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Despite the unstoppable global drive towards electric mobility, the electrification of sub-Saharan Africa’s ubiquitous informal multi-passenger minibus taxis raises substantial concerns. This is due to a constrained electricity system, both in terms of generation capacity and distribution networks. Without careful planning and mitigation, the additional load of charging hundreds of thousands of electric minibus taxis during peak demand times could prove catastrophic. This paper assesses the impact of charging 202 of these taxis in Johannesburg, South Africa. The potential of using external stationary battery storage and solar PV generation is assessed to reduce both peak grid demand and total energy drawn from the grid. With the addition of stationary battery storage of an equivalent of 60 kWh/taxi and a solar plant of an equivalent of 9.45 kWpk/taxi, the grid load impact is reduced by 66%, from 12 kW/taxi to 4 kW/taxi, and the daily grid energy by 58% from 87 kWh/taxi to 47 kWh/taxi. The country’s dependence on coal to generate electricity, including the solar PV supply, also reduces greenhouse gas emissions by 58%.
Menopause is the permanent cessation of menstruation occurring naturally in women's aging. The most frequent symptoms associated with menopausal phases are mucosal dryness, increased weight and body fat, and changes in sleep patterns. Oral symptoms in menopause derived from saliva flow reduction can lead to dry mouth, ulcers, and alterations of taste and swallowing patterns. However, the oral health phenotype of postmenopausal women has not been characterized. The aim of the study was to determine postmenopausal women's oral phenotype, including medical history, lifestyle, and oral assessment through artificial intelligence algorithms. We enrolled 100 postmenopausal women attending the Dental School of the University of Seville were included in the study. We collected an extensive questionnaire, including lifestyle, medication, and medical history. We used an unsupervised k-means algorithm to cluster the data following standard features for data analysis. Our results showed the main oral symptoms in our postmenopausal cohort were reduced salivary flow and periodontal disease. Relying on the classical assessment of the collected data, we might have a biased evaluation of postmenopausal women. Then, we used artificial intelligence analysis to evaluate our data obtaining the main features and providing a reduced feature defining the oral health phenotype. We found 6 clusters with similar features, including medication affecting salivation or smoking as essential features to obtain different phenotypes. Thus, we could obtain main features considering differential oral health phenotypes of postmenopausal women with an integrative approach providing new tools to assess the women in the dental clinic.
Rare but extreme events, such as pandemics, terror attacks, and stock market collapses, pose a risk that could undermine cooperation in societies and groups. We extend the public goods game (PGG) to investigate the relationship between rare but extreme external risks and cooperation in a laboratory experiment. By incorporating risk as an external random variable in the PGG, independent of the participants’ contributions, we preserve the economic equilibrium of non-cooperation in the original game. Furthermore, we examine whether cooperation can be restored by the relatively simple intervention of informing about countermeasures while keeping the actual risk constant. Our experimental results reveal that on average extreme risks indeed decrease contributions by about 20%; however, countermeasure information increases contributions by about 10%. Specifically, in the first interactions, cooperation levels can even reach those observed in the riskless baseline. Our results suggest that countermeasure information could help reinforce social cohesion and resilience in the face of rare but extreme risks.
The introduction of smart contracts has expanded the applicability of blockchains to many domains beyond finance and cryptocurrencies. Moreover, different blockchain technologies have evolved that target special requirements. As a result, in practice, often a combination of different blockchain systems is required to achieve an overall goal. However, due to the heterogeneity of blockchain protocols, the execution of distributed business transactions that span several blockchains leads to multiple interoperability and integration challenges. Therefore, in this article, we examine the domain of Cross-Chain Smart Contract Invocations (CCSCIs), which are distributed transactions that involve the invocation of smart contracts hosted on two or more blockchain systems. We conduct a systematic multi-vocal literature review to get an overview of the available CCSCI approaches. We select 20 formal literature studies and 13 high-quality gray literature studies, extract data from them, and analyze it to derive the CCSCI Classification Framework. With the help of the framework, we group the approaches into two categories and eight subcategories. The approaches differ in multiple characteristics, e.g., the mechanisms they follow, and the capabilities and transaction processing semantics they offer. Our analysis indicates that all approaches suffer from obstacles that complicate real-world adoption, such as the low support for handling heterogeneity and the need for trusted third parties.
In this paper, the essential sponsorship basics are presented and the communication instrument of sports sponsorship is illustrated. Building on this, both the perspectives of sponsors and sponsees are examined in detail. In addition, the special features of sports event sponsorships are highlighted. Finally, current developments in sports sponsorship in the context of the FIFA Soccer World Cup 2022 in Qatar and the UEFA European Soccer Championship 2024 in Germany are compared and discussed.
Wave-like differential equations occur in many engineering applications. Here the engineering setup is embedded into the framework of functional analysis of modern mathematical physics. After an overview, the –Hilbert space approach to free Euler–Bernoulli bending vibrations of a beam in one spatial dimension is investigated. We analyze in detail the corresponding positive, selfadjoint differential operators of 4-th order associated to the boundary conditions in statics. A comparison with free string wave swinging is outlined.
Das Thema des Direktvertriebs (Direct-to-Customer oder kurz D-to-C) in der Automobilindustrie ist en vogue, denn nach Valtech (2023, S. 2) ist die Umstellung der Vertriebsmodelle in dieser Branche unumgänglich. Die Covid-19-Pandemie hat zudem noch als Katalysator für den D-to-C fungiert und die digitale Transformation sowie die Akzeptanz virtueller Verkaufsprozesse beschleunigt.
This paper explores the application of People Analytics in
recruiting professors for universities of applied sciences. Using data-driven personas, the research project aims to identify and communicate the different paths and connections leading candidates to a professorship. The authors introduce the concept of personas, describe the underlying data source and derive an example for the current project.
Comparative analysis of the chemical and rheological curing kinetics of formaldehyde-based wood adhesives is crucial for assessing their respective performance. Differential scanning calorimetry (DSC) and rheometry are the conventional techniques used for monitoring the curing processes leading to crosslinking polymerization of the adhesives. However, the direct comparison of these techniques is inappropriate due to the intrinsic differences in their underlying procedures. To address this challenge, the two adhesive samples were sequentially cured, firstly with rheometry and followed by DSC. The observed higher curing degree in the subsequent DSC procedure underpins the incomplete curing of the samples during initial rheometry. Furthermore, the comparative assessment of the activation energies, molar ratios, and active groups of the two adhesives highlights the importance of the pre-exponential factor in addition to the activation energies, as it attributes to the probability of active groups coinciding at the appropriate spatial arrangement.
Tech hubs (THs) and cognate structures are nowadays ubiquitous in the innovation ecosystem of Sub-Saharan African (SSA) countries. However, the concept of THs is fuzzy due to the lack of a clear and universally accepted definition. This ambiguity is further compounded by the diverse range of organizations that self-identify as hubs, or are categorized as such by others. As a result, research on THs in SSA remained limited. Against the backdrop of established research on the interconnectedness of technology, innovation and entrepreneurship in different organizational forms, this paper is meant to provide fresh insights into the study of THs in SSA. To advance future research, first, it reveals what is special about THs in SSA and how they are related to existing concepts. I particularly argue that they contour a fourth-wave model of incubation. Second, four main categories are unfolded to delineate THs in SSA which is the cornerstone for future research.
Salivary gland tumors (SGTs) are a relevant, highly diverse subgroup of head and neck tumors whose entity determination can be difficult. Confocal Raman imaging in combination with multivariate data analysis may possibly support their correct classification. For the analysis of the translational potential of Raman imaging in SGT determination, a multi-stage evaluation process is necessary. By measuring a sample set of Warthin tumor, pleomorphic adenoma and non-tumor salivary gland tissue, Raman data were obtained and a thorough Raman band analysis was performed. This evaluation revealed highly overlapping Raman patterns with only minor spectral differences. Consequently, a principal component analysis (PCA) was calculated and further combined with a discriminant analysis (DA) to enable the best possible distinction. The PCA-DA model was characterized by accuracy, sensitivity, selectivity and precision values above 90% and validated by predicting model-unknown Raman spectra, of which 93% were classified correctly. Thus, we state our PCA-DA to be suitable for parotid tumor and non-salivary salivary gland tissue discrimination and prediction. For evaluation of the translational potential, further validation steps are necessary.
Im Team zum fliegenden Traum
(2024)
Purpose
As a response to the increased frequency of disruptive events and intense competition, organizational agility has become a key concept in organizational research. Fostering organizational agility requires leveraging knowledge that exists both outside (exploration) and inside (exploitation) the organization. This research tests the so-called ambidexterity hypothesis, which claims that a balance between exploration and exploitation leads to increased organizational outcomes, including the development of organizational agility. Complementing previously established measurement models on ambidexterity, this research proposes an alternative measurement model to analyze how ambidexterity can enhance organizational agility and, indirectly, performance, taking into consideration the moderating effect of environmental competitiveness.
Design/methodology/approach
A review of existing measurement models for ambidexterity shows that tension, a crucial aspect of ambidexterity, is often neglected. The authors, therefore, develop a new measurement model of ambidexterity to incorporate ambidexterity-induced tension. Using this measurement model, they examine the effect of ambidexterity on the development of entrepreneurial and adaptive agility as well as performance.
Findings
Ambidexterity positively influences both entrepreneurial and adaptive agility, indicating that a balance between exploration and exploitation has superior organizational effects. This finding confirms the ambidexterity hypothesis with respect to organizational agility. Furthermore, both entrepreneurial and adaptive agility drive organizational performance. These two indirect effects via agility fully mediate the impact of ambidexterity on organizational performance. Finally, environmental competitiveness positively moderates the relationship between ambidexterity and adaptive agility.
Originality/value
The findings extend research on ambidexterity by showing its positive effects on organizational agility. Furthermore, the study proposes an alternative operationalization to capture the ambidexterity construct that may lay the groundwork for further applications of the ambidexterity concept.
Software scripts for sensor data extraction in Rasberry Pi: user-space and kernel-space comparison
(2024)
This paper compares two popular scripting implementations for hardware prototyping: Python scripts execut from User-Space and C-based Linux-Driver processes executed from Kernel-Space, which can provide information to researchers when considering one or another in their implementations. Conclusions exhibit that deploying software scripts in the kernel space makes it possible to grant a certain quality of sensor information using a Raspberry Pi without the need for advanced real-time operational systems.
Accurate monitoring of a patient's heart rate is a key element in the medical observation and health monitoring. In particular, its importance extends to the identification of sleep-related disorders. Various methods have been established that involve sensor-based recording of physiological signals followed by automated examination and analysis. This study attempts to evaluate the efficacy of a non-invasive HR monitoring framework based on an accelerometer sensor specifically during sleep. To achieve this goal, the motion induced by thoracic movements during cardiac contractions is captured by a device installed under the mattress. Signal filtering techniques and heart rate estimation using the symlets6 wavelet are part of the implemented computational framework described in this article. Subsequent analysis indicates the potential applicability of this system in the prognostic domain, with an average error margin of approximately 3 beats per minute. The results obtained represent a promising advancement in non-invasive heart rate monitoring during sleep, with potential implications for improved diagnosis and management of cardiovascular and sleep-related disorders.
The massive use of patient data for the training of artificial intelligence algorithms is common nowadays in medicine. In this scientific work, a statistical analysis of one of the most used datasets for the training of artificial intelligence models for the detection of sleep disorders is performed: sleep health heart study 2. This study focuses on determining whether the gender and age of the patients have a relevant influence to consider working with differentiated datasets based on these variables for the training of artificial intelligence models.
Human pose estimation (HPE) is integral to scene understanding in numerous safety-critical domains involving human-machine interaction, such as autonomous driving or semi-automated work environments. Avoiding costly mistakes is synonymous with anticipating failure in model predictions, which necessitates meta-judgments on the accuracy of the applied models. Here, we propose a straightforward human pose regression framework to examine the behavior of two established methods for simultaneous aleatoric and epistemic uncertainty estimation: maximum a-posteriori (MAP) estimation with Monte-Carlo variational inference and deep evidential regression (DER). First, we evaluate both approaches on the quality of their predicted variances and whether these truly capture the expected model error. The initial assessment indicates that both methods exhibit the overconfidence issue common in deep probabilistic models. This observation motivates our implementation of an additional recalibration step to extract reliable confidence intervals. We then take a closer look at deep evidential regression, which, to our knowledge, is applied comprehensively for the first time to the HPE problem. Experimental results indicate that DER behaves as expected in challenging and adverse conditions commonly occurring in HPE and that the predicted uncertainties match their purported aleatoric and epistemic sources. Notably, DER achieves smooth uncertainty estimates without the need for a costly sampling step, making it an attractive candidate for uncertainty estimation on resource-limited platforms.
