the intelligent control of AGVs. By applying the developed framework, an algorithm is automatically selected that is most suitable for the current operation of the AGV in order to enable efficient control within the factory environment. In future work, this decision-making framework can be transferred to even more scenarios with multiple AGV systems, including internal communication along with AGV fleets. With this study, the automatic selection of the optimal machine learning algorithm for the AGV improves the performance in such a way, that computational power is distributed within a hybrid system linking the AGV and cloud storage in an efficient manner.
The functionality of existing cyber-physical production systems generally focuses on mapping technologic specifications derived from production requirements. Consequently, such systems base their conception on a structurally mechanistic paradigm. Insofar as these approaches have considered humans, their conception likewise is based on the structurally identical paradigm. Due to the fundamental reorientation towards explicitly human-centered approaches, the fact that essential aspects of the dimension "human" remain unconsidered by the previous paradigm becomes more and more apparent. To overcome such limitations, mapping the "social" dimension requires a structurally different approach. In this paper, an anthropocentric approach is developed based on possible conceptions of the human being, enabling a structural integration of the human being in an extended dimension. Through the model, extending concepts for better integration of the human being in the sense of human-centered approaches, as envisioned in the Industrie 5.0 conception, is possible.
The paradigmatic shift of production systems towards Cyber-Physical Production Systems (CPPSs) requires the development of flexible and decentralized approaches. In this way, such systems enable manufacturers to respond quickly and accurately to changing requirements. However, domain-specific applications require the use of suitable conceptualizations. The issue at hand, when using various conceptualizations is the interoperability of different ontologies. To achieve flexibility and adaptability in CPPSs though requires overcoming interoperability issues within CPPSs. This paper presents an approach to increase flexibility and adaptability in CPPSs while addressing the interoperability issue. In this work, OWL ontologies conceptualize domain knowledge. The Intelligent Manufacturing Knowledge Ontology Repository (IMKOR) connects the domain knowledge in different ontologies. Testing if adaptions in one ontology within the IMKOR provide knowledge to the whole IMKOR. The tests showed, positive results and the repository makes the knowledge available to the whole CPPS. Furthermore, an increase in flexibility and adaptability was noticed.
Adoption of artificial intelligence (AI) has risen sharply in recent years but many firms are not successful in realising the expected benefits or even terminate projects before completion. While there are a number of previous studies that highlight challenges in AI projects, critical factors that lead to project failure are mostly unknown. The aim of this study is therefore to identify distinct factors that are critical for failure of AI projects. To address this, interviews with experts in the field of AI from different industries are conducted and the results are analyzed using qualitative analysis methods. The results show that both, organizational and technological issues can cause project failure. Our study contributes to knowledge by reviewing previously identified challenges in terms of their criticality for project failure based on new empirical data, as well as, by identifying previously unknown factors.
A closed-loop control for a cooperative innovation culture in interorganizational R&D projects
(2022)
Since project managers only have a limited authority in interorganizational R&D projects a cooperative innovation culture is essential for team cohesion and thus for achieving project scope in time and cost. For its development different factors depending on underlying values are essential. These factors must be learned iteratively by the project members so that they are living the values of a cooperative innovation culture. Hence, this paper raises the following research question: “How to control living the values of a cooperative innovation culture in interorganizational R&D projects?” To answer this question, a closed-loop control for a cooperative innovation culture is developed. The developed closed-loop control system includes several different functional units which show essential roles and several different variables which show what to consider and design in the control system. In addition, the developed closed-loop control system is generalized for other types of projects such as intraorganizational projects.
Allyls
(2022)
This chapter addresses the importance and usage of the commercially low-volume thermoset plastics group known as allyls. The three significant subelements of this group are poly(diallylphthalates), poly(diallylisophthalates), and poly(allyldiglycol carbonate). Chemistry, processing, and properties are also described. Allyl polymers are synthesized by radical polymerizations of allyl monomers that usually do not produce high-molecular-mass macromolecules. Therefore only a few specific monomers can produce thermosetting materials. Diallyldiglycolcarbonate (CR-39) and diallylphthalates are the most significant examples that have considerably improved our everyday life.
