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A sleep study is a test used to diagnose sleep disorders and is usually done in sleep laboratories. The golden standard for evaluation of sleep is overnight polysomnography (PSG). Unfortunately, in-lab sleep studies are expensive and complex procedures. Furthermore, with a minimum of 22 wire attachments to the patient for sleep recording, this medical procedure is invasive and unfamiliar for the subjects. To solve this problem, low-cost home diagnostic systems, based on noninvasive recording methods requires further researches.
For this intention it is important to find suitable bio vital parameters for classifying sleep phases WAKE, REM, light sleep and deep sleep without any physical impairment at the same time. We decided to analyse body movement (BM), respiration rate (RR) and heart rate variability (HRV) from existing sleep recordings to develop an algorithm which is able to classify the sleep phases automatically. The preliminary results of this project show that BM, RR and HRV are suitable to identify WAKE, REM and NREM stage.
To assess the quality of a person’s sleep, it is essential to examine the sleep behaviour by identifying the several sleep stages, their durations and sleep cycles. The established and gold standard procedure for sleep stage scoring is overnight polysomnography (PSG) with the Rechtschaffen and Kales (R-K) method. Unfortunately, the conduct of PSG is time-consuming and unfamiliar for the subjects and might have an impact of the recorded data. To avoid the disadvantages with PSG, it is important to make further investigations in low-cost home diagnostic systems. For this intention it is necessary to find suitable bio vital parameters for classifying sleep stages without any physical impairments at the same time. Due to the promising results in several publications we want to analyse existing methods for sleep stage classification based on the parameters body movement,
heartbeat and respiration. Our aim was to find different behaviour patterns in the several sleep stages. Therefore, the average values of 15 whole-night PSG recordings -obtained from the ‘DREAMS
Subjects Database’- where analysed in the light of heartbeat, body movement and respiration with 10 different methods.
To evaluate the quality of a person´s sleep it is essential to identify the sleep stages and their durations. Currently, the gold standard in terms of sleep analysis is overnight polysomnography (PSG), during which several techniques like EEG (eletroencephalogram), EOG (electrooculogram), EMG (electromyogram), ECG (electrocardiogram), SpO2 (blood oxygen saturation) and for example respiratory airflow and respiratory effort are recorded. These expensive and complex procedures, applied in sleep laboratories, are invasive and unfamiliar for the subjects and it is a reason why it might have an impact on the recorded data. These are the main reasons why low-cost home diagnostic systems are likely to be advantageous. Their aim is to reach a larger population by reducing the number of parameters recorded. Nowadays, many wearable devices promise to measure sleep quality using only the ECG and body-movement signals. This work presents an android application developed in order to proof the accuracy of an algorithm published in the sleep literature. The algorithm uses ECG and body movement recordings to estimate sleep stages. The pre-recorded signals fed into the algorithm have been taken from physionet1 online database. The obtained results have been compared with those of the standard method used in PSG. The mean agreement ratios between the sleep stages REM, Wake, NREM-1, NREM-2 and NREM-3 were 38.1%, 14%, 16%, 75% and 54.3%.
Telemedicine is becoming an increasingly important approach to diagnostic, treat or prevent diseases. However, the usage of Information Communication Technologies in healthcare results in a considerable amount of data that must be efficiently and securely transmitted. Many manufacturers provide telemedicine platforms without regarding interoperability, mobility and collaboration. This paper describes a collaborative mobile telemonitoring platform that can use the IEEE 11073 and HL7 communication standards or adapt proprietary protocols. The proposed platform also covers the security and modularity aspects. Furthermore this work introduces an Android-based prototype implementation
Generating synthetic data is a relevant point in the machine learning community. As accessible data is limited, the generation of synthetic data is a significant point in protecting patients' privacy and having more possibilities to train a model for classification or other machine learning tasks. In this work, some generative adversarial networks (GAN) variants are discussed, and an overview is given of how generative adversarial networks can be used for data generation in different fields. In addition, some common problems of the GANs and possibilities to avoid them are shown. Different evaluation methods of the generated data are also described.
Menopause is the permanent cessation of menstruation occurring naturally in women's aging. The most frequent symptoms associated with menopausal phases are mucosal dryness, increased weight and body fat, and changes in sleep patterns. Oral symptoms in menopause derived from saliva flow reduction can lead to dry mouth, ulcers, and alterations of taste and swallowing patterns. However, the oral health phenotype of postmenopausal women has not been characterized. The aim of the study was to determine postmenopausal women's oral phenotype, including medical history, lifestyle, and oral assessment through artificial intelligence algorithms. We enrolled 100 postmenopausal women attending the Dental School of the University of Seville were included in the study. We collected an extensive questionnaire, including lifestyle, medication, and medical history. We used an unsupervised k-means algorithm to cluster the data following standard features for data analysis. Our results showed the main oral symptoms in our postmenopausal cohort were reduced salivary flow and periodontal disease. Relying on the classical assessment of the collected data, we might have a biased evaluation of postmenopausal women. Then, we used artificial intelligence analysis to evaluate our data obtaining the main features and providing a reduced feature defining the oral health phenotype. We found 6 clusters with similar features, including medication affecting salivation or smoking as essential features to obtain different phenotypes. Thus, we could obtain main features considering differential oral health phenotypes of postmenopausal women with an integrative approach providing new tools to assess the women in the dental clinic.