Sie sind es leid, Ihre wertvolle Arbeitszeit in endlosen Meetings zu verschwenden? Sie sind enttäuscht darüber, wie selten Meetingziele vollständig erreicht werden? Und es ist Ihnen bewusst, welche immensen Kosten Meetings verursachen?
Erleben Sie die Reise von Verkaufsleiter Frank, der sich mit seinem Team dem Meeting-Dilemma stellt und gemeinsam den größten Zeitfresser der Arbeitswelt besiegt. Begleiten Sie dieses innovative Unternehmen mit seinen Menschen und Charakteren, die auf ihrem Web zu einer optimierten Meetingkultur zahlreiche Herausforderungen meistern. Lassen Sie sich davon mitreißen und anregen, Ihren eigenen persönlichen Weg in Ihrer Praxis zu finden, so dass Ihre Meetings zum Motor für produktive Zusammenarbeit in Ihrer Organisation werden.
Automatic content creation system for augmented reality maintenance applications for legacy machines
(2024)
Augmented reality (AR) applications have great potential to assist maintenance workers in their operations. However, creating AR solutions is time-consuming and laborious, which limits its widespread adoption in the industry. It therefore often happens that even with the latest generation machines, instead of an AR solution, the user only receives an electronic manual for the equipment operation and maintenance. This is commonplace with legacy machines. For this reason, solutions are required that simplify the creation of such AR solutions. This paper presents an approach using an electronic manual as a basis to create fast and cost-effective AR solutions for maintenance. As part of the approach, an application was developed to automatically identify and subdivide the chapters of electronic manuals via the bookmarks in the table of contents. The contents are then automatically uploaded to a central server and indexed with a suitable marker to make the data retrievable. The prepared content can then be accessed for creating context-related AR instructions via the marker. The application is characterized by the fact that no developers or experts are required to prepare the information. In addition to complying with common design criteria, the clear presentation of the contents and the intuitive use of the system offer added value for the performance of maintenance tasks. Together, these two elements form a novel way to retrofit legacy machines with AR maintenance instructions. The practical validation of the system took place in a factory environment. For this purpose, the content was created for a filter change on a CNC milling machine. The results show that inexperienced users can extract appropriate content with the software application. Furthermore, it is shown that maintenance workers, can access the content with an AR application developed for the Microsoft HoloLens 2 and complete simple tasks provided in the manufacturer's electronic manual.
Evaluation of a contactless accelerometer sensor system for heart rate monitoring during sleep
(2024)
The monitoring of a patient's heart rate (HR) is critical in the diagnosis of diseases. In the detection of sleep disorders, it also plays an important role. Several techniques have been proposed, including using sensors to record physiological signals that are automatically examined and analysed. This work aims to evaluate using a contactless HR monitoring system based on an accelerometer sensor during sleep. For this purpose, the oscillations caused by chest movements during heart contractions are recorded by an installation mounted under the bed mattress. The processing algorithm presented in this paper filters the signals and determines the HR. As a result, an average error of about 5 bpm has been documented, i.e., the system can be considered to be used for the forecasted domain.
Based on social information processing theory, this research examines whether and how an employee’s proactive personality influences intrinsic and extrinsic career growth. It also examines the mediating effects of two types of proactive behaviors (voice behavior and taking charge) and the moderating effect of a leader’s proactive personality. A sample of 307 employee-leader dyads participated in this survey. Structural equation modeling was used to test the hypotheses, and the bootstrap procedure was used to test the indirect effects. Results show that an employee’s proactive personality has significant positive effects on both intrinsic and extrinsic career growth. The mediating effect of taking charge was confirmed, while the mediating effect of voice behavior was not. Leader proactive personality weakens the relationship between employee proactive personality and the two types of proactive behaviors. Employee proactive personality is more positively related to intrinsic and extrinsic career growth via proactive behaviors when a leader’s proactive personality is low. This study extends the literature on proactive personality, proactive behavior, and career development by examining the underlying determination, mediation, and moderation mechanisms.
The article pleads for Education for Sustainable Development (ESD) in the textile and fashion sector and shows possibilities how this can be implemented from elementary school to higher education and vocational training. It begins by highlighting the non-sustainable practices and deficits that can be found in the fashion and textile sector worldwide and explains the sustainability goals in the context of the UN Roadmap ESD for 2030. In order to raise the awareness for sustainability and implement these goals, education is needed. The article introduces the concept of ESD as a guiding principle with the core element design competence, implemented by the interdisciplinary method of Design Thinking (DT). In order to successfully teach the ESD-relevant design competence, various didactic principles are required. It can be shown that they are very similar to the principles and phases of DT. Within a research project DT and its potential for implementing ESD has been investigated in teaching-learning situations at elementary schools as well as in an interdisciplinary seminar for student teachers. These findings have been transferred to the EU project Fashion DIET, which pursues the goal of implementing ESD in the textile and fashion sector. By means of an online pilot workshop, the methods and principles of DT were presented and explained to lecturers, teachers and educators, who gave their feedback on the potential of DT as a method to implement ESD as a guiding principle in their curricula.
Student-faculty interactions that promote learning are essential contributors to student retention, academic success and satisfaction. But the factors that causally initiate and frame these interactions are not well understood. Only if students evaluate these interactions as positive will they seek them. We conducted a survey experiment with students (n = 375) from a tuition-fee-free German business school, using conditional process analysis to assess which factors frame effective interactions. We focus on out-of-classroom standard and non-standard requests that students make to faculty, then investigate how faculty and student gender and students’ academic entitlement influence the interaction. Our study examines how students evaluate the interaction with faculty: when they seek interaction, their expectations of getting their requests approved, and their disappointment when their requests are declined. We find a significant influence of the request type along with moderating effects of faculty gender, student gender and student entitlement, particularly for non-standard work requests. We conclude with policy implications for university management: developing target-group-specific measures that facilitate the desired and positively evaluated student-faculty interactions might benefit all university stakeholders.
For optimization of production processes and product quality, often knowledge of the factors influencing the process outcome is compulsory. Thus, process analytical technology (PAT) that allows deeper insight into the process and results in a mathematical description of the process behavior as a simple function based on the most important process factors can help to achieve higher production efficiency and quality. The present study aims at characterizing a well-known industrial process, the transesterification reaction of rapeseed oil with methanol to produce fatty acid methyl esters (FAME) for usage as biodiesel in a continuous micro reactor set-up. To this end, a design of experiment approach is applied, where the effects of two process factors, the molar ratio and the total flow rate of the reactants, are investigated. The optimized process target response is the FAME mass fraction in the purified nonpolar phase of the product as a measure of reaction yield. The quantification is performed using attenuated total reflection infrared spectroscopy in combination with partial least squares regression. The data retrieved during the conduction of the DoE experimental plan were used for statistical analysis. A non-linear model indicating a synergistic interaction between the studied factors describes the reactor behavior with a high coefficient of determination (R²) of 0.9608. Thus, we applied a PAT approach to generate further insight into this established industrial process.
„Tue Gutes und rede darüber“ lautet eine leicht verständliche Ur-Definition von Öffentlichkeitsarbeit, die längst zu einem Sprichwort geworden ist. Im Laufe der Zeit kamen auf die Public Relations zahlreiche Veränderungen zu: Die Sozialen Medien bewirkten, dass der interaktive Dialog und das Zuhören in den Fokus der PR rückten: „Tue Gutes und lasse andere darüber reden“ war die hierzu passende Aktualisierung. Einer der jüngsten Trends in der PR ist die Nachhaltigkeitskommunikation, die sogenannte „Green PR“, das heißt die Umsetzung glaubwürdiger, nachhaltiger Kommunikationsstrategien. Damit erfährt das Sprichwort ein weiteres Update zu „Tue nachhaltig Gutes und lasse andere dabei mitreden.“
This article provides a stochastic agent-based model to exhibit the role of aggregation metrics in order to mitigate polarization in a complex society. Our sociophysics model is based on interacting and nonlinear Brownian agents, which allow us to study the emergence of collective opinions. The opinion of an agent, x i (t) is a continuous positive value in an interval [0, 1]. We find (i) most agent-metrics display similar outcomes. (ii) The middle-metric and noisy-metric obtain new opinion dynamics either towards assimilation or fragmentation. (iii) We show that a developed 2-stage metric provide new insights about convergence and equilibria. In summary, our simulation demonstrates the power of institutions, which affect the emergence of collective behavior. Consequently, opinion formation in a decentralized complex society is reliant to the individual information processing and rules of collective behavior.
Intracranial brain tumors are one of the ten most common malignant cancers and account for substantial morbidity and mortality. The largest histological category of primary brain tumors is the gliomas which occur with an ultimate heterogeneous appearance and can be challenging to discern radiologically from other brain lesions. Neurosurgery is mostly the standard of care for newly diagnosed glioma patients and may be followed by radiation therapy and adjuvant temozolomide chemotherapy.
However, brain tumor surgery faces fundamental challenges in achieving maximal tumor removal while avoiding postoperative neurologic deficits. Two of these neurosurgical challenges are presented as follows. First, manual glioma delineation, including its sub-regions, is considered difficult due to its infiltrative nature and the presence of heterogeneous contrast enhancement. Second, the brain deforms its shape, called “brain shift,” in response to surgical manipulation, swelling due to osmotic drugs, and anesthesia, which limits the utility of pre-operative imaging data for guiding the surgery.
Image-guided systems provide physicians with invaluable insight into anatomical or pathological targets based on modern imaging modalities such as magnetic resonance imaging (MRI) and Ultrasound (US). The image-guided toolkits are mainly computer-based systems, employing computer vision methods to facilitate the performance of peri-operative surgical procedures. However, surgeons still need to mentally fuse the surgical plan from pre-operative images with real-time information while manipulating the surgical instruments inside the body and monitoring target delivery. Hence, the need for image guidance during neurosurgical procedures has always been a significant concern for physicians.
This research aims to develop a novel peri-operative image-guided neurosurgery (IGN) system, namely DeepIGN, that can achieve the expected outcomes of brain tumor surgery, thus maximizing the overall survival rate and minimizing post-operative neurologic morbidity. In the scope of this thesis, novel methods are first proposed for the core parts of the DeepIGN system of brain tumor segmentation in MRI and multimodal pre-operative MRI to the intra-operative US (iUS) image registration using the recent developments in deep learning. Then, the output prediction of the employed deep learning networks is further interpreted and examined by providing human-understandable explainable maps. Finally, open-source packages have been developed and integrated into widely endorsed software, which is responsible for integrating information from tracking systems, image visualization, image fusion, and displaying real-time updates of the instruments relative to the patient domain.
The components of DeepIGN have been validated in the laboratory and evaluated in the simulated operating room. For the segmentation module, DeepSeg, a generic decoupled deep learning framework for automatic glioma delineation in brain MRI, achieved an accuracy of 0.84 in terms of the dice coefficient for the gross tumor volume. Performance improvements were observed when employing advancements in deep learning approaches such as 3D convolutions over all slices, region-based training, on-the-fly data augmentation techniques, and ensemble methods.
To compensate for brain shift, an automated, fast, and accurate deformable approach, iRegNet, is proposed for registering pre-operative MRI to iUS volumes as part of the multimodal registration module. Extensive experiments have been conducted on two multi-location databases: the BITE and the RESECT. Two expert neurosurgeons conducted additional qualitative validation of this study through overlaying MRI-iUS pairs before and after the deformable registration. Experimental findings show that the proposed iRegNet is fast and achieves state-of-the-art accuracies. Furthermore, the proposed iRegNet can deliver competitive results, even in the case of non-trained images, as proof of its generality and can therefore be valuable in intra-operative neurosurgical guidance.
For the explainability module, the NeuroXAI framework is proposed to increase the trust of medical experts in applying AI techniques and deep neural networks. The NeuroXAI includes seven explanation methods providing visualization maps to help make deep learning models transparent. Experimental findings showed that the proposed XAI framework achieves good performance in extracting both local and global contexts in addition to generating explainable saliency maps to help understand the prediction of the deep network. Further, visualization maps are obtained to realize the flow of information in the internal layers of the encoder-decoder network and understand the contribution of MRI modalities in the final prediction. The explainability process could provide medical professionals with additional information about tumor segmentation results and therefore aid in understanding how the deep learning model is capable of processing MRI data successfully.