Unsaturated polyester resins (UPR) and vinyl ester resins (VER) are among the most commercially important thermosetting matrix materials for composites. Although comparatively low cost, their technological performance is suitable for a wide range of applications, such as fiber-reinforced plastics, artificial marble or onyx, polymer concrete, or gel coats. The main areas of UPR consumption include the wind energy, marine, pipe and tank, transportation, and construction industries.
This chapter discusses basic UPR and VER chemistry and technology of manufacturing, and consequent applications. Some important properties and performance characteristics are discussed, such as shrinkage behavior, flame retardance, and property modification by nanoparticles. Also briefly introduced and described are the practical aspects of UPR and VER processing, with special emphasis on the most widely used technological approaches, such as hand and spray layup, resin infusion, resin transfer molding, sheet and bulk molding, pultrusion, winding, and centrifugal casting.
Cross-linked thermoplastics
(2022)
Cross-linked thermoplastics represent an important class of materials for numerous applications such as heat-shrinkable tubing, rotational molded parts, and polyolefin foams. By cross-linking olefins, their mechanical performance can be significantly enhanced. This chapter covers the three main methods for the cross-linking of thermoplastics: radiation cross-linking, chemical cross-linking with organic peroxides, and cross-linking using silane-grafting agents. It also considers the major effects of the cross-linking procedure on the performance of the thermoplastic materials discussed.
Silicones
(2022)
Silicones are found in a variety of applications with requirements that range from long life at elevated temperatures to fluidity at low temperatures. This chapter first considers silicone elastomers and their application in room temperature vulcanizing (RTV) and heat curing systems (HTV). Also, new technologies for UV curing are introduced. Coverage of RTVs includes both one-component and two-component systems and the different cure chemistries of each and is followed by a separate discussion of silicone laminates. Due to the high importance of silicone fluids, they are also discussed. Fluids include polishes, release agents, surfactants, and dielectric fluids.
Cyanate ester resins
(2022)
Cyanate ester resins are an important class of thermosetting compounds that experience an ever-increasing interest as matrix systems for advanced polymer composite materials, which among other application fields are especially suitable for highly demanding applications in the aerospace or microelectronics industries. Other names for cyanate ester resins are cyanate resins, cyanic esters, or triazine resins. The various types of cyanate ester monomers share the –OCN functional group that trimerizes in the course of resin formation to yield a highly branched heterocyclic polymeric network based on the substituted triazine core structure.
Process analysis and process control have attracted increasing interest in recent years. The development and application of process analytical methods are a prerequisite for the knowledge-based manufacturing of industrial goods and allow for the production of high-value products of defined, constantly good quality. Discussed in this chapter are the measurement principle and some relevant aspects and illustrative examples of online monitoring tools as the basis for process control in the manufacturing and processing of thermosetting resins. Optical spectroscopy is featured as one of the main process analytical methods applicable to, among other applications, online monitoring of resin synthesis. In combination with chemometric methods for multivariate data analysis, powerful process models can be generated within the framework of feedback and feed-forward control concepts. Other analytical methods covered in this chapter are those frequently used to control further processing of thermosets to the final parts, including dielectric analysis, ultrasonics, fiber optics, and Fiber Bragg Grating sensors.
Self-healing thermosets
(2022)
This chapter discusses the basic extrinsic, intrinsic, and combined extrinsic/intrinsic strategies for equipping thermosetting polymers with self-healing properties. The main focus will be on the presentation of a holistic optimization of thermosetting materials, that is, on a simultaneous optimization of both self-healing and other, specialized material properties. Due to their very rigid, highly cross-linked three-dimensional structure, thermosetting polymers require special chemical strategies to achieve self-healing properties. The main chemical strategies available for this will be briefly outlined. The examples given illustrate interesting and/or typical procedures and serve as an inspiration to find solutions for your own applications. They summarize important recent development in research and technology aiming toward multifunctional truly smart self-healing thermosetting materials. An important aspect in this topic area is also how precisely the self-healing effects are analytically checked, quantified, and evaluated. A range of measuring methods is available for this purpose. In this chapter, the most important analytical tools for testing self-healing properties are briefly introduced and highlighted with some illustrative examples.
