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The implementation of human resource (HR) policies often proves troublesome due to the appearance, and stubborn persistence, of gaps in the process. Human resource management (HRM) scholars problematise these gaps and advocate tight implementation to reduce gaps and to ensure the desired impact of policies on organisational performance. Drawing on organisational institutionalism, we contend that gaps in implementing HR policies can actually be productive, as they secure organisational legitimacy, and thus enable organisations to operate viably within several institutional environments. We suggest that different approaches to implementation are needed, some of them premised on accepting sustained implementation gaps. We introduce minimum and moderate implementation approaches, rooted in the notion of decoupling, to complement approaches aimed at tight implementation. Our aim is to support the further development of research based on a richer interpretation of HRM implementation challenges and choices they present for HR managers.
Current clinical practice is often unable to identify the causes of conductive hearing loss in the middle ear with sufficient certainty without exploratory surgery. Besides the large uncertainties due to interindividual variances, only partially understood cause–effect principles are a major reason for the hesitant use of objective methods such as wideband tympanometry in diagnosis, despite their high sensitivity to pathological changes. For a better understanding of objective metrics of the middle ear, this study presents a model that can be used to reproduce characteristic changes in metrics of the middle ear by altering local physical model parameters linked to the anatomical causes of a pathology. A finite-element model is, therefore, fitted with an adaptive parameter identification algorithm to results of a temporal bone study with stepwise and systematically prepared pathologies. The fitted model is able to reproduce well the measured quantities reflectance, impedance, umbo and stapes transfer function for normal ears and ears with otosclerosis, malleus fixation, and disarticulation. In addition to a good representation of the characteristic influences of the pathologies in the measured quantities, a clear assignment of identified model parameters and pathologies consistent with previous studies is achieved. The identification results highlight the importance of the local stiffness and damping values in the middle ear for correct mapping of pathological characteristics and address the challenges of limited measurement data and wide parameter ranges from the literature. The great sensitivity of the model with respect to pathologies indicates a high potential for application in model-based diagnosis.
Global, competitive markets which are characterised by mass customisation and rapidly changing customer requirements force major changes in production styles and the configuration of manufacturing systems. As a result, factories may need to be regularly adapted and optimised to meet short-term requirements. One way to optimise the production process is the adaptation of the plant layout to the current or expected order situation. To determine whether a layout change is reasonable, a model of the current layout is needed. It is used to perform simulations and in the case of a layout change it serves as a basis for the reconfiguration process. To aid the selection of possible measurement systems, a requirements analysis was done to identify the important parameters for the creation of a digital shadow of a plant layout. Based on these parameters, a method is proposed for defining limit values and specifying exclusion criteria. The paper thus contributes to the development and application of systems that enable an automatic synchronisation of the real layout with the digital layout.
Higher education institutions (HEIs) rely heavily on information technology (IT) to create innovations. Therefore, IT governance (ITG) is essential for education activities, particularly during the ongoing COVID-19 pandemic. However, the traditional concept of ITG is not fully equipped to deal with the current changes occurring in the digital age. Today's ITG requires an agile approach that can respond to disruptions in the HEI environment. Consequently, universities increasingly need to adopt agile strategies to ensure superior performance. This research proposes a conceptualization comprising three agile dimensions within the ITG construct: structures, processes, and relational mechanisms. An extensive qualitative evaluation of industry uncovered 46 agile governance mechanisms. Moreover, 16 professors rated these elements to assess agile ITG in their HEIs to determine those most effective for HEIs. This led to the identification of four structure elements, seven processes, and seven relational mechanisms.
We propose a novel technique to compensate the effects of R-C / gm-C time-constant (TC) errors due to process variation in continuous-time delta-sigma modulators. Local TC error compensation factors are shifted around in the modulator loop to positions where they can be implemented efficiently with tunable circuit structures, such as current-steering digital-to-analog converters (DAC). This approach constitutes an alternative or supplement to existing compensation techniques, including capacitor or gm tuning. We apply the proposed technique to a third-order, single-bit, low-pass continuous-time delta-sigma modulator in cascaded integrator feedback structure. A feedback path tuning scheme is derived analytically and confirmed numerically using behavioral simulations. The modulator circuit was implemented in a 0.35-μm CMOS process using an active feedback coefficient tuning structure based on current-steering DACs. Post-layout simulations show that with this tuning structure, constant performance and stable operation can be obtained over a wide range of TC variation.
The scoring of sleep stages is an essential part of sleep studies. The main objective of this research is to provide an algorithm for the automatic classification of sleep stages using signals that may be obtained in a non-obtrusive way. After reviewing the relevant research, the authors selected a multinomial logistic regression as the basis for their approach. Several parameters were derived from movement and breathing signals, and their combinations were investigated to develop an accurate and stable algorithm. The algorithm was implemented to produce successful results: the accuracy of the recognition of Wake/NREM/REM stages is equal to 73%, with Cohen's kappa of 0.44 for the analyzed 19324 sleep epochs of 30 seconds each. This approach has the advantage of using the only movement and breathing signals, which can be recorded with less effort than heart or brainwave signals, and requiring only four derived parameters for the calculations. Therefore, the new system is a significant improvement for non-obtrusive sleep stage identification compared to existing approaches.
Säureschutzmantel - Ausrüstung zum Schutz gegen mikrobiellen Befall - (DTNW Mitteilung Nr. 129)
(2022)
Ziel des Forschungsvorhabens war es, den Effekt des Säureschutzmantels der menschlichen Haut auf der textilen Oberfläche unter der Verwendung von Säurekatalyten nachzuahmen, um so neuartige, antibakterielle Textilien zu entwickeln. Hierzu sollten für die Textilindustrie wässrige Ausrüstungen entwickelt werden, die über konventionelle Veredlungstechniken wie das Foulardieren appliziert werden können. Die Aktivität der Ausrüstung sollte im feuchten Millieu gegeben sein, um einen Effekt beim Tragen von z.B. Funktionskleidung oder Arbeitskleidung im medizinischen Bereich zu gewährleisten.
Für die Erfüllung der Projektziele wurden verschiedene kommerzielle Polyoxometallate verwendet. Zudem wurden Polyoxometallate synthetisiert und funktionalisiert. Diese führen im wässrigen Millieu eine saure Katalyse durch und kommen als industrielle Katalysatoren an Membranen gebunden zum Einsatz. Ein Aktivitätsscreening geeigneter Kandidaten zeigte, dass eine wässrige Applikation möglich ist und zu einer antibakteriellen Aktivität der ausgerüsteten Textilien führt.
Die Polyoxometallate konnten durch das Sol-Gel-Verfahren mittels Tetraethoxysilan durch Foulardierverfahren im Labormaßstab an verschiedenen Textilien immobilisiert werden. Eine Hochskalierung auf den Technikumsmaßstab gelang ebenfalls. Das Aktivitätsscreening der Ausrüstungen zeigte, dass ein saurer Oberflächen-pH-Wert von ≤ 4 durch die entwickelte Ausrüstung möglich ist und zu einem antibakteriellen Effekt führt. Die Abrasionsbeständigkeit war gegeben. Nach Waschversuchen verloren die Ausrüstungen zum Teil ihren antibakteriellen Effekt.
Insgesamt ergab sich ein Einblick in den Nutzen von Polyoxometallaten als katalytisch aktive Substanz, die zur Ausrüstung von Textilien geeignet ist. Da die in diesem Forschungsvorhaben synthetisierten Polyoxometallate keine genotoxische und mutagene Aktivität aufweisen, können die KMU des textilveredelnden Wirtschaftszweigs eine neue Art der antibakteriellen Ausrüstung anwenden. Um eine Waschstabile Ausrüstung zu erzielen, müssen die Funktionalisierungen und darüber die Bindung der Polyoxometallate an die Ausrüstungsmatrix jedoch weiterentwickelt werden.
Die Ziele des Forschungsvorhabens wurden erreicht.
Due to its availability and minimal invasive harvesting human adipose tissue-derived extracellular matrix (dECM) is often used as a biomaterial in various tissue engineering and healthcare applications. Next to dECM, cell-derived ECM (cdECM) can be generated by and isolated from in vitro cultured cells. So far both types of ECM were investigated extensively toward their application as (bio)material in tissue engineering and healthcare. However, a systematic characterization and comparison of soft tissue dECM and cdECM is still missing. In this study, we characterized dECM from human adipose tissue, as well as cdECM from human adipose-derived stem cells, toward their molecular composition, structural characteristics, and biological purity. The dECM was found to exhibit higher levels of collagens and lower levels of sulfated glycosaminoglycans compared with cdECMs. Structural characteristics revealed an immature state of the fibrous part of cdECM samples. By the identified differences, we aim to support researchers in the selection of a suitable ECM-based biomaterial for their specific application and the interpretation of obtained results.
For collision and obstacle avoidance as well as trajectory planning, robots usually generate and use a simple 2D costmap without any semantic information about the detected obstacles. Thus a robot’s path planning will simply adhere to an arbitrarily large safety margin around obstacles. A more optimal approach is to adjust this safety margin according to the class of an obstacle. For class prediction, an image processing convolutional neural network can be trained. One of the problems in the development and training of any neural network is the creation of a training dataset. The first part of this work describes methods and free open source software, allowing a fast generation of annotated datasets. Our pipeline can be applied to various objects and environment settings and is extremely easy to use to anyone for synthesising training data from 3D source data. We create a fully synthetic industrial environment dataset with 10 k physically-based rendered images and annotations. Our da taset and sources are publicly available at https://github.com/LJMP/synthetic-industrial-dataset. Subsequently, we train a convolutional neural network with our dataset for costmap safety class prediction. We analyse different class combinations and show that learning the safety classes end-to-end directly with a small dataset, instead of using a class lookup table, improves the quantity and precision of the predictions.
Allyls
(2022)
This chapter addresses the importance and usage of the commercially low-volume thermoset plastics group known as allyls. The three significant subelements of this group are poly(diallylphthalates), poly(diallylisophthalates), and poly(allyldiglycol carbonate). Chemistry, processing, and properties are also described. Allyl polymers are synthesized by radical polymerizations of allyl monomers that usually do not produce high-molecular-mass macromolecules. Therefore only a few specific monomers can produce thermosetting materials. Diallyldiglycolcarbonate (CR-39) and diallylphthalates are the most significant examples that have considerably improved our everyday life.
Unsaturated polyester resins (UPR) and vinyl ester resins (VER) are among the most commercially important thermosetting matrix materials for composites. Although comparatively low cost, their technological performance is suitable for a wide range of applications, such as fiber-reinforced plastics, artificial marble or onyx, polymer concrete, or gel coats. The main areas of UPR consumption include the wind energy, marine, pipe and tank, transportation, and construction industries.
This chapter discusses basic UPR and VER chemistry and technology of manufacturing, and consequent applications. Some important properties and performance characteristics are discussed, such as shrinkage behavior, flame retardance, and property modification by nanoparticles. Also briefly introduced and described are the practical aspects of UPR and VER processing, with special emphasis on the most widely used technological approaches, such as hand and spray layup, resin infusion, resin transfer molding, sheet and bulk molding, pultrusion, winding, and centrifugal casting.