Furthermore, an interactive neurosurgical display has been developed for interventional guidance, which supports the available commercial hardware such as iUS navigation devices and instrument tracking systems. The clinical environment and technical requirements of the integrated multi-modality DeepIGN system were established with the ability to incorporate: (1) pre-operative MRI data and associated 3D volume reconstructions, (2) real-time iUS data, and (3) positional instrument tracking. This system's accuracy was tested using a custom agar phantom model, and its use in a pre-clinical operating room is simulated. The results of the clinical simulation confirmed that system assembly was straightforward, achievable in a clinically acceptable time of 15 min, and performed with a clinically acceptable level of accuracy.
In this thesis, a multimodality IGN system has been developed using the recent advances in deep learning to accurately guide neurosurgeons, incorporating pre- and intra-operative patient image data and interventional devices into the surgical procedure. DeepIGN is developed as open-source research software to accelerate research in the field, enable ease of sharing between multiple research groups, and continuous developments by the community. The experimental results hold great promise for applying deep learning models to assist interventional procedures - a crucial step towards improving the surgical treatment of brain tumors and the corresponding long-term post-operative outcomes.
How mechanical and physicochemical material characteristics influence adipose-derived stem cell fate
(2023)
Adipose-derived stem cells (ASCs) are a subpopulation of mesenchymal stem cells. Compared to bone marrow-derived stem cells, they can be harvested with minimal invasiveness. ASCs can be easily expanded and were shown to be able to differentiate into several clinically relevant cell types. Therefore, this cell type represents a promising component in various tissue engineering and medical approaches (e.g., cell therapy). In vivo cells are surrounded by the extracellular matrix (ECM) that provides a wide range of tissue-specific physical and chemical cues, such as stiffness, topography, and chemical composition. Cells can sense the characteristics of their ECM and respond to them in a specific cellular behavior (e.g., proliferation or differentiation). Thus, in vitro biomaterial properties represent an important tool to control ASCs behavior. In this review, we give an overview of the current research in the mechanosensing of ASCs and current studies investigating the impact of material stiffens, topography, and chemical modification on ASC behavior. Additionally, we outline the use of natural ECM as a biomaterial and its interaction with ASCs regarding cellular behavior.
In countries such as Germany, where municipalities have planning sovereignty, problems of urban sprawl often arise. As the dynamics of land development have not substantially subsided over the last years, the national government decided to test the instrument of ‘Tradable Planning Permits’ (TPP) in a nationwide field experiment with 87 municipalities involved. The field experiment was able to implement the key features of a TPP system in a laboratory setting with approximated real socioeconomic and planning conditions. In a TPP system allocated planning permits must be used by municipalities for developing land. The permits can be traded between local jurisdictions, so that they have flexibility in deciding how to comply with the regulation. In order to evaluate the performance of such a system, specific field data about future building areas and their impact on community budgets for the period 2014–2028 were collected. The field experiment contains several sessions with representatives of the municipalities and with students. The participants were confronted with two (municipalities) and four (students) schemes. The results show that a trading system can curb down land development in an effective and also efficient manner. However, depending on the regulatory framework, the trading schemes show different price developments and distributional effects. The unexperienced representatives of the local authorities can easily handle with the permits in the administration and in the established market. A trading scheme sets very high incentives to save open space and to direct development activities to areas within existing planning boundaries. It is therefore a promising instrument for Germany and also other regions or countries with an established land-use planning system.
At the beginning of 2022, Frontiers in Bioengineering and Biotechnology - Biomaterials Section has published a Research Topic on “Functional Surfaces and Biomaterials.” The aim of this Research Topic is to summarize the current state of research and development in the field of functional surfaces and biomaterials with a particular focus on biotechnological and medical applications.
The guest editorial team would like to thank all colleagues from around the world who submitted their reviews and research articles for the Research Topic. By the end of August 2022, we have successfully collected 20 articles by 138 participating authors following the peer review process. We also tried to select manuscripts from different research areas to cover the most relevant Research Topic of interest, from drug delivery systems to bone tissue engineering to biosensors and general aspects in biomedicine. By the end of December, the 20 articles had been viewed for more than 21000 times with downloads more than 4,000 times, and 11 articles have reached more than 1,000 views.
Titanium(IV) surface complexes bearing chelating catecholato ligands for enhanced band-gap reduction
(2023)
Protonolysis reactions between dimethylamido titanium(IV) catecholate [Ti(CAT)(NMe2)2]2 and neopentanol or tris(tert-butoxy)silanol gave catecholato-bridged dimers [(Ti(CAT)(OCH2tBu)2)(HNMe2)]2 and [Ti(CAT){OSi(OtBu)3}2(HNMe2)2]2, respectively. Analogous reactions using the dimeric dimethylamido titanium(IV) (3,6-di-tert-butyl)catecholate [Ti(CATtBu2-3,6)(NMe2)2]2 yielded the monomeric Ti(CATtBu2-3,6)(OCH2tBu)2(HNMe2)2 and Ti(CATtBu2-3,6)[OSi(OtBu)3]2(HNMe2)2. The neopentoxide complex Ti(CATtBu2-3,6)(OCH2tBu)2(HNMe2)2 engaged in further protonolysis reactions with Si–OH groups and was consequentially used for grafting onto mesoporous silica KIT-6. Upon immobilization, the surface complex [Ti(CATtBu2-3,6)(OCH2tBu)2(HNMe2)2]@[KIT-6] retained the bidentate chelating geometry of the catecholato ligand. This convergent grafting strategy was compared with a sequential and an aqueous approach, which gave either a mixture of bidentate chelating species with a bipodally anchored Ti(IV) center along with other physisorbed surface species or not clearly identifiable surface species. Extension of the convergent and aqueous approaches to anatase mesoporous titania (m-TiO2) enabled optical and electronic investigations of the corresponding surface species, revealing that the band-gap reduction is more pronounced for the bidentate chelating species (convergent approach) than for that obtained via the aqueous approach. The applied methods include X-ray photoelectron spectroscopy, ultraviolet photoelectron spectroscopy, and solid-state UV/vis spectroscopy. The energy-level alignment for the surface species from the aqueous approach, calculated from experimental data, accounts for the well-known type II excitation mechanism, whereas the findings indicate a distinct excitation mechanism for the bidentate chelating surface species of the material [Ti(CATtBu2-3,6)(OCH2tBu)2(HNMe2)2]@[m-TiO2].
The Commitment of Traders report (CoT) has been around for over 30 years, consistently revealing the futures positions of key market players. This study's primary aim is to use the comprehensive data from the Commitment of Traders reports to develop a short-term reversal trading strategy. Against the benchmark, a S&P 500 buy-and-hold approach with a Sharpe ratio of 1.07, the CoT long only strategy generated significant results in six individual markets. Extending the strategy to long-and-short, two markets outperformed the benchmark significantly. However, a scenario analysis indicated underperformance of the CoT strategy when traded in a portfolio, confirming that the chosen strategy parameters could not generate excess Sharpe ratios. Our results indicate that the Commodity Futures Trading Commission, more specifically the CoT report, contributed to efficient derivatives market.
Purpose
The authors study the valuation effect of corporate diversification in the initial phase of the COVID-19 pandemic in 2020 in Europe.
Design/methodology/approach
Applying a cross-sectional regression model to a sample of public companies headquartered in the European Union, the authors investigate the existence of and the change in a diversification discount between 2018 and 2020. By applying the Excess Q methodology, the authors make an industry adjustment of diversified companies to measure the value effect of corporate diversification.
Findings
The authors find an economically and statistically significant diversification discount that increases from an average Excess Q of −0.05 in 2019 to −0.10 in 2020. The diversified companies' inferior fundamental financial performance in 2020 accompanies the discount. The results deviate from those of previous research, which mostly show a decrease in the diversification discount in economic crises, and thereby, shed doubt on whether diversification provides insurance against pandemic-induced adverse value effects.
Originality/valueThe study distinguishes the role of corporate diversification during recessionary periods by establishing that the valuation effect of diversification depends on the nature of the crisis. The analysis incorporates criticism of previous studies concerning a biased methodology and uniform data source by applying the Excess Q methodology and using FactSet industry segment data.
Polyester fibers are widely employed in a multitude of sectors and applications from the technical textiles to everyday life thanks to their durability, strength, and flexibility. Despite these advantages, polyester lacks in dyeability, adhesion of coating, hydrophilicity, and it is characterized by a low wettability respect to natural fibers. On this regard, beyond the harmful hydrophobic textile finishings of polyester fabrics containing fluorine-compounds, and in order to avoid pre-treatments, such as laser irradiation to improve their surface properties, research is moving towards the development of fluorine-free and safer coatings. In this work, the (3-glycidyloxypropyl)trimethoxysilane (GPTMS) and various long alkyl-chain alkoxysilanes were employed for the fabrication in the presence of a catalyst of a water-based superhydrophobic finishing for polyester fabrics with a simple sol-gel, non-fluorinated, sustainable approach and the dip-pad-dry-cure method. The finished polyester fabrics surface properties were investigated by static and dynamic water repellency tests. Additionally, the resistance to common water-based liquids, abrasion resistance, moisture adsorption, and air permeability measurements were performed. Scanning electron microscopy was employed to examine the micro- and nano-morphology of the functionalized polyester fabrics surfaces. The obtained superhydrophobic finishings displayed high water-based stain resistance as well as good hydrophobicity after different cycles of abrasion.
Unternehmertum spielt sowohl für die Entwicklung afrikanischer Länder eine Rolle, als auch für ausländische Unternehmen mit Markteintrittsplänen. Die infrastrukturellen und institutionellen Rahmenbedingungen für Unternehmertum sind nach wie vor schwierig, wobei aber die fortschreitende Digitalisierung zu einer zunehmend aktiven Start-Up Szene in vielen afrikanischen Ländern führt. Nach wie vor existiert ein Mismatch zwischen den Bereichen in denen Start-Ups entstehen und den Bereichen, wo ausländische Unternehmen Partner für den Markteintritt suchen. Somit bleibt es trotz positiver Entwicklung beim Unternehmertum in absehbarer Zeit schwierig adäquate Partner zu finden.
Artificial intelligence is considered to be a significant technology for driving the future evolution of smart manufacturing environments. At the same time, automated guided vehicles (AGVs) play an essential role in manufacturing systems due to their potential to improve internal logistics by increasing production flexibility. Thereby, the productivity of the entire system relies on the quality of the schedule, which can achieve production cost savings by minimizing delays and the total makespan. However, traditional scheduling algorithms often have difficulties in adapting to changing environment conditions, and the performance of a selected algorithm depends on the individual scheduling problem. Therefore, this paper aimed to analyze the scheduling problem classes of AGVs by applying design science research to develop an algorithm selection approach. The designed artifact addressed a catalogue of characteristics that used several machine learning algorithms to find the optimal solution strategy for the intended scheduling problem. The contribution of this paper is the creation of an algorithm selection method that automatically selects a scheduling algorithm, depending on the problem class and the algorithm space. In this way, production efficiency can be increased by dynamically adapting the AGV schedules. A computational study with benchmark literature instances unveiled the successful implementation of constraint programming solvers for solving JSSP and FJSSP scheduling problems and machine learning algorithms for predicting the most promising solver. The performance of the solvers strongly depended on the given problem class and the problem instance. Consequently, the overall production performance increased by selecting the algorithms per instance. A field experiment in the learning factory at Reutlingen University enabled the validation of the approach within a running production scenario.
Erst die Corona-Pandemie, dann der Krieg in der Ukraine und die Energiekrise. Es scheint als rutschten wir von einer Katastrophe in die andere ohne zu wissen was als Nächstes kommt. Wir müssen uns der Frage stellen, wie wir solchen Krisen zukünftig begegnen können.
Auch die Forscherinnen und Forscher an der Hochschule Reutlingen leisten einen Beitrag dazu, unsere Gesellschaft widerstandsfähiger und robuster zu machen – sei es durch pfiffige Lösungen für die Energiekrise, durch kompetente Beratung zu Ressourceneffizienz und Lieferketten oder durch aktuelle Forschungsansätze zu resilienten IT-Strukturen und einer resilienten Wirtschaft.