Today, many industrial tasks are not automated and still require human intervention. One of these tasks is the unloading of oversea containers. After the end of transportation to the sorting center, the containers must be unloaded manually for further sending the parcels to the recipients. A robot-based automatic unloading of containers was therefore researched. However, the promising results of the system developed in these projects could not be commercialized due to problems with its reliability. Mechanical, algorithmic or other limitations are possible causes of the observed errors. To analyze errors, it is necessary to evaluate the results of the robot’s work without complicating the existing system by adding new sensors to it. This paper presents a reference system based on machine learning to evaluate the robotics grasps of parcels. It analyzes two states of the container: before and after picking up one box. The states are represented as a point cloud received from a laser scanner. The proposed system evaluates the success of transferring a box from an overseas container to the sorting line by supervised learning using convolutional neural networks (CNN) and manual labeling of the data. The process of obtaining a working model using a hyperband model search with a maximum classification error of 3.9 % is also described.
Theory and practice of implementing a successful enterprise IoT strategy in the industry 4.0 era
(2021)
Since the arrival of the internet and affordable access to technologies, digital technologies have occupied a growing place in industries, propelling us towards a 4th industrial revolution: Industry 4.0. In today’s era of digital upheaval, enterprises are increasingly undergoing transformations that are leading to their digitalization. The traditional manufacturing industry is in the throes of a digital transformation that is accelerated by exponentially growing technologies (e.g., intelligent robots, Internet of Things, sensors, 3D printing). Around the world, enterprises are in a frantic race to implement solutions based on IoT to improve their productivity, innovation, and reduce costs and improve their markets on the international scene. Considering the immense transformative potential that IoTs and big data have to bring to the industrial sector, the adoption of IoT in all industrial systems is a challenge to remain competitive and thus transform the industry into a smart factory. This paper presents the description of the innovation and digitalization process, following the Industry 4.0 paradigm to implement a successful enterprise IoT strategy.
Conventional production systems are evolving through cyber-physical systems and application-oriented approaches of AI, more and more into "smart" production systems, which are characterized among other things by a high level of communication and integration of the individual components. The exchange of information between the systems is usually only oriented towards the data content, where semantics is usually only implicitly considered. The adaptability required by external and internal influences requires the integration of new or the redesign of existing components. Through an open application-oriented ontology the information and communication exchange are extended by explicit semantic information. This enables a better integration of new and an easier reconfiguration of existing components. The developed ontology, the derived application and use of the semantic information will be evaluated by means of a practical use case.
Business opportunities for energy providers to utilize flexible industrial demand are platform-based, connecting small and medium-sized enterprises (SMEs) to a virtual power plant (VPP) in complex ecosystems. Unlike in other VPPs, the focus is on participation, data, and control sovereignty for the SMEs. An exemplary application for an existing cement mill demonstrates positive margins. Viable VPP business models for small and medium-sized utilities include the “orchestrator,” i.e., adding value by linking services of specialized providers, the “integrator,” i.e., incorporating internal and external processes and resources, as well as the “white label user,” i.e., using a turn-key VPP from an exclusive cooperation partner.
Maintenance is an increasingly complex and knowledge-intensive field. In order to address these challenges, assistance systems based on augmented, mixed, or virtual reality can be applied. Therefore, the objective of this paper is to present a framework that can be used to identify, select, and implement an assistance system based on reality technology in the maintenance environment. The development of the framework is based on a systematic literature review and subject matter expert interviews. The framework provides the best technological and economic solution in several steps. The validation of the framework is carried out through a case study.
This paper presents the concept of the system architecture of a flexible cyber-physical factory control system. The system allows the automation of process structures using cyber-physical fractal nodes. These nodes have a functional and independent form and can be clustered to larger structures. This makes it possible to equip the factory with a flexible, freely scalable, modular system. The description of this system architecture and the associated rules and conditions is outlined in the concept.
Increasing complexity in manufacturing processes poses new challenges for industrial maintenance. In addition, advanced machine monitoring and lifetime forecasting options expand the tools and maintenance strategies available. Today, maintenance strategy selection is performed sequentially usually based on prioritised machines and components. These selections are optimized locally for each machine isolated, not considering the context of other machines within the value-adding network. To overcome these challenges, this paper presents an approach for an integrated maintenance strategy selection in one-step by an integrated model considering possible machine failures and the context of other machines within the value-adding network in parallel.