The blockchain technology represents a decentralized database that stores information securely in immutable data blocks. Regarding supply chain management, these characteristics offer potentials in increasing supply chain transparency, visibility, automation, and efficiency. In this context, first token-based mapping approaches exist to transfer certain manufacturing processes to the blockchain, such as the creation or assembly of parts as well as their transfer of ownership. However, the decentralized and immutable structure of blockchain technology also creates challenges when applying these token-based approaches to dynamic manufacturing processes. As a first step, this paper investigates existing mapping approaches and exemplifies weaknesses regarding their suitability for products with changeable configurations. Secondly, a concept is proposed to overcome these weaknesses by introducing logically coupled tokens embedded into a flexible smart contract structure. Finally, a concept for a token-based architecture is introduced to map manufacturing processes of products with changeable configurations.
This study empirically analyzes and compares return data from developed and emerging market data based on the Fama French five-factor model and compares it to previous results from the Fama French three-factor model by Kostin, Runge and Adams (2021). It researches whether the addition of the profitability and investment pattern factors show superior results in the assessment of emerging markets during the COVID-19 pandemic compared to developed markets. We use panel data covering eight indices of developed and emerging countries as well as a selection of eight companies from these markets, covering a period from 2000 to 2020. Our findings suggest that emerging markets do not generally outperform developed markets. The results underscore the need to reconsider the assumption that adding more factors to regression models automatically yields results that are more reliable. Our study contributes to the extant literature by broadening this research area. It is the first study to compare the performance of the Fama French three-factor model and the Fama French five-factor model in the cost of equity calculation for developed and emerging countries during the COVID-19 pandemic and other crisis events of the past two decades.
Gewinn, Profitabilität und Wachstum eines Unternehmens sind untrennbar mit dem Arbeitseinsatz und der Mitarbeiterperformance verbunden (Birri, 2014; Bligh et al., 2006). Arbeitseinsatz und Performance wiederum erwachsen maßgeblich aus den grundlegenden intrinsischen und extrinsischen Motivationstreibern. Also müssen Unternehmen zur Sicherung ihres Erfolgs mit geeigneten Werkzeugen gezielt auf diese Treiber einwirken. Ein zentrales Werkzeug hierfür sind die Vergütungssysteme der Unternehmen.
The world population is growing and alternative ways of satisfying the increasing demand for meat are being explored, such as using animal cells for the fabrication of cultured meat. Edible biomaterials are required as supporting structures. Hence, we chose agarose, gellan and a xanthan-locust bean gum blend (XLB) as support materials with pea and soy protein additives and analyzed them regarding material properties and biocompatibility. We successfully built stable hydrogels containing up to 1% pea or soy protein. Higher amounts of protein resulted in poor handling properties and unstable gels. The gelation temperature range for agarose and gellan blends is between 23–30 °C, but for XLB blends it is above 55 °C. A change in viscosity and a decrease in the swelling behavior was observed in the polysaccharide-protein gels compared to the pure polysaccharide gels. None of the leachates of the investigated materials had cytotoxic effects on the myoblast cell line C2C12. All polysaccharide-protein blends evaluated turned out as potential candidates for cultured meat. For cell-laden gels, the gellan blends were the most suitable in terms of processing and uniform distribution of cells, followed by agarose blends, whereas no stable cell-laden gels could be formed with XLB blends.
Up to now biorefinery concepts can hardly compete with the conventional production of fossil-based chemicals. On one hand, conventional chemical production has been optimised over many decades in terms of energy, yield and costs. Biorefineries, on the other hand, do not have the benefit of long-term experience and therefore have a huge potential for optimisation. This study deals with the economic evaluation of a newly developed biorefinery concept based on superheated steam (SHS) torrefaction of biomass residues with recovery of valuable platform chemicals. Two variants of the biorefinery were economically investigated. One variant supplies various platform chemicals and torrefied biomass. The second variant supplies thermal energy for external consumers in addition to platform chemicals. The results show that both variants can be operated profitably if the focus of the platform chemicals produced is on high quality and thus on the higher-priced segment. The economic analysis gives clear indications of the most important financial influencing parameters. The economic impact of integration into existing industrial structures is positive. With the analysis, a viable business model can be developed. Based on the results of the present study, an open-innovation platform is recommended for the further development and commercialisation of the novel biorefinery.
The food system represents a key industry for Europe and Germany in particular. However, it is also the single most significant contributor to climate and environmental change. A food system transformation is necessary to overcome the system’s major and constantly increasing challenges in the upcoming decades. One possible facilitator for this transformation are radical and disruptive innovations that start-ups develop. There are many challenges for start-ups in general and food start-ups in particular. Various support opportunities and resources are crucial to ensure the success of food start-ups. One aim of this study is to identify how the success of start-ups in the food system can be supported and further strengthened by actors in the innovation ecosystem in Germany. There is still room for improvement and collaboration toward a thriving innovation ecosystem. A successful innovation ecosystem is characterised by a well-organised, collaborative, and supportive environment with a vivid exchange between the members in the ecosystem. The interviewees confirmed this, and although the different actors are already cooperating, there is still room for improvement. The most common recommendation for improving cooperation is learning from other countries and bringing the best to Germany.
Commercially available homogenized cow- and plant-based milks were investigated by optical spectroscopy in the range of 400–1360 nm. Absorbance spectra, the effective scattering coefficient μs′, and the spectral absorption coefficient μa were recorded for 23 milk varieties and analyzed by multivariate data analysis. Cow- and plant-based milks were compared and discriminated using principal component analysis combined with a quadratic discriminant analysis. Furthermore, it was possible to discriminate the origin of plant-based milk by μa and the fat content in cow-based milk by μs′. Partial least squares regression models were developed to determine the fat content in cow-based milk. The model for μs′ proved to be the most efficient for this task with R2 = 0.98 and RMSEP = 0.19 g/100 mL for the external validation. Thus, optical spectroscopy together with multivariate data analysis is suitable for routine laboratory analysis or quality monitoring in the dairy production.
Public transport maps are typically designed in a way to support route finding tasks for passengers, while they also provide an overview about stations, metro lines, and city-specific attractions. Most of those maps are designed as a static representation, maybe placed in a metro station or printed in a travel guide. In this paper, we describe a dynamic, interactive public transport map visualization enhanced by additional views for the dynamic passenger data on different levels of temporal granularity. Moreover, we also allow extra statistical information in form of density plots, calendar-based visualizations, and line graphs. All this information is linked to the contextual metro map to give a viewer insights into the relations between time points and typical routes taken by the passengers. We also integrated a graph-based view on user-selected routes, a way to interactively compare those routes, an attribute- and property-driven automatic computation of specific routes for one map as well as for all available maps in our repertoire, and finally, also the most important sights in each city are included as extra information to include in a user-selected route. We illustrate the usefulness of our interactive visualization and map navigation system by applying it to the railway system of Hamburg in Germany while also taking into account the extra passenger data. As another indication for the usefulness of the interactively enhanced metro maps we conducted a controlled user experiment with 20 participants.
The paradigmatic shift of production systems towards Cyber-Physical Production Systems (CPPSs) requires the development of flexible and decentralized approaches. In this way, such systems enable manufacturers to respond quickly and accurately to changing requirements. However, domain-specific applications require the use of suitable conceptualizations. The issue at hand, when using various conceptualizations is the interoperability of different ontologies. To achieve flexibility and adaptability in CPPSs though requires overcoming interoperability issues within CPPSs. This paper presents an approach to increase flexibility and adaptability in CPPSs while addressing the interoperability issue. In this work, OWL ontologies conceptualize domain knowledge. The Intelligent Manufacturing Knowledge Ontology Repository (IMKOR) connects the domain knowledge in different ontologies. Testing if adaptions in one ontology within the IMKOR provide knowledge to the whole IMKOR. The tests showed, positive results and the repository makes the knowledge available to the whole CPPS. Furthermore, an increase in flexibility and adaptability was noticed.
Purpose
The purpose of this study is to examine private households’ preferences for service bundles in the German energy market.
Design/methodology/approach
This investigation is based on survey data collected from 3,663 customers of seven mainly municipal energy suppliers in the German energy market. The data set was analyzed via a binary logistic regression model to identify the most prospective customers and their preferences regarding bundles of energy services.
Findings
The results indicate that potential adopters of energy-related service bundles have greater prior knowledge about service bundles; place higher importance on simplified handling, flat rates and long price guarantees; prefer to purchase a service bundle from an energy supplier; live in urban areas and have a gas tariff; are both less likely to have a green electricity tariff and to support the German energy transition; have a greater intention to purchase a smart home product; are less likely to already be prosumers; and prefer customer centers and social media as communication channels with energy providers.
Practical implications
This paper offers several implications for decision-makers in developing marketing strategies for bundled offerings in a highly competitive energy market.
Originality/value
This paper contributes to the sparse research on service bundles in the energy sector, despite the growing interest of energy suppliers and consumers in this topic. It expands the research focusing on the telecommunications sector.
A new planar compact antenna composed of two crossed Cornu spirals is presented. Each Cornu spiral is fed from the center of the linearly part of the curvature between the two spirals, which builds the clothoid. Sequential rotation is applied using a sequential phase network to obtain circular polarization and increase the effective bandwidth. Signal integrity issues have been addressed and designed to ensure high quality of signal propagation. As a result, the antenna shows good radiation characteristics in the bandwidth of interest. Compared to antennas of the same size in the literature, it is broadband and of high gain. Although the proposed antenna has been designed for K- and Ka-band operations, it can also be developed for lower and upper frequencies because of the linearity of the Maxwell equations.
Evaluation of human-robot order picking systems considering the evolution of object detection
(2022)
The automation of intralogistic processes is a major trend, but order picking, one of the core and most cost-intensive tasks in this field, remains mostly manual due to the flexibility required during picking. Reacting to its hard physical and ergonomic strain, the automation of this process is however highly relevant. Robotic picking system would enable the automation of this process from a technical point of view, but the necessity for the system to evolve in time, due to dynamics of logistic environments, faces operations with new challenges that are hardly treated in literature. This unknown scares potential investors, hindering the application of technically feasible solutions. In this paper, a model for the evaluation of the additional cost of training of automated systems during operations is presented, that also considers the savings enabled by the system after its evolution. The proposed approach, that considers different parameters such as capacity, ergonomics and cost, is validated with a case study and discussed.
According to several surveys and statistics, the great majority of companies previously not accustomed to automation are piloting solutions to automate business processes. Those accustomed to automation also attempt to introduce more of it, focusing on automation-unfriendly processes that remained manual. However, when the decision on what and whether to automate is not trivial for evident reasons, even industry leaders may get stuck on an overwhelming question: where to begin automating? The question remains too often unanswered as state-of-the-art methods fail to consider the whole picture. This paper introduces a holistic approach to the decision-making for investments in automation. The method supports the iterative analysis and evaluation of operative processes, providing tools for a quantitative approach to the decision-making. Thanks to the method, a large pool of processes can be first considered and then filtered out in order to select the one that yields the best value for the automation in the specific context. After introducing the method, a case study is reported for validation before the discussion.
Compared to the automotive sector, where automation is the rule, in many other less standardized sectors automation is still the exception. This could soon hurt the productivity of industrialized countries, where the unemployment is low and the population is aging. Phenomena like the recent downfall in productivity, due to lockdowns and social distancing for prevention of health hazards during the COVID19 pandemic, only add to the problem. For these reasons, the relevance, motivation and intention for more automation in less standardized sectors has probably never been higher. However, available statistics say that providers and users of technologies struggle to bring more automation into action in automation-unfriendly sectors. In this paper, we present a decision support method for investment in automation that tackles the problem: the STIC analysis. The method takes a holistic and quantitative approach tying together technological, context-related and economic input parameters and synthetizing them in a final economic indicator. Thanks to the modelling of such parameters, it is possible to gain sensibility on the technological and/or process adjustments that would have the highest impact on the efficiency of the automation, thereby delivering value for both technology users and technology providers.