Supply chains have evolved into dynamic, interconnected supply networks, which increases the complexity of achieving end-to-end traceability of object flows and their experienced events. With its capability of ensuring a secure, transparent, and immutable environment without relying on a trusted third party, the emerging blockchain technology shows strong potential to enable end-to-end traceability in such complex multitiered supply networks. This paper aims to overcome the limitations of existing blockchain-based traceability architectures regarding their object-related event mapping ability, which involves mapping the creation and deletion of objects, their aggregation and disaggregation, transformation, and transaction, in one holistic architecture. Therefore, this paper proposes a novel ‘blueprint-based’ token concept, which allows clients to group tokens into different types, where tokens of the same type are non-fungible. Furthermore, blueprints can include minting conditions, which, for example, are necessary when mapping assembly processes. In addition, the token concept contains logic for reflecting all conducted object-related events in an integrated token history. Finally, for validation purposes, this article implements the architecture’s components in code and proves its applicability based on the Ethereum blockchain. As a result, the proposed blockchain-based traceability architecture covers all object-related supply chain events and proves its general-purpose end-to-end traceability capabilities of object flows.
Cytocompatibility analyses of new implant materials or biomaterials are not only prescribed by the Medical Device Regulation (MDR), as defined in the DIN ISO Norm 10993-5 and -12, but are also increasingly replacing animal testing. In this context, jellyfish collagen has already been established as an alternative to mammalian collagen in different cell culture conditions, but a lack of knowledge exists about its applicability for cytocompatibility analyses of biomaterials. Thus, the present study was conducted to compare well plates coated with collagen type 0 derived from Rhizostoma pulmo with plates coated with bovine and porcine collagen. The coated well plates were analysed in vitro for their cytocompatibility, according to EN ISO 10993-5/−12, using both L929 fibroblasts and MC3T3 pre-osteoblasts. Thereby, the coated well plates were compared, using established materials as positive controls and a cytotoxic material, RM-A, as a negative control. L929 cells exhibited a significantly higher viability (#### p < 0.0001), proliferation (## p < 0.01), and a lower cytotoxicity (## p < 0.01 and # p < 0.05)) in the Jellagen® group compared to the bovine and porcine collagen groups. MC3T3 cells showed similar viability and acceptable proliferation and cytotoxicity in all collagen groups. The results of the present study revealed that the coating of well plates with collagen Type 0 derived from R. pulmo leads to comparable results to the case of well plates coated with mammalian collagens. Therefore, it is fully suitable for the in vitro analyses of the cytocompatibility of biomaterials or medical devices.
This paper presents a description model for smart, connected devices used in a manufacturing context. Similar to the wide spread adoption of smart products for personal and private usage, recent developments lead to a plethora of devices offering a variety of features and capabilities. Manufacturing companies undergoing digital transformation demand guidance with respect to the systematic introduction of smart, connected devices. The introduction of smart connected devices constitutes a strategic decision cost due to the high future committed cost after introduction and maintaining a smart device fleet by a vendor. This paper aims to support the introduction efforts by classifying the devices and thus helping companies identify their specific requirements for smart, connected devices before initiating widespread procurement. By mapping the features of these devices based on various attributes, allows the clustering of smart, connected devices including a requirement list for their implementation on the shopfloor. Four individual commercially available smart connected devices were analyzed using the description model.
Parallel grippers offer multiple applications thanks to their flexibility. Their application field ranges from aerospace and automotive to medicine and communication technologies. However, the application of grippers has the problem of exhibition wear and errors during the execution of their operation. This affects the performance of the gripper. In this context, the remaining useful life (RUL) defines the remaining lifespan until failure for an asset at a particular time of operation occurs. The exact lifespan of an asset is uncertain, thus the RUL model and estimation must be derived from available sources of information. This paper presents a method for the estimation of the RUL for a two-jaw parallel gripper. After the introduction to the topic, an overview of existing literature and RUL methods are presented. Subsequently, the method for estimating the RUL of grippers is explained. Finally, the results are summarized and discussed before the outlook and further challenges are presented.
In diesem Beitrag wird der Einfluss von Zuschauern nach den pandemiebedingten Geisterspielen auf den Heimvorteil in der ersten Fußball-Bundesliga analysiert. Für die empirische Untersuchung werden die fünf Spielzeiten 2017/18 bis 2021/22 betrachtet. Während in der Geisterspielphase in der Saison 2019/20 der Heimvorteil vollständig verschwindet, steigt der Heimvorteil in der zweiten Geisterspielphase in der Saison 2020/21 mit der Zeit wieder auf vorpandemisches Niveau an. In der Saison 2021/22 ist nach einer kurzen Phase mit eingeschränkten Zuschauerkapazitäten ein signifikant größerer Heimvorteil als in der Zeit vor der Pandemie zu beobachten. Der überdurchschnittlich positive Effekt der Zuschauer in dieser letzten Phase verschwindet mit der Zeit trotz steigender Zuschauerzahlen. Der Einfluss von Fans auf den Heimvorteil ist insgesamt insbesondere auf psychologische Effekte auf die Spieler der Heimmannschaften zurückzuführen.
Artificial Intelligence (AI) in der Markenführung: Künstliche Neuronale Netze zur Markenimagemessung
(2023)
Da Künstliche Neuronale Netze die Modellierung nichtlinearer und vielschichtiger Beziehungen ermöglichen, befasst sich dieser Beitrag mit deren Einsatzmöglichkeiten für die methodisch anspruchsvolle Analyse und Messung des Markenimages. Zur Veranschaulichung des konzeptionellen Ansatzes wird am empirischen Beispiel des Sportartikelherstellers adidas ein mehrschichtiges Künstliches Neuronales Netz zwischen den Bewertungen spezifischer Markenattribute und der Gesamtbewertung der Marke erzeugt. Auf der Grundlage einer Analyse der Verbindungsgewichte des Künstliches Neuronales Netzes wird die Bedeutung verschiedener Markenattribute für die Markenbewertung gemessen, wodurch sich konkrete Implikationen für die Praxis der Markenführung ableiten lassen.
The dawn of the 21st Century has witnessed a tremendous increase in trade pacts among nations, resulting in renewed hopes for sustainable enterprise development in emerging economies worldwide. Ghana and other sub-Saharan African (SSA) countries have signed onto several North-South and South-South free trade agreements with the hope of strengthening their presence in the international trade arena, and to promote economic growth in SSA. For over two decades, however, very little has changed, and many have dashed their high hopes as enterprises continue to struggle in SSA. Not even the African Continental Free Trade Agreement (AfCFTA) could renew the hopes of sceptics. Several studies opined that enterprises in SSA could improve their domestic and international competitiveness by establishing mutually beneficial partnerships with their counterparts from the Global North and South. This study delved into the issues that affect North-South and South-South business collaborations and recommends key success factors that could help promote mutually beneficial cross-border business partnerships. The research includes both literature and empirical information on the key success factors of business partnerships between African enterprises as well as between African enterprises and firms from the Global North. We approached the study qualitatively using a phenomenological research design. Research participants included important stakeholders in Africa and Europe's international trade and sustainable enterprise development ecosystem. The study identified several challenges with the current business collaborations and recommended new ways of making such partnerships more beneficial.
In order to ensure sufficient recovery of the human body and brain, healthy sleep is indispensable. For this purpose, appropriate therapy should be initiated at an early stage in the case of sleep disorders. For some sleep disorders (e.g., insomnia), a sleep diary is essential for diagnosis and therapy monitoring. However, subjective measurement with a sleep diary has several disadvantages, requiring regular action from the user and leading to decreased comfort and potential data loss. To automate sleep monitoring and increase user comfort, one could consider replacing a sleep diary with an automatic measurement, such as a smartwatch, which would not disturb sleep. To obtain accurate results on the evaluation of the possibility of such a replacement, a field study was conducted with a total of 166 overnight recordings, followed by an analysis of the results. In this evaluation, objective sleep measurement with a Samsung Galaxy Watch 4 was compared to a subjective approach with a sleep diary, which is a standard method in sleep medicine. The focus was on comparing four relevant sleep characteristics: falling asleep time, waking up time, total sleep time (TST), and sleep efficiency (SE). After evaluating the results, it was concluded that a smartwatch could replace subjective measurement to determine falling asleep and waking up time, considering some level of inaccuracy. In the case of SE, substitution was also proved to be possible. However, some individual recordings showed a higher discrepancy in results between the two approaches. For its part, the evaluation of the TST measurement currently does not allow us to recommend substituting the measurement method for this sleep parameter. The appropriateness of replacing sleep diary measurement with a smartwatch depends on the acceptable levels of discrepancy. We propose four levels of similarity of results, defining ranges of absolute differences between objective and subjective measurements. By considering the values in the provided table and knowing the required accuracy, it is possible to determine the suitability of substitution in each individual case. The introduction of a “similarity level” parameter increases the adaptability and reusability of study findings in individual practical cases.
Digitalisierung in Corporate Mergers & Acquisitions (M&A)-Prozessen birgt ein erhebliches Potenzial zur Effizienz- und Effektivitätssteigerung, erfährt jedoch bislang in der betrieblichen Praxis nur eine geringe Aufmerksamkeit. Dieser Beitrag schlägt angesichts dessen ein Reifegradmodell vor, womit sich der Ist-Stand der digitalen Reife eines Unternehmens bei Corporate M&A ermitteln und darauf aufbauend Optimierungspotenziale identifizieren lassen. Grundlage der Modellerstellung sind einerseits eine Analyse der vorhandenen Reifegradmodelle und andererseits Interviews mit M&A-Experten unterschiedlicher Unternehmen.
The scoring of sleep stages is one of the essential tasks in sleep analysis. Since a manual procedure requires considerable human and financial resources, and incorporates some subjectivity, an automated approach could result in several advantages. There have been many developments in this area, and in order to provide a comprehensive overview, it is essential to review relevant recent works and summarise the characteristics of the approaches, which is the main aim of this article. To achieve it, we examined articles published between 2018 and 2022 that dealt with the automated scoring of sleep stages. In the final selection for in-depth analysis, 125 articles were included after reviewing a total of 515 publications. The results revealed that automatic scoring demonstrates good quality (with Cohen's kappa up to over 0.80 and accuracy up to over 90%) in analysing EEG/EEG + EOG + EMG signals. At the same time, it should be noted that there has been no breakthrough in the quality of results using these signals in recent years. Systems involving other signals that could potentially be acquired more conveniently for the user (e.g. respiratory, cardiac or movement signals) remain more challenging in the implementation with a high level of reliability but have considerable innovation capability. In general, automatic sleep stage scoring has excellent potential to assist medical professionals while providing an objective assessment.
Die folgende Veröffentlichung ist ein Konferenzband, der im Sommersemester 2023 stattgefundenen Studierendenkonferenz Informatics Inisde, die für die Fakultät Informatik und die Studierenden ein besonderes Ereignis ist. Mit der Veröffentlichung Ihrer Artikel in diesem Konferenzband haben die Studierende eine handfeste Publikation, die durch ein Peer-Review inhaltlich qualitätsgesichert ist.
In diesem Jahr gibt es eine neue Herausforderung: Seit dem Jahr 2022 steht ChatGPT von OpenAI zur Verfügung, das verblüffende Texte mit nachvollziehbarer Argumentation verfassen kann. Eine Nutzung des Werkzeugs für die Erstellung eines wissenschaftlichen Artikels ist denkbar und gleichzeitig schwer zu beweisen. Ein kritischer Umgang mit Technologie ist wichtiger als ein pauschales Verbot. Dennoch braucht es Regeln im Umgang mit Künstlicher Intelligenz, die einen ethisch richtigen Einsatz solcher Werkzeuge begrenzt. Umso wichtiger ist es, dass umfassender Sachverstand und kritisches Denken vermittelt wird, damit mögliche Fehler oder Plagiatsfälle entlarvt werden können.
Damit sind wir mitten im Thema: Informatik ist allgegenwärtig und in äußerst vielen Produkten in der Industrie und des täglichen Lebens vorhanden. Die vielfältigen Aufsätze dieser Konferenz zeigen das. Sehen Sie selbst, wie breit die Verfahren, Algorithmen, Methoden und Technologieanwendungen sind: Von Augmented-Reality, über Videoübertragung im Operationssaal, hin zu Standards für strukturierten Daten und Künstlicher Intelligenz zeigen die Beiträge doch, wie weit läufig die Informatik inzwischen ist. Allen gemeinsam ist eines: Die menschzentrierte Anwendung von Technologie, die in dem Master Human-centered Computing als Basis aller Veranstaltungen aufgefasst werden.
Background: Polysomnography (PSG) is the gold standard for detecting obstructive sleep apnea (OSA). However, this technique has many disadvantages when using it outside the hospital or for daily use. Portable monitors (PMs) aim to streamline the OSA detection process through deep learning (DL).