Railway operators are being challenged by increasing complexity and safeguarding the availability of passenger rolling stock, bringing maintenance and especially emerging technologies into the focus. This paper presents a model for selection and implementation of Industry 4.0 technologies in rolling stock maintenance. The model consists of different stages and considers the main components of rolling stock, the related appropriate maintenance strategies and Industry 4.0 technologies considering the maturity level of the railway operators. Relevant criteria and main prerequisites of the technologies were identified. The model proposes relevant activities and was validated by industry experts.
The technologies of digital transformation, such as the Internet-of-Things (IoT), artificial intelligence or predictive maintenance enable significant efficiency gains in industry and are becoming increasingly important as a competitive factor. However, their successful implementation and creative, future application requires the broad acceptance and knowledge of non-IT-related groups, such as production management students, engineers or skilled workers, which is still lacking today. This paper presents a low-threshold training concept bringing IoT-technologies and applications into manufacturing related higher education and employee training. The concept addresses the relevant topics starting from IoT-basics to predictive maintenance using mobile low-cost hardware and infrastructure.
The maintenance of railway infrastructure remains a challenge. Data acquisition technologies have evolved because of Industry 4.0, expanding the capabilities of predictive maintenance. Despite the advances, the potential of these emerging technologies has not been fully realised. This paper presents a technology selection framework in support of railway infrastructure predictive maintenance, which is based on qualitative methods. It consists of three stages, including the mapping of the infrastructure characteristics with the identified technologies, the evaluation of the most appropriate technologies, and the sourcing thereof. This presents the collective decision support output of the framework.
Today's logistics systems are characterized by uncertainty and constantly changing requirements. Rising demand for customized products, short product life cycles and a large number of variants increases the complexity of these systems enormously. In particular, intralogistics material flow systems must be able to adapt to changing conditions at short notice, with little effort and at low cost. To fulfil these requirements, the material flow system needs to be flexible in three important parameters, namely layout, throughput and product. While the scope of the flexibility parameters is described in literature, the respective effects on an intralogistics material flow system and the influencing factors are mostly unknown. This paper describes how flexibility parameters of an intralogistics system can be determined using a multi-method simulation. The study was conducted in the learning factory “Werk150” on the campus of Reutlingen University with its different means of transport and processes and validated in terms of practical experiments.
The production environment experiences copious challenges, but likewise discovers many new potential opportunities. To meet the new requirements, caused by the developments towards mass-customization, human-robot-cooperation (HRC) was identified as a key piece of technology and is becoming more and more important. HRC combines the strengths of robots, such as reliability, endurance and repeatability, with the strengths of humans, for instance flexibility and decision-making skills. Notwithstanding the high potential of HRC applications, the technology has not achieved a breakthrough in production so far. Studies have shown that one of the biggest obstacles for implementing HRC is the allocation of tasks. Another key technology that offers various opportunities to improve the production environment is Artificial Intelligence (AI). Therefore, this paper describes an AI supported method to improve the work organization in HRC in regards to the task-allocation. The aim of this method is to build a dynamic, semi-autonomous group work environment which keeps not just employee motivation at a high level, but also the product quality due to a decreased failure rate. The AI helps to detect the perfect condition in which the employee delivers the best performance and also supports at identifying the time when the worker leaves this optimal state. As soon as the employee reaches this trigger event, the allocation of the tasks adapts based on the identified stress. This adaptation aims to return the employee to the state of the optimal performance. In order to realize such a dynamic allocation, this method describes the creation of a pool with various interaction scenarios, as well as the AI supported recognition of the defined trigger event.
Manufacturing companies are confronted with external (e.g. short-term change of product configuration by the customer) and internal (e.g. production process deviations) turbulences which are affecting the performance of production. Predefined, centrally controlled logistics processes are limiting the possibilities of production to initiate countermeasures to react in an optimized way to these turbulences. The autonomous control of intralogistics offers a great potential to cope with these turbulences by using the respective flexibility corridors of production systems and applying intelligent logistic objects with decentralized decision and process execution capabilities to maintain a target-optimized production. A method for AI-based storage-location- and material-handling-optimization to achieve performance-optimized intralogistics system through continuous monitoring of performance-relevant parameters and influencing factors by using AI (e.g. for pattern recognition) has been developed. To provide the basis to investigate and demonstrate the potentials of autonomously controlled intralogistics in connection with turbulences of production and in combination with AI, an intelligent warehouse involving an indoor localization system, smart bins, manual, semi-automated/collaborative and autonomous transport systems has been developed and implemented at Werk150, the factory on campus of ESB Business School (Reutlingen University). This scenario, which has been integrated into graduate training modules, allows the analysis and demonstration of different measures of intralogistics to cope with turbulences in production involving amongst others storage and material provision processes. The target fulfilment of the applied intralogistics measures to master arising turbulences is assessed based on the overall performance of production considering lead times and adherence to delivery dates. By applying artificial intelligence (AI) algorithms the intelligent logistical objects (smart bin, transport systems, etc.) as well as the entire logistics system should be enabled to improve their decision and process execution capabilities to master short-term turbulences in the production system autonomously.