A closed-loop control for a cooperative innovation culture in interorganizational R&D projects
(2022)
Since project managers only have a limited authority in interorganizational R&D projects a cooperative innovation culture is essential for team cohesion and thus for achieving project scope in time and cost. For its development different factors depending on underlying values are essential. These factors must be learned iteratively by the project members so that they are living the values of a cooperative innovation culture. Hence, this paper raises the following research question: “How to control living the values of a cooperative innovation culture in interorganizational R&D projects?” To answer this question, a closed-loop control for a cooperative innovation culture is developed. The developed closed-loop control system includes several different functional units which show essential roles and several different variables which show what to consider and design in the control system. In addition, the developed closed-loop control system is generalized for other types of projects such as intraorganizational projects.
Morphometry and stiffness of red blood cells - signatures of neurodegenerative diseases and aging
(2022)
Human red blood cells (RBCs) are unique cells with the remarkable ability to deform, which is crucial for their oxygen transport function, and which can be significantly altered under pathophysiological conditions. Here we performed ultrastructural analysis of RBCs as a peripheral cell model, looking for specific signatures of the neurodegenerative pathologies (NDDs) - Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease (AD), utilizing atomic force (AFM) and conventional optical (OM) microscopy. We found significant differences in the morphology and stiffness of RBCs isolated from patients with the selected NDDs and those from healthy individuals. Neurodegenerative pathologies’ RBCs are characterized by a reduced abundance of biconcave discoid shape, lower surface roughness and a higher Young’s modulus, compared to healthy cells. Although reduced, the biconcave is still the predominant shape in ALS and AD cells, while the morphology of PD is dominated by crenate cells. The features of RBCs underwent a marked aging-induced transformation, which followed different aging pathways for NDDs and normal healthy states. It was found that the diameter, height and volume of the different cell shape types have different values for NDDs and healthy cells. Common and specific morphological signatures of the NDDs were identified.
Adoption of artificial intelligence (AI) has risen sharply in recent years but many firms are not successful in realising the expected benefits or even terminate projects before completion. While there are a number of previous studies that highlight challenges in AI projects, critical factors that lead to project failure are mostly unknown. The aim of this study is therefore to identify distinct factors that are critical for failure of AI projects. To address this, interviews with experts in the field of AI from different industries are conducted and the results are analyzed using qualitative analysis methods. The results show that both, organizational and technological issues can cause project failure. Our study contributes to knowledge by reviewing previously identified challenges in terms of their criticality for project failure based on new empirical data, as well as, by identifying previously unknown factors.
Within the last decade, research on torrefaction has gained increasing attention due to its ability to improve the physical properties and chemical composition of biomass residues for further energetic utilisation. While most of the research works focused on improving the energy density of the solid fraction to offer an ecological alternative to coal for energy applications, little attention was paid to the valorisation of the condensable gases as platform chemicals and its ecological relevance when compared to conventional production processes. Therefore, the present study focuses on the ecological evaluation of an innovative biorefinery concept that includes superheated steam drying and the torrefaction of biomass residues at ambient pressure, the recovery of volatiles and the valorisation/separation of several valuable platform chemicals. For a reference case and an alternative system design scenario, the ecological footprint was assessed, considering the use of different biomass residues. The results show that the newly developed process can compete with established bio-based and conventional production processes for furfural, 5-HMF and acetic acid in terms of the assessed environmental performance indicators. The requirements for further research on the synthesis of other promising platform chemicals and the necessary economic evaluation of the process were elaborated.
One of the key challenges for automatic assistance is the support of actors in the operating room depending on the status of the procedure. Therefore, context information collected in the operating room is used to gain knowledge about the current situation. In literature, solutions already exist for specific use cases, but it is doubtful to what extent these approaches can be transferred to other conditions. We conducted a comprehensive literature research on existing situation recognition systems for the intraoperative area, covering 274 articles and 95 cross-references published between 2010 and 2019. We contrasted and compared 58 identified approaches based on defined aspects such as used sensor data or application area. In addition, we discussed applicability and transferability. Most of the papers focus on video data for recognizing situations within laparoscopic and cataract surgeries. Not all of the approaches can be used online for real-time recognition. Using different methods, good results with recognition accuracies above 90% could be achieved. Overall, transferability is less addressed. The applicability of approaches to other circumstances seems to be possible to a limited extent. Future research should place a stronger focus on adaptability. The literature review shows differences within existing approaches for situation recognition and outlines research trends. Applicability and transferability to other conditions are less addressed in current work.
Purpose: Interpretive research in management accounting and control provides rich insights from empirically based studies, but it has been criticised for lacking generalisability and potential subjectivity. On the latter, triangulation is useful, and this paper aims to offer some insights on a triangulation technique thus far not commonly reported in management accounting/control research.
Design/methodology/approach: Drawing on a study of the roles of management accountants in performance management systems, this paper offers some insights from empirical experiences on the use of concept maps as a tool to assist triangulation and improve understanding of complex empirical phenomena.
Findings: The concept maps as utilised revealed additional insights which were not recounted by interviewees during the normal interview time. This is a potentially important finding for consideration of future researchers.
Practical implications: In this paper, how concept maps were used is detailed, and it is hoped that future researchers will find their use beneficial in interview settings.
Originality/value: Thus far, concept maps seem under-utilised in management accounting and control research. This paper gives some initial insights on how they may be used in case study settings.
Motivation: Aim of this project is the automatic classification of total hip endoprosthesis (THEP) components in 2D Xray images. Revision surgeries of total hip arthroplasty (THA) are common procedures in orthopedics and trauma surgery. Currently, around 400.000 procedures per year are performed in the United States (US) alone. To achieve the best possible result, preoperative planning is crucial. Especially if parts of the current THEP system are to be retained.
Methods: First, a ground truth based on 76 X-ray images was created: We used an image processing pipeline consisting of a segmentation step performed by a convolutional neural network and a classification step performed by a support vector machine (SVM). In total, 11 classes (5 pans and 6 shafts) shall be classified.
Results: The ground truth generated was of good quality even though the initial segmentation was performed by technicians. The best segmentation results were achieved using a U-net architecture. For classification, SVM architectures performed much better than additional neural networks.
Conclusions: The overall image processing pipeline performed well, but the ground truth needs to be extended to include a broader variability of implant types and more examples per training class.
Recognition of sleep and wake states is one of the relevant parts of sleep analysis. Performing this measurement in a contactless way increases comfort for the users. We present an approach evaluating only movement and respiratory signals to achieve recognition, which can be measured non-obtrusively. The algorithm is based on multinomial logistic regression and analyses features extracted out of mentioned above signals. These features were identified and developed after performing fundamental research on characteristics of vital signals during sleep. The achieved accuracy of 87% with the Cohen’s kappa of 0.40 demonstrates the appropriateness of a chosen method and encourages continuing research on this topic.
Monodisperse porous poly(glycidyl methacrylate-co-ethylene glycol dimethacrylate) particles are widely applied in different fields, as their pore properties can be influenced and functionalization of the epoxy group is versatile. However, the adjustment of parameters which control morphology and pore properties such as pore volume, pore size and specific surface area is scarcely available. In this work, the effects of the process factors monomer:porogen ratio, GMA:EDMA ratio and composition of the porogen mixture on the response variables pore volume, pore size and specific surface area are investigated using a face centered central composite design. Non-linear effects of the process factors and second order interaction effects between them were identified. Despite the complex interplay of the process factors, targeted control of the pore properties was possible. For each response a response surface model was derived with high predictive power (all R2 predicted > 0.85). All models were tested by four external validation experiments and their validity and predictive power was demonstrated.
This article explores the determinants of people’s growth prospects in survey data as well as the impact of the European recovery fund to future growth. The focus is on the aftermath of the Corona pandemic, which is a natural limit to the sample size. We use Eurobarometer survey data and macroeconomic variables, such as GDP, unemployment, public deficit, inflation, bond yields, and fiscal spending data. We estimate a variety of panel regression models and develop a new simulation-regression methodology due to limitation of the sample size. We find the major determinant of people’s growth prospect is domestic GDP per capita, while European fiscal aid does not significantly matter. In addition, we exhibit with the simulation-regression method novel scientific insights, significant outcomes, and a policy conclusion alike.
The vast majority of state-of-the-art integrated circuits are mixed-signal chips. While the design of the digital parts of the ICs is highly automated, the design of the analog circuitry is largely done manually; it is very time-consuming; and prone to error. Among the reasons generally listed for this is often the attitude of the analog designer. The fact is that many analog designers are convinced that human experience and intuition are needed for good analog design. This is why they distrust the automated synthesis tools. This observation is quite correct, but this is only a symptom of the real problem. This paper shows that this phenomenon is caused by very concrete technical (and thus very rational) issues. These issues lie in the mode of operation of the typical optimization processes employed for the synthesizing tasks. I will show that the dilemma that arises in analog design with these optimizers is the root cause of the low level of automation in analog design. The paper concludes with a review of proposals for automating analog design
Bioenergy production is a new and promising industry in Ecuador. However, a confusing variety of laws, which are spread among different regulating institutions, regulate the agricultural sector. Such dispersion makes it difficult for farmers and businesses to understand applicable rights, duties, regulations and agricultural policies. Moreover, this rather young industry lacks important experience. In the first section of this work, the existing Ecuadorian legislation on bioenergy is presented and analyzed. Then, a brief, thorough analysis and comparison are carried out for experiences not only in developed countries, but also with similar cultural frameworks and comparable climatic conditions. The results are summarized as specific recommendations that have been handed to the National Agricultural Chamber of Ecuador from academia for the proposal of a Unified Agricultural Code established in the Ecuadorian legal hierarchy as an Organic Law.
Continuous manufacturing is becoming more important in the biopharmaceutical industry. This processing strategy is favorable, as it is more efficient, flexible, and has the potential to produce higher and more consistent product quality. At the same time, it faces some challenges, especially in cell culture. As a steady state has to be maintained over a prolonged time, it is unavoidable to implement advanced process analytical technologies to control the relevant process parameters in a fast and precise manner. One such analytical technology is Raman spectroscopy, which has proven its advantages for process monitoring and control mostly in (fed-) batch cultivations. In this study, an in-line flow cell for Raman spectroscopy is included in the cell-free harvest stream of a perfusion process. Quantitative models for glucose and lactate were generated based on five cultivations originating from varying bioreactor scales. After successfully validating the glucose model (Root Mean Square Error of Prediction (RMSEP) of ∼0.2 g/L), it was employed for control of an external glucose feed in cultivation with a glucose-free perfusion medium. The generated model was successfully applied to perform process control at 4 g/L and 1.5 g/L glucose over several days, respectively, with variability of ±0.4 g/L. The results demonstrate the high potential of Raman spectroscopy for advanced process monitoring and control of a perfusion process with a bioreactor and scale-independent measurement method.