Rapid prototyping platforms reduce development time by allowing quick prototyping of a prototype idea and achieve more time for actual application development with user interfaces. This approach has long been followed in technical platforms, such as the Arduino. To transfer this form of prototyping to wearables, WearIT is presented in this paper.WearIT consists of four components as a wearable prototyping platform: (1) a vest, (2) sensor and actuator shields, (3) its own library and (4) a motherboard consisting of Arduino, Raspberry Pi, a board and a GPS module. As a result, a wearable prototype can be quickly developed by attaching sensor and actuator shields to the WearIT vest. These sensor and actuator shields can then be programmed through the WearIT library. Via Virtual Network Computing (VNC) with a remote computer, the screen contents of the Raspberry Pi can be accessed and the Arduino be programmed.
Autismus-Spektrum-Störungen (ASD) bei Kindern werden häufig zu spät diagnostiziert und die Begleitung der chronischen Krankheit gestaltet sich schwierig. Der vorgestellte Ansatz erlaubt die Behandlung der Kinder in dem bekannten häuslichen Umfeld und versucht die Beziehungen zwischen Schlaf und Verhalten herauszuarbeiten. Die gewonnenen Erkenntnisse sollen die Lebensqualität der Patienten verbessern und den Eltern Hilfestellung geben. Die notwendige infrastrukturelle Unterstützung wird durch medizinisches Fachpersonal geleistet, das auf einen web-basierten Service zurückgreifen kann, der sämtliche Prozesse (Diagnostik, Datenerfassung, -aufzeichnung und Training etc.) begleitet. Die anonymisierten Daten werden in einem Diagnosesystem zentral abgelegt und können so für zukünftige Behandlungsstrategien nutzbar sein. Die umfassende Lösung setzt auf zentrale Elemente von Smart-Homes und AAL auf.
Am Körper getragenen Geräte, sog. Wearables, kommunizieren in der Regel über Bluetooth-Low-Energy (BLE) mit dem Smartphone. Viele Anwendungen, insbesondere im Bereich Gesundheit und AAL, basieren auf der Zusammenarbeit von Wearables mit SmartHome-Geräten. Diese Arbeit präsentiert die Definition und Implementierung von einem neuen BLE Profil für EKG, das Streaming der Signal zum SmartPhone und die Möglichkeit, mehrere solcher Biosignale parallel zu streamen, besitzt. Die Datenarchitektur der App erlaubt eine konfigurierbare Synchronisation der Signal mit dem SmartHome.
The goal of this paper pretends to show how a bed system with an embedded system with sensor is able to analyze a person’s movement, breathing and recognizing the positions that the subject is lying on the bed during the night without any additional physical contact. The measurements are performed with sensors placed between the mattress and the frame. An Intel Edison board was used as an endpoint that served as a communication node from the mesh network to external service. Two nodes and Intel Edison are attached to the bottom of the bed frame and they are connected to the sensors.
Deep learning-based EEG detection of mental alertness states from drivers under ethical aspects
(2021)
One of the most critical factors for a successful road trip is a high degree of alertness while driving. Even a split second of inattention or sleepiness in a crucial moment, will make the difference between life and death. Several prestigious car manufacturers are currently pursuing the aim of automated drowsiness identification to resolve this problem. The path between neuro-scientific research in connection with artificial intelligence and the preservation of the dignity of human individual’s and its inviolability, is very narrow. The key contribution of this work is a system of data analysis for EEGs during a driving session, which draws on previous studies analyzing heart rate (ECG), brain waves (EEG), and eye function (EOG). The gathered data is hereby treated as sensitive as possible, taking ethical regulations into consideration. Obtaining evaluable signs of evolving exhaustion includes techniques that obtain sleeping stage frequencies, problematic are hereby the correlated interference’s in the signal. This research focuses on a processing chain for EEG band splitting that involves band-pass filtering, principal component analysis (PCA), independent component analysis (ICA) with automatic artefact severance, and fast fourier transformation (FFT). The classification is based on a step-by-step adaptive deep learning analysis that detects theta rhythms as a drowsiness predictor in the pre-processed data. It was possible to obtain an offline detection rate of 89% and an online detection rate of 73%. The method is linked to the simulated driving scenario for which it was developed. This leaves space for more optimization on laboratory methods and data collection during wakefulness-dependent operations.