Materials and methods: We studied how to detect OSA events and calculate the apnea-hypopnea index (AHI) by using deep learning models that aim to be implemented on PMs. Several deep learning models are presented after being trained on polysomnography data from the National Sleep Research Resource (NSRR) repository. The best hyperparameters for the DL architecture are presented. In addition, emphasis is focused on model explainability techniques, concretely on Gradient-weighted Class Activation Mapping (Grad-CAM).
Results: The results for the best DL model are presented and analyzed. The interpretability of the DL model is also analyzed by studying the regions of the signals that are most relevant for the model to make the decision. The model that yields the best result is a one-dimensional convolutional neural network (1D-CNN) with 84.3% accuracy.
Conclusion: The use of PMs using machine learning techniques for detecting OSA events still has a long way to go. However, our method for developing explainable DL models demonstrates that PMs appear to be a promising alternative to PSG in the future for the detection of obstructive apnea events and the automatic calculation of AHI.
Hybrides Arbeiten in digitalen Prozessen sollte eigentlich sehr gut funktionieren. Durch die Digitalisierung werden Schnittstellen zwischen Abteilungen und Funktionen standardisiert sowie Abläufe durch Workflow-Systeme vorgegeben und ganz oder teilweise automatisiert. Es werden Aufgaben eindeutig zugewiesen, Datenverluste verhindert und Abweichungen vermieden. Die Nachteile der häufig noch etablierten tayloristischen, funktionsorientierten Silo-Aufbauorganisation in administrativen Bereichen werden dadurch ebenso kompensiert wie die räumliche Trennung der beteiligten Personen in einer hybriden Arbeitswelt.
Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to the variety of scanners and imaging protocols. Over the last years, the BraTS Challenge has provided a large number of multi-institutional MRI scans as a benchmark for glioma segmentation algorithms. This paper describes our contribution to the BraTS 2022 Continuous Evaluation challenge. We propose a new ensemble of multiple deep learning frameworks namely, DeepSeg, nnU-Net, and DeepSCAN for automatic glioma boundaries detection in pre-operative MRI. It is worth noting that our ensemble models took first place in the final evaluation on the BraTS testing dataset with Dice scores of 0.9294, 0.8788, and 0.8803, and Hausdorf distance of 5.23, 13.54, and 12.05, for the whole tumor, tumor core, and enhancing tumor, respectively. Furthermore, the proposed ensemble method ranked first in the final ranking on another unseen test dataset, namely Sub-Saharan Africa dataset, achieving mean Dice scores of 0.9737, 0.9593, and 0.9022, and HD95 of 2.66, 1.72, 3.32 for the whole tumor, tumor core, and enhancing tumor, respectively.
Purpose – This paper explores, which employer attractiveness attributes Generation Z (Gen Z) talents prioritize. Comparing the findings for female and male participants, this study examines whether gender-specific work value orientations prevail among Gen Z talents and impact their expectations toward employers.
Design/methodology/approach – A survey was conducted among 308 students of business, economics and management in Germany. Data were collected using the employer attractiveness scale of Berthon and colleagues (2005) complemented by an additional dimension focusing on work–life balance.
Findings – Findings indicate that Gen Z talents primarily expect a fun work environment, a positive team atmosphere and supportive relations with colleagues and superiors. Application aspects and work–life balance enabling services are expected the least. Expectations of four of the six attributes measured differ significantly among women and men, indicating that traditional gender assumptions continue to be reflected in the work value orientations of Gen Z talents.
Research limitations/implications – The sample was limited to business, economics and management students in Germany. Additional research should include a wider variety of respondents of different disciplines and countries.
Practical implications – Practical implications refer to emphasizing the social value of employment in the employee value proposition and customizing employer branding activities by gender.
Originality/value – This study contributes to the literature by empirically determining which employer attractiveness attributes Gen Z talents expect and whether and how these expectations vary by gender.
AI-based prediction and recommender systems are widely used in various industry sectors. However, general acceptance of AI-enabled systems is still widely uninvestigated. Therefore, firstly we conducted a survey with 559 respondents. Findings suggested that AI-enabled systems should be fair, transparent, consider personality traits and perform tasks efficiently. Secondly, we developed a system for the Facial Beauty Prediction (FBP) benchmark that automatically evaluates facial attractiveness. As our previous experiments have proven, these results are usually highly correlated with human ratings. Consequently they also reflect human bias in annotations. An upcoming challenge for scientists is to provide training data and AI algorithms that can withstand distorted information. In this work, we introduce AntiDiscriminationNet (ADN), a superior attractiveness prediction network. We propose a new method to generate an unbiased convolutional neural network (CNN) to improve the fairn ess of machine learning in facial dataset. To train unbiased networks we generate synthetic images and weight training data for anti-discrimination assessments towards different ethnicities. Additionally, we introduce an approach with entropy penalty terms to reduce the bias of our CNN. Our research provides insights in how to train and build fair machine learning models for facial image analysis by minimising implicit biases. Our AntiDiscriminationNet finally outperforms all competitors in the FBP benchmark by achieving a Pearson correlation coefficient of PCC = 0.9601.
Der pH-Wert der menschlichen Haut liegt nicht im neutralen Bereich, sondern ist mit Werten von 3,5-6 – je nach Körperstelle – leicht Sauer. Das bietet der Kommensalen Hautflora einen geeigneten Lebensraum, wirkt jedoch abtötend auf einige pathogene Mikroorganismen und inaktivierend auf einige Viren. Dieser Säureschutzmantel der Haut stellt somit eine erste äußere Schutzschicht vor dem Befall von Krankheitserregern dar. Ein entsprechender Oberflächen-pH-Wert auf Textilien kann dazu beitragen, die Übertragung von Krankheitserregern durch die Kleidung von Mitarbeitern im Gesundheitswesen zu minimieren und gleichzeitig keinen negativen Einfluss auf die hauteigene Flora auszuüben. Zudem kann die Besiedlung von z.B. Bettwäsche durch pathogene Mikroorganismen vermindert werden. Einen positiven Einfluss kann dies zudem auf die bakterienassoziierte Geruchsbildung auf Funktionskleidung haben.
The pH value of the human skin is not in the neutral range but is slightly acidic with values of – depending on the body part – 3.5 to 6. This provides a suitable habitat for the commensal skin floral but has a killing effect on some pathogenic micro-organisms and an inactivating effect on some viruses. This protective acid mantle of the skin thus represents a first external protective layer against infestation by pathogens. An appropriate surface pH on textiles can help to minimize the transmission of pathogens through the clothing of healthcare workers while at the same time not exerting a negative influence on the skin’s own flora. In addition, the colonization of e.g. bed linen by pathogenic microorganisms can be reduced. This can also have a positive influence on bacteria-associated odor formation on functional clothing.
Diese Studie untersucht den kurzfristigen Einfluss der Tagespflege auf die kindliche Entwicklung im Vergleich zur Betreuung in der Kita. Internationale Studien deuten darauf hin, dass der Besuch einer Tagespflege im Vergleich zur Kita eher negative Auswirkungen auf Kinder hat. Mithilfe der Neugeborenen-Kohorte des NEPS können wir evaluieren, ob dies auch im deutschen Kontext gilt. Wir nutzen zwei verschiedene methodische Ansätze, um den Effekt der Tagespflege zu schätzen. Unsere Ergebnisse zeigen, dass die Tagespflege für die Mehrzahl der untersuchten Entwicklungsindikatoren keinen statistisch signifikant schlechteren Einfluss auf die kindliche Entwicklung hat, außer im Bereich der Habituation.
Purpose
In recognising the key role of business intelligence and big data analytics in influencing companies’ decision-making processes, this paper aims to codify the main phases through which companies can approach, develop and manage big data analytics.
Design/methodology/approach
By adopting a research strategy based on case studies, this paper depicts the main phases and challenges that companies “live” through in approaching big data analytics as a way to support their decision-making processes. The analysis of case studies has been chosen as the main research method because it offers the possibility for different data sources to describe a phenomenon and subsequently to develop and test theories.
Findings
This paper provides a possible depiction of the main phases and challenges through which the approach(es) to big data analytics can emerge and evolve over time with reference to companies’ decision-making processes.
Research limitations/implications
This paper recalls the attention of researchers in defining clear patterns through which technology-based approaches should be developed. In its depiction of the main phases of the development of big data analytics in companies’ decision-making processes, this paper highlights the possible domains in which to define and renovate approaches to value. The proposed conceptual model derives from the adoption of an inductive approach. Despite its validity, it is discussed and questioned through multiple case studies. In addition, its generalisability requires further discussion and analysis in the light of alternative interpretative perspectives.
Practical implications
The reflections herein offer practitioners interested in company management the possibility to develop performance measurement tools that can evaluate how each phase can contribute to companies’ value creation processes.
Originality/value
This paper contributes to the ongoing debate about the role of digital technologies in influencing managerial and social models. This paper provides a conceptual model that is able to support both researchers and practitioners in understanding through which phases big data analytics can be approached and managed to enhance value processes.
Digital twins deployed in production are important in practice and interesting for research. Currently, mostly structured data coming from e.g., sensors and timestamps of related stations, are integrated into Digital Twins. However, semi- and unstructured data are also important to display the current status of a digital twin (e.g., of a machinery or produced good). Process Mining and Text Mining in combination can be used to support the use of log file data to understand the current state of the process as well as highlight issues. Therefore, issue related reactions can be taken more quickly, targeted and cost oriented. Applying a design science research approach; here a prototype as an artefact based on derived requirements is developed. This prototype helps to understand and to clarify the possibilities of Process Mining and Text Mining based on log data for production related Digital Twins. Contributions for practice and research are described. Furthermore, limitations of the research and future opportunities are pointed out.
Sleep is essential to physical and mental health. However, the traditional approach to sleep analysis—polysomnography (PSG)—is intrusive and expensive. Therefore, there is great interest in the development of non-contact, non-invasive, and non-intrusive sleep monitoring systems and technologies that can reliably and accurately measure cardiorespiratory parameters with minimal impact on the patient. This has led to the development of other relevant approaches, which are characterised, for example, by the fact that they allow greater freedom of movement and do not require direct contact with the body, i.e., they are non-contact. This systematic review discusses the relevant methods and technologies for non-contact monitoring of cardiorespiratory activity during sleep. Taking into account the current state of the art in non-intrusive technologies, we can identify the methods of non-intrusive monitoring of cardiac and respiratory activity, the technologies and types of sensors used, and the possible physiological parameters available for analysis. To do this, we conducted a literature review and summarised current research on the use of non-contact technologies for non-intrusive monitoring of cardiac and respiratory activity. The inclusion and exclusion criteria for the selection of publications were established prior to the start of the search. Publications were assessed using one main question and several specific questions. We obtained 3774 unique articles from four literature databases (Web of Science, IEEE Xplore, PubMed, and Scopus) and checked them for relevance, resulting in 54 articles that were analysed in a structured way using terminology. The result was 15 different types of sensors and devices (e.g., radar, temperature sensors, motion sensors, cameras) that can be installed in hospital wards and departments or in the environment. The ability to detect heart rate, respiratory rate, and sleep disorders such as apnoea was among the characteristics examined to investigate the overall effectiveness of the systems and technologies considered for cardiorespiratory monitoring. In addition, the advantages and disadvantages of the considered systems and technologies were identified by answering the identified research questions. The results obtained allow us to determine the current trends and the vector of development of medical technologies in sleep medicine for future researchers and research.
Flame-retardant finishing of cotton fabrics using DOPO functionalized alkoxy- and amido alkoxysilane
(2023)
In the present study, DOPO-based alkoxysilane (DOPO-ETES) and amido alkoxysilane (DOPO-AmdPTES) were synthesized by one-step and without by-products as halogen-free flame retardants. The flame retardants were applied on cotton fabric utilizing sol–gel method and pad-dry-cure finishing process. The flame retardancy, the thermal stability and the combustion ehaviour of treated cotton were evaluated by surface and bottom edge ignition flame test (according to EN ISO 15025), thermogravimetric analysis (TGA) and micro-scale combustion calorimeter (MCC). Unlike CO/DOPO-ETES sample, cotton treated with DOPO-AmdPTES nanosols exhibits self-extinguishing ehaviour with high char residue, an improvement of the LOI value and a significant reduction of the PHRR, HRC and THR compared to pristine cotton. Cotton finished with DOPO-AmdPTES reveals a semi-durability after ten laundering cycles keeping the flame-retardant properties unchanged. According to the results obtained from TGA-FTIR, Py-GC/MS and XPS, the major activity of flame retardant occurs in the condensed phase via catalytic induced char formation as physical barrier along with the activity in the gas phase derived mainly from the dilution effect. The early degradation of CO/DOPO-AmdPTES compared to CO/DOPO-ETES, triggered by the cleavage of the weak bond between P and C=O, as the DFT study indicated, provides the beneficial effect of this flame retardant on the fire resistance of cellulose.