Blockchain is a technology for the secure processing and verification of data transactions based on a distributed peer-to-peer network that uses cryptographic processes, consensus algorithms, and backward-linked blocks to make transactions virtually immutable. Within supply chain management, blockchain technology offer potentials in increasing supply chain transparency, visibility, automation, and efficiency. However, its complexity requires future employees to have comprehensive knowledge regarding the functionality of blockchain-based applications in order to be able to apply their benefits to scenarios in supply chain and production. Learning factories represent a suitable environment allowing learners to experience new technologies and to apply them to virtual and physical processes throughout value chains. This paper presents a concept to practically transfer knowledge about the technical functionality of blockchain technology to future engineers and software developers working within supply chains and production operations to sensitize them regarding the advantages of decentralized applications. First, the concept proposes methods to playfully convey immutable backward-linked blocks and the embedment of blockchain smart contracts. Subsequently, the students use this knowledge to develop blockchain-based application scenarios by means of an exemplary product in a learning factory environment. Finally, the developed solutions are implemented with the help of a prototypical decentralized application, which enables a holistic mapping of supply chain events.
In dem Beitrag wurden exemplarisch Möglichkeiten aufgezeigt, die mittels der Verknüpfung unterschiedlicher Technologien zur Steigerung von Genauigkeit und Effizienz bei der Bearbeitung genutzt werden können. Dabei sind Kenntnisse aus unterschiedlichen Bereichen erforderlich. Dies sind sowohl Bearbeitungs- und Prozesstechnologie, die Konstruktion von Maschinen, Vorrichtungen und Werkzeugen, sowie Mess- und Steuerungstechnik. Daneben sind auch neue Geschäftsmodelle und Technologien für die Nutzung und Verfügbarmachung von Daten und Informationen erforderlich.
Das Buch untersucht die Umsetzung der Seidenstraßeninitiative (BRI) in Ostafrika. Die BRI gilt als das zentrale geopolitische und geoökonomische Vorhaben Chinas in der Ära von Präsident Xi Jinping. Durch die Arbeit soll ein Beitrag zur Schließung einiger Forschungslücken geleistet werden, etwa die mangelnde Tiefe von Untersuchungen einzelner BRI-Projekte und die Unterberücksichtigung von Verarbeitungsnarrativen in den teilnehmenden Ländern. Die Leitfrage ist, inwiefern die BRI ein politisches bzw. hegemoniales Projekt des von der KPCh gelenkten Staats-Zivilgesellschafts-Komplexes in Ostafrika ist. Zu deren Beantwortung werden Datenbanken internationaler Organisationen und Policy-Dokumente ausgewertet. Außerdem führt der Verfasser eine qualitative Inhaltsanalyse von Zeitungsartikeln lokaler Medienhäuser in den Ländern Äthiopien, Kenia und Tansania durch, um drei Infrastrukturprojekte zu untersuchen. Die Arbeit verdeutlicht, dass die BRI zur Steigerung der Konnektivität in Ostafrika beiträgt. Gleichzeitig führen die Verdichtung der ökonomischen Beziehungen und die Implementierung der Infrastrukturvorhaben in Ostafrika zu zahlreichen Konsequenzen und konturieren ein hegemoniales Projekt.
Die additive Fertigung hat sich in den vergangenen Jahren wesentlich weiterentwickelt. Dabei wurde die Prozesstechnologie, Anlagen und die Werkstoffe optimiert. Für die industrielle Anwendung auch bei größeren Stückzahlen in der flexiblen Fertigung fehlen noch automatisierte Lösungen für die gesamte Prozesskette. In diesem Beitrag werden Werkzeuge und Technologie für die Reinigung interner Strukturelemente dargestellt.
Background
Although teledermatology has been proven internationally to be an effective and safe addition to the care of patients in primary care, there are few pilot projects implementing teledermatology in routine outpatient care in Germany. The aim of this cluster randomized controlled trial was to evaluate whether referrals to dermatologists are reduced by implementing a store-and-forward teleconsultation system in general practitioner practices.
Methods
Eight counties were cluster randomized to the intervention and control conditions. During the 1-year intervention period between July 2018 and June 2019, 46 general practitioner practices in the 4 intervention counties implemented a store-and-forward teledermatology system with Patient Data Management System interoperability. It allowed practice teams to initiate teleconsultations for patients with dermatologic complaints. In the four control counties, treatment as usual was performed. As primary outcome, number of referrals was calculated from routine health care data. Poisson regression was used to compare referral rates between the intervention practices and 342 control practices.
Results
The primary analysis revealed no significant difference in referral rates (relative risk = 1.02; 95% confidence interval = 0.911–1.141; p = .74). Secondary analyses accounting for sociodemographic and practice characteristics but omitting county pairing resulted in significant differences of referral rates between intervention practices and control practices. Matched county pair, general practitioner age, patient age, and patient sex distribution in the practices were significantly related to referral rates.
Conclusions
While a store-and-forward teleconsultation system was successfully implemented in the German primary health care setting, the intervention's effect was superimposed by regional factors. Such regional factors should be considered in future teledermatology research.
Die Anforderungen an Textilien unterscheiden sich je nach Anwendungsbereich stark, wobei es häufig nicht bei nur einer benötigten Funktionalität bleibt. Im Bereich der Funktions- oder Schutzkleidung bzw. PSA ist es z.B. nötig, die Träger der Kleidung vor UV-Strahlung zu schützen. Gleichzeitig bieten hier selbstreinigende Effekte gewisse Vorteile. Zudem kann eine antimikrobielle Wirkung im Bereich der Funktionskleidung die Bildung unangenehmer Gerüche vermindern, sowie im Bereich der PSA – besonders im Gesundheitswesen – zur Unterbrechung von Infektionsketten beitragen. Eine Möglichkeit, diese 3 gewünschten Funktionen in nur einem Ausrüstungsschritt zu erzielen, ist die Immobilisierung von Titandioxid (TiO2). Dieses wird aber aufgrund einer REACH-Listung kritisch für die Anwendung im textilen Sektor gesehen. Nachteilig ist zudem, dass es seine Wirkung nur unter UV-Einstrahlung entfaltet und damit nicht für den Innenbereich geeignet ist. Alternativ können Photokatalysatoren wie dotierte Zinkoxide (ZnO) verwendet werden, die auch durch Einstrahlung im Bereich des sichtbaren Lichts eine katalytische Aktivität aufweisen, die zur Abtötung von Mikroorganismen und zum Abbau organischer Verschmutzungen führen kann.
The requirements for textiles differ greatly depending on the area of application, whereby it often does not remain with only one required functionality. For example, in the field of functional clothing or protective clothing/PPE, it is necessary to protect the textile’s wearers from UV radiation. At the same time, self-cleaning effects offer certain advantages in that field. In addition, an antimicrobial effect in functional clothing can reduce the formation of unpleasant odors, and in PPE – especially in the healthcare sector – can contribute to the interruption of the chain of infection. One way to achieve these 3 desired functions in just one finishing step is to immobilize titanium dioxide (TiO2). However, TiO2 is viewed critically for application in the textile sector due to a REACH listing. Another disadvantage is that it only takes effect under UV radiation and is therefore not suitable for indoor use. Alternatively, photocatalysts such as doped zinc oxides (ZnO) can be used, which also exhibit catalytic activity through activation by visible light, which can lead to the killing of microorganisms and the degradation of organic soiling.
Schweißerschutzkleidung muss unterschiedlichen Anforderungen genügen. Sie muss u.a. flammfest sein, den Schweißer vor Metallspritzern schützen, die beim Schweißen entstehen, und auch einen Schutz vor UV-Licht sicherstellen, das im Schweißbogen entsteht. Besonders der Schutz vor Metallspritzern wird durch das Flächengewicht der Textilien bestimmt. Der entsprechende Schutzfaktor wird durch Tropfen flüssigen Eisens bestimmt, die auf ein Gewebe fallen. Dabei gilt: je höher das Flächengewicht, desto höher der Schutz vor Schweißspritzern. Jedoch gilt auch: je höher das Flächengewicht, desto schlechter ist der Tragekomfort und desto wärmender ist die Kleidung und damit die körperliche Belastung des Trägers. Durch die Applikation von Nanopartikeln ist es möglich, das benötigte Flächengewicht der Kleidung zu reduzieren.
Schweißerschutzkleidung muss unterschiedlichen Anforderungen genügen. Sie muss u.a. flammfest sein, den Schweißer vor Metallspritzern schützen, die beim Schweißen entstehen, und auch einen Schutz vor UV-Licht sicherstellen, das im Schweißbogen entsteht. Besonders der Schutz vor Metallspritzern wird durch das Flächengewicht der Textilien bestimmt. Der entsprechende Schutzfaktor wird durch Tropfen flüssigen Eisens bestimmt, die auf ein Gewebe fallen. Dabei gilt: je höher das Flächengewicht, desto höher der Schutz vor Schweißspritzern. Jedoch gilt auch: je höher das Flächengewicht, desto schlechter ist der Tragekomfort und desto wärmender ist die Kleidung und damit die körperliche Belastung des Trägers. Durch die Applikation von Nanopartikeln ist es möglich, das benötigte Flächengewicht der Kleidung zu reduzieren.
Lehrbuch zur CAD-Software Creo Parametric und zur Produktdatenverwaltung mit Windchill.
3D-Volumenmodellierung, 3D-Flächenmodellierung, Blechmodellierung, Baugruppen- und Zeichnungserstellung, Definition von Normteilen, Erstellen von Animationen und dynamischen Analysen.
Verfahren zum Umgang mit großen Baugruppen und zur flexiblen Modellierung, Konstruk-tionsvarianten "Top-Down" und "Bottom-Up", Organisation von Konstruktionsprojekten über Skeletttechnik.
Neu: Konstruktion von und mit Mehrkörperobjekten, Rahmenkonstruktion in der Profilumgebung (AFX), intelligente Verbindungen (IFX), Live Simulation und Generatives Design.
Die bedarfsgerechte Steuerung dezentraler thermischer Energiesysteme, wie Kraft-Wärme-Kopplungs- (KWK-) Anlagen und Wärmepumpen, kann einen entscheidenden Beitrag zur Deckung bzw. Reduktion der Residuallast leisten und so für eine Verringerung der konventionellen Reststromversorgung und den damit einhergehenden Treibhausgasemissionen sorgen. Dafür wurde an der Hochschule Reutlingen in mehrjähriger Forschungsarbeit ein prognosebasierter Steuerungsalgorithmus entwickelt. Gegenstand dieses Beitrags bilden neben der Vorstellung eben jenes Steuerungsalgorithmus auch dessen praktische Umsetzungsvarianten: Eine auf einer speicherprogrammierbaren Steuerung (SPS) rein lokal ausführbare Version sowie eine Webservice-Anwendung für den parallelen Betrieb mehrerer Anlagen – ausgehend von einem zentralen Server. Erprobungen am KWK-Prüfstand der Hochschule Reutlingen bestätigen die zuverlässige Funktionsweise des Algorithmus in den verschiedenen Umsetzungsvarianten. Gleichzeitig wird der Vorteil der bedarfsgerechten Steuerung gegenüber dem, insbesondere im Mikro-KWK-Bereich standardmäßig vorliegenden, wärmegeführten Betrieb in Form einer Steigerung der Eigenstromdeckung von bis zu 27 % aufgezeigt. Neben der bedarfsgerechten Steuerung bedient der entwickelte Algorithmus zudem noch ein weiteres Anwendungsgebiet: Den vorhersagbaren KWK-Betrieb, der beispielsweise in Form täglicher Einspeiseprognose im Rahmen des Redispatch 2.0 eingefordert wird. Die Vorhersage des KWK-Betriebs ist dabei auf zwei Weisen möglich: Als erste Option kann der wärmegeführte Betrieb direkt über den Algorithmus abgebildet und prognostiziert werden. Eine andere Möglichkeit stellt wiederum die bedarfsgerechte Steuerung der Anlage dar; der berechnete optimale Fahrplan entspricht dabei gleichzeitig der Betriebsprognose des KWK-Geräts. Damit ist der entwickelte Steuerungsalgorithmus in der Lage, auf unterschiedliche Weisen zum Gelingen der Energiewende beizutragen.