Stress is recognized as a factor of predominant disease and in the future the costs for treatment will increase. The presented approach tries to detect stress in a very basic and easy to implement way, so that the cost for the device and effort to wear it remain low. The user should benefit from the fact that the system offers an easy interface reporting the status of his body in real time. In parallel, the system provides interfaces to pass the obtained data forward for further processing and (professional) analyses, in case the user agrees. The system is designed to be used in every day’s activities and it is not restricted to laboratory use or environments. The implementation of the enhanced prototype shows that the detection of stress and the reporting can be managed using correlation plots and automatic pattern recognition even on a very light weighted microcontroller platform.
The investigation of stress requires to distinguish between stress caused by physical activity and stress that is caused by psychosocial factors. The behaviour of the heart in response to stress and physical activity is very similar in case the set of monitored parameters is reduced to one. Currently, the differentiation remains difficult and methods which only use the heart rate are not able to differentiate between stress and physical activity, without using additional sensor data input. The approach focusses on methods which generate signals providing characteristics that are useful for detecting stress, physical activity, no activity and relaxation.
The purpose of this paper is to examine the effects of perceived stress on traffic and road safety. One of the leading causes of stress among drivers is the feeling of having a lack of control during the driving process. Stress can result in more traffic accidents, an increase in driver errors, and an increase in traffic violations. To study this phenomenon, the Stress Perceived Questionnaire (PSQ) was used to evaluate the perceived stress while driving in a simulation. The study was conducted with participants from Germany, and they were grouped into different categories based on their emotional stability. Each participant was monitored using wearable devices that measured their instantaneous heart rate (HR). The preference for wearable devices was due to their non-intrusive and portable nature. The results of this study provide an overview of how stress can affect traffic and road safety, which can be used for future research or to implement strategies to reduce road accidents and promote traffic safety.
Methods based exclusively on heart rate hardly allow to differentiate between physical activity, stress, relaxation, and rest, that is why an additional sensor like activity/movement sensor added for detection and classification. The response of the heart to physical activity, stress, relaxation, and no activity can be very similar. In this study, we can observe the influence of induced stress and analyze which metrics could be considered for its detection. The changes in the Root Mean Square of the Successive Differences provide us with information about physiological changes. A set of measurements collecting the RR intervals was taken. The intervals are used as a parameter to distinguish four different stages. Parameters like skin conductivity or skin temperature were not used because the main aim is to maintain a minimum number of sensors and devices and thereby to increase the wearability in the future.
Measuring cardiorespiratory parameters in sleep, using non-contact sensors and the Ballistocardiography technique has received much attention due to the low-cost, unobtrusive, and non-invasive method. Designing a user-friendly, simple-to-use, and easy-to-deployment preserving less error-prone remains open and challenging due to the complex morphology of the signal. In this work, using four forcesensitive resistor sensors, we conducted a study by designing four distributions of sensors, in order to simplify the complexity of the system by identifying the region of interest for heartbeat and respiration measurement. The sensors are deployed under the mattress and attached to the bed frame without any interference with the subjects. The four distributions are combined in two linear horizontal, one linear vertical, and one square, covering the influencing region in cardiorespiratory activities. We recruited 4 subjects and acquired data in four regular sleeping positions, each for a duration of 80 seconds. The signal processing was performed using discrete wavelet transform bior 3.9 and smooth level of 4 as well as bandpass filtering. The results indicate that we have achieved the mean absolute error of 2.35 and 4.34 for respiration and heartbeat, respectively. The results recommend the efficiency of a triangleshaped structure of three sensors for measuring heartbeat and respiration parameters in all four regular sleeping positions.
Assistive environments are entering our homes faster than ever. However, there are still various barriers to be broken. One of the crucial points is a personalization of offered services and integration of assistive technologies in common objects and therefore in a regular daily routine. Recognition of sleep patterns for the preliminary sleep study is one of the Health services that could be performed in an undisturbing way. This article proposes the hardware system for the measurement of bio-vital signals necessary for initial sleep study in a nonobtrusive way. The first results confirm the potential of measurement of breathing and movement signals with the proposed system.
An ongoing challenge in our days is to lower the impact on the quality of life caused by dysfunctionality through individual support. With the background of an aging society and continuous increases in costs for care, a holistic solution is needed. This solution must integrate individual needs and preferences, locally available possibilities, regional conditions, professional and informal caregivers and provide the flexibility to implement future requirements. The proposed model is a result of a common initiative to overcome the major obstacles and to center a solution on individual needs caused by dysfunctionality.