Wertschätzung zählt
(2023)
Wie steht es mit den Sitten im B2B-Geschäft? Im Beitrag werden Wahrnehmung und Ursachen für den Sittenwandel im wirtschaftlichen Kontext in Deutschland und der Schweiz beleuchtet. Anhand einer Analyse der Werteforschung und Experteninterviews im B2B-Sales werden die Erscheinungsformen des Sittenwandels kritisch untersucht. Die Ergebnisse zeigen, dass Wertschätzung, Respekt und Vertrauen im Vertriebsbereich zwar einen hohen Wert besitzen, aber oft missachtet werden.
Die vorliegende Studie beschäftigt sich mit der Verbreitung des Customer-Success-Managements im deutschsprachigen Mittelstand und der Frage, wie eine erfolgreiche Implementierung dort durchgeführt werden kann. Die Ergebnisse zeigen, dass, vorgelagert zum eigentlichen Customer-Success-Management-Prozess, interne sowie externe Voraussetzungen im deutschsprachigen Mittelstand geschaffen werden müssen, um eine nachhaltige Implementierung gewährleisten zu können. Dazu zählt die Transformation vom reinen Produktfokus hin zu einer kunden- und servicezentrierten Unternehmensstrategie. Voraussetzung dafür ist die Erhöhung des Digitalisierungsgrads der Produkte und internen Prozesse sowie ein aktives Change-Management.
Dieser Beitrag untersucht, wer in Deutschland Bildungsminister:in wird. Zur Klärung dieser Frage entwickelten wir einen Datensatz, der die biografischen Merkmale aller Bildungsminister:innen der deutschen Bundesländer zwischen 1950 und 2020 enthält. Als Beispiel für die Nutzung des Datensatzes untersuchen wir die beiden Merkmale Geschlecht und frühere Berufserfahrung und verknüpfen diese Merkmale mit Indikatoren für die Größe und Entwicklung des Bildungsbudgets und die Dauer der Amtszeit. Wir zeigen, dass zwischen 1950 und 2020 deutlich mehr Männer als Frauen zum/zur Bildungsminister:in ernannt wurden, unabhängig davon, welche Parteien die Bildungsminister:innen stellten. Außerdem verfügt die Mehrheit der Bildungsminister:innen bei Amtsantritt nicht über vorherige Berufserfahrung als Lehrer:in. Die meisten Bildungsminister:innen haben jedoch bereits politische Erfahrung, wenn sie ihr Amt antreten. Unsere Datenbank, die die erste umfassende Erhebung biografischer Merkmale von Bildungsminister:innen in den deutschen Bundesländern enthält, steht allen interessierten Forscher:innen zur Verfügung.
Der pH-Wert der menschlichen Haut liegt nicht im neutralen Bereich, sondern ist mit Werten von 3,5-6 – je nach Körperstelle – leicht Sauer. Das bietet der Kommensalen Hautflora einen geeigneten Lebensraum, wirkt jedoch abtötend auf einige pathogene Mikroorganismen und inaktivierend auf einige Viren. Dieser Säureschutzmantel der Haut stellt somit eine erste äußere Schutzschicht vor dem Befall von Krankheitserregern dar. Ein entsprechender Oberflächen-pH-Wert auf Textilien kann dazu beitragen, die Übertragung von Krankheitserregern durch die Kleidung von Mitarbeitern im Gesundheitswesen zu minimieren und gleichzeitig keinen negativen Einfluss auf die hauteigene Flora auszuüben. Zudem kann die Besiedlung von z.B. Bettwäsche durch pathogene Mikroorganismen vermindert werden. Einen positiven Einfluss kann dies zudem auf die bakterienassoziierte Geruchsbildung auf Funktionskleidung haben.
The fifth mobile communications generation (5G) can lead to a substantial change in companies enabling the full capability of wireless industrial communication. 5G with its key features of providing Enhanced Mobile Broadband, Ultra-Reliable and Low-Latency Communication, and Massive Machine Type Communication will support the implementation of Industry 4.0 applications. In particular, the possibility to set-up Non-Public Networks provides the opportunity of 5G communication in factories and ensures sole access to the 5G infrastructure offering new opportunities for companies to implement innovative mobile applications. Currently there exist various concepts, ideas, and projects for 5G applications in an industrial environment. However, the global rollout of 5G systems is a continuous process based on various stages defined by the global initiative 3rd Generation Partnership Project that develops and specifies the 5G telecommunication standard. Accordingly, some services are currently still far from their final performance capability or not yet implemented. Additionally, research lacks in clarifying the general suitability of 5G regarding frequently mentioned 5G use cases. This paper aims to identify relevant 5G use cases for intralogistics and evaluates their technical requirements regarding their practical feasibility throughout the upcoming 5G specifications.
The blockchain technology represents a decentralised database that stores information securely in immutable data blocks. Regarding supply chain management, these characteristics offer potentials in increasing supply chain transparency, visibility, automation, and efficiency. In this context, first token-based mapping approaches exist to transfer certain manufacturing processes to the blockchain, such as the creation or assembly of parts as well as their transfer of ownership. This paper proposes a prototypical blockchain application that adopts an authority concept and a concept of smart non-fungible tokens. The application enables the mapping of complex products in dynamic supply chains that require the auditability of changeable assembling processes on the blockchain. Finally, the paper demonstrates the practical feasibility of the proposed application based on a prototypical implementation created on the Ethereum blockchain.
Das Interview geht der Frage nach: Verändern neue Geschäftsmodelle die Unternehmenssteuerung? Dazu machen die Diskussionspartner am Beispiel der Automobilbranche auf vielfältige Veränderungen und Entwicklungen aufmerksam. Zentral ist die Herausbildung neuer Geschäftsmodelle, die die Funktionsweise und den Marktauftritt der Unternehmen zeitgerecht und wirtschaftlich erfolgreich gestalten sollen. Ebenso wichtig ist die Zusammenfassung der vielfältigen Steuerungsaktivitäten in einem Steuerungsmodell und deren fortlaufende Abstimmung mit den sich aus dem Geschäftsmodell jeweils ergebenden Steuerungsanforderungen.
Purpose
Job advertisements are important means of communicating role expectations for management accountants to the labor market. They provide information about which roles are sought and expected. However, which roles are communicated in job advertisements is unknown so far.
Design/methodology/approach
With a text-mining approach on a large sample of 889 job ads, the authors extract information on roles, type of firm and hierarchical position of the management accountant sought.
Findings
The results indicate an apparent mix of different role types with a strong focus on a classic watchdog role. However, the business partner role is more often sought for leadership positions or in family businesses and small- and medium-sized enterprises (SME).
Research limitations/implications
The main limitation is the lack of an agreed-upon measurement instrument for roles in job offers. The study results imply that corporate practice is not as theory-driven as is postulated and communicated in the management accounting community. This indicates the existence of a research-practice gap and tensions between different actors in the management accounting field.
Practical implications
The results challenge the current role discussion of professional organizations for management accountants as business partners.
Originality/value
The authors contribute the first study, which explicitly analyzes the communication of roles in job offers for management accountants. It indicates a discrepancy between scholarly discussion on roles and management accountants' work from an employer's perspective.
Artificial intelligence (AI) is one of the most promising technologies of the post-pandemic era. Cloud computing technology can simplify the process of developing AI applications by offering a variety of services, including ready-to-use tools to train machine learning (ML) algorithms. However, comparing the vast amount of services offered by different providers and selecting a suitable cloud service can be a major challenge for many firms. Also in academia, suitable criteria to evaluate this type of service remain largely unclear. Therefore, the overall aim of this work has been to develop a framework to evaluate cloud-based ML services. We use Design Science Research as our methodology and conduct a hermeneutic literature review, a vendor analysis, as well as, expert interviews. Based on our research, we present a novel framework for the evaluation of cloud-based ML services consisting of six categories and 22 criteria that are operationalized with the help of various metrics. We believe that our results will help organizations by providing specific guidance on how to compare and select service providers from the vast amount of potential suppliers.
Towards a sustainable future, looking beyond the system boundaries of a single manufacturing company is necessary to promote meaningful collaborations in terms of circular economy principles. In this context digital data processing technologies to connect the potential collaborators are seen as enablers to make use of proven collaborative circular business models (CCBMs). Since most of such data processing technologies rely on features to describe the entities involved, it is essential to provide guidance for identifying and selecting the relevant and most appropriate ones. Defining critical success factors (CSFs) is considered a suitable instrument to describe the decisive factors. A systematic literature review (SLR), followed by a qualitative synthesis is investigating two scientific fields of work, namely (1) the general relevant features of CCBMs and, (2) methodologies for determining CSFs. This results in the development of a conceptual framework which provides guidance for digital applications that perform further digital processing based on the relevant CSFs relating to the specific CCBM.
Die Coronapandemie hat Deutschland seit dem Frühjahr 2020 fest im Griff. Eine zentrale Maßnahme zur Verlangsamung der Ausbreitung des Coronavirus war von Beginn an die Schließung von Schulen. In einer ersten Studie wurden die Lernzeitverluste durch die Corona-bedingten Schulschließungen im Frühjahr 2020 quantifiziert (Wößmann, Freundl, Lergetporer, Grewenig, Werner & Zierow, 2020). Es zeigte sich, dass sich die Lernzeit der Schülerinnen und Schüler durch die Schulschließungen halbiert hatte und die Verluste bei leistungsschwächeren Schülerinnen und Schülern besonders groß waren. Im Frühjahr 2020 wurde die Verringerung der Lernzeit von den Schulen nicht kompensiert: Nur ein kleiner Teil der Schülerinnen und Schüler hatte in dieser Phase regelmäßigen Distanzunterricht und täglichen Kontakt mit Lehrkräften. Während der Sommer- und Herbstmonate seit der Phase der ersten Schulschließungen hatten Schulverwaltung, Schulen und Lehrkräfte Zeit, sich auf Distanzunterricht und digitale Lehrmethoden umzustellen, um Lernausfällen während etwaiger erneuter Schulschließungen entgegenzuwirken. Inwiefern dies dazu geführt hat, dass die Schülerinnen und Schüler während der Schulschließungen Anfang 2021 tatsächlich mehr Zeit mit Lernen verbracht haben als im Frühjahr 2020, ist jedoch bislang weitgehend unbekannt.
Um zu erfahren, mit welchen Aktivitäten die Schulkinder die Zeit der Schulschließungen Anfang 2021 verbracht haben, wurde erneut eine deutschlandweite Umfrage durchgeführt, diesmal unter mehr als 2.000 Eltern von Schulkindern. Die Ergebnisse liefern umfassende Einblicke in den Alltag von Schulkindern, Eltern und Schulen während der Schulschließungen Anfang 2021. Sie zeigen, wie viele Stunden die Schulkinder in dieser Phase mit Lernen und anderen kreativen und passiven Tätigkeiten verbracht haben, welche konkreten Maßnahmen die Schulen ergriffen haben, um den Schulbetrieb aufrechtzuerhalten, wie effektiv das Lernen zu Hause war, und wie die Eltern das häusliche Lernumfeld einschätzen. Dabei vergleichen wir die Aktivitäten während der Schulschließungen Anfang 2021 mit den Aktivitäten während der ersten Corona-bedingten Schulschließungen im Frühjahr 2020 sowie mit den Aktivitäten vor Corona (vgl. Wößmann et al., 2020). Wir berichten zudem Ergebnisse zum sozio-emotionalen Wohlbefinden der Kinder nach einem Jahr Coronapandemie und zu den Einschätzungen der Eltern, welche breiteren Auswirkungen die Schulschließungen auf verschiedene Lebensbereiche ihrer Kinder haben. Die Befragung liefert somit neue empirische Erkenntnisse über mögliche Folgen der Corona-Krise für den Bildungserfolg von Kindern in Deutschland. Dabei untersuchen wir auch, inwiefern sich die Auswirkungen der Schulschließungen zwischen leistungsstärkeren und -schwächeren Schülerinnen und Schülern sowie zwischen Akademikerkindern und Nicht-Akademikerkindern unterscheiden.