Die Zielsetzung des hier vorgestellten Projekts ist es, eine intelligente Steuerungsalgorithmik für Biogas-Blockheizkraftwerke (Biogas-BHKW) zu entwickeln und zu optimieren. Daran schließt sich eine Testphase an einer realen Biogasanlage an, an der die Algorithmik zu diesem Zweck in die Anlagensteuerung implementiert wird. Um beurteilen zu können inwieweit die Steuerungsalgorithmik einen Beitrag zur Entlastung von Stromnetzen leisten kann, wird für die Versuche neben dem elektrischen Bedarf des landwirtschaftlichen Betriebs, an dem die Anlage angesiedelt ist, zusätzlich die Residuallast des benachbarten Stromnetzes betrachtet. Diese basiert auf Daten vom nächstgelegenen Umspannwerk, die so skaliert werden, dass sie eine Siedlung repräsentieren, die von dem Biogas-BHKW der Anlage mitversorgt werden kann. Die Einbindung der Steuerungsalgorithmik in die Anlagensteuerung erfolgt über eine Kommunikationsstruktur mit einer Datenbank als zentraler Schnittstelle. Eine erste Versuchsreihe, bei der das Biogas-BHKW nach den Fahrplänen der intelligenten Steuerungsalgorithmik geregelt wird, zeigt vielversprechende Ergebnisse. Über die gesamte Versuchsreihe hinweg berechnet die Steuerungsalgorithmik zuverlässig neue Fahrpläne, die vom BHKW weitestgehend auch sehr gut umgesetzt werden. Zudem kann nachgewiesen werden, dass durch den Einsatz der Algorithmik das vorgelagerte Stromnetz entlastet wird.
The United Nations (UN) Global Compact is a call to companies to align their strategies and operations with ten universal principles in the areas of human rights, labor, environment, and anti-corruption, and to take actions that advance societal goals (UN Global Compact 2017, p. 3). The UN Global Compacts’ vision is “to mobilize a global movement of sustainable companies and stakeholder to create the world we want” (UN Global Compact 2021a). It is a global network with local presence all around the world.
The Principles for Responsible Investments (PRI) is “the world’s leading proponent of responsible investment” (PRI 2021a). With the development of six Principles for Responsible Investment, the PRI supports its international network of investor signatories in incorporating the environmental, social, and governance (ESG) factors into their investment and ownership decisions. The goal of PRI is to develop a more sustainable global financial system by encouraging “investors to use responsible investment to enhance returns and better manage risks” (PRI 2021a). This independent financial initiative is supported by the United Nations and linked to the United Nations Environmental Program Finance Initiative (UNEP FI 2021) and the United Nations Global Compact (UN Global Compact 2021).
Values Management System
(2022)
The ValuesManagementSystem (VWS) is a management standard to “provide a sustainable safeguard of a firm and its development, in all dimensions (legal, economic, ecological, social)” (VWSZfW, p. 4). It includes a framework for values-driven governance through self-commitment and self-binding mechanisms. Values promote a sense of identity and give organizations guidance in decision-making. This is especially important in decision-making processes where topics are not clearly ruled by laws and regulations.
VMSZfW must be embedded in the specific business strategy, structure, and culture of an organization. The following four steps describe the implementation of the ValuesManagementSystemZfW: (i) Codify core values of an organization, for instance, with a “mission, vision and values statement” or Code of Ethics, (ii) implement guidelines such as Code of Conduct and specific policies and procedures, (iii) systematize these by establishing management systems such as Compliance and CSR management systems, and (iv) finally organize and establish structures to ensure the strategic direction and operational implementation and review of these processes. The top management shows that values management is taken seriously by their self-commitment to the core values of the company.
Die Informatics Inside ist seit über 13 Jahren ein fester Bestandteil des akademischen Jahres an der Fakultät für Informatik der Hochschule Reutlingen. Die Konferenz wird von Studierenden des Masterstudiengangs Human-Centered Computing selbstständig organisiert und bildet einen wichtigen Teil der wissenschaftlichen Ausbildung. Die Studierenden haben ihre Themen selbst gewählt und nicht selten sind es Fragen, die sie bereits durch das ganze Studium begleiten. Sie bereiten diese im Format einer wissenschaftlichen Ausarbeitung auf, wobei Inhalt, Vollständigkeit und Nachvollziehbarkeit entscheidende Faktoren sind. Die Ergebnisse dieser vertieften Auseinandersetzung mit relevanten Anwendungsthemen der Informatik können Sie in diesem Tagungsband nachlesen. Die Anwendungsdomänen reichen von der Medizin über Wirtschaft bis zu den Medien. Dabei werden aktuelle Fragestellungen des menschzentrierten Einsatzes von künstlicher Intelligenz, Softwaretechnik, Datenanalyse und Kommunikation sowie der digitalen Transformation behandelt. Es wird deutlich, dass der Nutzen von IT-Lösungen für den Menschen im Mittelpunkt der Veranstaltung steht. Das Motto der Veranstaltung „IT´s Future“ ist Programm und macht die Relevanz der Informatik für alle Lebensbereiche sowie die zukünftige Innovations- und Wettbewerbsfähigkeit von Industrie und Forschung deutlich.
This study examines the relevance of integrated reporting quality (IRQ) to capital markets. We investigate whether IRQ benefits capital market participants by improving a firm's information environment, using analyst earnings forecast accuracy as a proxy. Our study focuses specifically on companies that publish integrated reports on a voluntary basis. Based on a scoring model, we assess IRQ and its effects with data from 2015 to 2019 of 101 companies. The results indicate no significant relationship between IRQ and analyst earnings forecast accuracy. Thus, IRQ does not appear to improve a firm's information environment, at least not currently in a voluntary setting. Drawing on previous literature in the field, this study further concludes that integrated reporting (IR) in general has not yet reached its full potential in benefitting capital markets. Potential implications of our results are that the standard setters should work to improve the specificity and rigor of their guidelines, and analysts should become more involved in developing IR guidelines to make them more relevant to their information needs. IR seems to unfold its benefits better in mandatory settings, which could call for regulators to make IR mandatory.
Die Charakterisierung und Beschreibung der komplexen Wechselwirkungen an der Zerspanstelle eines Bearbeitungszentrums beeinflusst die Qualität der hergestellten Bauteile. In diesem Beitrag wird die Messung und Beschreibung der Eigenfrequenzen unterschiedlicher Bearbeitungszentren in Abhängigkeit der bei der Bearbeitung verwendeten Werkzeuge und Bearbeitungsstrategien bezüglich der Auswirkungen auf die Stabilität hergeleitet. Dazu werden die gestellseitigen Resonanzfrequenzen analysiert. Ziel der Untersuchungen ist eine Beschreibung der dynamischen Eigenschaften zur Optimierung der NC-Programmierung.
Sägen ist ein häufig unterschätzter spanender Prozess. Oft kommt das Sägen nur zum Zuschnitt von Rohteilen zum Einsatz. Bei der Bearbeitung von Leichtbauwerkstoffen werden damit jedoch Schichten in Toleranz direkt auf die montagefertigen Konturen zugeschnitten. Zur Steigerung von Qualität und Zuverlässigkeit des Fertigungsprozesses werden maschineninterne und sensorische Daten überwacht, ausgewertet und in den Prozess zurückgekoppelt. Daher kommt es auf die gezielte Kontrolle der entscheidenden Parameter mit möglichst wenigen und robusten Schnittstellen an. Im Rahmen eines ZIM-Kooperationsprojektes (Hochschule Reutlingen, Hema Frickenhausen, Pragmatic Minds Kirchheim) wurde dies für einen Bandsägeprozess erforscht und umgesetzt.
Die additive Fertigung hat sich in den vergangenen Jahren wesentlich weiter entwickelt. Dabei wurde die Prozesstechnologie, Anlagen und die Werkstoffe optimiert. Für die industrielle Anwendung auch bei größeren Stückzahlen in der flexiblen Fertigung fehlen noch automatisierte Lösungen für die gesamte Prozesskette. In diesem Beitrag werden Werkzeuge und Technologie für die Reinigung interner Strukturelemente dargestellt.
This article explores the question of how sustainability and labour law are interrelated. The modern world of work is characterised by the growing social and environmental responsibility of companies. Especially in the post-COVID era, sustainability also plays an increasingly important role in the corporate context, which is also noticeable in the so-called ‘war for talent’. Achieving personal career goals is no longer enough for employees today. Corporate values and in particular the so-called ESG criteria (Environment, Social, Governance) are thus also becoming increasingly important in the employment relationship and in corporate reporting requirements. In terms of social sustainability, labour law instruments can, for example, promote the creation of a discrimination-free working environment, the introduction of flexible working time models or the protection of whistleblowers. From an ecological perspective, labour regulations are also suitable for implementing ‘green mobility’ and other measures to reduce companies’ ecological footprints. Working from home, which experienced a huge boom during the COVID-19 pandemic, is also sustainable, especially from an ecological point of view. Appropriate consideration of these sustainable work tools in future corporate social responsibility (CSR) strategies not only creates a competitive advantage but can also be beneficial in recruitment.
The functionality of existing cyber-physical production systems generally focuses on mapping technologic specifications derived from production requirements. Consequently, such systems base their conception on a structurally mechanistic paradigm. Insofar as these approaches have considered humans, their conception likewise is based on the structurally identical paradigm. Due to the fundamental reorientation towards explicitly human-centered approaches, the fact that essential aspects of the dimension "human" remain unconsidered by the previous paradigm becomes more and more apparent. To overcome such limitations, mapping the "social" dimension requires a structurally different approach. In this paper, an anthropocentric approach is developed based on possible conceptions of the human being, enabling a structural integration of the human being in an extended dimension. Through the model, extending concepts for better integration of the human being in the sense of human-centered approaches, as envisioned in the Industrie 5.0 conception, is possible.
Artificial intelligence is a field of research that is seen as a means of realization regarding digitalization and industry 4.0. It is considered as the critical technology needed to drive the future evolution of manufacturing systems. At the same time, autonomous guided vehicles (AGV) developed as an essential part due to the flexibility they contribute to the whole manufacturing process within manufacturing systems. However, there are still open challenges in the intelligent control of these vehicles on the factory floor. Especially when considering dynamic environments where resources should be controlled in such a way, that they can be adjusted to turbulences efficiently. Therefore, this paper aimed to develop a conceptual framework for addressing a catalog of criteria that considers several machine learning algorithms to find the optimal algorithm for the intelligent control of AGVs. By applying the developed framework, an algorithm is automatically selected that is most suitable for the current operation of the AGV in order to enable efficient control within the factory environment. In future work, this decision-making framework can be transferred to even more scenarios with multiple AGV systems, including internal communication along with AGV fleets. With this study, the automatic selection of the optimal machine learning algorithm for the AGV improves the performance in such a way, that computational power is distributed within a hybrid system linking the AGV and cloud storage in an efficient manner.