Teaching at assembly workstations in production in SMEs (small and medium sized companies) often does not take place at all or only insufficiently. In addition to the lack of technical content, there are also aggravatingly incorrect movement sequences from an ergonomic point of view, which "untrained" people usually automatically acquire. An AI based approach is used to analyze a definite workflow for a specific assembly scope regarding the behavior of several employees. Based on these different behaviors, the AI gives feedback at which points in time, work steps and movement’s particularly dangerous incorrect postures occur. Motion capturing and digital human model simulation in combination with the results of the AI define the optimized workflow. Individual employees can be trained directly due to the fact that AI identifies their most serious incorrect postures and provide them with a direct analogy of their “wrong” posture and “easy on the joints posture”. With the assistance of various test persons, the AI can conduct a study in which the most frequently occurring incorrect postures can be identified. This could be realized in general or tailored to specific groups of people (e.g. "People over 1.90m tall must be particularly careful not to make the following mistake...). The approach will be tested and validated at the Werk150, the factory of the ESB Business School, on the campus of the Reutlingen University. The new gained knowledge will be used subsequently for training in SMEs.
Human bestrophin-1 (hBest1) is a transmembrane Ca2+- dependent anion channel, associated with the transport of Cl−, HCO3- ions, γ-aminobutiric acid (GABA), glutamate (Glu), and regulation of retinal homeostasis. Its mutant forms cause retinal degenerative diseases, defined as Bestrophinopathies. Using both physicochemical - surface pressure/mean molecular area (π/A) isotherms, hysteresis, compressibility moduli of hBest1/sphingomyelin (SM) monolayers, Brewster angle microscopy (BAM) studies, and biological approaches - detergent membrane fractionation, Laurdan (6-dodecanoyl-N,N-dimethyl-2-naphthylamine) and immunofluorescence staining of stably transfected MDCK-hBest1 and MDCK II cells, we report:
1) Ca2+, Glu and GABA interact with binary hBest1/SM monolayers at 35 °C, resulting in changes in hBest1 surface conformation, structure, self-organization and surface dynamics. The process of mixing in hBest1/SM monolayers is spontaneous and the effect of protein on binary films was defined as “fluidizing”, hindering the phase-transition of monolayer from liquid-expanded to intermediate (LE-M) state;
2) in stably transfected MDCK-hBest1 cells, bestrophin-1 was distributed between detergent resistant (DRM) and detergent-soluble membranes (DSM) - up to 30 % and 70 %, respectively; in alive cells, hBest1 was visualized in both liquid-ordered (Lo) and liquid-disordered (Ld) fractions, quantifying protein association up to 35 % and 65 % with Lo and Ld. Our results indicate that the spontaneous miscibility of hBest1 and SM is a prerequisite to diverse protein interactions with membrane domains, different structural conformations and biological functions.
Employing diffuse reflection ultraviolet visible (UV–Vis) spectroscopy we developed an approach that is capable to quantitatively determine flux residues on a technical copper surface. The technical copper surface was soldered with a no-clean flux system of organic acids. By a post-solder cleaning step with different cleaning parameters, various levels of residues were produced. The surface was quantitatively and qualitatively characterized using X-ray photoelectron spectroscopy (XPS), Auger electron spectroscopy (AES), Fourier transform infrared spectroscopy (FTIR) and diffuse reflection UV–Vis spectroscopy. With the use of a multivariate analysis (MVA) we examined the UV–Vis data to create a correlation to the carbon content on the surface. The UV–Vis data could be discriminated for all groups by their level of organic residues. Combined with XPS the data were evaluated by a partial least squares (PLS) regression to establish a model. Based on this predictive model, the carbon content was calculated with an absolute error of 2.7 at.%. Due to the high correlation of predictive model, the easy-to-use measurement and the evaluation by multivariate analysis the developed method seems suitable for an online monitoring system. With this system, flux residues can be detected in a manufacturing cleaning process of technical surfaces after soldering.