Auf dem Weg zu einer neuen Normalität in Schule und Bildung?! : Empfehlungen der Beitragenden
(2023)
Die im vorliegenden Band präsentierten Studien und Erkenntnisse zeigen die tiefen Einschnitte, die die Pandemie in Schule und Bildung hinterlassen hat. Zahlreiche Forschende, Expertinnen und Experten, aber auch engagierte Eltern, Kinder und Jugendliche wünschen sich in Anbetracht der Erfahrungen eine „neue“ Normalität für Schule und Bildung – eine Normalität, in der Bildungsungerechtigkeit wirksamer begegnet wird, die digitaler ist, … Wie könnte der Weg dahin aussehen?
Dieses Buch vermittelt die grundlegenden Kenntnisse für den Layoutentwurf digitaler und analoger Schaltungen. Neben den ingenieurwissenschaftlichen Grundlagen werden auch Werkzeugaspekte behandelt. Das Werk befähigt Ingenieure, einen Schaltplan oder eine Netzliste in eine Layoutdarstellung zur Fertigung eines integrierten Schaltkreises (IC) oder einer Leiterplatte umzusetzen. Nach einer einleitenden Übersicht zu Fertigungstechnologien, Besonderheiten der Mikroelektronik und den Aufgaben des Layoutentwurfs behandelt Kap. 2 zunächst die technologischen Grundlagen der IC-Fertigung. Darauf aufbauend werden nachfolgend alle Aspekte des Layoutentwurfs vertieft: Schnittstellen, Entwurfsregeln und Bibliotheken (Kap. 3), Entwurfsstile, -modelle und -flüsse (Kap. 4), Entwurfsschritte (Kap. 5), Besonderheiten des analogen IC-Entwurfs (Kap. 6) und schließlich Zuverlässigkeitsmaßnahmen (Kap. 7). Das Buch eignet sich als Lehrbuch in den Ingenieurwissenschaften und als Nachschlagewerk für Schaltungs- und Layoutentwickler in der Industrie.
Analog integrated circuit sizing is notoriously difficult to automate due to its complexity and scale; thus, it continues to heavily rely on human expert knowledge. This work presents a machine learning-based design automation methodology comprising pre-defined building blocks such as current mirrors or differential pairs and pre-computed look-up tables for electrical characteristics of primitive devices. Modeling the behavior of primitive devices around the operating point with neural networks combines the speed of equation-based methods with the accuracy of simulation-based approaches and, thereby, brings quality of life improvements for analog circuit designers using the gm/Id method. Extending this procedural automation method for human design experts, we present a fully autonomous sizing approach. Related work shows that the convergence properties of conventional optimization approaches improve significantly when acting in the electrical domain instead of the geometrical domain. We, therefore, formulate the circuit sizing task as a sequential decision-making problem in the alternative electrical design space. Our automation approach is based entirely on reinforcement learning, whereby abstract agents learn efficient design space navigation through interaction and without expert guidance. These agents’ learning behavior and performance are evaluated on circuits of varying complexity and different technologies, showing both the feasibility and portability of the work presented here.
Die Gewinnung und Bindung qualifizierter MINT-Mitarbeitender (Mathematik, Informatik, Naturwissenschaft und Technik) gehört zu den Herausforderungen des Personalmanagements, gerade in Bezug auf den weiblichen MINT-Nachwuchs. Spannend ist die Frage, ob Frauen Arbeitgebermerkmale anders gewichten als Männer und sich geschlechtsspezifische Präferenzen bei arbeitsplatzbezogenen Merkmalen auf den MINT-Kontext übertragen lassen. Eine empirische Untersuchung mit Studierenden technischer Studiengänge liefert Ansatzpunkte für die zielgruppenspezifische Gestaltung von Employer-Branding-Kampagnen und Rekrutierungsaktivitäten.
Resilienz gewinnt für produzierende Unternehmen immer mehr an Bedeutung. Es fehlen jedoch geeignete Maßzahlen, um ein Produktionssystem auf dessen Resilienzfähigkeit zu analysieren. Dieser Beitrag stellt Resilienzmessgrößen vor, welche es ermöglichen verschiedene Produktionssysteme zu vergleichen und zusätzlich Optimierungsmaßnahmen zu bewerten.
Condition monitoring supported with artificial intelligence, cloud computing, and industrial internet of things (IIoT) technologies increases the feasibility of predictive maintenance. However, the cost of traditional sensors, data acquisition systems, and the required information technology expert-knowledge challenge the industry. This paper presents a hybrid condition monitoring system (CMS) architecture consisting of a distributed, low-cost IIoT-sensor solution. The CMS uses micro-electro-mechanical system (MEMS) microphones for data acquisition, edge computing for signal preprocessing, and cloud computing, including artificial neural networks (ANN) for higher-level information processing. The system's feasibility is validated using a testbed for reciprocating linear-motion axes.
Machine failures’ consequences – a classification model considering ultra-efficiency criteria
(2023)
To strive for a sustainable production, maintenance has to evaluate possible machine failure consequences not just economically but also holistically. Approaches such as the ultra-efficiency factory consider energy, material, human/staff, emission, and organization as optimization dimensions. These ultra-efficiency dimensions can be considered for analyzing not only the respective machine failure but also the effects on the entire production system holistically. This paper presents an easy to use method, based on a questionnaire, for assessing the failure consequences of a machine malfunction in a production system considering the ultra-efficiency dimensions. The method was validated in a battery production.
Using predictive maintenance, more efficient processes can be implemented, leading to fewer maintenance costs and increased availability. The development of a predictive maintenance solution currently requires high efforts in time and capacity as well as often interdisciplinary cooperation. This paper presents a standardized model to describe a predictive maintenance use case. The description model is used to collect, present, and document the required information for the implementation of predictive maintenance use cases by and for different stakeholders. Based on this model, predictive maintenance solutions can be introduced more efficiently. The method is validated across departments in the automotive sector.
The increasing complexity and need for availability of automated guided vehicles (AGVs) pose challenges to companies, leading to a focus on new maintenance strategies. In this paper, a smart maintenance architecture based on a digital twin is presented to optimize the technical and economic effectiveness of AGV maintenance activities. To realize this, a literature review was conducted to identify the necessary requirements for Smart Maintenance and Digital Twins. The identified requirements were combined into modules and then integrated into an architecture. The architecture was evaluated on a real AGV on the battery as one of the critical components.
Dieses forschungsorientierte Buch enthält wichtige Beiträge zur Gestaltung der digitalen Transformation. Es umfasst die folgenden Hauptabschnitte in 20 Kapiteln:
- Digitale Transformation
- Digitales Geschäft
- Digitale Architektur
- Entscheidungshilfe
- Digitale Anwendungen
Es konzentriert sich auf digitale Architekturen für intelligente digitale Produkte und Dienstleistungen und ist eine wertvolle Ressource für Forscher, Doktoranden, Postgraduierte, Absolventen, Studenten, Akademiker und Praktiker, die sich für die digitale Transformation interessieren.
In diesem Kapitel wird eine Einführung in die sich abzeichnenden Trends bei der Gestaltung der digitalen Transformation gegeben, wobei der Schwerpunkt auf digitalen Produkten, intelligenten Diensten und damit verbundenen Systemen sowie auf Methoden, Modellen und Architekturen liegt. Das primäre Ziel dieses Buches ist es, einige der neuesten Forschungsergebnisse auf diesem Gebiet hervorzuheben. Wir stellen eine Reihe von Kurzbeschreibungen der im Buch enthaltenen Kapitel zur Verfügung.
Die digitale Transformation ist die heute vorherrschende geschäftliche Transformation, die einen starken Einfluss darauf hat, wie digitale Dienstleistungen und Produkte dienstleistungsdominant gestaltet werden. Eine beliebte zugrundeliegende Theorie der Wertschöpfung und des wirtschaftlichen Austauschs, die als dienstleistungsdominante Logik (S-D) bekannt ist, kann mit vielen erfolgreichen digitalen Geschäftsmodellen verbunden werden. Allerdings ist die S-D-Logik an sich abstrakt. Unternehmen können sie nicht ohne Weiteres als Instrument für die Innovation und Gestaltung von Geschäftsmodellen nutzen. Um dies zu ändern, wird eine umfassende Ideenfindungsmethode auf der Grundlage der S-D-Logik vorgeschlagen, die als service-dominantes Design (SDD) bezeichnet wird. SDD zielt darauf ab, Unternehmen beim Übergang zu einer service- und wertorientierten Perspektive zu unterstützen. Die Methode bietet eine vereinfachte Möglichkeit, den Ideenfindungsprozess auf der Grundlage von vier Modellkomponenten zu strukturieren. Jede Komponente besteht aus praktischen Implikationen, Hilfsfragen und Visualisierungstechniken, die aus einer Literaturrecherche, einer Anwendungsfallbewertung der digitalen Mobilität und einer Fokusgruppendiskussion abgeleitet wurden. SDD ist ein erster Schritt zu einem Toolset, das etablierte Unternehmen bei der Service- und Werteorientierung im Rahmen ihrer digitalen Transformation unterstützen kann.
Unternehmen sind derzeit dabei, ihre Strategie, ihre Prozesse und ihre Informationssysteme zu verändern, um ihren Digitalisierungsgrad zu erhöhen. Das Potenzial des Internets und verwandter digitaler Technologien wie Internet der Dinge, Services Computing, Cloud Computing, künstliche Intelligenz, Big Data mit Analysen, mobile Systeme, Kollaborationsnetzwerke und cyber-physikalische Systeme treibt neue Geschäftsmodelle an und ermöglicht sie. Die Digitalisierung führt zu einer tiefgreifenden Umwälzung bestehender Unternehmen, Technologien und Volkswirtschaften und fördert die Architektur digitaler Umgebungen mit vielen eher kleinen und verteilten Strukturen. Dies hat starke Auswirkungen auf neue Wertschöpfungsmöglichkeiten und die Gestaltung digitaler Dienste und Produkte, die durch die Nutzung einer service-dominanten Logik gesteuert werden. Das Hauptergebnis des Buchkapitels erweitert Methoden für integrale digitale Strategien um wertorientierte Modelle für digitale Produkte und Dienstleistungen, die im Rahmen eines multiperspektivischen digitalen Unternehmensarchitektur-Referenzmodells definiert werden.
Mobile monitoring of outpatients during cancer therapy becomes possible through technological advancements. This study leveraged a new remote patient monitoring app for in-between systemic therapy sessions. Patients’ evaluation showed that the handling is feasible. Clinical implementation must consider an adaptive development cycle for reliable operations.
This article proposes several modified quasi Z-source dc/dc boost converters. These can achieve soft-switching by using a clamp-switch network comprised of an active switch and a diode in parallel with a capacitor connected across one of the inductors of the Z-source network. In this way, ringing at the transistor switching node is mitigated, and the voltage at the turn-on of the transistor is reduced. Even a zero voltage switching (ZVS) of the main transistor is possible if the capacitor in the clamp-switch network is adequately chosen. The proposed circuit structure and operating mode are described and validated through simulations and measurements on a low-power prototype.
In dieser Arbeit werden Anforderungen an ein digitales Referenzmodell der Cell and Gene Therapy (CGT) Supply Chain mittels systematischer Literaturrecherche unter partieller Anwendung der Preferred-Reporting-Items-for-Systematic-Reviews-and-Meta-Analyses(PRISMA)-2020-Methode erarbeitet und erläutert. Die Ergebnisse der Literaturrecherche untermauern, dass die CGT Supply Chain standardisierte und automatisierte Prozesse benötigt, gewissen Transportanforderungen gerecht werden sowie eine lückenlose Rückverfolgbarkeit gewährleisten können muss. Die Anforderungen an das Referenzmodell lehnen sich z. T. an die Anforderungen des klassischen Supply-Chain-Operations-Reference(SCOR)-Modells an, bedürfen jedoch einer Veränderung und Weiterentwicklung unter Beachtung der Besonderheiten der CGT Supply Chain. Auf Basis eines Referenzmodells für die CGT Supply Chain, das die aus dieser Arbeit identifizierten Anforderungen beachtet, kann eine übergeordnete Managementplattform aufgebaut werden. Mit der digitalen Abbildung und Vernetzung aller Aktivitäten ist der Grundstein für die Integration in ein Enterprise-Resource-Planning(ERP)-System zum effektiven Data und Process Mining gelegt. Durch eine zunehmend bessere Datenqualität und -quantität entlang der Prozesse der CGT Supply Chain lassen sich verstärkt Informationen über die Prozesse selbst generieren, aus denen weitere Verbesserungsansätze hervorgehen. Eine CGT-Managementplattform bildet demnach die Grundlage für alle Prozesse innerhalb der CGT Supply Chain für einen kontinuierlichen Verbesserungsprozess.