Physicians in interventional radiology are exposed to high physical stress. To avoid negative long-term effects resulting from unergonomic working conditions, we demonstrated the feasibility of a system that gives feedback about unergonomic
situations arising during the intervention based on the Azure Kinect camera. The overall feasibility of the approach could be shown.
The proper selection of a demand forecasting method is directly linked to the success of supply chain management (SCM). However, today’s manufacturing companies are confronted with uncertain and dynamic markets. Consequently, classical statistical methods are not always appropriate for accurate and reliable forecasting. Algorithms of Artificial intelligence (AI) are currently used to improve statistical methods. Existing literature only gives a very general overview of the AI methods used in combination with demand forecasting. This paper provides an analysis of the AI methods published in the last five years (2017-2021). Furthermore, a classification is presented by clustering the AI methods in order to define the trend of the methods applied. Finally, a classification of the different AI methods according to the dimensionality of data, volume of data, and time horizon of the forecast is presented. The goal is to support the selection of the appropriate AI method to optimize demand forecasting.
Towards a model for holistic mapping of supply chains by means of tracking and tracing technologies
(2022)
The usage of tracking and tracing technologies not only enables transparency and visibility of supply chains but also offers far-reaching advantages for companies, such as ensuring product quality or reducing supplier risks. Increasing the amount of shared information supports both internal and external planning processes as well as the stability and resilience of globally operating value chains. This paper aims to differentiate and define the functionalities of tracking and tracing technologies that are frequently used interchangeably in literature. Furthermore, this paper incorporates influencing factors impacting a sequencing of the connected world in Industry4.0 supply chain networks. This includes legal influences, the embedment of supply chain-related standards, and new possibilities of emerging technologies. Finally, the results are summarized in a model for the holistic mapping of supply chains by means of tracking and tracing technologies. The resulting technological solutions that can be derived from the model enable companies to address missing elements in order to enable the holistic mapping of supply chain events as well as the transparent representation of a digital shadow throughout the entire supply chain.
The fifth mobile communications generation (5G) offers the deployment scenario of licensed 5G standalone non-public networks (NPNs). Standalone NPNs are locally restricted 5G networks based on 5G New Radio technology which are fully isolated from public networks. NPNs operate on their dedicated core network and offer organizations high data security and customizability for intrinsic network control. Especially in networked and cloud manufacturing, 5G is seen as a promising enabler for delay-sensitive applications such as autonomous mobile robots and robot motion control based on the tactile internet that requires wireless communication with deterministic traffic and strict cycling times. However, currently available industrial standalone NPNs do not meet the performance parameters defined in the 5G specification and standardization process. Current research lacks in performance measurements of download, upload, and time delays of 5G standalone-capable end-devices in NPNs with currently available software and hardware in industrial settings. Therefore, this paper presents initial measurements of the data rate and the round-trip delay in standalone NPNs with various end-devices to generate a first performance benchmark for 5G-based applications. In addition, five end-devices are compared to gain insights into the performance of currently available standalone-capable 5G chipsets. To validate the data rate, three locally hosted measurement methods, namely iPerf3, LibreSpeed and OpenSpeedTest, are used. Locally hosted Ping and LibreSpeed have been executed to validate the time delay. The 5G standalone NPN of Reutlingen University uses licensed frequencies between 3.7-3.8 GHz and serves as the testbed for this study.
Von den Covid-19-Restriktionen wurden im Automobilsektor die Zulieferer wesentlich stärker getroffen als die Fahrzeughersteller. Vor allem die Entwicklung des Working Capitals im ersten Pandemie-Jahr erwies sich als kritisch. Der Beitrag gibt einen Überblick über mögliche Lösungen für eine allseits vorteilhaftere, stabile Supply-Chain-Finanzierung in künftigen Krisen.
Einige Ideen, Erfahrungen und Realitäten für die Studierenden und Bürger in Reutlingen. Zusammengestellt von 50 Studierenden 2020/21 und aus Beiträgen von 40 Institutionen und Unternehmen in und um Reutlingen.
Ein Versuch, sehr konkret am Tatsächlichen zu erklären, was zu mehr Nachhaltigkeit führt, in Reutlingen. Dabei bleibt nicht aus, auch auf Schwachstellen hinzuweisen.
Wenn Studierende und Bürger in den nächsten Jahren bewusst zu mehr Nachhaltigkeit bereit sind, so sind sie mit den Ideen und Realitäten in diesem Projekt auf einem guten Weg.
In our initial DaMoN paper, we set out the goal to revisit the results of “Starring into the Abyss [...] of Concurrency Control with [1000] Cores” (Yu in Proc. VLDB Endow 8: 209-220, 2014). Against their assumption, today we do not see single-socket CPUs with 1000 cores. Instead, multi-socket hardware is prevalent today and in fact offers over 1000 cores. Hence, we evaluated concurrency control (CC) schemes on a real (Intel-based) multi-socket platform. To our surprise, we made interesting findings opposing results of the original analysis that we discussed in our initial DaMoN paper. In this paper, we further broaden our analysis, detailing the effect of hardware and workload characteristics via additional real hardware platforms (IBM Power8 and 9) and the full TPC-C transaction mix. Among others, we identified clear connections between the performance of the CC schemes and hardware characteristics, especially concerning NUMA and CPU cache. Overall, we conclude that no CC scheme can efficiently make use of large multi-socket hardware in a robust manner and suggest several directions on how CC schemes and overall OLTP DBMS should evolve in future.
Current data-intensive systems suffer from scalability as they transfer massive amounts of data to the host DBMS to process it there. Novel near-data processing (NDP) DBMS architectures and smart storage can provably reduce the impact of raw data movement. However, transferring the result-set of an NDP operation may increase the data movement, and thus, the performance overhead. In this paper, we introduce a set of in-situ NDP result-set management techniques, such as spilling, materialization, and reuse. Our evaluation indicates a performance improvement of 1.13 × to 400 ×.
For a long time, most discrete accelerators have been attached to host systems using various generations of the PCI Express interface. However, with its lack of support for coherency between accelerator and host caches, fine-grained interactions require frequent cache-flushes, or even the use of inefficient uncached memory regions. The Cache Coherent Interconnect for Accelerators (CCIX) was the first multi-vendor standard for enabling cache-coherent host-accelerator attachments, and already is indicative of the capabilities of upcoming standards such as Compute Express Link (CXL). In our work, we compare and contrast the use of CCIX with PCIe when interfacing an ARM-based host with two generations of CCIX-enabled FPGAs. We provide both low-level throughput and latency measurements for accesses and address translation, as well as examine an application-level use-case of using CCIX for fine-grained synchronization in an FPGA-accelerated database system. We can show that especially smaller reads from the FPGA to the host can benefit from CCIX by having roughly 33% shorter latency than PCIe. Small writes to the host have a latency roughly 32% higher than PCIe, though, since they carry a higher coherency overhead. For the database use-case, the use of CCIX allowed to maintain a constant synchronization latency even with heavy host-FPGA parallelism.
Even though near-data processing (NDP) can provably reduce data transfers and increase performance, current NDP is solely utilized in read-only settings. Slow or tedious to implement synchronization and invalidation mechanisms between host and smart storage make NDP support for data-intensive update operations difficult. In this paper, we introduce a low-latency cache-coherent shared lock table for update NDP settings in disaggregated memory environments. It utilizes the novel CCIX interconnect technology and is integrated in neoDBMS, a near-data processing DBMS for smart storage. Our evaluation indicates end-to-end lock latencies of ∼80-100ns and robust performance under contention.
Due to its wide-ranging endocrine functions, adipose tissue influences the whole body’s metabolism. Engineering long-term stable and functional human adipose tissue is still challenging due to the limited availability of suitable biomaterials and adequate cell maturation. We used gellan gum (GG) to create manual and bioprinted adipose tissue models because of its similarities to the native extracellular matrix and its easily tunable properties. Gellan gum itself was neither toxic nor monocyte activating. The resulting hydrogels exhibited suitable viscoelastic properties for soft tissues and were stable for 98 days in vitro. Encapsulated human primary adipose-derived stem cells (ASCs) were adipogenically differentiated for 14 days and matured for an additional 84 days. Live-dead staining showed that encapsulated cells stayed viable until day 98, while intracellular lipid staining showed an increase over time and a differentiation rate of 76% between days 28 and 56. After 4 weeks of culture, adipocytes had a univacuolar morphology, expressed perilipin A, and secreted up to 73% more leptin. After bioprinting establishment, we demonstrated that the cells in printed hydrogels had high cell viability and exhibited an adipogenic phenotype and function. In summary, GG-based adipose tissue models show long-term stability and allow ASCs maturation into functional, univacuolar adipocytes.
Hybrid project management is an approach that combines traditional and agile project management techniques. The goal is to benefit from the strengths of each approach, and, at the same time avoid the weaknesses. However, due to the variety of hybrid methodologies that have been presented in the meantime, it is not easy to understand the differences or similarities of the methodologies, as well as, the advantages or disadvantages of the hybrid approach in general. Additionally, there is only fragmented knowledge about prerequisites and success factors for successfully implementing hybrid project management in organizations. Hence, the aim of this study is to provide a structured overview of the current state of research regarding the topic. To address this aim, we have conducted a systematic literature review focusing on a set of specific research questions. As a result, four different hybrid methodologies are discussed, as well as, the definition, benefits, challenges, suitability and prerequisites of hybrid project management. Our study contributes to knowledge by synthesizing and structuring prior work in this growing area of research, which serves as a basis for purposeful and targeted research in the future.
Purpose
Artificial intelligence (AI), in particular deep neural networks, has achieved remarkable results for medical image analysis in several applications. Yet the lack of explainability of deep neural models is considered the principal restriction before applying these methods in clinical practice.
Methods
In this study, we propose a NeuroXAI framework for explainable AI of deep learning networks to increase the trust of medical experts. NeuroXAI implements seven state-of-the-art explanation methods providing visualization maps to help make deep learning models transparent.
Results
NeuroXAI has been applied to two applications of the most widely investigated problems in brain imaging analysis, i.e., image classification and segmentation using magnetic resonance (MR) modality. Visual attention maps of multiple XAI methods have been generated and compared for both applications. Another experiment demonstrated that NeuroXAI can provide information flow visualization on internal layers of a segmentation CNN.
Conclusion
Due to its open architecture, ease of implementation, and scalability to new XAI methods, NeuroXAI could be utilized to assist radiologists and medical professionals in the detection and diagnosis of brain tumors in the clinical routine of cancer patients. The code of NeuroXAI is publicly accessible at https://github.com/razeineldin/NeuroXAI.
Purpose
Context awareness in the operating room (OR) is important to realize targeted assistance to support actors during surgery. A situation recognition system (SRS) is used to interpret intraoperative events and derive an intraoperative situation from these. To achieve a modular system architecture, it is desirable to de-couple the SRS from other system components. This leads to the need of an interface between such an SRS and context-aware systems (CAS). This work aims to provide an open standardized interface to enable loose coupling of the SRS with varying CAS to allow vendor-independent device orchestrations.
Methods
A requirements analysis investigated limiting factors that currently prevent the integration of CAS in today's ORs. These elicited requirements enabled the selection of a suitable base architecture. We examined how to specify this architecture with the constraints of an interoperability standard. The resulting middleware was integrated into a prototypic SRS and our system for intraoperative support, the OR-Pad, as exemplary CAS for evaluating whether our solution can enable context-aware assistance during simulated orthopedical interventions.