Respiratory diseases are leading causes of death and disability in the world. The recent COVID-19 pandemic is also affecting the respiratory system. Detecting and diagnosing respiratory diseases requires both medical professionals and the clinical environment. Most of the techniques used up to date were also invasive or expensive.
Some research groups are developing hardware devices and techniques to make possible a non-invasive or even remote respiratory sound acquisition. These sounds are then processed and analysed for clinical, scientific, or educational purposes.
We present the literature review of non-invasive sound acquisition devices and techniques.
The results are about a huge number of digital tools, like microphones, wearables, or Internet of Thing devices, that can be used in this scope.
Some interesting applications have been found. Some devices make easier the sound acquisition in a clinic environment, but others make possible daily monitoring outside that ambient. We aim to use some of these devices and include the non-invasive recorded respiratory sounds in a Digital Twin system for personalized health.
Normal breathing during sleep is essential for people’s health and well-being. Therefore, it is crucial to diagnose apnoea events at an early stage and apply appropriate therapy. Detection of sleep apnoea is a central goal of the system design described in this article. To develop a correctly functioning system, it is first necessary to define the requirements outlined in this manuscript clearly. Furthermore, the selection of appropriate technology for the measurement of respiration is of great importance. Therefore, after performing initial literature research, we have analysed in detail three different methods and made a selection of a proper one according to determined requirements. After considering all the advantages and disadvantages of the three approaches, we decided to use the impedance measurement-based one. As a next step, an initial conceptual design of the algorithm for detecting apnoea events was created. As a result, we developed an activity diagram on which the main system components and data flows are visually represented.
Preliminary results of homomorphic deconvolution application to surface EMG signals during walking
(2021)
Homomorphic deconvolution is applied to sEMG signals recorded during walking. Gastrocnemius lateralis and tibialis anterior signals were acquired according to SENIAM recommendation. MUAP parameters like amplitude and scale were estimated, whilst the MUAP shape parameter was fixed. This features a useful time-frequency representation of sEMG signal. Estimation of scale MUAP parameter was verified extracting the mean frequency of filtered EMG signal, extracted from the scale parameter estimated with two different MUAP shape values.
The present work proposes the use of modern ICT technologies such as smartphones, NFCs, internet, and web technologies, to help patients in carrying out their therapies. The implemented system provides a calendar with a reminder of the assumptions, ensures the drug identification through NFC, allows remote assistance from healthcare staff and family members to check and manage the therapy in real-time. The system also provides centralized information on the patient's therapeutic situation, helpful in choosing new compatible therapies.
This paper covers test and verification of a forecast-based Monte Carlo algorithm for an optimized, demand-oriented operation of combined heat and power (CHP) units using the hardware-in-the-loop approach. For this purpose, the optimization algorithm was implemented at a test bench at Reutlingen University for controlling a CHP unit in combination with a thermal energy storage, both in real hardware. In detail, the hardware-in-the-loop tests are intended to reveal the effects of demand forecasting accuracy, the impact of thermal energy storage capacity and the influence of load profiles on demand-oriented operation of CHP units. In addition, the paper focuses on the evaluation of the content of energy in the thermal energy storage under practical conditions. It is shown that a 5-layer model allows to determine the energy stored quite accurately, which is verified by experimental results. The hardware-in-the-loop tests disclose that demand forecasting accuracies, especially electricity demand forecasting, as well as load profiles strongly impact the potential for CHP electricity utilization on-site in demand-oriented mode. Moreover, it is shown that a larger effective capacity of the thermal energy storage positively affects demand-oriented operation. In the hardware-in-the-loop tests, the fraction of electricity generated by the CHP unit utilized on-site could thus be increased by a maximum of 27% compared to heat-led operation, which is still the most common modus operandi of small-scale CHP plants. Hence, the hardware-in-the-loop tests were adequate to prove the significant impact of the proposed algorithm for optimization of demand-oriented operation of CHP units.