Sleep is extremely important for physical and mental health. Although polysomnography is an established approach in sleep analysis, it is quite intrusive and expensive. Consequently, developing a non-invasive and non-intrusive home sleep monitoring system with minimal influence on patients, that can reliably and accurately measure cardiorespiratory parameters, is of great interest. The aim of this study is to validate a non-invasive and unobtrusive cardiorespiratory parameter monitoring system based on an accelerometer sensor. This system includes a special holder to install the system under the bed mattress. The additional aim is to determine the optimum relative system position (in relation to the subject) at which the most accurate and precise values of measured parameters could be achieved. The data were collected from 23 subjects (13 males and 10 females). The obtained ballistocardiogram signal was sequentially processed using a sixth-order Butterworth bandpass filter and a moving average filter. As a result, an average error (compared to reference values) of 2.24 beats per minute for heart rate and 1.52 breaths per minute for respiratory rate was achieved, regardless of the subject’s sleep position. For males and females, the errors were 2.28 bpm and 2.19 bpm for heart rate and 1.41 rpm and 1.30 rpm for respiratory rate. We determined that placing the sensor and system at chest level is the preferred configuration for cardiorespiratory measurement. Further studies of the system’s performance in larger groups of subjects are required, despite the promising results of the current tests in healthy subjects.
Herein, biochar from biomass residues is demonstrated as active materials for the catalytic cracking of waste motor oil into diesel-like fuels. Above all, alkali-treated rice husk biochar showed great activity with a 250% increase in the kinetic constant compared to the thermal cracking. It also showed better activity than synthetic materials, as previously reported. Moreover, much lower activation energy (185.77 to 293.48 kJ/mol) for the cracking process was also obtained. According to materials characterization, the catalytic activity was more related to the nature of the biochar’s surface than its specific surface area. Finally, liquid products complied with all the physical properties defined by international standards for diesel-like fuels, with the presence of hydrocarbons chains between C10 - C27 similar to the ones obtained in commercial diesel.
Vertragsstrafen und Schadenspauschalen wegen verspäteter Lieferung in CISG-Einkaufsbedingungen
(2023)
Der Käufer will in seinen Einkaufsbedingungen die Folgen verspäteter Lieferungen regeln. Er will sicherstellen, dass der Verkäufer die Nachteile, die durch die Verspätung entstehen, voll ausgleichen muss. Das deutsche AGB-Recht setzt hier dem Käufer rechtliche Grenzen. Sie gelten grundsätzlich auch, wenn UN-Kaufrecht Anwendung findet und Rechtswahl oder Kollisionsrecht des Forumstaates auf deutsches Recht verweisen. Die Wirksamkeit der Klauseln hängt dann von den Wertungen ab, die dem UN-Kaufrecht zugrunde liegen. Bei der Gestaltung von Einkaufsbedingungen hat das Vorteile: Das UN-Kaufrecht schafft Freiräume, die man nicht hat, wenn nur das BGB gilt.
Einkaufsbedingungen weichen mitunter von der gesetzlichen Regelung der Folgen der verspäteten Lieferung ab: Hier finden sich oft Klauseln, die fixe Summen vorsehen. Mit ihnen will der Käufer sicherstellen, mindestens diese Summe vom Verkäufer bei verspäteter Lieferung zu erhalten. Das ist aber nicht das einzige Ziel, das der Käufer mit den fixen Summen verfolgt. Auch will er, dass der Verkäufer ihm Schäden ersetzt, die über diese fixe Summe hinausgehen. Darüber hinaus will der Käufer sich und sein Unternehmen nicht mit zusätzlichen Formalien belasten, etwa mit einer Pflicht, sich bei Annahme verspäteter Lieferungen weitergehende Rechte vorbehalten zu müssen. Beiden fixen Summen, die der Käufer wählen kann, ist zwischen Schadenspauschale und Vertragsstrafe zu unterscheiden. Die Vertragsstrafe soll als „Druckmittel“ die rechtzeitige Belieferung des Käufers sicherstellen, die Schadenspauschale soll dem Käufer helfen, seinen Schaden einfacher gerichtlich durchsetzen zu können. Gilt UN-Kaufrecht, ist die Vereinbarung von Vertragsstrafe oder Schadenspauschale zulässig. Das kann auch durch Einkaufsbedingungen geschehen.
In 2015, the United Nations adopted the Sustainable Development Goals (SDGs), a collection of 17 global objectives to promote economic, social and ecological development in all parts of the world. While the academic discussion on the contribution of companies to the Sustainable Development Goals has recently gained momentum, the role of business-to-business (B2B) partnerships in reaching the SDGs is underexplored, particularly when it comes to North-South relationships. With our research, we aim to fill this gap in the literature by investigating sales partnerships between German manufacturers and their distributors in African markets. Based on a qualitative analysis of 28 interviews with managers of German and African companies, we show that long-term partnerships and job creation, technology transfer, training as well as high standards are significant contributions of companies to achieve the SDGs. While several SDGs such as goals 4,6,13,16 and 17 are addressed by B2B partnership, we also discuss approaches on how the firms’ engagement could be further leveraged and expanded.
Naturfasern dienen der Menschheit seit Urzeiten als wichtiger Rohstoff für viele Gegenstände des täglichen Lebens, sei es als Kleidung, als technische Textilprodukte oder, im Falle von Cellulosefasern, als Ballaststoffe bei unserer Ernährung. Waren die allerersten Gebrauchstextilien unserer Vorfahren noch hauptsächlich tierischen Ursprungs in Form von Fellen und Pelzen, so wurden zunehmend die Pflanzenfasern als Ressource für vielfältige Anwendungen entdeckt. Dem Beispiel der Natur folgend, fanden die unterschiedlichen Faserarten Anwendung entsprechend ihres natürlichen Bestimmungszwecks bzw. entsprechend ihrer morphologischen und technologischen Eigenschaften. So wurde und wird z.B. Wolle aufgrund ihrer flexiblen, isolierenden und wärmenden Eigenschaften hauptsächlich als Kleidung und als Kälteschutz eingesetzt, während sich die steifen, glatten und festen Bastfasern wie Flachs oder Hanf, sich eher als Seile, Netze oder auch als Bogensehnen eigneten.
Non-fungible tokens (NFTs) are unique digital assets that have recently gained significant popularity, particularly in the digital art sector. The success of NFTs and other blockchain-based innovations depends on their ac-acceptance and use by consumers. This study aims to understand the impact of moral values on the acceptance of NFTs. Based on a quantitative survey with over 800 complete responses, the analysis shows that moral aspects of NFTs are indeed important for potential users. However, there is an attitude-behavior gap, as the positive impact of moral values on the intention to use NFTs is not reflected in the actual current usage of NFTs by the respondents. This study contributes to knowledge by providing new empirical data on the acceptance of NFTs and highlighting the role of moral values on the acceptance decision.
The pH value of the human skin is not in the neutral range but is slightly acidic with values of – depending on the body part – 3.5 to 6. This provides a suitable habitat for the commensal skin floral but has a killing effect on some pathogenic micro-organisms and an inactivating effect on some viruses. This protective acid mantle of the skin thus represents a first external protective layer against infestation by pathogens. An appropriate surface pH on textiles can help to minimize the transmission of pathogens through the clothing of healthcare workers while at the same time not exerting a negative influence on the skin’s own flora. In addition, the colonization of e.g. bed linen by pathogenic microorganisms can be reduced. This can also have a positive influence on bacteria-associated odor formation on functional clothing.
Die Digitalisierung, der ständige technologische Fortschritt und immer kürzere Produktlebenszyklen stellen Unternehmen derzeit vor große Herausforderungen. Um am Markt erfolgreich zu sein, müssen Geschäftsmodelle häufiger und schneller als früher an veränderte Marktbedingungen angepasst werden. Schnelle Anpassungsfähigkeit, auch Agilität genannt, ist in der heutigen Zeit ein entscheidender Wettbewerbsfaktor. Aufgrund des ständig wachsenden IT-Anteils von Produkten und der Tatsache, dass diese mit Hilfe von IT hergestellt werden, hat die Änderung des Geschäftsmodells große Auswirkungen auf die Unternehmensarchitektur (EA). Die Entwicklung von EAs ist jedoch eine sehr komplexe Aufgabe, da viele Beteiligte mit gegensätzlichen Interessen in den Entscheidungsprozess eingebunden sind. Daher ist ein hohes Maß an Zusammenarbeit erforderlich. Um Unternehmen bei der Entwicklung ihrer EA zu unterstützen, wird in diesem Artikel eine neuartige integrative Methode vorgestellt, die die Interessen der Stakeholder systematisch in die Entscheidungsfindung einbezieht. Durch die Anwendung der Methode wird die Zusammenarbeit zwischen den beteiligten Interessengruppen verbessert, indem Berührungspunkte zwischen ihnen identifiziert werden. Darüber hinaus machen die standardisierten Aktivitäten die Entscheidungsfindung transparenter und vergleichbarer, ohne die Kreativität einzuschränken.
The volume includes papers presented at the International KES Conference on Human Centred Intelligent Systems 2023 (KES HCIS 2023), held in Rome, Italy on June 14–16, 2023. This book highlights new trends and challenges in intelligent systems, which play an important part in the digital transformation of many areas of science and practice. It includes papers offering a deeper understanding of the human-centred perspective on artificial intelligence, of intelligent value co-creation, ethics, value-oriented digital models, transparency, and intelligent digital architectures and engineering to support digital services and intelligent systems, the transformation of structures in digital businesses and intelligent systems based on human practices, as well as the study of interaction and the co-adaptation of humans and systems.
Current advances in Artificial Intelligence (AI) combined with other digitalization efforts are changing the role of technology in service ecosystems. Human-centered intelligent systems and services are the target of many current digitalization efforts and part of a massive digital transformation based on digital technologies. Artificial intelligence, in particular, is having a powerful impact on new opportunities for shared value creation and the development of smart service ecosystems. Motivated by experiences and observations from digitalization projects, this paper presents new methodological experiences from academia and practice on a joint view of digital strategy and architecture of intelligent service ecosystems and explores the impact of digitalization based on real case study results. Digital enterprise architecture models serve as an integral representation of business, information, and technology perspectives of intelligent service-based enterprise systems to support management and development. This paper focuses on the novel aspect of closely aligned digital strategy and architecture models for intelligent service ecosystems and highlights the fundamental business mechanism of AI-based value creation, the corresponding digital architecture, and management models. We present key strategy-oriented architecture model perspectives for intelligent systems.
In today’s education, healthcare, and manufacturing sectors, organizations and information societies are discussing new enhancements to corporate structure and process efficiency using digital platforms. These enhancements can be achieved using digital tools. Industry 5.0 and Society 5.0 give several potentials for businesses to enhance the adaptability and efficacy of their industrial processes, paving the door for developing new business models facilitated by digital platforms. Society 5.0 can contribute to a super-intelligent society that includes the healthcare industry. In the past decade, the Internet of Things, Big Data Analytics, Neural Networks, Deep Learning, and Artificial Intelligence (AI) have revolutionized our approach to various job sectors, from manufacturing and finance to consumer products. AI is developing quickly and efficiently. We have heard of the latest artificial intelligence chatbot, ChatGPT. OpenAI created this, which has taken the internet by storm. We tested the effectiveness of a considerable language model referred to as ChatGPT on four critical questions concerning “Society 5.0”, “Healthcare 5.0”, “Industry,” and “Future Education” from the perspectives of Age 5.0.
Enterprises and societies currently face essential challenges, and digital transformation can contribute to their resolution. Enterprise architecture (EA) is useful for promoting digital transformation in global companies and information societies covering ecosystem partners. The advancement of new business models can be promoted with digital platforms and architectures for Industry 4.0 and Society 5.0. Therefore, products from the sector of healthcare, manufacturing and energy, etc. can increase in value. The adaptive integrated digital architecture framework (AIDAF) for Industry 4.0 and the design thinking approach is expected to promote and implement the digital platforms and digital products for healthcare, manufacturing and energy communities more efficiently. In this paper, we propose various cases of digital transformation where digital platforms and products are designed and evaluated for digital IT, digital manufacturing and digital healthcare with Industry 4.0 and Society 5.0. The vision of AIDAF applications to perform digital transformation in global companies is explained and referenced, extended toward the digitalized ecosystems such as Society 5.0 and Industry 4.0.