Results
The emerging Service-oriented Device Connectivity (SDC) standard series was selected to specify and implement a middleware for providing the interpreted contextual information while the SRS and CAS are loosely coupled. The results were verified within a proof of concept study using the OR-Pad demonstration scenario. The fulfillment of the CAS’ requirements to act context-aware, conformity to the SDC standard series, and the effort for integrating the middleware in individual systems were evaluated. The semantically unambiguous encoding of contextual information depends on the further standardization process of the SDC nomenclature. The discussion of the validity of these results proved the applicability and transferability of the middleware.
Conclusion
The specified and implemented SDC-based middleware shows the feasibility of loose coupling an SRS with unknown CAS to realize context-aware assistance in the OR.
The transmembrane Ca2+ − activated Cl− channel - human bestrophin-1 (hBest1) is expressed in retinal pigment epithelium and mutations of BEST1 gene cause ocular degenerative diseases colectivelly referred to as “bestrophinopathies”. A large number of genetical, biochemical, biophysical and molecular biological studies have been performed to understand the relationship between structure and function of the hBest1 protein and its pathophysiological significance. Here, we review the current understanding of hBest1 surface organization, interactions with membrane lipids in model membranes, and its association with microdomains of cellular membranes. These highlights are significant for modulation of channel activity in cells.
Neuromarketing is already relatively advanced when it comes to researching the principle effect of marketing in the brain. What is often still missing, however, is the transfer of these findings into practice. The reason for this is that research has so far primarily pursued the question of „why?“. For practice, however, the question of „how?“ is much more relevant. This article attempts to answer the latter question, i.e. to bridge the gap between research and practice in the field of retail marketing. Is there a buy button in the consumer´s brain? And if so, how can it be activated? Neuromarketing is a young discipline at the interface of cognitive science, neuroscience and market research. Due to technological progress, neuromarketing can provide important insights for retail, especially insights to explain consumer behaviour. By looking into the customer’s brain, retail companies can address their customers in a more targeted manner and thus gain an advantage over competitors. Especially the influence of emotions and the unconscious play a major role in the purchase decision of consumers. Using the limbic map, customers can be clustered into types based on the characteristics of their emotional systems, for which specific marketing measures can be derived. Best-practice examples from the retail sector show that a targeted approach to specific shopping types in retail can lead to success.
In contrast to classical advertising, event marketing is a dynamic communication instrument that is constantly bringing trends and innovations. The diverse application possibilities and potentials of event marketing make it possible to reach relevant target groups according to the current zeitgeist, to generate brand-relevant realities and worlds of experience, to generate emotions and sympathy values and in this way to create a bond between brand or company and recipients. Enduring brand experience worlds can be seen as a consistent further development of event marketing. Unlike typical branding events, which are limited in time, enduring brand experience worlds create theme worlds that can be experienced, usually for an unlimited period of time. The research paper reflects the development and current state of brand experience worlds. On this basis a systematisation of enduring brand experience worlds is presented and discussed.
Similarities and differences of the various types of enduring brand experience worlds are elaborated and critically appraised.
Addressing the high complexity of brand image measurement, the present research paper investigates the use of artificial neural networks in this particular application context. Since profound insights into the image of a brand are essential for management, the deployment of this learning algorithm is considered as it allows modeling of complex non-linear and multilayered relationships. The conceptual approach presented in the paper is illustrated with the empirical example of the sportswear manufacturer adidas. By using quantitative survey data, a multilayer artificial neural network is created to link the evaluations of specific brand attributes with the overall evaluation of the brand. Based on an analysis of the connection weights between neurons of the artificial neural network, the importance of different brand attributes for the brand evaluation is quantified. This results in concrete implications for brand management practice and potential for further investigations on the use of artificial intelligence in marketing analytics.
We present a multitask network that supports various deep neural network based pedestrian detection functions. Besides 2D and 3D human pose, it also supports body and head orientation estimation based on full body bounding box input. This eliminates the need for explicit face recognition. We show that the performance of 3D human pose estimation and orientation estimation is comparable to the state-of-the-art. Since very few data sets exist for 3D human pose and in particular body and head orientation estimation based on full body data, we further show the benefit of particular simulation data to train the network. The network architecture is relatively simple, yet powerful, and easily adaptable for further research and applications.
The paper describes how eye-tracking can be used to explore electronic patient records (EPR) in a sterile environment. As an information display, we used a system that we developed for the presentation of patient data and for supporting surgical hand disinfection. The eye-tracking was performed using the Tobii Eye Tracker 4C, and the connection between the eye-tracker and the HTML website was realized using the Tobii EyeX Chrome Extension. Interactions with the EPR are triggered by fixations of icons. The interaction was working as intended, but test persons reported a high mental load while using the system.
Ultra wideband real-time locating system for tracking people and devices in the operating room
(2022)
Position tracking within the OR could be one possible input for intraoperative situation recognition. Our approach demonstrates a Real-time Locating System (RTLS) using the Ultra Wideband (UWB) technology to determine the position of people or objects. The UWB RTLS was integrated into the research OR at Reutlingen University and the system’s settings were optimized regarding the four factors accuracy, susceptibility to interference, range, and latency. Therefore, different parameters were adapted and the effects on the factors were compared. Goodtracking quality could be achieved under optimal settings. These results indicate that a UWB RTLS is well suited to determine the position of people and devices in our setting. The feasibility of the system needsto be evaluated under real OR conditions.
With the progress of technology in modern hospitals, an intelligent perioperative situation recognition will gain more relevance due to its potential to substantially improve surgical workflows by providing situation knowledge in real-time. Such knowledge can be extracted from image data by machine learning techniques but poses a privacy threat to the staff’s and patients’ personal data. De-identification is a possible solution for removing visual sensitive information. In this work, we developed a YOLO v3 based prototype to detect sensitive areas in the image in real-time. These are then deidentified using common image obfuscation techniques. Our approach shows that it is principle suitable for de-identifying sensitive data in OR images and contributes to a privacyrespectful way of processing in the context of situation recognition in the OR.
Intraoperative imaging can assist neurosurgeons to define brain tumours and other surrounding brain structures. Interventional ultrasound (iUS) is a convenient modality with fast scan times. However, iUS data may suffer from noise and artefacts which limit their interpretation during brain surgery. In this work, we use two deep learning networks, namely UNet and TransUNet, to make automatic and accurate segmentation of the brain tumour in iUS data. Experiments were conducted on a dataset of 27 iUS volumes. The outcomes show that using a transformer with UNet is advantageous providing an efficient segmentation modelling long-range dependencies between each iUS image. In particular, the enhanced TransUNet was able to predict cavity segmentation in iUS data with an inference rate of more than 125 FPS. These promising results suggest that deep learning networks can be successfully deployed to assist neurosurgeons in the operating room.
Recently, blockchain-based tokens have earned an important role in fields such as the art market or online gaming. First approaches exist, which adopt the potentials of blockchain tokens in supply chain management to increase transparency, visibility, automation, and disintermediation of supply chains. In context, the tokenization of assets in supply chains refers to the practice of creating virtual representations of physical assets on the blockchain. Solutions in supply chain management based on the tokenization of assets vary in terms of application objectives, token types, asset characteristics, as well as the complexities of supply chain events to be mapped on the blockchain. Currently, however, no review exists that summarizes the characteristics of blockchain-based tokens and their scope of applications. This paper provides a clear terminological distinction of existing blockchain token types and therefore distinguishes between fungible tokens, non-fungible tokens, smart non-fungible tokens, and dynamic smart non-fungible tokens. Subsequently, the token types are classified regarding their traceability, modifiability, and authorization to evaluate suitability for mapping assets in supply chains. Given the potential of blockchain in supply chain management, the results of the review serve as a foundation for a practical guide supporting the selection process of suitable token types for industrial applications.
The extracellular matrix (ECM) is the non-cellular part of tissues and represents the natural environment of the cells. Next to structural stability, it provides various physical, chemical, and mechanical cues that strongly regulate and influence cellular behavior and are required for tissue morphogenesis, differentiation, and homeostasis. Due to its promising characteristics, ECM is used in a wide range of tissue engineering and regenerative medicine approaches as a biomaterial for coatings and scaffolds. To date, there are two sources for ECM material. First, native ECM is generated by the removal of the residing cells of a tissue or organ (decellularized ECM; dECM). Secondly, cell-derived ECM (cdECM) can be generated by and isolated from in vitro cultured cells. Although both types of ECM were intensively used for tissue engineering and regenerative medicine approaches, studies directly characterizing and comparing them are rare. Hence, in the first part of this thesis, dECM from adipose tissue and cdECM from stem cells and adipogenic differentiated stem cells from adipose tissue (ASCs) were characterized towards their macromolecular composition, structural features, and biological purity. The dECM was found to exhibit higher levels of collagens and lower levels of sulfated glycosaminoglycans compared to cdECMs. Structural characteristics revealed an immature state of collagen fibers in cdECM samples. The obtained results revealed differences between the two ECMs that can relevantly impact cellular behavior and subsequently experimental outcome and should therefore be considered when choosing a biomaterial for a specific application. The establishment of a functional vascular system in tissue constructs to realize an adequate nutrient supply remains challenging. In the second part, the supporting effect of cdECM on the self‐assembled formation of prevascular‐like structures by microvascular endothelial cells (mvECs) was investigated. It could be observed that cdECM, especially adipogenic differentiated cdECM, enhanced the formation of prevascular-like structures. An increased concentration of proangiogenic factors was found in cdECM substrates. The demonstration of cdECMs capability to induce the spontaneous formation of prevascular‐like structures by mvECs highlights cdECM as a promising biomaterial for adipose tissue engineering. Depending on the purpose of the ECM material chemical modification might be necessary. In the third and last part, the chemical functionalization of cdECM with dienophiles (terminal alkenes, cyclopropene) by metabolic glycoengineering (MGE) was demonstrated. MGE allows the chemical functionalization of cdECM via the natural metabolism of the cells and without affecting the chemical integrity of the cdECM. The incorporated dienophile chemical groups can be specifically addressed via catalysts-free, cell-friendly inverse electron-demand Diels‐Alder reaction. Using this system, the successful modification of cdECM from ASCs with an active enzyme could be shown. The possibility to modify cdECM via a cell-friendly chemical reaction opens up a wide range of possibilities to improve cdECM depending on the purpose of the material. Altogether, this thesis highlighted the differences between adipose dECM and cdECM from ASCs and demonstrated cdECM as a promising alternative to native dECM for application in tissue engineering and regenerative medicine approaches.
Praktische Schwierigkeiten bei der Gestaltung von Einkaufs-bedingungen bestehen oft, weil Käufer unterschiedliche Interessen haben: Bei „just-in-time“-Verträgen wollen Käufer keine Zeit verlieren, um die Ware nach Lieferung zu untersuchen. Sie wollen vielmehr die Ware sofort in den Produktionsprozess geben. Anders ist das bei technisch besonders komplexen Waren. Hier fürchten Käufer, bereits vor Abschluss der Untersuchung mögliche Sachmängel bei Gefahrübergang dem Verkäufer beweisen zu müssen. Gelten BGB/HGB, werden Einkaufsbedingungen nur bedingt diesen Interessen gerecht. Abbedingung der Unter-suchungs- und Rügeobliegenheit und Änderungen der Beweislastverteilung zum Vorteil des Käufers sind dann nicht möglich. Helfen kann hier aber das UN-Kaufrecht: Hier haben Käufergrößere Freiräume, wenn sie Einkaufsbedingungen gestalten.
There is still a great reliance on human expert knowledge during the analog integrated circuit sizing design phase due to its complexity and scale, with the result that there is a very low level of automation associated with it. Current research shows that reinforcement learning is a promising approach for addressing this issue. Similarly, it has been shown that the convergence of conventional optimization approaches can be improved by transforming the design space from the geometrical domain into the electrical domain. Here, this design space transformation is employed as an alternative action space for deep reinforcement learning agents. The presented approach is based entirely on reinforcement learning, whereby agents are trained in the craft of analog circuit sizing without explicit expert guidance. After training and evaluating agents on circuits of varying complexity, their behavior when confronted with a different technology, is examined, showing the applicability, feasibility as well as transferability of this approach.
This paper presents a toolbox in Matlab/Octave for procedural design of analog integrated circuits. The toolbox contains all native functions required by analog designers (namely, schematic-generation, simulation setup and execution, integrated look-up tables and functions for design space exploration) to capture an entire design strategy in an executable script. This script - which we call an Expert Design Plan (EDP) - is capable of executing an analog circuit design fully automatically. The toolbox is integrated in an existing design flow. A bandgap reference voltage circuit is designed with this tool in less than 15 min.
The global demand for resources such as energy, land, or water is constantly increasing. It is therefore not sur- prising that research on the Food-Energy-Water (FEW) nexus has become a scientific as well as a general focus in recent years. A significant increase in publications since 2015 can be observed, and it can be expected that this trend will continue. A multilevel (macro, meso, and micro) perspective is essential, as the FEW nexus has cross- sectoral interdependencies. Several review studies on the FEW nexus can be found in the literature, in general, it can be concluded that the FEW nexus is a multi-disciplinary and complex topic. The studies examined identify essential fields of action for research, policy, and society. However, questions such as what are the main research fields at each level? Is it possible to divide the research into specific clusters? and do the clusters correlate with the levels, and what are the methods of modeling used in the clusters and levels? are still not fully discussed in the literature. An extensive literature review was conducted to get insight into the existing research areas. Especially in such fields as the FEW nexus, the amount of literature can get huge, and a human could get lost analyzing the literature manually. For that, we created word clouds and performed a cluster- and network-analysis to support the selection of most relevant papers for a detailed reading. In 2021, the most publications were published, with 173 publications, which corresponds to a share of 26.6 %. There has been a significant increase since 2015, and it can be expected that this trend will continue in the coming years. Most of the first authors come from the USA (25.4 %), followed by China with 22.4 %. From the word cloud and the top 20 words, which appear in the title and abstract, it can be deduced that the topic water is the most represented. However, the terms system, resource, model, study, change, development, and management also appear to be very important, which indi- cates the importance of a holistic approach to the topic. In total 9 clusters could be identified at the different levels. It can be seen that three clusters form well. For the others, a rather diffuse picture can be observed. In order to find out which topics are hidden behind the individual clusters, 6 publications from each cluster were subjected to a more detailed examination. With these steps, a number of 54 publications were identified for de- tailed consideration. The modeling approaches that are currently being applied in research can be classified into domain-specific tools (e. g. global water models, crop models or global climate models) and into more general tools to perform for example a life cycle analysis, spatial analysis using geographic information system, or system dynamics for a general understanding of the links between the domains. With the domain-specific tools, detailed research questions can be addressed to answer questions for a specific domain. However, these tools have the disadvantage that especially the links between the sectors food, energy, and water are not fully considered. Many implementations that are made today are at lowest level (micro) relate to bounded spatial areas and are derived from macro and meso level goals.
A MATLAB toolbox was developed both for teachers performing quick experimental demonstrations during lectures and for students practicing measurement and frequency analysis procedures. The conceptual purpose was to support fundamental acoustics courses with contents defined by the DEGA recommendation 102. All implemented functions and parameters are visible at once and quickly adjustable by a GUI without submenus. A user manual is provided with explanations of how to get started and how all implemented functions can be applied. The toolbox probably still contains bugs. All users are welcome to inform the author about their experiences and proposals for improvement. In future it is planned to convert "Acoustics" to the MATLAB app designer format as Mathworks announced GUIDE to be replaced. Useful extensions would be additional tabs containing animations of sound propagation phenomena or sound fields caused by different sources.
Ausbildung in der Akustik
(2022)
Die Wissenschaft der Akustik mit ihrer Vielfallt und Interdisziplinarität bietet hervorragende Möglichkeiten an beruflichen Betätigungsfeldern und hat viele von uns in ihren Bann gezogen. Ausbildung in der Akustik bedeutet mehr als Studierenden nur Wissen und Fähigkeiten zu vermitteln. Eigentlich ist nach dem Studium auch der Lernprozess nicht abgeschlossen, sondern wie viele Akustiker:innen meinen, fängt dieser erst dann richtig an. Um eine sehr gute Ausbildung zu gestalten, bedarf es neben Vorbildern an Personen auch Lehrformate, Methoden und Tools. Die folgenden sechs Kurzbeiträge sind Beispiele gelungener Maßnahmen in der Ausbildung der Akustik und sollen anregen, die Qualität in der Lehre stetig zu verbessern.
Highly active MgP catalyst for biodiesel production and polyethylene terephthalate depolymerization
(2022)
A highly active heterogeneous catalyst was designed and employed for two relevant transesterification reactions. i. e. biodiesel production and depolymerization of polyethylene terephthalate (PET). The material was prepared in the presence of pectin by the co-precipitation method followed by calcination at 600°C (MgP). MgP is efficient for biodiesel production, with a yield of ≈99% in 6 h/65°C, and with a molar ratio methanol: oil of 21:1. The reference material (MgR, prepared in absence of pectin) showed a poor catalytic performance in the same experimental conditions. For the methanolysis of PET, 100% PET conversion was obtained with 3 wt% catalyst, 200:1 methanol: PET molar ratio at milder conditions 160°C/4 h, compared to a 33% conversion without the presence of a catalyst. The catalyst showed remarkable stability and negligible deactivation after five consecutive runs. Materials were characterized by SEM, XRD, IR, TGA, and BET.
Mit dem International Mystery Matching (IMM) wurde im International Office der Hochschule Reutlingen (HSRT) eine digital gestützte Möglichkeit geschaffen, neue Mitstudierende oder Kolleginnen und Kollegen in der Pause kennenzulernen. Der vorliegende Beitrag stellt die Einführung und Umsetzung dieses innovativen Angebots zur Vernetzung internationaler und deutscher Studierender sowie von Mitarbeitenden im Hochschulkontext vor. Dabei wird zunächst die Herausforderung der sozialen Integration der internationalen Studierenden erläutert, um anschließend genauer auf das Vorgehen bei der Einführung sowie der Umsetzung des IMM an der HSRT als Lösungsmöglichkeit einzugehen. Ein weiterer Schwerpunkt liegt auf dem Feedback der Studierenden sowie den bisherigen praktischen Erfahrungen mit dem Angebot. Die Ergebnisse einer eigenen Befragung sowie der DAAD-Mobilitätsstudie (BintHo) bestätigen den Bedarf der Zielgruppe an einer besseren Integration im Zusammenhang mit dem Studium an der HSRT.
Modern production systems are characterized by the increasingly use of CPS and IoT networks. However, processing the available information for adaptation and reconfiguration often occurs in relatively large time cycles. It thus does not take advantage of the optimization potential available in the short term. In this paper, a concept is presented that, considering the process information of the individual heterogeneous system elements, detects optimization potentials and performs or proposes adaptation or reconfiguration. The concept is evaluated utilizing a case study in a learning factory. The resulting system thus enables better exploitation of the potentials of the CPPS.
Multi-versioning and MVCC are the foundations of many modern DBMSs. Under mixed workloads and large datasets, the creation of the transactional snapshot can become very expensive, as long-running analytical transactions may request old versions, residing on cold storage, for reasons of transactional consistency. Furthermore, analytical queries operate on cold data, stored on slow persistent storage. Due to the poor data locality, snapshot creation may cause massive data transfers and thus lower performance. Given the current trend towards computational storage and near-data processing, it has become viable to perform such operations in-storage to reduce data transfers and improve scalability. neoDBMS is a DBMS designed for near-data processing and computational storage. In this paper, we demonstrate how neoDBMS performs snapshot computation in-situ. We showcase different interactive scenarios, where neoDBMS outperforms PostgreSQL 12 by up to 5×.
Near-data processing in database systems on native computational storage under HTAP workloads
(2022)
Today’s Hybrid Transactional and Analytical Processing (HTAP) systems, tackle the ever-growing data in combination with a mixture of transactional and analytical workloads. While optimizing for aspects such as data freshness and performance isolation, they build on the traditional data-to-code principle and may trigger massive cold data transfers that impair the overall performance and scalability. Firstly, in this paper we show that Near-Data Processing (NDP) naturally fits in the HTAP design space. Secondly, we propose an NDP database architecture, allowing transactionally consistent in-situ executions of analytical operations in HTAP settings. We evaluate the proposed architecture in state-of-the-art key/value-stores and multi-versioned DBMS. In contrast to traditional setups, our approach yields robust, resource- and cost-effcient performance.
Database management systems and K/V-Stores operate on updatable datasets – massively exceeding the size of available main memory. Tree-based K/V storage management structures became particularly popular in storage engines. B+ -Trees [1, 4] allow constant search performance, however write-heavy workloads yield in inefficient write patterns to secondary storage devices and poor performance characteristics. LSM-Trees [16, 23] overcome this issue by horizontal partitioning fractions of data – small enough to fully reside in main memory, but require frequent maintenance to sustain search performance.
Firstly, we propose Multi-Version Partitioned BTrees (MV-PBT) as sole storage and index management structure in key-sorted storage engines like K/V-Stores. Secondly, we compare MV-PBT against LSM-Trees. The logical horizontal partitioning in MV-PBT allows leveraging recent advances in modern B+ -Tree techniques in a small transparent and memory resident portion of the structure. Structural properties sustain steady read performance, yielding efficient write patterns and reducing write amplification.
We integrated MV-PBT in the WiredTiger [15] KV storage engine. MV-PBT offers an up to 2× increased steady throughput in comparison to LSM-Trees and several orders of magnitude in comparison to B+ -Trees in a YCSB [5] workload.
Switched reluctance motors are particularly attractive due to their simple structure. The control of this machine type requires the instants, to switch the currents in the motor phases in an appropriate sequence. These switching instants are determined either based on a position sensor, or on signals generated by a sensorless method. A very simple sensorless method uses the switching frequency of the hysteresis controllers used for phase current control. This paper first presents an automatic commissioning method for this sensorless method and second a startup procedure, thus enhancing this approach towards an application in industry.
The purpose of this paper sought to develop a collaborative framework that provides wine bottling facilities, wine cellars and their direct supply chain partner guidelines to facilitate a collaborative partnership – aiming to aid responsive decision making and improve reliability. The framework was developed using a triangulation approach, consisting of an in-depth literature review, 14 semi-structured interviews with industry experts and a theoretical case study. The developed framework was presented to wine bottling facilities and their supply chain stakeholders. Indication are that the proposed wine industry collaborative framework should enhance supply chain collaboration and will contribute towards the guidance and facilitation in developing collaboration platforms to align supply chain operations, while improving bottling responsiveness and meeting demand requirements.